GO:0044325

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Name ion channel binding
Categary Function
Go Slim No
Go Link GO:0044325
Unique Molecular Interactions 245
Total Molecular Interactions 285
Total Single Events 1690
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ion channel binding. They are ordered first by their pain relevance and then by number of times they were reported for ion channel binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254243 Binding of HOMER1 and MRI1 1 0.03 1.99 1.57
2 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
3 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
4 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
5 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
6 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
7 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
8 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
9 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
10 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
11 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98
12 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
13 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
14 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
15 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
16 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
17 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
18 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
19 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
20 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
21 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
22 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
23 INT152948 Homer1 Regulation of Gpr88 1 0.36 0.18 0.75
24 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
25 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
26 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
27 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
28 INT309062 Binding of Trpc1 and Trpc6 1 0.23 0.43 0.6
29 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
30 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
31 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
32 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
33 INT81064 Negative_regulation of Nts Negative_regulation of Gene_expression of Homer1 1 0.01 0 0.48
34 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
35 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
36 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
37 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
38 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
39 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
40 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
41 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
42 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
43 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
44 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
45 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
46 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
47 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
48 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
49 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
50 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
51 INT309057 Binding of Trpc1 and Trpc5 1 0.27 0.21 0.32
52 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
53 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
54 INT118853 Negative_regulation of SRC Negative_regulation of Positive_regulation of STAT3 1 0.41 0.08 0.28
55 INT309058 Binding of Trpc3 and Trpc1 1 0.13 0.23 0.28
56 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
57 INT44091 Binding of ACTN1 and CAMSAP2 1 0.08 0 0.28
58 INT118855 Binding of SRC and GNA14 1 0.01 0.13 0.27
59 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
60 INT345008 Binding of ACTN1 and CSF2 1 0.02 0.53 0.26
61 INT100680 IL4 Positive_regulation of SRC 1 0.42 0.66 0.26
62 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25
63 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
64 INT118858 PRKCA Regulation of Phosphorylation of SRC 1 0.10 0.15 0.24
65 INT118850 GNA14 Positive_regulation of Phosphorylation of SRC 1 0.02 0.15 0.23
66 INT150582 Creb1 Positive_regulation of Gene_expression of Homer1 1 0.00 0 0.22
67 INT174679 Homer1 Regulation of Luc7l3 1 0.02 0.67 0.21
68 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
69 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19
70 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
71 INT58179 Gtf3a Positive_regulation of Gene_expression of Homer1 1 0.07 0.1 0.16
72 INT97515 Binding of Mefv and Pycard 1 0.00 0.78 0.14
73 INT337164 Binding of DIAPH1 and Iqgap1 1 0.53 0.37 0.14
74 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
75 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
76 INT148329 Pkd1 Positive_regulation of Trpv1 1 0.55 0.39 0.13
77 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
78 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
79 INT265982 Homer1 Regulation of Grm5 1 0.04 0.38 0.12
80 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
81 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
82 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
83 INT171390 Src Positive_regulation of Phosphorylation of Egfr 1 0.13 0 0.11
84 INT171389 Src Positive_regulation of Positive_regulation of Mapk1 1 0.16 0 0.11
85 INT171388 Src Positive_regulation of Phosphorylation of Gpbar1 1 0.05 0 0.11
86 INT276064 Src Regulation of Positive_regulation of Rpa1 1 0.02 0.18 0.11
87 INT171387 Ppp1cc Positive_regulation of Phosphorylation of Src 1 0.07 0 0.11
88 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11
89 INT270834 CBX1 Negative_regulation of Transcription of Panx1 1 0.06 0.13 0.1
90 INT270837 Negative_regulation of Panx1 Negative_regulation of Transcription of CBX1 1 0.07 0.13 0.1
91 INT101880 Oxt Positive_regulation of Gene_expression of Homer1 1 0.23 0.14 0.1
92 INT355584 VEGFA Positive_regulation of Positive_regulation of CDH5 1 0.06 1.35 0.09
93 INT270833 Binding of CASP1 and Panx1 1 0.02 0.14 0.09
94 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
95 INT270830 Panx1 Negative_regulation of CASP1 1 0.03 0.09 0.09
96 INT265981 Homer1 Regulation of Localization of Grm5 1 0.04 0.06 0.09
97 INT330955 HOMER1 Positive_regulation of Gene_expression of VDR 1 0.01 0.99 0.08
98 INT270832 Negative_regulation of Panx1 Negative_regulation of Gene_expression of CASP1 1 0.03 0.14 0.08
99 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
100 INT131130 Binding of PKD1 and Krt16 1 0.01 1 0.08
101 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
102 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
103 INT159852 Gene_expression of IL2 Regulation of Gene_expression of ACTN1 1 0.03 0.16 0.07
104 INT265983 Homer1 Regulation of Ryr1 1 0.37 0.15 0.07
105 INT299291 Negative_regulation of PTPN3 Positive_regulation of Phosphorylation of SRC 1 0.07 0.12 0.07
106 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06
107 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
108 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05
109 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05
110 INT265564 Ocln Regulation of Gene_expression of Cdh5 1 0.01 1.03 0.05
111 INT269249 Ptk2 Positive_regulation of Phosphorylation of Src 1 0.13 0.93 0.04
112 INT354971 Binding of HOMER1 and Shank1 1 0.01 0 0.04
113 INT178435 Mapk1 Regulation of Phosphorylation of Src 1 0.03 0.49 0.04
114 INT269250 Ptk2 Positive_regulation of Src 1 0.13 0.86 0.04
115 INT231839 Pcdh8 Positive_regulation of Src 1 0.00 0 0.04
116 INT263377 Abl1 Regulation of Src 1 0.15 0 0.04
117 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04
118 INT263381 Trib3 Regulation of Src 1 0.01 0 0.04
119 INT238113 SRC Regulation of Phosphorylation of STAT3 1 0.46 0 0.04
120 INT221639 Fyn Positive_regulation of Phosphorylation of Cdk5 1 0.14 0.28 0.03
121 INT221624 Binding of Fyn and Plxna1 1 0.01 0.29 0.03
122 INT229006 MIA3 Positive_regulation of Phosphorylation of Src 1 0.02 0.44 0.03
123 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03
124 INT221640 Sema3a Positive_regulation of Phosphorylation of Fyn 1 0.16 0.29 0.03
125 INT221651 Binding of Fyn and Plxna2 1 0.01 0.29 0.03
126 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
127 INT345282 Binding of CASP1 and Pycard 1 0.01 0.3 0.03
128 INT329729 Binding of LCK and Fyn 1 0.00 0.21 0.03
129 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
130 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03
131 INT200820 Epo Positive_regulation of Src 1 0.25 1.41 0.03
132 INT221613 Binding of Cdk5 and Fyn 1 0.10 0.29 0.03
133 INT213905 ESR1 Positive_regulation of SRC 1 0.14 0.31 0.03
134 INT221617 Fyn Positive_regulation of Cdk5 1 0.13 0.28 0.03
135 INT338198 SRC Positive_regulation of STAT3 1 0.11 0.34 0
136 INT290592 Binding of KDR and Cdh5 1 0.07 0.08 0
137 INT278385 Binding of Pycard and Nlrp3 1 0.06 0 0
138 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
139 INT269585 MAPKAP1 Negative_regulation of Phosphorylation of ACTN1 1 0.00 0 0
140 INT299303 SRC Regulation of Phosphorylation of VEGFA 1 0.12 0.05 0
141 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
142 INT201534 RASSF1 Negative_regulation of ID2 1 0.33 1.41 0
143 INT285579 Binding of S100A8 and SRC 1 0.05 0.2 0
144 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
145 INT245158 AD5 Regulation of PKD1 1 0.00 0.44 0
146 INT299305 VEGFA Positive_regulation of Positive_regulation of SRC 1 0.22 0 0
147 INT290590 Binding of Cdh5 and Prom1 1 0.05 0.08 0
148 INT243106 Binding of Crebbp and Src 1 0.05 0.52 0
149 INT299300 SRC Positive_regulation of Phosphorylation of AKT1 1 0.24 0 0
150 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
151 INT279289 TXK Regulation of SRC 1 0.04 0.68 0
152 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
153 INT299296 SRC Regulation of RPTOR 1 0.32 0 0
154 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
155 INT278395 Binding of Pycard and Hps5 1 0.04 0 0
156 INT114712 SRC Positive_regulation of Gene_expression of IGF1R 1 0.63 0.51 0
157 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
158 INT338189 SRC Positive_regulation of HGFAC 1 0.00 0.4 0
159 INT299285 SRC Regulation of Gene_expression of QPCT 1 0.03 0 0
160 INT287077 Chrm2 Positive_regulation of Homer1 1 0.05 0.08 0
161 INT270831 Positive_regulation of Panx1 Positive_regulation of NLRP3 1 0.18 0.1 0
162 INT302174 Positive_regulation of SRC Positive_regulation of Phosphorylation of STAT3 1 0.11 1.01 0
163 INT302142 PTGER3 Positive_regulation of SRC 1 0.09 1.07 0
164 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
165 INT278388 Msu Positive_regulation of Phosphorylation of Lyn 1 0.17 0.12 0
166 INT278381 Binding of Akt1 and Pycard 1 0.00 0 0
167 INT228118 Binding of Fyn and Vav1 1 0.11 0.21 0
168 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
169 INT299308 SRC Regulation of PI3 1 0.20 0 0
170 INT249192 Binding of ACTN1 and S100A9 1 0.01 0 0
171 INT201542 Positive_regulation of RASSF1 Negative_regulation of ID2 1 0.36 1.41 0
172 INT278372 Binding of Syk and Pycard 1 0.06 0 0
173 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
174 INT299298 SRC Negative_regulation of PI3 1 0.19 0 0
175 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0
176 INT338195 Binding of SRC and FIBP 1 0.00 0.31 0
177 INT100265 Hsp90aa1 Regulation of Positive_regulation of Esrrb 1 0.10 0.1 0
178 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
179 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
180 INT309906 Binding of EGF and SRC 1 0.11 0.64 0
181 INT249176 Binding of ITPR3 and TRPC1 1 0.02 0 0
182 INT114713 Binding of IGF1R and SRC 1 0.33 0.6 0
183 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
184 INT249197 Negative_regulation of CA2 Positive_regulation of TRPC1 1 0.16 0 0
185 INT340928 Negative_regulation of SRC Negative_regulation of Positive_regulation of AKT1 1 0.00 0 0
186 INT299294 SRC Regulation of VEGFA 1 0.20 0 0
187 INT238120 SRC Positive_regulation of Positive_regulation of STAT3 1 0.71 0 0
188 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0
189 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0
190 INT238114 Binding of CSK and SRC 1 0.07 0 0
191 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
192 INT201536 RASSF1 Regulation of ID2 1 0.41 1.42 0
193 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
194 INT303987 Binding of LEPR and Fyn 1 0.02 0.62 0
195 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
196 INT201533 RASSF1 Positive_regulation of Gene_expression of ID2 1 0.38 1.41 0
197 INT338196 Binding of SRC and CDCP1 1 0.00 0.31 0
198 INT241537 Negative_regulation of Binding of Abl1 and Src 1 0.04 0.14 0
199 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0
200 INT198019 NPY6R Negative_regulation of Gene_expression of SRC 1 0.06 1.75 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ion channel binding. They are ordered first by their pain relevance and then by number of times they were reported in ion channel binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
2 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
3 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
4 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
5 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67
6 INT60995 Negative_regulation of Positive_regulation of Homer1 9 0.38 1.63 9.63
7 INT15242 Regulation of Gene_expression of Homer1 14 0.62 4.33 9.28
8 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
9 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
10 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
11 INT100222 Binding of Src 9 0.26 5.41 5.37
12 INT100991 Gene_expression of HOMER1 12 0.67 6.96 4.98
13 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
14 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
15 INT53974 Regulation of Homer1 14 0.39 4.71 4.9
16 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
17 INT132700 Positive_regulation of Trpc1 6 0.39 4.33 3.89
18 INT229912 Phosphorylation of Fyn 5 0.42 2.57 3.78
19 INT9798 Negative_regulation of Gene_expression of Homer1 10 0.41 2.04 3.77
20 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
21 INT122327 Regulation of Src 6 0.59 0.59 3.6
22 INT60714 Regulation of Positive_regulation of Homer1 3 0.04 0.64 3.46
23 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
24 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
25 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
26 INT58173 Negative_regulation of Homer1 5 0.43 1 2.79
27 INT82278 Positive_regulation of Positive_regulation of Homer1 5 0.13 2.32 2.73
28 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
29 INT130476 Phosphorylation of Fyn 8 0.80 2.99 2.44
30 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
31 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
32 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
33 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
34 INT98464 Positive_regulation of Positive_regulation of SRC 10 0.67 5.71 1.86
35 INT61845 Transcription of Homer1 9 0.72 2.28 1.85
36 INT148326 Gene_expression of Pkd1 7 0.76 5.38 1.85
37 INT14914 Regulation of Cdh5 5 0.52 4.59 1.85
38 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
39 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7
40 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
41 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
42 INT63520 Localization of Homer1 4 0.75 0.38 1.63
43 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
44 INT98455 Regulation of Src 4 0.20 1.76 1.48
45 INT145127 Positive_regulation of Gene_expression of Trpc1 4 0.30 3.56 1.46
46 INT259086 Binding of Trpc1 3 0.22 1.27 1.37
47 INT82279 Regulation of Negative_regulation of Homer1 1 0.02 0 1.36
48 INT88855 Negative_regulation of Hsp90aa1 4 0.54 2.16 1.34
49 INT114715 Binding of SRC 8 0.36 4.26 1.32
50 INT138085 Regulation of Trpc1 2 0.32 0.53 1.28
51 INT138084 Localization of Trpc1 4 0.79 0.2 1.26
52 INT182474 Gene_expression of Cdh5 17 0.57 14.58 1.23
53 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
54 INT148321 Positive_regulation of Gene_expression of Pkd1 5 0.68 2.93 1.21
55 INT114568 Negative_regulation of Trpc1 4 0.41 0.56 1.19
56 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15
57 INT130477 Negative_regulation of Fyn 3 0.29 1.59 1.14
58 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
59 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
60 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
61 INT100992 Regulation of Gene_expression of HOMER1 2 0.10 0.74 1.06
62 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
63 INT259087 Negative_regulation of Binding of Trpc1 1 0.17 1.04 1.05
64 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04
65 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
66 INT100612 Positive_regulation of Hsp90aa1 4 0.64 5.3 1.01
67 INT317504 Protein_catabolism of Src 1 0.49 0.13 0.97
68 INT71917 Gene_expression of ACTN1 4 0.24 2.27 0.96
69 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
70 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
71 INT149383 Binding of Lyn 1 0.36 1.14 0.91
72 INT88861 Positive_regulation of Gene_expression of Hsp90aa1 4 0.64 7.43 0.9
73 INT9797 Binding of Homer1 2 0.48 1.14 0.9
74 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
75 INT146940 Gene_expression of Fyn 2 0.52 2.76 0.83
76 INT118004 Positive_regulation of Gene_expression of SRC 13 0.49 11.05 0.8
77 INT143912 Localization of Src 4 0.48 2.51 0.78
78 INT85678 Binding of Arrb1 1 0.20 0.09 0.78
79 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
80 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
81 INT254244 Localization of HOMER1 1 0.19 0.68 0.66
82 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
83 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
84 INT44092 Binding of ACTN1 7 0.20 1.52 0.62
85 INT221935 Gene_expression of TRPC1 5 0.45 0.53 0.62
86 INT138235 Positive_regulation of Pycard 2 0.33 1.66 0.62
87 INT88859 Transcription of Hsp90aa1 1 0.58 1.51 0.6
88 INT166086 Binding of Hsp90aa1 1 0.28 0.08 0.6
89 INT88857 Negative_regulation of Transcription of Hsp90aa1 1 0.36 1.52 0.6
90 INT76505 Positive_regulation of Transcription of Homer1 3 0.21 0.48 0.59
91 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
92 INT138239 Localization of Pycard 2 0.53 1.05 0.58
93 INT138238 Positive_regulation of Localization of Pycard 1 0.33 0.66 0.58
94 INT84854 Regulation of Transcription of Homer1 1 0.00 0.15 0.57
95 INT149350 Regulation of Gene_expression of Trpc1 1 0.19 1.13 0.57
96 INT249509 Gene_expression of Fyn 2 0.35 1.79 0.56
97 INT143910 Negative_regulation of Positive_regulation of Src 1 0.27 0.14 0.56
98 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
99 INT270809 Gene_expression of Panx1 1 0.69 0.59 0.55
100 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
101 INT92523 Phosphorylation of Homer1 3 0.63 0.15 0.52
102 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
103 INT155214 Negative_regulation of ACTN1 1 0.28 0.16 0.51
104 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
105 INT82608 Positive_regulation of Phosphorylation of SRC 3 0.49 1.28 0.48
106 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
107 INT249504 Localization of Src 1 0.36 0.32 0.46
108 INT254317 Negative_regulation of Pycard 5 0.42 3.13 0.45
109 INT88856 Negative_regulation of Gene_expression of Hsp90aa1 2 0.39 2.31 0.45
110 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44
111 INT98456 Negative_regulation of Src 17 0.42 8.3 0.42
112 INT140496 Positive_regulation of TRPC1 3 0.29 0.43 0.42
113 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
114 INT148322 Localization of Pkd1 1 0.79 1.07 0.41
115 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
116 INT165349 Positive_regulation of Positive_regulation of Trpc1 1 0.39 0.74 0.39
117 INT156120 Localization of Arrb1 1 0.00 0 0.38
118 INT156119 Positive_regulation of Localization of Arrb1 1 0.00 0 0.38
119 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
120 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
121 INT155215 Regulation of ACTN1 1 0.30 0.17 0.37
122 INT270810 Localization of Panx1 1 0.67 0.33 0.34
123 INT249525 Positive_regulation of Gene_expression of Fyn 1 0.21 0.23 0.34
124 INT138051 Negative_regulation of Positive_regulation of SRC 3 0.57 0.84 0.33
125 INT209911 Protein_catabolism of Pycard 2 0.11 1.58 0.33
126 INT249533 Regulation of Localization of Src 1 0.22 0.22 0.32
127 INT249523 Regulation of Localization of Fyn 1 0.19 0.22 0.32
128 INT249516 Negative_regulation of Gene_expression of Fyn 1 0.18 0.23 0.32
129 INT86669 Positive_regulation of HOMER1 2 0.30 1.37 0.31
130 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
131 INT339435 Binding of Cdh5 1 0.31 3.37 0.3
132 INT273978 Gene_expression of Pycard 2 0.10 1.96 0.29
133 INT249510 Localization of Fyn 1 0.32 0.22 0.29
134 INT77654 Regulation of Gene_expression of Hsp90aa1 4 0.62 2.41 0.28
135 INT270811 Negative_regulation of Panx1 1 0.52 0.4 0.27
136 INT157906 Binding of TRPC1 2 0.32 0.91 0.26
137 INT171374 Binding of Src 2 0.13 0.44 0.24
138 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
139 INT216978 Binding of Pycard 6 0.25 2.93 0.22
140 INT148791 Negative_regulation of Phosphorylation of Cdh5 2 0.07 0.97 0.22
141 INT164162 Negative_regulation of Phosphorylation of SRC 3 0.29 2.12 0.21
142 INT148790 Phosphorylation of Cdh5 2 0.14 0.97 0.21
143 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2
144 INT146414 Binding of Pacs1 2 0.30 0.06 0.2
145 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2
146 INT146413 Positive_regulation of Binding of Pacs1 1 0.40 0.06 0.2
147 INT235725 Regulation of SRC 7 0.44 4.71 0.19
148 INT338874 Binding of Fyn 1 0.08 0.53 0.19
149 INT270812 Transcription of Panx1 1 0.54 0.26 0.19
150 INT270803 Negative_regulation of Transcription of Panx1 1 0.33 0.26 0.19
151 INT269610 Phosphorylation of ACTN1 1 0.03 0.19 0.18
152 INT182476 Positive_regulation of Gene_expression of Cdh5 5 0.40 1.65 0.17
153 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
154 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
155 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
156 INT249526 Positive_regulation of Localization of Src 1 0.24 0.1 0.16
157 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15
158 INT277989 Positive_regulation of CDH5 3 0.11 1.66 0.15
159 INT199521 Protein_catabolism of PKD1 2 0.96 0.39 0.15
160 INT148323 Binding of Pkd1 1 0.37 0.5 0.15
161 INT304452 Regulation of Lyn 1 0.17 0 0.15
162 INT262796 Positive_regulation of Pycard 12 0.22 6.5 0.14
163 INT44093 Positive_regulation of ACTN1 3 0.24 0 0.14
164 INT337163 Localization of DIAPH1 1 0.68 0.41 0.14
165 INT97512 Binding of Pycard 1 0.01 0.78 0.14
166 INT148792 Positive_regulation of Phosphorylation of Cdh5 1 0.08 0 0.14
167 INT148324 Phosphorylation of Pkd1 1 0.81 0.52 0.14
168 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
169 INT266328 Positive_regulation of Cdh5 4 0.40 0.77 0.12
170 INT142970 Positive_regulation of Gene_expression of ID2 2 0.40 2.39 0.11
171 INT142968 Negative_regulation of Gene_expression of ID2 1 0.19 0.98 0.11
172 INT100990 Positive_regulation of Gene_expression of HOMER1 1 0.17 0.15 0.1
173 INT142971 Negative_regulation of Positive_regulation of ID2 1 0.20 0.69 0.09
174 INT142969 Positive_regulation of ID2 1 0.21 0.68 0.09
175 INT299357 Localization of SRC 1 0.51 0 0.09
176 INT309074 Negative_regulation of Gene_expression of Trpc1 1 0.25 0.16 0.09
177 INT28560 Positive_regulation of Pacs1 1 0.07 1.33 0.09
178 INT239985 Negative_regulation of Cdh5 2 0.27 0.47 0.08
179 INT339433 Localization of Cdh5 1 0.48 0.37 0.08
180 INT270808 Positive_regulation of Gene_expression of Panx1 1 0.62 0.13 0.08
181 INT339438 Negative_regulation of Localization of Cdh5 1 0.27 0.37 0.08
182 INT159857 Positive_regulation of Binding of ACTN1 1 0.08 0.16 0.08
183 INT188176 Positive_regulation of Gene_expression of CDH5 3 0.32 0.75 0.07
184 INT338740 Transcription of Src 1 0.43 1.24 0.07
185 INT199074 Positive_regulation of Fyn 1 0.18 0.05 0.07
186 INT159859 Regulation of Binding of ACTN1 1 0.04 0.16 0.07
187 INT286583 Localization of PKD2 1 0.35 0.17 0.06
188 INT270807 Positive_regulation of Localization of Panx1 1 0.39 0.05 0.06
189 INT211006 Binding of PKD1 6 0.22 2.69 0.05
190 INT261879 Binding of PKD2 3 0.13 2.59 0.05
191 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05
192 INT238187 Regulation of Positive_regulation of SRC 2 0.26 1.37 0.05
193 INT315847 Positive_regulation of Negative_regulation of Lyn 1 0.18 0.61 0.05
194 INT239993 Negative_regulation of Gene_expression of Cdh5 3 0.31 0.76 0.04
195 INT149789 Positive_regulation of Phosphorylation of Fyn 2 0.67 0.31 0.04
196 INT100989 Regulation of HOMER1 1 0.10 0.06 0.04
197 INT326432 Regulation of Positive_regulation of Pycard 1 0.07 0.31 0.04
198 INT262801 Regulation of Gene_expression of Pycard 1 0.08 1.8 0.04
199 INT269625 Positive_regulation of Phosphorylation of ACTN1 1 0.02 0.08 0.04
200 INT270806 Positive_regulation of Panx1 1 0.62 0.3 0.04
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