GO:0045022

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Name early endosome to late endosome transport
Categary Process
Go Slim No
Go Link GO:0045022
Unique Molecular Interactions 67
Total Molecular Interactions 117
Total Single Events 673
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for early endosome to late endosome transport. They are ordered first by their pain relevance and then by number of times they were reported for early endosome to late endosome transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
6 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
7 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
8 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
9 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
10 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
11 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
12 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
13 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
14 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
15 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
16 INT122427 Ighm Positive_regulation of Positive_regulation of P9Ehs1 1 0.00 0 0.56
17 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
18 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
19 INT79593 Binding of Reg1 and LMTK2 1 0.00 0.32 0.53
20 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
21 INT122426 Binding of Hint1 and Ighm 1 0.00 0 0.5
22 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
23 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
24 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
25 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23
26 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
27 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
28 INT260059 AKTIP Positive_regulation of TRPA1 1 0.02 0 0.15
29 INT351144 Binding of Ighg2b and Ighg2a 1 0.00 0.78 0.12
30 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1
31 INT208299 Binding of Hook3 and IGIP 1 0.03 0.37 0.08
32 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
33 INT332017 Binding of Ighm and Mbl1 1 0.11 0.26 0.06
34 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06
35 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
36 INT115324 Binding of FCGR3A and Ighm 1 0.00 0.56 0.05
37 INT115323 Binding of GPI and Ighm 1 0.00 0.56 0.05
38 INT315945 IgG Positive_regulation of Gene_expression of Ighm 1 0.13 0.56 0.04
39 INT290163 Atp6v1e1 Positive_regulation of Ighm 1 0.12 0.26 0.04
40 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
41 INT315943 Ighm Positive_regulation of Gene_expression of IgG 1 0.13 0.56 0.04
42 INT235544 Binding of Ighm and Olr1 1 0.00 0.68 0.03
43 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
44 INT307054 RHCE Regulation of AKTIP 1 0.00 0.6 0
45 INT215128 Ighm Regulation of Ighg1 1 0.12 0.27 0
46 INT338018 Binding of AR and Flna 1 0.11 0.33 0
47 INT215127 Ighg1 Regulation of Ighm 1 0.12 0.27 0
48 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0
49 INT290159 Atp6v1e1 Positive_regulation of Localization of Ighm 1 0.13 0.05 0
50 INT219252 Binding of Cd79a and Ighm 1 0.13 0 0
51 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
52 INT290154 Atp6v1e1 Positive_regulation of Gene_expression of Ighm 1 0.13 0.23 0
53 INT293231 AKTIP Regulation of DPH1 1 0.01 0 0
54 INT212524 Binding of Crp and Ighm 1 0.02 0.92 0
55 INT172011 IgG Regulation of Ighm 1 0.00 0.77 0
56 INT215133 Ighm Regulation of Gene_expression of Ctsd 1 0.25 0.26 0
57 INT255165 PM20D2 Regulation of FLNA 1 0.00 0.76 0
58 INT261893 Binding of Htt and Hap1 1 0.13 0.49 0
59 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
60 INT323332 Binding of Ighm and Chd7 1 0.02 0 0
61 INT323333 Binding of Ighm and Ict1 1 0.02 0 0
62 INT215132 Ighm Regulation of Ighg2b 1 0.11 0.27 0
63 INT255163 Binding of FLNA and PM20D2 1 0.00 0 0
64 INT215126 Ighm Regulation of Negative_regulation of Ctsd 1 0.15 0.27 0
65 INT324814 Binding of Ighm and Tlr9 1 0.06 0.17 0
66 INT236529 Binding of Om and Flna 1 0.00 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for early endosome to late endosome transport. They are ordered first by their pain relevance and then by number of times they were reported in early endosome to late endosome transport. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221172 Binding of Flna 32 0.42 1.37 51.59
2 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78
3 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
4 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
5 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
6 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47
7 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
8 INT39948 Binding of FLNA 45 0.42 58.05 4.27
9 INT221168 Localization of Flna 1 0.58 0.05 4.05
10 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
11 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65
12 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
13 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
14 INT46646 Localization of FLNA 19 0.73 18.83 2.53
15 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
16 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
17 INT221179 Regulation of Flna 1 0.24 0.13 2.04
18 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01
19 INT20207 Binding of Ighm 14 0.46 2.88 1.79
20 INT56100 Negative_regulation of Gene_expression of Ighm 5 0.48 2.07 1.72
21 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
22 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
23 INT122422 Negative_regulation of Phosphorylation of Ighm 1 0.01 0 0.91
24 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
25 INT192404 Localization of Ighm 15 0.48 5.8 0.85
26 INT122425 Phosphorylation of Ighm 1 0.01 0 0.85
27 INT254253 Transcription of Ighm 5 0.45 3.6 0.81
28 INT102655 Positive_regulation of Positive_regulation of Ighm 2 0.32 0.74 0.67
29 INT79584 Localization of LMTK2 1 0.01 0.51 0.61
30 INT79585 Negative_regulation of LMTK2 1 0.01 0.32 0.44
31 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
32 INT221178 Positive_regulation of Gene_expression of Flna 1 0.39 0 0.38
33 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
34 INT39350 Positive_regulation of Ighg2a 2 0.35 2.39 0.37
35 INT192406 Regulation of Ighm 16 0.31 5.58 0.29
36 INT79583 Gene_expression of LMTK2 1 0.01 0.15 0.27
37 INT79580 Regulation of Negative_regulation of LMTK2 1 0.01 0.14 0.25
38 INT79586 Regulation of LMTK2 1 0.01 0.33 0.24
39 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
40 INT317803 Negative_regulation of Ighg2a 1 0.02 0.71 0.15
41 INT317802 Regulation of Ighg2a 1 0.01 0.49 0.14
42 INT317804 Regulation of Gene_expression of Ighg2a 1 0.01 0.5 0.14
43 INT276623 Negative_regulation of Binding of Ighm 1 0.32 0.12 0.14
44 INT307059 Localization of AKTIP 1 0.01 0.48 0.14
45 INT317801 Gene_expression of Ighg2a 1 0.03 0.49 0.13
46 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
47 INT307060 Negative_regulation of AKTIP 6 0.01 2.79 0.08
48 INT208271 Binding of Hook3 1 0.03 0.36 0.08
49 INT305385 Negative_regulation of Localization of FLNA 1 0.16 0.79 0.08
50 INT346713 Positive_regulation of AKTIP 1 0.01 0.31 0.05
51 INT178278 Regulation of Positive_regulation of FLNA 1 0.04 0.4 0.05
52 INT236523 Binding of Flna 3 0.30 0.45 0.03
53 INT307057 Regulation of AKTIP 1 0.00 0.72 0.03
54 INT329837 Negative_regulation of Regulation of Ighm 1 0.13 0.12 0.03
55 INT254251 Negative_regulation of Positive_regulation of Ighm 3 0.24 0.8 0
56 INT276544 Gene_expression of Flna 3 0.63 1.97 0
57 INT192403 Positive_regulation of Localization of Ighm 2 0.23 0.08 0
58 INT276523 Negative_regulation of Gene_expression of Flna 2 0.48 0.8 0
59 INT307061 Gene_expression of AKTIP 1 0.01 0.21 0
60 INT192402 Positive_regulation of Regulation of Ighm 1 0.13 0 0
61 INT255171 Negative_regulation of Binding of FLNA 1 0.14 0.39 0
62 INT214620 Regulation of Localization of FLNA 1 0.02 0.46 0
63 INT195194 Regulation of Positive_regulation of Ighm 1 0.05 0.86 0
64 INT214621 Regulation of Gene_expression of FLNA 1 0.02 1.09 0
65 INT337958 Localization of Flna 1 0.61 0.43 0
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