GO:0045085

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Name negative regulation of interleukin-2 biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045085
Unique Molecular Interactions 26
Total Molecular Interactions 33
Total Single Events 443
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of interleukin-2 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of interleukin-2 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59
2 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
3 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
4 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37
5 INT316676 Binding of CRX and SFTPD 1 0.05 0.65 0.33
6 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
7 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19
8 INT236307 SFTPD Positive_regulation of IGKV2D-38 1 0.03 0.57 0.18
9 INT296081 Binding of FOXP3 and Gtf3a 1 0.00 1.16 0.16
10 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16
11 INT296082 Binding of Rel and FOXP3 1 0.35 1.14 0.15
12 INT296029 Binding of HLA-DQA2 and LAG3 1 0.02 0.43 0.12
13 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
14 INT296039 Binding of FOXP3 and IL17RB 1 0.01 0.63 0.08
15 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
16 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07
17 INT286967 Positive_regulation of STAT3 Regulation of Gene_expression of FOXP3 1 0.35 0.44 0.04
18 INT350704 Foxp3 Negative_regulation of Gene_expression of Mir142 1 0.02 0.13 0.04
19 INT350696 Mir31 Regulation of Gene_expression of Foxp3 1 0.04 0 0.03
20 INT350707 Uts2r Negative_regulation of Gene_expression of Foxp3 1 0.03 0 0
21 INT256385 Foxp3 Positive_regulation of Cd4 1 0.32 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of interleukin-2 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of interleukin-2 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
2 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
3 INT236335 Gene_expression of SFTPD 26 0.75 15.92 4.59
4 INT162372 Positive_regulation of SFTPD 15 0.67 11.8 3.21
5 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
6 INT105694 Binding of SFTPD 11 0.46 8.47 2.45
7 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
8 INT245577 Localization of SFTPD 7 0.63 10.43 1.84
9 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
10 INT212048 Negative_regulation of SFTPD 3 0.42 5.45 1.61
11 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46
12 INT229562 Negative_regulation of Foxp3 6 0.36 3.7 1.14
13 INT236328 Regulation of SFTPD 6 0.38 3.04 0.85
14 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83
15 INT157492 Transcription of Foxp3 4 0.61 1.69 0.81
16 INT150251 Transcription of FOXP3 7 0.61 0.43 0.76
17 INT221428 Negative_regulation of Negative_regulation of FOXP3 1 0.35 1.97 0.7
18 INT306800 Positive_regulation of Localization of SFTPD 1 0.16 2.1 0.68
19 INT236330 Regulation of Gene_expression of SFTPD 2 0.59 1.55 0.65
20 INT297286 Positive_regulation of Foxp3 7 0.58 3.05 0.63
21 INT157490 Regulation of Gene_expression of Foxp3 5 0.37 2.4 0.47
22 INT188345 Regulation of Foxp3 3 0.18 1.59 0.42
23 INT260115 Regulation of FOXP3 3 0.29 0.75 0.34
24 INT316678 Regulation of Positive_regulation of SFTPD 1 0.38 0.96 0.34
25 INT236323 Positive_regulation of Transcription of SFTPD 1 0.12 0.47 0.32
26 INT236324 Transcription of SFTPD 1 0.17 0.47 0.32
27 INT236327 Positive_regulation of Gene_expression of SFTPD 1 0.12 0.47 0.32
28 INT253424 Protein_catabolism of SFTPD 2 0.74 1.12 0.31
29 INT260120 Regulation of Gene_expression of FOXP3 4 0.31 2.74 0.29
30 INT206700 Binding of LAG3 1 0.23 0.7 0.21
31 INT188346 Binding of Foxp3 1 0.27 0.4 0.18
32 INT276372 Negative_regulation of Gene_expression of FOXP3 2 0.38 1.49 0.16
33 INT150253 Positive_regulation of Transcription of FOXP3 2 0.39 0 0.15
34 INT335788 Localization of FOXP3 1 0.34 0.42 0.15
35 INT335812 Regulation of Transcription of FOXP3 1 0.21 0.34 0.14
36 INT286970 Binding of FOXP3 1 0.24 1.04 0.13
37 INT296063 Gene_expression of LAG3 1 0.16 0.46 0.12
38 INT276923 Localization of Foxp3 1 0.38 0.52 0.12
39 INT286971 Positive_regulation of Positive_regulation of FOXP3 1 0.32 0.57 0.09
40 INT296074 Regulation of Positive_regulation of FOXP3 1 0.18 0.28 0.06
41 INT236333 Positive_regulation of Regulation of SFTPD 1 0.12 0.09 0.04
42 INT260113 Positive_regulation of Regulation of FOXP3 1 0.32 0.15 0.04
43 INT333755 Negative_regulation of Positive_regulation of Foxp3 1 0.49 0.18 0.03
44 INT157493 Positive_regulation of Transcription of Foxp3 1 0.59 0.06 0
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