GO:0044419

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Name interspecies interaction between organisms
Categary Process
Go Slim No
Go Link GO:0044419
Unique Molecular Interactions 1749
Total Molecular Interactions 2534
Total Single Events 17323
Pain Genes Associated 156

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interspecies interaction between organisms. They are ordered first by their pain relevance and then by number of times they were reported for interspecies interaction between organisms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
3 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
4 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
5 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
6 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
7 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
8 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
9 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
10 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81
11 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
12 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
13 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
14 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
15 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
16 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
17 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
18 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64
19 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
20 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61
21 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
22 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
23 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
24 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
25 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
26 INT55837 Binding of HLA-B and PHB2 3 0.20 3.52 1.37
27 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
28 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
29 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
30 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
31 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
32 INT51388 Binding of CSF2 and RPLP0 1 0.11 1.8 1.27
33 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
34 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
35 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
36 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
37 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
38 INT35459 POMC Negative_regulation of Gene_expression of IL16 1 0.45 0 1.19
39 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
40 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
41 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
42 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
43 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12
44 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
45 INT107269 Binding of HLA-A and NCR3 1 0.35 1.42 1.1
46 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1
47 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
48 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
49 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
50 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
51 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
52 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07
53 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
54 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
55 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
56 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
57 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
58 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
59 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02
60 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02
61 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
62 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
63 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98
64 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
65 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
66 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
67 INT289173 PYCARD Regulation of MFGE8 1 0.05 0 0.96
68 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
69 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
70 INT182210 Binding of CXCR4 and CXCL13 1 0.32 1.25 0.95
71 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
72 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
73 INT62109 SLC25A4 Negative_regulation of Localization of Gh 1 0.06 0 0.94
74 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
75 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
76 INT182205 Binding of CXCL5 and CXCR4 1 0.29 1.24 0.94
77 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
78 INT182195 Binding of CXCL1 and CXCR4 1 0.13 1.25 0.94
79 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
80 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93
81 INT143323 Binding of HLA-B and HP 1 0.04 0.95 0.93
82 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92
83 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91
84 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
85 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
86 INT62111 SLC25A4 Negative_regulation of Regulation of Ghrh 1 0.41 0 0.9
87 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
88 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
89 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
90 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
91 INT116771 Binding of MAVS and MRGPRX1 1 0.00 0.51 0.89
92 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88
93 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
94 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
95 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
96 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
97 INT104126 STAT3 Regulation of Phospho1 1 0.00 0.06 0.86
98 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
99 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
100 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
101 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
102 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
103 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
104 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
105 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
106 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
107 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
108 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
109 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
110 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
111 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
112 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
113 INT260895 CRH Regulation of MMP1 1 0.11 0.31 0.74
114 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
115 INT162240 Binding of COL7A1 and MMP1 1 0.03 0.86 0.73
116 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73
117 INT72229 Binding of NFKBIL1 and BTRC 1 0.00 0 0.73
118 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
119 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
120 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
121 INT182201 Binding of CXCR5 and CXCR4 1 0.36 1.15 0.72
122 INT182202 Binding of CXCR2 and CXCR4 1 0.31 1.15 0.72
123 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71
124 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
125 INT239538 Binding of CXCR4 and CALCRL 1 0.00 0.35 0.71
126 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
127 INT16048 MAX Positive_regulation of SLC25A4 1 0.50 0 0.71
128 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
129 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
130 INT314593 Zbp1 Negative_regulation of Gene_expression of Isg15 1 0.28 0.17 0.7
131 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
132 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
133 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
134 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
135 INT314589 Zbp1 Negative_regulation of Gene_expression of Oasl1 1 0.31 0.17 0.7
136 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
137 INT314595 Zbp1 Negative_regulation of Gene_expression of Samhd1 1 0.05 0.17 0.7
138 INT28711 Binding of HLA-B and MRAP 2 0.23 0.96 0.69
139 INT27690 Ins1 Negative_regulation of GYPA 1 0.00 0.73 0.69
140 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 0.04 0.59 0.69
141 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68
142 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
143 INT157935 Negative_regulation of TRPV1 Negative_regulation of Gene_expression of MMP1 1 0.42 0.1 0.68
144 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
145 INT28079 POMC Regulation of ANPEP 1 0.08 0.16 0.66
146 INT334127 Acsm3 Positive_regulation of Vcam1 1 0.24 1.61 0.66
147 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
148 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
149 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
150 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
151 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
152 INT66603 TFF2 Positive_regulation of Gene_expression of ICAM1 1 0.02 0 0.64
153 INT106247 Binding of CCR5 and CCL4 1 0.54 0.06 0.64
154 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
155 INT169101 Binding of HLA-A and HLA-DRB1 1 0.24 1.09 0.63
156 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
157 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
158 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
159 INT346141 ADM Positive_regulation of Gene_expression of ICAM1 1 0.19 1.75 0.63
160 INT66601 WDR87 Positive_regulation of Gene_expression of ICAM1 1 0.00 0 0.63
161 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
162 INT66604 SARDH Positive_regulation of Gene_expression of ICAM1 1 0.01 0 0.63
163 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
164 INT98953 Positive_regulation of Binding of SP1 and CFHR4 1 0.00 0 0.62
165 INT98954 Binding of SP1 and CFHR4 1 0.00 0 0.61
166 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
167 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
168 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
169 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
170 INT122096 Binding of HLA-B and SFTPA1 2 0.04 1.81 0.6
171 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
172 INT138886 Binding of F11r and Tjp1 1 0.13 0.86 0.6
173 INT92996 Binding of VCAM1 and GORASP1 1 0.39 0.33 0.6
174 INT174504 Binding of HLA-B and KIR3DL2 2 0.24 1.69 0.59
175 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
176 INT87683 Binding of HLA-B and Prnd 1 0.00 0.59 0.59
177 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
178 INT162742 Binding of HLA-A and KIR3DL1 1 0.40 0.68 0.58
179 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
180 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57
181 INT157934 TRPV1 Positive_regulation of Positive_regulation of MMP1 1 0.45 0.07 0.57
182 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
183 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57
184 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
185 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
186 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
187 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
188 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
189 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
190 INT66600 TFF2 Regulation of Positive_regulation of ICAM1 1 0.01 0 0.56
191 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
192 INT73920 Binding of CCNT1 and CYP2B6 1 0.19 0.17 0.56
193 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
194 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
195 INT103184 Prkaca Positive_regulation of Phosphorylation of CRTC1 1 0.01 0.57 0.55
196 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
197 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55
198 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
199 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54
200 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported for interspecies interaction between organisms. They are ordered first by their pain relevance and then by number of times they were reported in interspecies interaction between organisms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1878 Binding of HLA-B 440 0.48 321.16 127.36
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6
4 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37
5 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
6 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
7 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
8 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
9 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84
10 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28
11 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
12 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72
13 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
14 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
15 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
16 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
17 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96
18 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
19 INT19330 Binding of HLA-A 99 0.48 76.26 22.85
20 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
21 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08
22 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61
23 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
24 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
25 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
26 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
27 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72
28 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
29 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29
30 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
31 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
32 INT103210 Localization of MMP1 43 0.78 12.15 15.13
33 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15
34 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
35 INT107585 Gene_expression of CCR2 35 0.71 26.44 14.75
36 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31
37 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
38 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1
39 INT132178 Binding of CD80 41 0.47 15.55 12.98
40 INT6322 Gene_expression of Ceacam1 46 0.75 32.13 12.46
41 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
42 INT36287 Binding of CD4 96 0.47 58.93 11.88
43 INT65713 Localization of ICAM1 42 0.81 39.55 11.49
44 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36
45 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
46 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96
47 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76
48 INT35460 Gene_expression of IL16 45 0.75 48.71 10.5
49 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
50 INT16404 Regulation of CD4 54 0.61 33.05 10.29
51 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01
52 INT102525 Gene_expression of CCR3 24 0.71 16.19 10
53 INT19620 Binding of CD86 30 0.47 12.01 9.89
54 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84
55 INT80549 Binding of ICAM1 53 0.47 42.76 9.72
56 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5
57 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46
58 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
59 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
60 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
61 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08
62 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06
63 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
64 INT66213 Localization of RELA 63 0.78 14.71 8.77
65 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69
66 INT3353 Localization of HLA-B 25 0.75 16.05 8.62
67 INT89292 Positive_regulation of CCR5 27 0.70 15.12 8.59
68 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58
69 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52
70 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42
71 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37
72 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
73 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
74 INT93914 Gene_expression of CD80 70 0.75 36.35 7.74
75 INT5284 Regulation of HLA-B 25 0.59 12.91 7.74
76 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68
77 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
78 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64
79 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
80 INT5381 Gene_expression of FYN 18 0.75 7.65 7.35
81 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
82 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
83 INT91758 Binding of CCR5 28 0.45 20.16 7.07
84 INT12771 Positive_regulation of IKBKG 27 0.69 5.99 7.02
85 INT17049 Localization of CD4 57 0.75 35.33 6.89
86 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84
87 INT35462 Negative_regulation of Gene_expression of IL16 9 0.53 2.04 6.83
88 INT157465 Positive_regulation of Gene_expression of CX3CR1 5 0.49 8.9 6.62
89 INT48555 Binding of SP1 30 0.46 11.38 6.53
90 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35
91 INT127023 Negative_regulation of Gene_expression of Vcam1 24 0.59 20.39 6.28
92 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25
93 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
94 INT95607 Regulation of MMP1 19 0.60 7.86 6.18
95 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
96 INT27628 Gene_expression of IL2RG 28 0.75 20.95 6.16
97 INT107315 Negative_regulation of CCR5 22 0.57 13.82 6.11
98 INT4697 Positive_regulation of Gene_expression of HLA-B 32 0.61 17.32 5.97
99 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
100 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94
101 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93
102 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
103 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
104 INT333909 Positive_regulation of Gene_expression of HDAC1 1 0.44 14.15 5.9
105 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
106 INT117189 Binding of CXCR4 34 0.37 24.27 5.81
107 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
108 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68
109 INT113254 Positive_regulation of MFGE8 13 0.09 2.52 5.56
110 INT3768 Negative_regulation of ANPEP 16 0.59 4.96 5.52
111 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51
112 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5
113 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49
114 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
115 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
116 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43
117 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41
118 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
119 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
120 INT113112 Negative_regulation of CXCR4 39 0.58 28.28 5.36
121 INT60585 Regulation of TP53 59 0.59 54.55 5.21
122 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15
123 INT2072 Localization of AMBP 33 0.65 37.58 4.84
124 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82
125 INT105403 Positive_regulation of Gene_expression of CCR3 10 0.60 7.99 4.74
126 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
127 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
128 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
129 INT2213 Regulation of EP300 10 0.54 4.72 4.5
130 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
131 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
132 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41
133 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41
134 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
135 INT35028 Positive_regulation of IL2RG 14 0.47 10.05 4.36
136 INT130083 Positive_regulation of Positive_regulation of Vcam1 8 0.36 5.81 4.31
137 INT35461 Positive_regulation of Gene_expression of IL16 22 0.67 25.57 4.24
138 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18
139 INT12772 Positive_regulation of Positive_regulation of IKBKG 9 0.69 0.84 4.12
140 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09
141 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08
142 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07
143 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
144 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
145 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86
146 INT99509 Gene_expression of CFLAR 25 0.75 22.59 3.78
147 INT289208 Gene_expression of MFGE8 13 0.08 0.25 3.7
148 INT121818 Binding of STAT3 25 0.47 11.16 3.67
149 INT94431 Transcription of MMP1 14 0.56 4.1 3.66
150 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
151 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55
152 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
153 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
154 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34
155 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
156 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3
157 INT19331 Positive_regulation of HLA-A 12 0.49 7.72 3.28
158 INT18477 Protein_catabolism of ANPEP 7 0.79 0.41 3.26
159 INT48902 Gene_expression of ACE2 22 0.78 17.91 3.24
160 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
161 INT85260 Negative_regulation of ATF7IP 14 0.41 7.08 3.17
162 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
163 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
164 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08
165 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
166 INT77604 Positive_regulation of Binding of VCAM1 4 0.47 6.54 3.06
167 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05
168 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
169 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04
170 INT120067 Positive_regulation of Gene_expression of CCR2 10 0.46 5.13 3.02
171 INT12770 Negative_regulation of Positive_regulation of IKBKG 7 0.56 0.34 3.02
172 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
173 INT92335 Gene_expression of TBK1 11 0.28 8.98 3
174 INT8103 Binding of TP53 46 0.44 40.2 2.96
175 INT16959 Positive_regulation of Binding of HLA-B 8 0.50 6.77 2.96
176 INT2249 Negative_regulation of Binding of HLA-B 5 0.54 6.82 2.94
177 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92
178 INT54749 Binding of BTRC 7 0.09 0.88 2.9
179 INT155486 Positive_regulation of Gene_expression of CD86 16 0.69 14.6 2.86
180 INT77602 Binding of VCAM1 8 0.41 8.66 2.86
181 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78
182 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76
183 INT97132 Negative_regulation of Positive_regulation of TBK1 5 0.08 6.54 2.76
184 INT106433 Regulation of CCR5 11 0.59 6.93 2.75
185 INT15745 Negative_regulation of GYPA 18 0.43 8.01 2.74
186 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
187 INT138882 Gene_expression of F11r 3 0.48 4.73 2.72
188 INT53443 Gene_expression of IKBKG 15 0.65 7.5 2.71
189 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7
190 INT289211 Localization of MFGE8 11 0.09 0.19 2.69
191 INT107968 Positive_regulation of NFKBIA 9 0.46 5.27 2.69
192 INT47974 Negative_regulation of Protein_catabolism of NFKBIA 7 0.49 2.38 2.69
193 INT56150 Localization of IL2RG 7 0.45 2.74 2.68
194 INT22739 Positive_regulation of DYNLL1 5 0.67 1.69 2.67
195 INT96273 Binding of TAP1 4 0.37 4.27 2.67
196 INT157461 Binding of CX3CR1 3 0.36 6.72 2.67
197 INT75685 Regulation of CD86 12 0.58 3.55 2.66
198 INT79938 Regulation of Gene_expression of VCAM1 12 0.61 11.22 2.64
199 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
200 INT15744 Localization of GYPA 12 0.64 7.19 2.61
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