GO:0045058

From wiki-pain
Jump to: navigation, search
Name T cell selection
Categary Process
Go Slim No
Go Link GO:0045058
Unique Molecular Interactions 231
Total Molecular Interactions 289
Total Single Events 3163
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T cell selection. They are ordered first by their pain relevance and then by number of times they were reported for T cell selection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
2 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
3 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
4 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
5 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
6 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
7 INT140921 Btnl2 Negative_regulation of Cd4 1 0.01 0.88 0.8
8 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
9 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
10 INT281129 Tcf21 Positive_regulation of Binding of Cd4 1 0.04 1.21 0.54
11 INT302834 Cd4 Positive_regulation of Gene_expression of Il7 1 0.05 1.02 0.54
12 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
13 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51
14 INT187100 Binding of Cd4 and Cd44 1 0.02 1.09 0.47
15 INT251297 Binding of C2 and CD4 1 0.04 0.35 0.47
16 INT187099 Binding of Cd4 and Itga1 1 0.00 1.09 0.46
17 INT208461 Binding of CD4 and IL16 1 0.05 3.04 0.41
18 INT139684 Binding of Cd4 and 2410016O06Rik 1 0.02 1.05 0.4
19 INT330515 TNFSF10 Regulation of Gene_expression of CD4 1 0.29 1.24 0.4
20 INT330518 TNFSF10 Regulation of CD4 1 0.29 1.24 0.4
21 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39
22 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37
23 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37
24 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37
25 INT226350 MBTPS1 Negative_regulation of Gene_expression of CD4 1 0.03 0.61 0.37
26 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37
27 INT281153 Binding of ITIH4 and Cd4 1 0.10 0.91 0.37
28 INT27030 HERPUD1 Regulation of CD4 1 0.41 0 0.34
29 INT188391 Binding of CD4 and HLA-DRB1 1 0.05 0.96 0.34
30 INT27037 HERPUD1 Regulation of Gene_expression of CD4 1 0.55 0 0.34
31 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33
32 INT211308 Binding of Cd4 and Cd8a 3 0.19 0.3 0.31
33 INT278693 ERAL1 Positive_regulation of CD4 1 0.05 1.1 0.31
34 INT278692 ERAL1 Positive_regulation of Positive_regulation of CD4 1 0.05 1.1 0.31
35 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29
36 INT174499 Binding of CD4 and HLA-E 1 0.04 1.08 0.29
37 INT349021 Binding of Cd8a and Cd4 1 0.10 0.58 0.26
38 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
39 INT330521 Binding of CD4 and TNFSF10 1 0.20 0.73 0.24
40 INT352081 Binding of CD4 and ADAM11 1 0.09 0.33 0.24
41 INT338430 Cd4 Negative_regulation of Gene_expression of Ik 1 0.01 1.27 0.22
42 INT339644 Il27 Regulation of Cd4 1 0.03 0.26 0.22
43 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21
44 INT238000 Cxcl10 Positive_regulation of Cd4 1 0.21 0.91 0.21
45 INT238002 Cxcl10 Positive_regulation of Positive_regulation of Cd4 1 0.21 0.91 0.21
46 INT226738 Binding of Cd4 and Prkca 1 0.02 0.52 0.2
47 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19
48 INT188570 Negative_regulation of IRF6 Positive_regulation of CD4 1 0.04 0.19 0.19
49 INT237196 LGALS4 Positive_regulation of Gene_expression of Cd4 1 0.21 0.96 0.19
50 INT188573 IRF6 Positive_regulation of CD4 1 0.05 0.19 0.19
51 INT226727 Positive_regulation of Prkca Positive_regulation of Protein_catabolism of Cd4 1 0.03 0.46 0.19
52 INT226761 Prkca Positive_regulation of Protein_catabolism of Cd4 1 0.03 0.45 0.19
53 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18
54 INT119561 TLE4 Negative_regulation of Positive_regulation of CD1D 1 0.00 0.68 0.16
55 INT119557 CD1D Positive_regulation of IL4 1 0.00 0.67 0.16
56 INT249707 Binding of Cd4 and GRDX 1 0.01 0.46 0.16
57 INT298056 Binding of IFN1@ and Cd4 1 0.31 1.07 0.16
58 INT188569 Binding of CD4 and TLR4 1 0.16 0.34 0.16
59 INT119558 CD1D Positive_regulation of TNF 1 0.00 0.67 0.15
60 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
61 INT119563 CD1D Positive_regulation of IL5 1 0.01 0.67 0.15
62 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
63 INT284213 Binding of Cd4 and Mela 1 0.06 0.6 0.14
64 INT284224 Binding of Cd4 and Hivan1 1 0.01 0.6 0.14
65 INT324128 Binding of Cd4 and Cd40 2 0.29 0.3 0.13
66 INT316059 Ps Regulation of Binding of Cd4 1 0.06 0.86 0.13
67 INT284214 Binding of Cd4 and Eclc 1 0.05 0.37 0.12
68 INT226752 Hivan1 Negative_regulation of Cd4 1 0.01 0.7 0.12
69 INT10731 NEUROD1 Regulation of CD4 1 0.42 1.3 0.12
70 INT10730 CD9 Regulation of CD4 1 0.42 1.3 0.12
71 INT181560 Binding of Cd4 and Cd86 1 0.32 0.38 0.12
72 INT251295 Binding of CD4 and Regulation of ITIH4 1 0.11 0.24 0.11
73 INT241748 CCR5 Regulation of CD4 1 0.21 0.39 0.11
74 INT188356 Binding of Cd28 and Positive_regulation of Localization of Cd4 1 0.30 0.18 0.11
75 INT189144 MTNR1B Positive_regulation of Gene_expression of CD4 1 0.01 0.35 0.11
76 INT274449 Binding of Cd4 and H2 2 0.05 1.25 0.1
77 INT333099 Localization of IL2 Negative_regulation of Negative_regulation of CD4 1 0.14 0.8 0.09
78 INT292632 CD4 Positive_regulation of Gene_expression of IL9 1 0.24 0 0.09
79 INT333094 HIVEP1 Regulation of CD4 1 0.00 0.22 0.09
80 INT274233 Negative_regulation of Binding of Cd4 and Fasl 1 0.13 0.91 0.08
81 INT333089 CD4 Positive_regulation of ERVW-1 1 0.05 0.07 0.08
82 INT274232 Binding of Cd4 and Fasl 1 0.11 0.9 0.08
83 INT342288 Binding of CD4 and HFE 1 0.01 1.26 0.08
84 INT15953 Binding of CD4 and IgG2a 1 0.54 0.38 0.08
85 INT228758 Rae1 Regulation of Cd4 1 0.12 0 0.08
86 INT183768 Csf2 Regulation of CD4 1 0.37 0.52 0.08
87 INT18916 Fam166a Positive_regulation of Cd4 1 0.02 0 0.07
88 INT226748 Cd4 Regulation of Vps28 1 0.08 0.35 0.07
89 INT237199 Binding of LGALS4 and Cd4 1 0.15 0.22 0.07
90 INT333096 Binding of CD4 and IFN1@ 1 0.12 0.17 0.07
91 INT284210 Binding of C2 and Cd4 1 0.03 0.32 0.07
92 INT226721 Binding of Cd4 and Vps28 1 0.06 0.35 0.07
93 INT333092 Binding of CD4 and IL2 1 0.01 0.17 0.07
94 INT226749 Cd4 Regulation of Protein_catabolism of Vps28 1 0.08 0.35 0.07
95 INT335715 Binding of FASLG and CD4 1 0.22 0.9 0.06
96 INT335714 Binding of FAS and CD4 1 0.38 0.9 0.06
97 INT331561 Binding of Cd4 and Cd40lg 1 0.28 0.06 0.06
98 INT333091 Localization of IFN1@ Negative_regulation of Negative_regulation of CD4 1 0.14 0.4 0.05
99 INT228733 Rae1 Negative_regulation of Gene_expression of Cd4 1 0.13 0.31 0.05
100 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05
101 INT228754 Hspa9 Negative_regulation of Gene_expression of Cd4 1 0.19 0.31 0.05
102 INT241751 Negative_regulation of Binding of CD4 and ITIH4 3 0.18 1.07 0.04
103 INT329102 Binding of CD4 and HLA-DQA2 2 0.04 0.92 0.04
104 INT185756 Binding of ITIH4 and Cd4 2 0.05 1.22 0.04
105 INT284212 Binding of Cd4 and Musd1 1 0.01 0.26 0.04
106 INT283464 Binding of CD4 and DLAT 1 0.07 0.69 0.04
107 INT284225 Binding of Cd4 and Ccr5 1 0.30 0.26 0.04
108 INT286968 Positive_regulation of STAT3 Regulation of Gene_expression of CD4 1 0.16 0.44 0.04
109 INT348816 Coro1a Positive_regulation of Positive_regulation of Cd4 1 0.16 0.42 0.04
110 INT248953 Il2ra Regulation of Gene_expression of Cd4 1 0.20 0 0.04
111 INT314967 Binding of Cd4 and Mthfd1 1 0.09 0.11 0.04
112 INT248945 Ctla4 Regulation of Gene_expression of Cd4 1 0.18 0 0.04
113 INT286962 IL2 Regulation of Gene_expression of CD4 1 0.01 0.45 0.04
114 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03
115 INT228229 Binding of Cd4 and Ntm 1 0.02 1.03 0.03
116 INT308540 CD4 Regulation of Localization of AGRP 1 0.39 0.85 0.03
117 INT281125 Binding of Ddc and Cd4 1 0.09 0.37 0.03
118 INT210592 Binding of Cd4 and Vcam1 1 0.01 0.65 0.03
119 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
120 INT327465 Binding of Cd4 and Neu1 1 0.06 0.73 0
121 INT326167 Binding of CD4 and Tmed8 1 0.47 0.29 0
122 INT260127 Binding of CD4 and Trav6-3 1 0.03 0 0
123 INT166237 NLRP1 Positive_regulation of Localization of CD1D 1 0.48 0 0
124 INT121649 Binding of CD4 and CXCL12 1 0.29 0.2 0
125 INT343501 CD4 Regulation of ERVW-1 1 0.09 0.16 0
126 INT331091 Tert Positive_regulation of Positive_regulation of Cd4 1 0.24 0.76 0
127 INT240420 Myo5a Positive_regulation of CD4 1 0.06 0.27 0
128 INT331565 Regulation of Binding of Cd4 and Apcs 1 0.12 0.08 0
129 INT355316 Binding of Cd4 and Cd5 1 0.03 1.99 0
130 INT277809 Binding of CD4 and CD40LG 1 0.15 0 0
131 INT226741 Mela Positive_regulation of Gene_expression of Cd4 1 0.02 1.01 0
132 INT350906 Twist1 Positive_regulation of Gene_expression of Cd4 1 0.10 1.49 0
133 INT329101 Binding of CD4 and INCENP 1 0.01 0.11 0
134 INT343499 CD4 Regulation of HIVEP1 1 0.02 0.16 0
135 INT226744 Hivan1 Regulation of Negative_regulation of Cd4 1 0.01 0.55 0
136 INT226755 Cxcr4 Negative_regulation of Cd4 1 0.15 0.38 0
137 INT342830 Binding of AGRP and Cd4 1 0.13 0.2 0
138 INT338765 Regulation of Binding of Cd4 and Tlr4 1 0.09 0.05 0
139 INT331563 Binding of Cd4 and Apcs 1 0.17 0.36 0
140 INT205121 Binding of CD4 and CD7 1 0.05 0.51 0
141 INT338768 Binding of Cd4 and Tlr4 1 0.08 0.05 0
142 INT226715 Binding of Cd4 and Tnip1 1 0.03 0.48 0
143 INT178206 Binding of Cd4 and Spna1 1 0.02 0.51 0
144 INT256385 Foxp3 Positive_regulation of Cd4 1 0.32 0.15 0
145 INT340516 CD4 Regulation of IL2 1 0.04 0.32 0
146 INT258911 Binding of CD4 and HLA-G 1 0.04 0.06 0
147 INT355315 Positive_regulation of Binding of Cd4 and Cd5 1 0.04 2 0
148 INT235494 SFTPA1 Positive_regulation of Positive_regulation of CD4 1 0.01 0 0
149 INT275190 Localization of CD4 Positive_regulation of Positive_regulation of LCK 1 0.10 0.99 0
150 INT256386 Il2ra Positive_regulation of Cd4 1 0.41 0.15 0
151 INT226713 Tsg101 Regulation of Protein_catabolism of Cd4 1 0.07 0.54 0
152 INT188750 Binding of CD4 and ADC 1 0.16 0.93 0
153 INT353129 Binding of CD4 and CXCR4 1 0.13 1.08 0
154 INT174502 HLA-B Regulation of CD4 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for T cell selection. They are ordered first by their pain relevance and then by number of times they were reported in T cell selection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
2 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
3 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
4 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
5 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
6 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75
7 INT36287 Binding of CD4 96 0.47 58.93 11.88
8 INT16404 Regulation of CD4 54 0.61 33.05 10.29
9 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51
10 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53
11 INT17049 Localization of CD4 57 0.75 35.33 6.89
12 INT160562 Localization of Cd4 49 0.71 27.58 6.78
13 INT50255 Regulation of Cd4 39 0.49 29.73 6.77
14 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61
15 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
16 INT53196 Binding of Cd4 44 0.47 27.28 5.85
17 INT95131 Binding of Cd4 27 0.37 21.62 5.07
18 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83
19 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
20 INT82444 Positive_regulation of Gene_expression of Cd4 10 0.47 4.36 3.12
21 INT243350 Binding of CD74 2 0.11 4.86 2.72
22 INT94628 Gene_expression of CD1D 12 0.75 5.58 2.13
23 INT17747 Regulation of Cd4 14 0.41 10.02 2.12
24 INT156720 Localization of CD1D 7 0.68 1.1 2.09
25 INT165213 Regulation of Gene_expression of Cd4 12 0.40 9.14 1.57
26 INT83328 Regulation of Gene_expression of Cd4 6 0.43 2.55 1.42
27 INT174486 Regulation of Gene_expression of CD4 12 0.36 6.09 1.39
28 INT53198 Positive_regulation of Positive_regulation of Cd4 6 0.49 3.75 1.36
29 INT58761 Regulation of CD1D 3 0.26 1.54 1.33
30 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09
31 INT82446 Negative_regulation of Positive_regulation of Cd4 3 0.39 1.79 1.09
32 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94
33 INT24860 Positive_regulation of CD1D 6 0.49 2.13 0.83
34 INT189171 Positive_regulation of Localization of CD4 7 0.49 5.88 0.79
35 INT14085 Localization of Cd4 3 0.44 1.22 0.79
36 INT98567 Negative_regulation of Gene_expression of Cd4 8 0.40 6.1 0.75
37 INT226631 Phosphorylation of Cd4 5 0.61 1.89 0.7
38 INT19218 Negative_regulation of Positive_regulation of CD4 9 0.41 9.21 0.69
39 INT202428 Positive_regulation of Binding of CD4 4 0.37 2.11 0.68
40 INT239024 Positive_regulation of Localization of Cd4 4 0.43 2.45 0.67
41 INT179130 Negative_regulation of Binding of Cd4 1 0.42 1.57 0.66
42 INT226698 Positive_regulation of Binding of Cd4 4 0.36 2.06 0.63
43 INT132104 Positive_regulation of Gene_expression of CD1D 2 0.03 0.55 0.57
44 INT202427 Negative_regulation of Localization of CD4 2 0.32 3.1 0.56
45 INT140070 Positive_regulation of Negative_regulation of Cd4 7 0.30 3.65 0.54
46 INT176649 Negative_regulation of Localization of Cd4 5 0.32 2.41 0.51
47 INT202426 Transcription of CD4 6 0.69 3.96 0.49
48 INT24859 Negative_regulation of CD1D 2 0.58 0.41 0.47
49 INT260119 Regulation of Localization of CD4 2 0.44 1.61 0.46
50 INT140071 Negative_regulation of Positive_regulation of Cd4 5 0.39 3.9 0.42
51 INT260118 Regulation of Regulation of CD4 1 0.44 1.66 0.4
52 INT353227 Positive_regulation of Regulation of Cd4 1 0.42 0.45 0.4
53 INT226641 Protein_catabolism of Cd4 1 0.53 6.12 0.4
54 INT62874 Gene_expression of CD74 1 0.00 0.64 0.37
55 INT109481 Regulation of Binding of Cd4 2 0.42 0.86 0.32
56 INT260110 Positive_regulation of Regulation of CD4 2 0.48 1.5 0.32
57 INT282775 Regulation of Positive_regulation of CD4 2 0.37 1.28 0.3
58 INT212592 Regulation of Binding of CD4 2 0.30 1.15 0.3
59 INT204183 Negative_regulation of Negative_regulation of CD4 3 0.30 1.79 0.22
60 INT193667 Regulation of Localization of Cd4 2 0.43 1.01 0.21
61 INT296064 Positive_regulation of Transcription of CD4 1 0.28 0.11 0.21
62 INT256517 Negative_regulation of Phosphorylation of Cd4 1 0.10 0.79 0.2
63 INT132107 Positive_regulation of Positive_regulation of CD1D 1 0.04 0.16 0.2
64 INT220836 Transcription of Cd4 4 0.61 3.62 0.19
65 INT245533 Regulation of Transcription of Cd4 1 0.20 1.02 0.15
66 INT226675 Negative_regulation of Protein_catabolism of Cd4 1 0.31 1.02 0.14
67 INT197034 Regulation of Localization of Cd4 1 0.26 0.6 0.14
68 INT20433 Regulation of Phosphorylation of CD4 1 0.06 0 0.13
69 INT20434 Phosphorylation of CD4 2 0.61 0 0.12
70 INT155154 Binding of CD1D 2 0.36 1.7 0.12
71 INT54314 Regulation of Regulation of Cd4 1 0.40 0.24 0.12
72 INT355870 Regulation of Positive_regulation of Cd4 1 0.27 0.59 0.12
73 INT203282 Negative_regulation of Binding of CD4 2 0.30 0.63 0.11
74 INT346124 Regulation of Binding of Cd4 1 0.25 0.22 0.07
75 INT247414 Positive_regulation of Positive_regulation of Cd4 2 0.42 1.23 0.04
76 INT219169 Positive_regulation of Localization of CD1D 1 0.22 0.65 0.03
77 INT226695 Positive_regulation of Phosphorylation of Cd4 1 0.37 0.23 0.03
78 INT194148 Positive_regulation of CD74 2 0.27 0.68 0
79 INT273759 Positive_regulation of Negative_regulation of CD4 2 0.45 2.05 0
80 INT337591 Transcription of Cd4 1 0.28 0 0
81 INT226622 Positive_regulation of Protein_catabolism of Cd4 1 0.37 3.13 0
82 INT346855 Positive_regulation of Binding of Cd4 1 0.36 0.68 0
83 INT226623 Negative_regulation of Negative_regulation of Cd4 1 0.23 0.42 0
84 INT208149 Regulation of Positive_regulation of Cd4 1 0.06 0.93 0
85 INT226660 Regulation of Negative_regulation of Cd4 1 0.15 0.49 0
86 INT85079 Positive_regulation of Negative_regulation of Cd4 1 0.13 0.17 0
87 INT336398 Negative_regulation of Gene_expression of CD1D 1 0.15 1 0
88 INT226629 Regulation of Protein_catabolism of Cd4 1 0.15 0.64 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox