GO:0045084

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Name positive regulation of interleukin-12 biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045084
Unique Molecular Interactions 828
Total Molecular Interactions 1195
Total Single Events 6342
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-12 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-12 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
6 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
7 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
8 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
9 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
10 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
11 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
12 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
13 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
14 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
15 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
16 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
17 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
18 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
19 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
20 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
21 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
22 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
23 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
24 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
25 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
26 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
27 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
28 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
29 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
30 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
31 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
32 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
33 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
34 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
35 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
36 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
37 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
38 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
39 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
40 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
41 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
42 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95
43 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
44 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
45 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
46 INT94501 Il2 Positive_regulation of Gene_expression of Ifng 1 0.03 1.63 0.92
47 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92
48 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
49 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
50 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
51 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
52 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
53 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
54 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
55 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
56 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
57 INT94331 IFNG Positive_regulation of CXCL10 4 0.11 1.31 0.82
58 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
59 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
60 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
61 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
62 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
63 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
64 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
65 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
66 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
67 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72
68 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
69 INT151679 Ifng Negative_regulation of Oas1b 1 0.12 1.24 0.71
70 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
71 INT151676 Ifng Negative_regulation of Art2a-ps 1 0.00 1.25 0.71
72 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
73 INT195545 Rel Regulation of Gene_expression of Grm3 1 0.01 0.46 0.71
74 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
75 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
76 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
77 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
78 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
79 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
80 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
81 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
82 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
83 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
84 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
85 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64
86 INT56235 Ifng Positive_regulation of Gene_expression of RT1-EC2 1 0.23 0.33 0.62
87 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
88 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
89 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
90 INT154533 Ifng Negative_regulation of Il4 1 0.11 0.62 0.6
91 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
92 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
93 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
94 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
95 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
96 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
97 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58
98 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
99 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
100 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
101 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
102 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
103 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
104 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
105 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
106 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
107 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
108 INT137162 IFNG Positive_regulation of Gene_expression of CXCL9 1 0.45 0.62 0.54
109 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
110 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
111 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
112 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
113 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
114 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
115 INT138928 Ifng Positive_regulation of Transcription of Cxcl9 1 0.31 0.65 0.51
116 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
117 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
118 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
119 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51
120 INT120852 PRL Positive_regulation of IRF1 1 0.44 0.99 0.51
121 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5
122 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
123 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
124 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
125 INT120854 IRF1 Positive_regulation of Localization of TNF 1 0.20 0.94 0.49
126 INT138927 Ifng Positive_regulation of Gene_expression of Stat1 1 0.29 0.7 0.49
127 INT142155 Ifng Positive_regulation of Il5 1 0.08 0 0.48
128 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
129 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
130 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
131 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
132 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
133 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
134 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
135 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
136 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
137 INT99790 Ifng Positive_regulation of Cxcr2 1 0.12 0.28 0.46
138 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
139 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
140 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
141 INT256356 Binding of Nfkb1 and Rela 1 0.21 0 0.44
142 INT126337 Pax3 Positive_regulation of Gene_expression of Ifng 1 0.05 0.56 0.44
143 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44
144 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
145 INT126340 Pax3 Regulation of Gene_expression of Ifng 1 0.03 0.56 0.44
146 INT126338 Insrr Regulation of Gene_expression of Ifng 1 0.00 0.56 0.43
147 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43
148 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
149 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42
150 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
151 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
152 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
153 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
154 INT17305 Ifng Positive_regulation of RT1-CE1 1 0.06 0.46 0.41
155 INT17308 Ifng Positive_regulation of Atp8a1 1 0.64 0.45 0.41
156 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
157 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
158 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
159 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
160 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
161 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
162 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
163 INT141016 Il18 Positive_regulation of Gene_expression of Ifng 1 0.39 0.27 0.39
164 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
165 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
166 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
167 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
168 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
169 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
170 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
171 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
172 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
173 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
174 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
175 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
176 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
177 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
178 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
179 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
180 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
181 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37
182 INT152361 Binding of Ifng and T2dm2 1 0.00 0.86 0.37
183 INT140569 Ifng Positive_regulation of Gene_expression of Il6 1 0.00 0.82 0.36
184 INT140571 Ifng Positive_regulation of Ifnb1 1 0.01 0.82 0.36
185 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
186 INT88192 IFNG Regulation of Gene_expression of ZAK 1 0.01 0.75 0.36
187 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
188 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
189 INT152315 Ifng Regulation of Ednrb 1 0.19 0.22 0.36
190 INT140572 Ifng Positive_regulation of Gene_expression of Ifnb1 1 0.01 0.82 0.36
191 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
192 INT140573 Positive_regulation of Ifng Positive_regulation of Ifnb1 1 0.01 0.83 0.36
193 INT152316 Ifng Regulation of Edn1 1 0.01 0.22 0.35
194 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
195 INT144045 IFNG Negative_regulation of Gene_expression of PTGES 1 0.63 0.47 0.35
196 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
197 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
198 INT189492 Ifng Positive_regulation of Localization of Darc 1 0.00 0.53 0.34
199 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
200 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-12 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-12 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
3 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
4 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
5 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
6 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
7 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
8 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
9 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
10 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
11 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
12 INT8518 Localization of Ifng 53 0.81 36.68 24.13
13 INT134651 Binding of TLR4 89 0.48 66.96 23.19
14 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
15 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
16 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
17 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
18 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
19 INT19509 Localization of Ifng 55 0.78 28.25 18.67
20 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
21 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
22 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
23 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
24 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
25 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
26 INT93482 Localization of Rela 56 0.78 24.52 14.82
27 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
28 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
29 INT4931 Localization of IFNG 53 0.78 33.25 13.65
30 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
31 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
32 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
33 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
34 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
35 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
36 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
37 INT66213 Localization of RELA 63 0.78 14.71 8.77
38 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
39 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
40 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
41 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
42 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
43 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
44 INT74154 Transcription of Ifng 14 0.67 10.33 6.21
45 INT97797 Localization of TLR4 18 0.77 13.78 6
46 INT15803 Regulation of IFNG 21 0.44 12.57 5.98
47 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
48 INT5186 Regulation of Ifng 11 0.45 8.78 5.9
49 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
50 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
51 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
52 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
53 INT62132 Regulation of Gene_expression of Ifng 12 0.62 1.28 4.77
54 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
55 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
56 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
57 INT118583 Positive_regulation of IRF1 10 0.68 3.75 3.91
58 INT34054 Regulation of Gene_expression of IFNG 8 0.42 3.69 3.76
59 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
60 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
61 INT195527 Binding of Rela 17 0.25 4.42 3.56
62 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
63 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
64 INT87027 Positive_regulation of Localization of IFNG 12 0.67 5.78 3.35
65 INT133557 Transcription of Rela 6 0.52 3.86 3.2
66 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
67 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
68 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
69 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
70 INT99129 Negative_regulation of LTB 5 0.57 0.7 2.84
71 INT67078 Binding of Ifng 7 0.48 4.84 2.73
72 INT195531 Gene_expression of Rel 9 0.75 5.02 2.72
73 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
74 INT15197 Regulation of Gene_expression of Ifng 8 0.34 2.66 2.69
75 INT111145 Negative_regulation of Positive_regulation of Ifng 7 0.41 2.21 2.61
76 INT91669 Negative_regulation of Localization of IFNG 5 0.57 4.1 2.58
77 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
78 INT16964 Binding of IFNG 27 0.48 14.31 2.45
79 INT141195 Negative_regulation of Rela 14 0.29 8.61 2.44
80 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41
81 INT73980 Transcription of Ifng 12 0.72 5.42 2.4
82 INT70918 Positive_regulation of Localization of Ifng 5 0.45 2.79 2.33
83 INT67437 Negative_regulation of Localization of Ifng 7 0.47 2.23 2.28
84 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18
85 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06
86 INT111530 Positive_regulation of Regulation of Ifng 1 0.41 0.32 2.01
87 INT118884 Gene_expression of IRF1 5 0.66 2.71 2
88 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
89 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
90 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
91 INT118882 Positive_regulation of Gene_expression of IRF1 1 0.49 1.35 1.92
92 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89
93 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
94 INT144649 Negative_regulation of Positive_regulation of Rela 11 0.26 8.27 1.87
95 INT61627 Transcription of IFNG 6 0.69 4.28 1.83
96 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
97 INT55169 Binding of RELA 40 0.36 4.91 1.74
98 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
99 INT108875 Positive_regulation of Localization of RELA 9 0.49 1.43 1.72
100 INT69675 Positive_regulation of Rel 5 0.32 1.69 1.7
101 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
102 INT256341 Positive_regulation of Phosphorylation of Rela 5 0.46 2.12 1.62
103 INT113716 Positive_regulation of Transcription of Ifng 1 0.53 2.56 1.61
104 INT56228 Positive_regulation of Positive_regulation of Ifng 2 0.43 2.83 1.4
105 INT69676 Binding of Rel 4 0.47 0.16 1.38
106 INT133552 Negative_regulation of Transcription of Rela 2 0.23 2.43 1.34
107 INT110252 Positive_regulation of Gene_expression of RELA 29 0.49 6.36 1.31
108 INT153220 Negative_regulation of Positive_regulation of Rela 1 0.09 0.31 1.31
109 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
110 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26
111 INT19923 Regulation of Localization of Ifng 3 0.22 1.1 1.25
112 INT109243 Regulation of Positive_regulation of IFNG 1 0.45 1.27 1.23
113 INT202476 Positive_regulation of Gene_expression of Rela 10 0.34 3.65 1.22
114 INT99131 Regulation of LTB 1 0.26 0 1.22
115 INT298979 Gene_expression of Traf6 5 0.31 1.75 1.21
116 INT111536 Positive_regulation of Negative_regulation of Ifng 1 0.41 0.35 1.18
117 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
118 INT33475 Gene_expression of Ltb 4 0.58 2.45 1.09
119 INT122884 Positive_regulation of Transcription of Ifng 1 0.39 1.08 1.03
120 INT118738 Transcription of Tlr4 4 0.70 1.39 1
121 INT158375 Positive_regulation of Transcription of Rela 2 0.45 0.8 0.94
122 INT248678 Gene_expression of Rela 4 0.16 2.35 0.9
123 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
124 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
125 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
126 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
127 INT103303 Negative_regulation of Transcription of Ifng 6 0.43 2.7 0.83
128 INT43488 Regulation of Positive_regulation of Ifng 1 0.42 0.71 0.83
129 INT104033 Gene_expression of LTB 4 0.75 3.06 0.81
130 INT64635 Binding of Ifng 2 0.36 0.57 0.81
131 INT10017 Gene_expression of REL 8 0.65 2.01 0.78
132 INT256349 Regulation of Phosphorylation of Rela 3 0.31 0.26 0.77
133 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
134 INT11138 Regulation of Localization of Ifng 2 0.56 0.8 0.77
135 INT55174 Binding of REL 4 0.25 2.15 0.76
136 INT73240 Negative_regulation of Transcription of IFNG 1 0.41 0.92 0.76
137 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
138 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
139 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
140 INT69677 Negative_regulation of Binding of Rel 2 0.41 0.17 0.71
141 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
142 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
143 INT116009 Regulation of Negative_regulation of Ifng 1 0.44 0.09 0.67
144 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
145 INT186266 Gene_expression of Irf1 4 0.36 3.26 0.64
146 INT61622 Positive_regulation of Transcription of IFNG 1 0.26 0.29 0.63
147 INT188799 Positive_regulation of Protein_catabolism of Traf6 2 0.19 1.98 0.62
148 INT56231 Regulation of Positive_regulation of Ifng 1 0.39 0.33 0.62
149 INT108874 Regulation of Localization of RELA 5 0.44 1.09 0.61
150 INT194899 Positive_regulation of Negative_regulation of Rela 1 0.26 2.07 0.61
151 INT99130 Regulation of Regulation of LTB 1 0.26 0 0.61
152 INT178715 Localization of Rela 1 0.11 0.86 0.59
153 INT184028 Protein_catabolism of Rela 4 0.40 2.12 0.57
154 INT116045 Negative_regulation of Positive_regulation of Ifng 2 0.03 2.5 0.57
155 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
156 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
157 INT140905 Localization of Rel 5 0.73 2.26 0.5
158 INT61109 Negative_regulation of Positive_regulation of IFNG 1 0.53 0.57 0.5
159 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
160 INT73559 Negative_regulation of Positive_regulation of RELA 2 0.36 1.37 0.49
161 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
162 INT158263 Negative_regulation of Gene_expression of Ltb 2 0.29 1.2 0.47
163 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
164 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
165 INT15715 Positive_regulation of LTB 2 0.67 1.4 0.45
166 INT188800 Protein_catabolism of Traf6 2 0.40 1.6 0.45
167 INT15717 Negative_regulation of Positive_regulation of LTB 1 0.02 0.6 0.45
168 INT123721 Negative_regulation of Negative_regulation of Ifng 1 0.34 0.26 0.45
169 INT47979 Localization of REL 1 0.78 0.63 0.42
170 INT47975 Negative_regulation of Localization of REL 1 0.57 0.64 0.42
171 INT29293 Positive_regulation of Ltb 2 0.14 0.66 0.41
172 INT158947 Positive_regulation of Gene_expression of Ltb 1 0.47 1.38 0.41
173 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
174 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
175 INT69684 Negative_regulation of Rel 2 0.42 0.99 0.37
176 INT174684 Gene_expression of Tlr6 2 0.44 2.62 0.36
177 INT217464 Binding of Traf6 5 0.29 1.28 0.35
178 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
179 INT349651 Positive_regulation of Gene_expression of Rela 1 0.03 1.46 0.33
180 INT73555 Negative_regulation of RELA 5 0.41 0.57 0.32
181 INT203075 Positive_regulation of Traf6 1 0.16 0.67 0.32
182 INT203074 Positive_regulation of Positive_regulation of Traf6 1 0.16 0.67 0.32
183 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
184 INT249110 Positive_regulation of Binding of REL 1 0.19 1 0.31
185 INT140903 Negative_regulation of Localization of Rel 1 0.03 0.9 0.3
186 INT9156 Negative_regulation of Regulation of Ifng 1 0.19 0.94 0.3
187 INT129297 Positive_regulation of Phosphorylation of RELA 1 0.24 0.33 0.29
188 INT273623 Regulation of Rela 7 0.14 4 0.28
189 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
190 INT319704 Negative_regulation of Binding of Rela 1 0.05 0.51 0.26
191 INT170600 Negative_regulation of Gene_expression of RELA 16 0.39 1.29 0.25
192 INT170596 Regulation of RELA 4 0.41 0.39 0.25
193 INT162519 Regulation of Localization of Rela 3 0.20 1.78 0.25
194 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
195 INT146953 Negative_regulation of Positive_regulation of Rel 1 0.01 1 0.25
196 INT69686 Positive_regulation of Binding of Rel 1 0.49 0 0.24
197 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
198 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
199 INT170594 Regulation of Gene_expression of RELA 6 0.41 0.15 0.22
200 INT210927 Positive_regulation of Traf6 4 0.32 0.99 0.22
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