GO:0044323

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Name retinoic acid-responsive element binding
Categary Function
Go Slim No
Go Link GO:0044323
Unique Molecular Interactions 51
Total Molecular Interactions 88
Total Single Events 505
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for retinoic acid-responsive element binding. They are ordered first by their pain relevance and then by number of times they were reported for retinoic acid-responsive element binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
2 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
3 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
4 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
5 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
6 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
7 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
8 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
9 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
10 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24
11 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
12 INT312550 DAK Positive_regulation of Rxra 1 0.00 1.48 0.18
13 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
14 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
15 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13
16 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13
17 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
18 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
19 INT201380 RARA Positive_regulation of Regulation of CPOX 1 0.07 0.21 0.08
20 INT278684 Binding of NR1I3 and Rxra 1 0.00 0 0.07
21 INT236932 Binding of Rxra and Pprc1 1 0.00 0.45 0.07
22 INT278685 Binding of CASR and Rxra 1 0.00 0 0.07
23 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05
24 INT285384 Binding of Rare1 and Rxra 1 0.01 0.08 0.05
25 INT307218 Binding of Rxra and D0Nrs1 1 0.00 0.1 0.05
26 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
27 INT297377 Binding of PPARA and Rxra 1 0.02 0.25 0.03
28 INT297375 Binding of VDR and Rxra 1 0.02 0.2 0.03
29 INT297374 Binding of TXNRD1 and Rxra 1 0.01 0.2 0.03
30 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
31 INT182918 Binding of DR1 and RARA 2 0.08 0 0
32 INT182949 Binding of RARA and VDR 1 0.20 0 0
33 INT291715 Binding of DR1 and Rxra 1 0.09 0 0
34 INT182919 TGFBI Regulation of RARA 1 0.29 0.08 0
35 INT291716 Binding of SOD1 and Rxra 1 0.21 0 0
36 INT342366 Binding of Rara and OSBPL1A 1 0.16 0 0
37 INT182961 Binding of RARA and KCNIP3 1 0.21 0.76 0
38 INT236719 Binding of Dr1 and Rxra 1 0.01 0 0
39 INT291682 Positive_regulation of Binding of RARA and TNFRSF10B 1 0.03 0 0
40 INT291712 Binding of Rxra and SPNS1 1 0.04 0 0
41 INT291683 Binding of RARA and TNFRSF10B 1 0.03 0 0
42 INT234440 Binding of PROC and RARA 1 0.00 0.73 0
43 INT291711 Rxra Positive_regulation of VDR 1 0.09 0 0
44 INT342362 Binding of Irs1 and Rara 1 0.15 0 0
45 INT291713 Binding of TNFRSF10B and Rxra 1 0.05 0 0
46 INT225504 Binding of gr and Rara 1 0.02 0 0
47 INT182948 KCNIP3 Regulation of Transcription of RARA 1 0.23 0.55 0
48 INT291681 Positive_regulation of Binding of DR1 and RARA 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for retinoic acid-responsive element binding. They are ordered first by their pain relevance and then by number of times they were reported in retinoic acid-responsive element binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
2 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
3 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
4 INT181186 Binding of Rxra 78 0.35 14.93 4.87
5 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
6 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
7 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
8 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
9 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
10 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
11 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
12 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
13 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
14 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
15 INT67457 Binding of Rara 12 0.24 8.28 1.45
16 INT81400 Binding of RARA 25 0.36 12.93 1.27
17 INT182985 Transcription of RARA 9 0.60 3.52 1.12
18 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
19 INT192090 Localization of Rara 6 0.46 4.15 0.89
20 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
21 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
22 INT48250 Regulation of Rara 3 0.29 2.47 0.83
23 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
24 INT212109 Localization of RARA 5 0.65 3.17 0.79
25 INT91398 Regulation of RARA 7 0.59 5.84 0.67
26 INT114959 Gene_expression of RXRA 2 0.50 1.06 0.63
27 INT114960 Positive_regulation of Gene_expression of RXRA 1 0.32 0.24 0.61
28 INT199723 Localization of Rxra 8 0.59 1.31 0.58
29 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
30 INT114277 Regulation of Gene_expression of Rxra 1 0.28 0.75 0.58
31 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
32 INT182966 Regulation of Gene_expression of RARA 2 0.39 0.12 0.42
33 INT211982 Negative_regulation of Binding of Rara 1 0.28 0.24 0.42
34 INT285391 Binding of RXRA 2 0.03 0.08 0.36
35 INT199725 Negative_regulation of Gene_expression of Rxra 2 0.38 0.3 0.3
36 INT236564 Positive_regulation of Binding of Rxra 2 0.18 1.3 0.24
37 INT10375 Negative_regulation of Gene_expression of RARA 1 0.57 0.97 0.22
38 INT206946 Gene_expression of Rxra 4 0.60 2.2 0.17
39 INT192091 Regulation of Localization of Rara 1 0.04 0.67 0.13
40 INT332915 Positive_regulation of Localization of Rxra 1 0.03 0.3 0.11
41 INT214072 Regulation of Gene_expression of RXRA 1 0.01 0.83 0.09
42 INT166719 Positive_regulation of Rxra 1 0.36 0.31 0.09
43 INT214071 Negative_regulation of Transcription of RARA 3 0.37 1.77 0.07
44 INT182975 Phosphorylation of RARA 2 0.58 0.23 0.07
45 INT256518 Positive_regulation of Transcription of Rxra 1 0.04 0.24 0.06
46 INT291692 Regulation of Binding of Rxra 4 0.32 0.57 0.05
47 INT225406 Transcription of Rxra 3 0.41 0.33 0.03
48 INT256507 Regulation of Transcription of Rxra 1 0.04 0.12 0.03
49 INT291693 Negative_regulation of Binding of Rxra 1 0.22 0.07 0.03
50 INT182990 Positive_regulation of Gene_expression of RARA 5 0.40 3.45 0
51 INT182965 Positive_regulation of Phosphorylation of RARA 1 0.29 0 0
52 INT335229 Regulation of Transcription of RARA 1 0.15 0.95 0
53 INT183002 Positive_regulation of Binding of RARA 1 0.29 1.08 0
54 INT231922 Negative_regulation of Positive_regulation of Rxra 1 0.06 0.33 0
55 INT335226 Negative_regulation of Negative_regulation of RARA 1 0.24 0.71 0
56 INT346487 Negative_regulation of Phosphorylation of RXRA 1 0.01 0.63 0
57 INT291694 Negative_regulation of Localization of Rxra 1 0.22 0 0
58 INT291695 Regulation of Negative_regulation of Rxra 1 0.23 0.14 0
59 INT346494 Phosphorylation of RXRA 1 0.01 0.63 0
60 INT291698 Negative_regulation of Negative_regulation of Rxra 1 0.22 0 0
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