GO:0044430

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Name cytoskeletal part
Categary Component
Go Slim No
Go Link GO:0044430
Unique Molecular Interactions 55
Total Molecular Interactions 82
Total Single Events 310
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytoskeletal part. They are ordered first by their pain relevance and then by number of times they were reported for cytoskeletal part. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
2 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1
3 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
4 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
5 INT246786 Ogg1 Regulation of Phosphorylation of Tsc2 1 0.20 0.42 0.04
6 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03
7 INT246791 Tsc2 Regulation of Ogg1 1 0.27 0.56 0.03
8 INT246784 Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1 1 0.20 0.43 0
9 INT246811 Ros1 Positive_regulation of Tsc2 1 0.02 0 0
10 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
11 INT246794 Ros1 Positive_regulation of Phosphorylation of Tsc2 1 0.03 0.66 0
12 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
13 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
14 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0
15 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
16 INT246787 Akt2 Positive_regulation of Phosphorylation of Tsc2 1 0.10 0.16 0
17 INT246789 Pik3c3 Regulation of Tsc2 1 0.02 0.34 0
18 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
19 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
20 INT246809 Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1 1 0.20 0.45 0
21 INT246801 Negative_regulation of Akt1 Negative_regulation of Phosphorylation of Tsc2 1 0.17 0 0
22 INT246792 Akt1 Positive_regulation of Phosphorylation of Tsc2 1 0.19 0.78 0
23 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0
24 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0
25 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0
26 INT246798 Akt1 Regulation of Tsc2 1 0.16 0.34 0
27 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
28 INT331224 Binding of Akt1 and Tsc2 1 0.03 0.33 0
29 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0
30 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0
31 INT246797 Tgfb1i1 Positive_regulation of Phosphorylation of Tsc2 1 0.01 0.66 0
32 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0
33 INT246912 Binding of Ifng and Igf2bp2 1 0.01 0.6 0
34 INT271984 Binding of Tsc2 and Skp2 1 0.06 0.34 0
35 INT272011 Binding of RAB5A and Tsc2 1 0.02 0.16 0
36 INT272004 Binding of Hspa1b and Tsc2 1 0.01 0.45 0
37 INT271983 Binding of Tsc2 and Rap1a 1 0.02 0.16 0
38 INT246806 Gene_expression of Akt1 Positive_regulation of Phosphorylation of Tsc2 1 0.19 0.32 0
39 INT286569 Binding of Pkd1 and Tsc2 1 0.06 1.01 0
40 INT246803 Binding of Akt1 and Tsc2 1 0.14 0.85 0
41 INT271989 Binding of Tsc2 and Psmd9 1 0.02 0.47 0
42 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0
43 INT246790 Gene_expression of Ros1 Positive_regulation of Phosphorylation of Tsc2 1 0.02 0 0
44 INT272007 Binding of Tsc2 and SCPEP1 1 0.27 0.46 0
45 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0
46 INT271987 Tsc2 Regulation of Skp2 1 0.10 0.28 0
47 INT246800 Binding of Tsc2 and Ogg1 1 0.16 0.38 0
48 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0
49 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytoskeletal part. They are ordered first by their pain relevance and then by number of times they were reported in cytoskeletal part. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT252054 Phosphorylation of TSC2 4 0.80 0.63 0.67
2 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
3 INT221833 Positive_regulation of TSC2 2 0.23 0.39 0.33
4 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26
5 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
6 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25
7 INT154360 Localization of Tsc2 1 0.56 0.16 0.22
8 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13
9 INT119228 Gene_expression of TSC2 3 0.75 4.43 0.13
10 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12
11 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12
12 INT271941 Binding of Tsc2 12 0.24 2.96 0.11
13 INT246772 Regulation of Phosphorylation of Tsc2 1 0.26 1.37 0.09
14 INT271938 Binding of Tsc1 1 0.43 3.18 0.07
15 INT246770 Positive_regulation of Negative_regulation of Tsc2 1 0.20 1.91 0.05
16 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04
17 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04
18 INT242338 Binding of TSC2 2 0.22 1.56 0.04
19 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04
20 INT246758 Gene_expression of Tsc1 1 0.11 0.55 0.04
21 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04
22 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03
23 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0
24 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0
25 INT228895 Binding of Tsc2 5 0.30 2.41 0
26 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0
27 INT246755 Regulation of Tsc2 4 0.50 1.01 0
28 INT216011 Regulation of TSC2 2 0.26 3.31 0
29 INT271921 Negative_regulation of Tsc2 2 0.26 1.19 0
30 INT271944 Negative_regulation of Phosphorylation of Tsc2 2 0.30 0.42 0
31 INT246761 Positive_regulation of Gene_expression of Tsc2 2 0.41 1.17 0
32 INT246777 Regulation of Gene_expression of Tsc2 1 0.19 0 0
33 INT246906 Gene_expression of Igf2bp2 1 0.26 0.8 0
34 INT246754 Negative_regulation of Binding of Tsc2 1 0.18 0.12 0
35 INT271905 Positive_regulation of Protein_catabolism of Tsc2 1 0.35 1.46 0
36 INT246748 Regulation of Tsc1 1 0.04 0.05 0
37 INT246747 Negative_regulation of Negative_regulation of Tsc2 1 0.18 0.56 0
38 INT271904 Localization of Tsc2 1 0.41 1.31 0
39 INT246908 Binding of Igf2bp2 1 0.15 1.96 0
40 INT246773 Phosphorylation of Tsc1 1 0.13 0.05 0
41 INT246780 Protein_catabolism of Tsc2 1 0.28 0.15 0
42 INT286549 Regulation of Tsc2 1 0.11 0.42 0
43 INT246752 Negative_regulation of Gene_expression of Tsc2 1 0.25 0.52 0
44 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0
45 INT271940 Protein_catabolism of Tsc2 1 0.50 0.7 0
46 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0
47 INT246759 Positive_regulation of Phosphorylation of Tsc2 1 0.29 9.31 0
48 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0
49 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0
50 INT276884 Regulation of Phosphorylation of TSC2 1 0.25 0.21 0
51 INT246751 Positive_regulation of Binding of Tsc2 1 0.21 0.15 0
52 INT331195 Positive_regulation of Negative_regulation of Tsc1 1 0.18 0.15 0
53 INT246903 Positive_regulation of Gene_expression of Igf2bp2 1 0.20 0.8 0
54 INT246757 Binding of Tsc1 1 0.06 0.19 0
55 INT271909 Positive_regulation of Tsc2 1 0.25 0.06 0
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