GO:0044424

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Name intracellular part
Categary Component
Go Slim No
Go Link GO:0044424
Unique Molecular Interactions 483
Total Molecular Interactions 655
Total Single Events 6560
Pain Genes Associated 32

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intracellular part. They are ordered first by their pain relevance and then by number of times they were reported for intracellular part. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
3 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8
4 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
5 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
6 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
7 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
8 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
9 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
10 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
11 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
12 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
13 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
14 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
15 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
16 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
17 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
18 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
19 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
20 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
21 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
22 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
23 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
24 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
25 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
26 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
27 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
28 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
29 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
30 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
31 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
32 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
33 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
34 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
35 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
36 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
37 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
38 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
39 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
40 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
41 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
42 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
43 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
44 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
45 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
46 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
47 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
48 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
49 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
50 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
51 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
52 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
53 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
54 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
55 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
56 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
57 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
58 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
59 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
60 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
61 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
62 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
63 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
64 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
65 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
66 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
67 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
68 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
69 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
70 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
71 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
72 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
73 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
74 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
75 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
76 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
77 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
78 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
79 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
80 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3
81 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
82 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
83 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
84 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
85 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
86 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
87 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
88 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26
89 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
90 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25
91 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
92 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24
93 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
94 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
95 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
96 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
97 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
98 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
99 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
100 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
101 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19
102 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
103 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
104 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17
105 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
106 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14
107 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
108 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
109 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12
110 INT110522 Oprm1 Positive_regulation of Oprk1 1 0.11 0 1.12
111 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
112 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11
113 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
114 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
115 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
116 INT114007 Binding of Crygs and Oprm1 1 0.03 0 1.09
117 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
118 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
119 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
120 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
121 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
122 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02
123 INT106956 Oprm1 Positive_regulation of Positive_regulation of P9Ehs1 1 0.08 0.54 1.02
124 INT116751 Positive_regulation of Oprm1 Positive_regulation of Pik3cd 1 0.28 0.38 1.01
125 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
126 INT98002 Positive_regulation of Oprm1 Positive_regulation of P9Ehs1 1 0.10 0 1
127 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
128 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
129 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
130 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
131 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1
132 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1
133 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
134 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
135 INT169500 Negative_regulation of Mirlet7a-1 Regulation of Oprm1 1 0.37 0 0.99
136 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
137 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
138 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
139 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
140 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97
141 INT137919 Binding of Oprm1 and Stat3 1 0.30 0 0.97
142 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
143 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
144 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
145 INT146096 Positive_regulation of Binding of Oprm1 and Rgs9 1 0.44 0 0.94
146 INT65024 Binding of Oprm1 and Penk 1 0.03 0 0.93
147 INT79123 Binding of Pnoc and Oprm1 3 0.14 0 0.91
148 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9
149 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
150 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
151 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
152 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
153 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
154 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
155 INT112153 Regulation of Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.87
156 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86
157 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86
158 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
159 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
160 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
161 INT167947 Binding of STAT1 and Oprm1 1 0.00 0 0.86
162 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
163 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
164 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
165 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
166 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
167 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
168 INT167944 Binding of Oprm1 and Stat5a 1 0.00 0 0.85
169 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
170 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
171 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
172 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
173 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
174 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82
175 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81
176 INT112154 Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.81
177 INT6409 Binding of NFKBIL1 and Oprm1 1 0.00 0 0.8
178 INT106838 Lyar Regulation of Oprm1 1 0.04 0.28 0.8
179 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
180 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
181 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
182 INT141963 Binding of CALCRL and RAMP1 2 0.43 0.81 0.78
183 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
184 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78
185 INT55923 Penk Regulation of Transcription of Oprm1 1 0.26 0 0.78
186 INT55922 Penk Regulation of Oprm1 1 0.26 0 0.78
187 INT111888 Akt1 Regulation of Regulation of Oprm1 1 0.04 0 0.77
188 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77
189 INT121647 Binding of Oprm1 and Atrn 1 0.01 0.12 0.77
190 INT140312 Oprm1 Regulation of Gene_expression of Penk 1 0.07 0.26 0.77
191 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76
192 INT124404 Binding of POMC and Oprm1 1 0.00 0.25 0.75
193 INT144299 Il1b Positive_regulation of Oprm1 1 0.42 0.4 0.74
194 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
195 INT102086 TRNAI1 Negative_regulation of Positive_regulation of P2rx3 1 0.00 0.47 0.74
196 INT93710 Oprm1 Positive_regulation of Gene_expression of Calm3 1 0.25 0 0.73
197 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73
198 INT142507 Binding of Calca and Ramp1 1 0.31 0.48 0.73
199 INT76069 Binding of Oprl1 and Oprm1 1 0.07 0 0.73
200 INT145121 Msh3 Positive_regulation of Oprm1 1 0.06 0.15 0.72

Single Events

The table below shows the top 100 pain related interactions that have been reported for intracellular part. They are ordered first by their pain relevance and then by number of times they were reported in intracellular part. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
2 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
3 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
4 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
5 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
6 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
7 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
8 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
9 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
10 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
11 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
12 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
13 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
14 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
15 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
16 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
17 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
18 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
19 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
20 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
21 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
22 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
23 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
24 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
25 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
26 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
27 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
28 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
29 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
30 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
31 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
32 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
33 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
34 INT91285 Negative_regulation of P2rx2 29 0.57 12.74 15.48
35 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4
36 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38
37 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
38 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
39 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
40 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75
41 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51
42 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
43 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
44 INT102448 Gene_expression of RAMP1 23 0.75 4.62 10.9
45 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78
46 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
47 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
48 INT105304 Negative_regulation of Gene_expression of P2rx2 11 0.28 11.07 9.53
49 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47
50 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
51 INT20835 Negative_regulation of Negative_regulation of Oprm1 10 0.43 0.56 8.96
52 INT78578 Localization of P2rx3 21 0.78 9.55 8.86
53 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
54 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67
55 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
56 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
57 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85
58 INT62372 Positive_regulation of Localization of Oprm1 8 0.50 0.46 7.71
59 INT102080 Positive_regulation of P2rx3 20 0.67 6.91 7.3
60 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
61 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
62 INT62524 Negative_regulation of Phosphorylation of Oprm1 7 0.59 0.08 6.92
63 INT75228 Positive_regulation of Negative_regulation of Oprm1 8 0.49 0.95 6.9
64 INT78232 Binding of P2rx3 25 0.41 6.26 6.78
65 INT120261 Binding of P2rx2 19 0.28 5.8 6.72
66 INT87939 Gene_expression of P2RX3 23 0.75 6.15 6.62
67 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
68 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
69 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
70 INT47127 Gene_expression of BGN 11 0.75 17.09 6.25
71 INT120200 Binding of RAMP1 6 0.47 0.72 6.16
72 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
73 INT95475 Positive_regulation of P2RX3 13 0.67 6.28 5.82
74 INT112927 Negative_regulation of Localization of Oprm1 4 0.39 0.31 5.59
75 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
76 INT105306 Regulation of Gene_expression of P2rx2 7 0.21 6.92 5.22
77 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
78 INT148649 Transcription of P2rx2 8 0.43 8.11 4.79
79 INT109248 Gene_expression of Ramp1 8 0.72 2.45 4.69
80 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
81 INT91917 Negative_regulation of P2rx3 11 0.59 6.56 4.51
82 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
83 INT98357 Binding of Gnas 11 0.41 1.87 4.35
84 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
85 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
86 INT105998 Protein_catabolism of Oprm1 5 0.95 0.88 4.08
87 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
88 INT215163 Phosphorylation of P2rx2 19 0.60 1.43 3.62
89 INT109851 Negative_regulation of P2RX3 7 0.57 3.55 3.61
90 INT185148 Negative_regulation of BGN 3 0.20 1.23 3.56
91 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
92 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
93 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
94 INT8731 Regulation of Localization of Oprm1 3 0.43 0.25 3.4
95 INT68812 Regulation of Regulation of Oprm1 5 0.40 0.16 3.28
96 INT100188 Positive_regulation of Gene_expression of P2rx3 8 0.49 5.96 3.26
97 INT81830 Localization of P2rx2 14 0.73 5.42 3.16
98 INT167029 Regulation of Gene_expression of P2rx3 5 0.30 3.12 3.06
99 INT103049 Regulation of P2rx3 9 0.60 6 2.92
100 INT148934 Binding of Ramp1 4 0.36 0.94 2.89
101 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
102 INT91918 Localization of P2rx3 10 0.72 3.16 2.82
103 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78
104 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
105 INT142502 Gene_expression of Ramp1 5 0.67 2.23 2.72
106 INT47128 Regulation of BGN 2 0.41 0.33 2.62
107 INT145635 Phosphorylation of P2rx3 2 0.75 2.74 2.52
108 INT96803 Negative_regulation of Gene_expression of P2rx3 6 0.51 3.65 2.49
109 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
110 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
111 INT215496 Phosphorylation of P2rx3 10 0.44 1.88 2.41
112 INT87938 Regulation of P2RX3 5 0.43 2.37 2.32
113 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
114 INT71952 Regulation of Negative_regulation of Oprm1 3 0.43 0.09 2.18
115 INT82048 Positive_regulation of Neurod1 7 0.49 2.39 2.13
116 INT149755 Transcription of P2rx3 13 0.60 8.28 2.11
117 INT126910 Positive_regulation of Gene_expression of P2rx3 3 0.62 1.81 2.08
118 INT62522 Regulation of Phosphorylation of Oprm1 3 0.13 0 1.96
119 INT148648 Negative_regulation of Transcription of P2rx2 3 0.29 3.54 1.94
120 INT47129 Positive_regulation of BGN 4 0.46 2.29 1.93
121 INT194414 Positive_regulation of Gene_expression of RAMP1 4 0.60 0.57 1.89
122 INT92486 Positive_regulation of Gene_expression of P2RX3 5 0.49 1.56 1.82
123 INT62972 Gene_expression of Adcy5 3 0.67 0.23 1.72
124 INT58864 Regulation of Bgn 2 0.11 0.79 1.63
125 INT110041 Gene_expression of CHRM4 5 0.52 0.72 1.57
126 INT65602 Negative_regulation of Neurod1 7 0.42 2.52 1.55
127 INT130552 Negative_regulation of Localization of Oprm1 2 0.31 0.37 1.53
128 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
129 INT95478 Localization of P2RX3 5 0.73 1.73 1.49
130 INT13013 Positive_regulation of Adcy5 4 0.67 0.3 1.49
131 INT148933 Localization of Ramp1 1 0.77 0.75 1.48
132 INT112845 Negative_regulation of Binding of Nkx2-2 2 0.12 0.14 1.47
133 INT64371 Positive_regulation of Gene_expression of Neurod1 4 0.64 1.56 1.45
134 INT105997 Positive_regulation of Protein_catabolism of Oprm1 2 0.66 0.41 1.45
135 INT168726 Negative_regulation of Positive_regulation of P2rx2 1 0.07 0.09 1.44
136 INT21106 Regulation of Phosphorylation of Oprm1 3 0.61 0 1.43
137 INT132081 Regulation of Gene_expression of Nkx2-2 2 0.10 0.24 1.43
138 INT168727 Negative_regulation of Negative_regulation of P2rx2 1 0.07 0.09 1.43
139 INT166595 Positive_regulation of Binding of RAMP1 2 0.45 0.18 1.36
140 INT142815 Regulation of Regulation of P2rx2 4 0.33 0.69 1.33
141 INT85667 Negative_regulation of Negative_regulation of Oprm1 3 0.37 0.54 1.31
142 INT61429 Gene_expression of Adcy5 6 0.60 1.49 1.27
143 INT142503 Positive_regulation of Gene_expression of Ramp1 1 0.43 0.83 1.26
144 INT14138 Regulation of Localization of Oprm1 1 0.28 0 1.23
145 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
146 INT200838 Positive_regulation of Isl1 6 0.60 0.73 1.19
147 INT129374 Negative_regulation of Regulation of Oprm1 3 0.43 0.58 1.18
148 INT154813 Regulation of Transcription of P2rx2 2 0.26 2.38 1.17
149 INT161486 Regulation of Ramp1 2 0.61 1.64 1.16
150 INT110042 Binding of CHRM4 1 0.25 0.55 1.15
151 INT215493 Positive_regulation of Phosphorylation of P2rx3 2 0.33 1.27 1.14
152 INT114326 Phosphorylation of ADCY6 2 0.70 0.05 1.11
153 INT156718 Negative_regulation of Gene_expression of P2RX3 1 0.42 0.95 1.09
154 INT194413 Positive_regulation of RAMP1 1 0.36 0.07 1.08
155 INT215499 Positive_regulation of Phosphorylation of P2rx2 3 0.37 0.57 1.07
156 INT124810 Gene_expression of ADCY6 6 0.65 0 1.06
157 INT94210 Regulation of Neurod1 2 0.33 0.07 1.04
158 INT196743 Binding of Adcy5 1 0.25 0 1.04
159 INT49796 Positive_regulation of Binding of Adrb2 1 0.00 0 1.02
160 INT49795 Negative_regulation of Binding of Adrb2 1 0.00 0 1.02
161 INT95028 Gene_expression of Chrm4 8 0.39 2.66 0.99
162 INT21108 Negative_regulation of Phosphorylation of Oprm1 2 0.43 0 0.98
163 INT47130 Binding of BGN 3 0.33 0.33 0.97
164 INT223967 Regulation of Gene_expression of RAMP1 1 0.39 0.5 0.97
165 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96
166 INT149903 Localization of Cav3 3 0.80 1.1 0.93
167 INT93804 Gene_expression of Bgn 5 0.38 1.03 0.92
168 INT152491 Regulation of Transcription of P2rx3 2 0.27 0.87 0.91
169 INT60974 Gene_expression of Scgb1a1 34 0.71 7.48 0.9
170 INT119324 Positive_regulation of Gene_expression of Ramp1 3 0.53 0.94 0.89
171 INT307250 Negative_regulation of Gene_expression of P2rx3 3 0.40 0.71 0.87
172 INT116366 Binding of P2rx3 2 0.36 0.54 0.87
173 INT14976 Negative_regulation of Adrb2 3 0.24 0.75 0.86
174 INT42863 Regulation of Adrb2 1 0.11 1.02 0.85
175 INT42862 Regulation of Binding of Adrb2 1 0.15 1.03 0.85
176 INT173472 Positive_regulation of Isl1 1 0.03 0.2 0.83
177 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
178 INT196762 Negative_regulation of Adcy5 5 0.39 1.49 0.8
179 INT189249 Localization of BGN 2 0.08 2.14 0.8
180 INT123412 Negative_regulation of Transcription of Oprm1 2 0.56 0.06 0.79
181 INT33481 Positive_regulation of Gene_expression of Adrb2 2 0.48 0.38 0.78
182 INT124814 Localization of ADCY6 1 0.65 0 0.78
183 INT215783 Localization of Gnas 1 0.12 1.64 0.76
184 INT55921 Negative_regulation of Transcription of Oprm1 1 0.43 0 0.76
185 INT122072 Regulation of Binding of P2rx3 1 0.24 0.58 0.76
186 INT138396 Transcription of Nkx2-2 1 0.26 0.05 0.75
187 INT188159 Positive_regulation of Positive_regulation of P2rx3 1 0.20 0.74 0.75
188 INT138395 Positive_regulation of Transcription of Nkx2-2 1 0.19 0.05 0.75
189 INT196734 Positive_regulation of Adcy5 1 0.35 0 0.75
190 INT102082 Negative_regulation of Positive_regulation of P2rx3 1 0.41 0.47 0.74
191 INT62973 Positive_regulation of Gene_expression of Adcy5 1 0.05 0.16 0.74
192 INT124813 Negative_regulation of ADCY6 1 0.37 0 0.73
193 INT124811 Positive_regulation of Negative_regulation of ADCY6 1 0.40 0 0.73
194 INT31778 Negative_regulation of Adrb2 2 0.07 1.34 0.72
195 INT243779 Negative_regulation of Gene_expression of Isl1 2 0.30 2.62 0.68
196 INT129375 Negative_regulation of Regulation of Oprm1 1 0.28 0.49 0.68
197 INT131639 Positive_regulation of Binding of P2rx3 3 0.47 1.22 0.66
198 INT58867 Positive_regulation of Regulation of Bgn 1 0.20 0 0.65
199 INT35282 Positive_regulation of Chrm4 4 0.45 0.81 0.64
200 INT102081 Positive_regulation of Positive_regulation of P2rx3 1 0.49 0.31 0.64
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