GO:0045019

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Name negative regulation of nitric oxide biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045019
Unique Molecular Interactions 1130
Total Molecular Interactions 1508
Total Single Events 12730
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of nitric oxide biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of nitric oxide biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
4 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
5 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
6 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
7 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
8 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
9 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
10 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
11 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
12 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
13 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
14 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
15 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
16 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
17 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
18 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
19 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
20 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
21 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
22 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
23 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
24 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
25 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
26 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
27 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
28 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
29 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
30 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
31 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
32 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
33 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
34 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
35 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
36 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
37 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
38 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
39 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
40 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
41 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
42 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
43 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
44 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
45 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
46 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
47 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
48 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
49 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
50 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
51 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
52 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
53 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
54 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
55 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
56 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
57 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
58 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
59 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
60 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
61 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
62 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
63 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
64 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
65 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
66 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
67 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
68 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
69 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
70 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
71 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
72 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
73 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
74 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
75 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
76 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
77 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
78 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
79 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
80 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
81 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49
82 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
83 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
84 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
85 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
86 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
87 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
88 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
89 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
90 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
91 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
92 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
93 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
94 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
95 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
96 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
97 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
98 INT128915 PENK Regulation of Gene_expression of OPRM1 1 0.22 0.07 1.43
99 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
100 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41
101 INT43814 Binding of Cpe and Oprm1 1 0.08 0 1.41
102 INT142852 Oprm1 Positive_regulation of Oprd1 1 0.41 0.06 1.41
103 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
104 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
105 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
106 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
107 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
108 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
109 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
110 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
111 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
112 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
113 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
114 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
115 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31
116 INT38624 Binding of Oprm1 and Insrr 2 0.01 0.24 1.31
117 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
118 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
119 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3
120 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
121 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
122 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
123 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
124 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
125 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
126 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
127 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
128 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26
129 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
130 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26
131 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
132 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
133 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25
134 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
135 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
136 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24
137 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
138 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
139 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
140 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
141 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
142 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
143 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
144 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
145 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
146 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
147 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
148 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
149 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
150 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
151 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
152 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
153 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
154 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
155 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
156 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
157 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19
158 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19
159 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
160 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
161 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
162 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
163 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
164 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17
165 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
166 INT137144 ITIH4 Regulation of OPRM1 1 0.20 1.13 1.16
167 INT125696 Binding of OPRM1 and SNRNP70 1 0.06 0.99 1.15
168 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14
169 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14
170 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13
171 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13
172 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12
173 INT110522 Oprm1 Positive_regulation of Oprk1 1 0.11 0 1.12
174 INT221183 Binding of OPRM1 and Mors1 1 0.00 0 1.12
175 INT59606 Binding of Tspo and Penk 1 0.04 0 1.12
176 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
177 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11
178 INT69338 Binding of Oprd1 and Oprm1 1 0.24 0.26 1.11
179 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
180 INT133497 Binding of Oprm1 and Cckbr 1 0.03 0 1.1
181 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
182 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1
183 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
184 INT142413 Oprm1 Positive_regulation of Gdnf 1 0.19 0.29 1.09
185 INT114007 Binding of Crygs and Oprm1 1 0.03 0 1.09
186 INT90145 Binding of OPRL1 and OPRM1 2 0.27 0.31 1.08
187 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
188 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
189 INT100678 IL4 Positive_regulation of STAT6 1 0.49 2.63 1.08
190 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
191 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
192 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
193 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
194 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
195 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
196 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04
197 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
198 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
199 INT150621 Binding of Oprm1 and Oprd1 1 0.00 0.08 1.02
200 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of nitric oxide biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of nitric oxide biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
2 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
3 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
4 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
5 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
6 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
7 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
8 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
9 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
10 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
11 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
12 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
13 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
14 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
15 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
16 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
17 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
18 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
19 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
20 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
21 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
22 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
23 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
24 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
25 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
26 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
27 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
28 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
29 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
30 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
31 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
32 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
33 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
34 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
35 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
36 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
37 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
38 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
39 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
40 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
41 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
42 INT90792 Localization of Il10 144 0.80 87.88 30.03
43 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
44 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
45 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
46 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
47 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34
48 INT74423 Localization of IL10 91 0.80 61.6 22.95
49 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
50 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
51 INT20379 Localization of Il4 85 0.73 51.22 20.55
52 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
53 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
54 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
55 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
56 INT74286 Regulation of Il10 42 0.44 28.06 19.44
57 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
58 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
59 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
60 INT72564 Localization of Il10 41 0.78 28.62 17.6
61 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
62 INT48892 Transcription of Il10 31 0.71 27.26 16.77
63 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73
64 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
65 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
66 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
67 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8
68 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69
69 INT80883 Positive_regulation of Phosphorylation of OPRM1 13 0.69 1.03 13.65
70 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
71 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15
72 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73
73 INT62523 Positive_regulation of Phosphorylation of Oprm1 11 0.53 0.75 12.51
74 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39
75 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39
76 INT69158 Localization of IL4 48 0.71 31.3 11.98
77 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
78 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42
79 INT79835 Regulation of Il10 28 0.61 21.22 11.29
80 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
81 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
82 INT71766 Transcription of Il10 31 0.69 24.66 10.78
83 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4
84 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37
85 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
86 INT18088 Binding of Tspo 26 0.48 9.12 10.2
87 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02
88 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87
89 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
90 INT73497 Regulation of IL10 33 0.45 22.6 9.19
91 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97
92 INT20835 Negative_regulation of Negative_regulation of Oprm1 10 0.43 0.56 8.96
93 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95
94 INT49884 Negative_regulation of Gene_expression of Il4 18 0.55 14.06 8.9
95 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
96 INT98835 Positive_regulation of Transcription of Oprm1 15 0.65 2.47 8.67
97 INT79693 Regulation of Il4 30 0.51 21.96 8.6
98 INT70303 Negative_regulation of Il4 19 0.52 12.9 8.54
99 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
100 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18
101 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05
102 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85
103 INT31060 Negative_regulation of Binding of OPRM1 12 0.37 2.65 7.75
104 INT101721 Positive_regulation of Transcription of OPRM1 8 0.48 1.22 7.74
105 INT62372 Positive_regulation of Localization of Oprm1 8 0.50 0.46 7.71
106 INT50040 Localization of Il4 15 0.67 8.26 7.69
107 INT6335 Binding of TSPO 39 0.44 10.88 7.66
108 INT103289 Binding of Il10 15 0.35 13.67 7.42
109 INT51741 Regulation of Gene_expression of Il4 23 0.36 12.7 7.39
110 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36
111 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06
112 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
113 INT62524 Negative_regulation of Phosphorylation of Oprm1 7 0.59 0.08 6.92
114 INT75228 Positive_regulation of Negative_regulation of Oprm1 8 0.49 0.95 6.9
115 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
116 INT60527 Transcription of IL10 16 0.56 13.57 6.42
117 INT42832 Negative_regulation of Positive_regulation of OPRM1 6 0.36 0.96 6.35
118 INT14258 Regulation of TSPO 32 0.60 10.16 6.24
119 INT97600 Regulation of Transcription of OPRM1 8 0.52 1.14 6.21
120 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14
121 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
122 INT58484 Regulation of Il4 12 0.45 8.67 6.09
123 INT67397 Transcription of Il4 15 0.54 11.36 6.06
124 INT27118 Regulation of Binding of OPRM1 10 0.62 1.18 5.97
125 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87
126 INT110545 Regulation of Regulation of OPRM1 7 0.42 1.68 5.67
127 INT112927 Negative_regulation of Localization of Oprm1 4 0.39 0.31 5.59
128 INT32979 Positive_regulation of Localization of OPRM1 5 0.50 0 5.54
129 INT56299 Transcription of IL4 15 0.64 10.2 5.44
130 INT77146 Binding of IL4 23 0.36 13.69 5.39
131 INT171562 Regulation of IL4 19 0.36 12.12 5.33
132 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26
133 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22
134 INT67228 Regulation of Gene_expression of Il4 11 0.50 6.67 5.2
135 INT16051 Regulation of Tspo 6 0.45 2.81 4.95
136 INT42833 Positive_regulation of Negative_regulation of OPRM1 6 0.48 0.12 4.95
137 INT142162 Binding of IL10 30 0.37 21.9 4.84
138 INT130290 Positive_regulation of Localization of IL10 16 0.47 9.38 4.75
139 INT71767 Positive_regulation of Transcription of Il10 10 0.67 5.55 4.66
140 INT29809 Gene_expression of Tspo 8 0.75 4.12 4.54
141 INT7841 Gene_expression of Tspo 10 0.75 7.63 4.45
142 INT6881 Binding of Tspo 12 0.46 5.03 4.38
143 INT56594 Positive_regulation of Localization of Il4 17 0.48 10.17 4.15
144 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14
145 INT105998 Protein_catabolism of Oprm1 5 0.95 0.88 4.08
146 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
147 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96
148 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
149 INT62497 Binding of Il4 7 0.26 4.19 3.88
150 INT194846 Positive_regulation of Positive_regulation of Il10 9 0.57 5.07 3.71
151 INT80882 Negative_regulation of Phosphorylation of OPRM1 4 0.45 0.21 3.68
152 INT92200 Negative_regulation of Localization of Il4 10 0.51 5.66 3.65
153 INT70919 Binding of Il4 19 0.36 6.58 3.59
154 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58
155 INT69155 Positive_regulation of Localization of IL4 13 0.40 10.18 3.56
156 INT74157 Negative_regulation of Positive_regulation of Il10 5 0.43 5.83 3.56
157 INT89521 Positive_regulation of Localization of Il10 8 0.44 6.45 3.51
158 INT118615 Negative_regulation of IL4 20 0.41 13.79 3.49
159 INT36716 Positive_regulation of Gene_expression of Tspo 4 0.68 3.48 3.49
160 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
161 INT97438 Transcription of Il4 17 0.67 9.17 3.4
162 INT8731 Regulation of Localization of Oprm1 3 0.43 0.25 3.4
163 INT194848 Negative_regulation of Localization of Il10 11 0.36 8.29 3.38
164 INT13347 Regulation of Negative_regulation of OPRM1 5 0.45 0.64 3.38
165 INT48893 Positive_regulation of Transcription of Il10 3 0.69 4.29 3.29
166 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28
167 INT68812 Regulation of Regulation of Oprm1 5 0.40 0.16 3.28
168 INT25745 Regulation of Tspo 6 0.45 0.25 3.1
169 INT115579 Positive_regulation of Positive_regulation of Il10 7 0.68 4.82 2.91
170 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78
171 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
172 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55
173 INT90791 Regulation of Localization of Il10 6 0.44 2.94 2.5
174 INT64062 Negative_regulation of Regulation of OPRM1 2 0.41 0.3 2.48
175 INT157049 Regulation of Localization of Il4 2 0.25 1.46 2.33
176 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
177 INT48894 Negative_regulation of Transcription of Il10 5 0.26 2.79 2.22
178 INT92119 Negative_regulation of Positive_regulation of Il4 3 0.14 1.88 2.2
179 INT71952 Regulation of Negative_regulation of Oprm1 3 0.43 0.09 2.18
180 INT127740 Regulation of Localization of Il10 3 0.60 0.65 2.18
181 INT74131 Positive_regulation of Tspo 7 0.50 0.92 2.11
182 INT32980 Positive_regulation of Regulation of OPRM1 2 0.45 0 1.98
183 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
184 INT62522 Regulation of Phosphorylation of Oprm1 3 0.13 0 1.96
185 INT160241 Negative_regulation of Positive_regulation of Il10 6 0.39 6.33 1.92
186 INT14257 Localization of TSPO 9 0.73 1.48 1.87
187 INT142684 Protein_catabolism of OPRM1 2 0.66 0.48 1.81
188 INT19576 Negative_regulation of Tspo 3 0.42 1.02 1.75
189 INT223746 Binding of Il10 12 0.36 9.49 1.73
190 INT76417 Positive_regulation of Positive_regulation of Il4 3 0.09 0.34 1.7
191 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
192 INT97434 Positive_regulation of Positive_regulation of Il4 8 0.40 3.51 1.66
193 INT174478 Negative_regulation of Localization of IL4 6 0.34 3.56 1.65
194 INT23609 Negative_regulation of Acp5 5 0.33 1.69 1.65
195 INT6391 Positive_regulation of Tspo 2 0.50 0.93 1.63
196 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
197 INT100694 Negative_regulation of Positive_regulation of IL4 5 0.34 3.27 1.58
198 INT184241 Regulation of Localization of Il4 4 0.15 3.89 1.58
199 INT130552 Negative_regulation of Localization of Oprm1 2 0.31 0.37 1.53
200 INT118400 Positive_regulation of Transcription of Il4 2 0.35 1.78 1.53
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