GO:0045089

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Name positive regulation of innate immune response
Categary Process
Go Slim No
Go Link GO:0045089
Unique Molecular Interactions 63
Total Molecular Interactions 98
Total Single Events 606
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of innate immune response. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of innate immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
2 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
3 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
4 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
5 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
6 INT144449 Plscr1 Positive_regulation of Gene_expression of Nqo1 1 0.15 0.18 0.8
7 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
8 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
9 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
10 INT12052 Xcl1 Negative_regulation of Rnpep 1 0.01 0 0.71
11 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
12 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
13 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
14 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
15 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
16 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35
17 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
18 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
19 INT246435 Xcl1 Positive_regulation of Gene_expression of Cd79a 1 0.07 0.83 0.27
20 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
21 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
22 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
23 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
24 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
25 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
26 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
27 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
28 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
29 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
30 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
31 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
32 INT107425 Binding of ST3GAL4 and IFNK 1 0.08 1.12 0.17
33 INT254214 Binding of Myd88 and Tirap 1 0.15 0.55 0.17
34 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
35 INT119561 TLE4 Negative_regulation of Positive_regulation of CD1D 1 0.00 0.68 0.16
36 INT119557 CD1D Positive_regulation of IL4 1 0.00 0.67 0.16
37 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
38 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 0.27 1.28 0.16
39 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
40 INT119558 CD1D Positive_regulation of TNF 1 0.00 0.67 0.15
41 INT119563 CD1D Positive_regulation of IL5 1 0.01 0.67 0.15
42 INT43495 Cd74 Regulation of Gene_expression of Ifng 1 0.47 0 0.14
43 INT298052 Binding of Cd74 and Vip 1 0.00 1.05 0.13
44 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13
45 INT171295 CXCL10 Positive_regulation of CCL5 1 0.04 0.06 0.12
46 INT49283 Binding of IGLL1 and IFNK 1 0.02 0.9 0.1
47 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
48 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07
49 INT350482 Tirap Regulation of TICAM2 1 0.05 0.06 0.06
50 INT350478 Tirap Regulation of Ticam1 1 0.07 0.06 0.05
51 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04
52 INT171279 IL6 Positive_regulation of CCL5 1 0.04 0.38 0.04
53 INT348820 Cd74 Regulation of Gene_expression of TFDP3 1 0.07 0.16 0.04
54 INT171301 TNF Positive_regulation of CCL5 1 0.16 0.38 0.04
55 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0
56 INT166237 NLRP1 Positive_regulation of Localization of CD1D 1 0.48 0 0
57 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0
58 INT171282 TNFSF12 Positive_regulation of Gene_expression of CCL5 1 0.01 0 0
59 INT307307 COMP Positive_regulation of EREG 1 0.01 0.46 0
60 INT307309 Binding of CALR and EREG 1 0.00 0.83 0
61 INT327099 Binding of EGF and EREG 1 0.05 0.35 0
62 INT307308 Binding of COMP and EREG 1 0.01 0.41 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of innate immune response. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of innate immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
2 INT78901 Localization of CCL5 67 0.78 40.79 20.59
3 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
4 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
5 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
6 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
7 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
8 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
9 INT187168 Binding of Cd74 13 0.27 11.2 3.44
10 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
11 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
12 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
13 INT194661 Binding of CCL5 9 0.46 6.07 2.73
14 INT94628 Gene_expression of CD1D 12 0.75 5.58 2.13
15 INT156720 Localization of CD1D 7 0.68 1.1 2.09
16 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
17 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
18 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
19 INT114270 Gene_expression of Plscr1 6 0.47 1.33 1.49
20 INT58761 Regulation of CD1D 3 0.26 1.54 1.33
21 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
22 INT123948 Positive_regulation of Plscr1 4 0.42 1.02 0.93
23 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
24 INT114275 Regulation of Gene_expression of Plscr1 2 0.24 0.51 0.85
25 INT24860 Positive_regulation of CD1D 6 0.49 2.13 0.83
26 INT174420 Positive_regulation of Gene_expression of Cd74 3 0.20 1.92 0.81
27 INT89340 Positive_regulation of EREG 5 0.69 4.98 0.77
28 INT322032 Binding of TLR8 3 0.32 2.57 0.69
29 INT132104 Positive_regulation of Gene_expression of CD1D 2 0.03 0.55 0.57
30 INT284454 Binding of Tirap 4 0.26 2.07 0.49
31 INT24859 Negative_regulation of CD1D 2 0.58 0.41 0.47
32 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
33 INT174418 Regulation of Gene_expression of Cd74 1 0.04 0.9 0.46
34 INT254172 Negative_regulation of Gene_expression of Cd74 1 0.24 1.03 0.44
35 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
36 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
37 INT89341 Gene_expression of EREG 3 0.78 2.38 0.38
38 INT89342 Transcription of EREG 1 0.69 1.22 0.35
39 INT49286 Binding of IFNK 2 0.25 2.48 0.34
40 INT207897 Positive_regulation of TLR8 3 0.17 2.52 0.33
41 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
42 INT89339 Regulation of EREG 2 0.27 1.86 0.31
43 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
44 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
45 INT123954 Transcription of Plscr1 1 0.28 0.09 0.27
46 INT123957 Regulation of Plscr1 1 0.11 0.09 0.27
47 INT123953 Regulation of Transcription of Plscr1 1 0.14 0.09 0.27
48 INT324677 Gene_expression of Tirap 3 0.47 0.21 0.26
49 INT207896 Gene_expression of TLR8 3 0.36 2.82 0.26
50 INT346896 Binding of Nod2 1 0.21 0.72 0.26
51 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
52 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
53 INT150203 Positive_regulation of Xcl1 2 0.40 2.47 0.21
54 INT132107 Positive_regulation of Positive_regulation of CD1D 1 0.04 0.16 0.2
55 INT34479 Gene_expression of IFNK 1 0.75 0.88 0.18
56 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
57 INT155154 Binding of CD1D 2 0.36 1.7 0.12
58 INT131015 Negative_regulation of Cd74 1 0.17 0.25 0.12
59 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
60 INT204779 Localization of Nod2 1 0.48 0.6 0.08
61 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
62 INT49285 Regulation of IFNK 1 0.18 0.81 0.06
63 INT334959 Regulation of Gene_expression of TLR8 1 0.21 0.91 0.05
64 INT324127 Positive_regulation of Cd74 2 0.07 1.34 0.04
65 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
66 INT219169 Positive_regulation of Localization of CD1D 1 0.22 0.65 0.03
67 INT307325 Negative_regulation of Gene_expression of EREG 1 0.01 0.31 0.03
68 INT334960 Positive_regulation of Gene_expression of TLR8 1 0.23 0.82 0.03
69 INT345270 Negative_regulation of Tirap 1 0.02 0.15 0
70 INT324126 Negative_regulation of Binding of Cd74 1 0.08 0.31 0
71 INT284053 Positive_regulation of Positive_regulation of Nod2 1 0.25 0.08 0
72 INT254185 Positive_regulation of Tirap 1 0.32 0 0
73 INT254183 Regulation of Positive_regulation of Tirap 1 0.29 0 0
74 INT254176 Positive_regulation of Positive_regulation of Tirap 1 0.32 0 0
75 INT324125 Positive_regulation of Binding of Cd74 1 0.09 0.62 0
76 INT242886 Transcription of TLR8 1 0.21 0.08 0
77 INT336398 Negative_regulation of Gene_expression of CD1D 1 0.15 1 0
78 INT242890 Regulation of Transcription of TLR8 1 0.13 0.09 0
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