GO:0045095

From wiki-pain
Jump to: navigation, search
Name keratin filament
Categary Component
Go Slim No
Go Link GO:0045095
Unique Molecular Interactions 85
Total Molecular Interactions 96
Total Single Events 1061
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for keratin filament. They are ordered first by their pain relevance and then by number of times they were reported for keratin filament. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115514 Binding of PRSS1 and KRT79 1 0.02 1.19 0.26
2 INT320492 KRT7 Positive_regulation of Pip 1 0.00 1.02 0.2
3 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
4 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
5 INT129074 Binding of GRP and TCHP 1 0.00 0.5 0.12
6 INT115511 KRT79 Positive_regulation of PRSS2 1 0.02 0.71 0.12
7 INT115512 KRT79 Negative_regulation of Positive_regulation of PRSS1 1 0.02 0.72 0.12
8 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
9 INT146181 Kdm6a Negative_regulation of Gene_expression of KRT6A 1 0.03 0.31 0.11
10 INT115508 Binding of PRSS2 and KRT79 1 0.02 0.39 0.09
11 INT115509 KRT79 Positive_regulation of Positive_regulation of PRSS2 1 0.02 0.46 0.09
12 INT109959 INS Positive_regulation of FBF1 1 0.27 0.24 0.09
13 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08
14 INT154168 Binding of KRT5 and Ttf1 1 0.02 0.34 0.08
15 INT71392 KRT8 Positive_regulation of Krt13 1 0.01 0.84 0.08
16 INT71391 KRT8 Positive_regulation of Krt20 1 0.01 0.84 0.08
17 INT71390 KRT8 Positive_regulation of Cea 1 0.01 0.84 0.08
18 INT97314 Binding of ETFA and KRT1 1 0.07 0.75 0.08
19 INT154161 Binding of GFAP and KRT5 1 0.40 0.34 0.08
20 INT71388 Krt13 Positive_regulation of Cea 1 0.00 0.84 0.08
21 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07
22 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07
23 INT163492 Binding of TNFRSF8 and KRT7 1 0.26 0.89 0.06
24 INT344225 Binding of fc and Krt1 1 0.00 0.39 0.06
25 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05
26 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05
27 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05
28 INT279763 Binding of IGHG3 and KRT18 1 0.00 0.43 0.04
29 INT219875 Binding of KRT7 and Krt20 1 0.01 1.32 0.04
30 INT279765 Binding of IGHG3 and KRT8 1 0.01 0.42 0.04
31 INT279762 Binding of KRT18 and KRT19 1 0.01 0.43 0.04
32 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03
33 INT132220 Muc5ac Regulation of Gene_expression of KRT7 1 0.01 0.18 0
34 INT132202 Krt20 Regulation of KRT7 1 0.01 0.18 0
35 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0
36 INT132219 Muc2 Regulation of KRT7 1 0.01 0.18 0
37 INT197761 Binding of KRT5 and C4a 1 0.02 2.29 0
38 INT312372 Binding of MME and TCHP 1 0.06 1.56 0
39 INT225957 Binding of KRT3 and KRT12 1 0.18 0.06 0
40 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0
41 INT197762 Binding of KRT5 and Cpe 1 0.19 1.14 0
42 INT344223 Positive_regulation of Binding of fc and Krt1 1 0.00 0 0
43 INT132208 MUC1 Regulation of KRT7 1 0.02 0.18 0
44 INT232895 Krt18 Positive_regulation of Gene_expression of ABR 1 0.46 0.09 0
45 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0
46 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0
47 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0
48 INT132203 Krt20 Regulation of Gene_expression of KRT7 1 0.01 0.18 0
49 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0
50 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0
51 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0
52 INT233771 Binding of KRT7 and KRT20 1 0.01 1.72 0
53 INT232896 Krt8 Negative_regulation of Binding of ABR 1 0.04 0.68 0
54 INT132218 Muc2 Regulation of Gene_expression of KRT7 1 0.01 0.18 0
55 INT232892 Krt18 Positive_regulation of Gene_expression of Krt8 1 0.30 0.09 0
56 INT344221 Binding of C4bp and Krt1 1 0.01 0.5 0
57 INT221124 Binding of KRT1 and IGKV1-22 1 0.02 0 0
58 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0
59 INT232889 Binding of Krt18 and Krt8 1 0.22 1.09 0
60 INT132221 Muc5ac Regulation of KRT7 1 0.01 0.18 0
61 INT132209 MUC1 Regulation of Gene_expression of KRT7 1 0.02 0.18 0
62 INT344227 Binding of C4b and Krt1 1 0.01 0.51 0
63 INT186548 Binding of KRT1 and MAX 1 0.01 0.15 0
64 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for keratin filament. They are ordered first by their pain relevance and then by number of times they were reported in keratin filament. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT24444 Regulation of FBF1 2 0.12 5.55 5.06
2 INT24441 Positive_regulation of FBF1 13 0.39 6.52 4.29
3 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12
4 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07
5 INT24445 Gene_expression of FBF1 2 0.35 2.73 3.63
6 INT24442 Negative_regulation of FBF1 5 0.36 3.38 3.17
7 INT24446 Positive_regulation of Gene_expression of FBF1 2 0.23 3.96 2.72
8 INT354254 Negative_regulation of Regulation of FBF1 1 0.03 2.25 1.67
9 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16
10 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14
11 INT127064 Gene_expression of KRT76 7 0.75 1.71 1.1
12 INT199308 Gene_expression of Krt8 37 0.75 23.17 1.06
13 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05
14 INT83479 Gene_expression of KRT18 30 0.65 27.29 1
15 INT11919 Regulation of KRT1 9 0.10 4.97 0.77
16 INT127633 Localization of KRT18 5 0.52 5.93 0.75
17 INT160736 Negative_regulation of KRT7 9 0.41 10.08 0.68
18 INT145541 Positive_regulation of KRT76 2 0.27 0.08 0.66
19 INT117437 Protein_catabolism of KRT18 3 0.46 4.64 0.61
20 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56
21 INT163221 Protein_catabolism of Krt18 2 0.81 2.18 0.56
22 INT163223 Negative_regulation of Protein_catabolism of Krt18 1 0.35 1.18 0.56
23 INT145540 Regulation of KRT76 2 0.35 0 0.55
24 INT146179 Gene_expression of KRT6A 23 0.75 9.39 0.52
25 INT131931 Binding of KRT7 13 0.36 19.24 0.5
26 INT232826 Gene_expression of Krt18 26 0.68 14.24 0.48
27 INT70445 Binding of KRT1 10 0.35 5.38 0.47
28 INT354255 Negative_regulation of Gene_expression of FBF1 1 0.02 0.74 0.45
29 INT232840 Positive_regulation of Gene_expression of Krt8 1 0.44 4.51 0.42
30 INT232825 Positive_regulation of Krt8 1 0.44 6.83 0.42
31 INT29637 Localization of KRT1 6 0.20 5.55 0.4
32 INT111822 Binding of Krt8 6 0.34 4.61 0.39
33 INT38055 Positive_regulation of KRT3 4 0.64 1.05 0.39
34 INT130889 Regulation of KRT7 4 0.07 3.74 0.39
35 INT127063 Transcription of KRT76 1 0.69 0.17 0.39
36 INT232821 Positive_regulation of Gene_expression of Krt18 11 0.50 4.38 0.31
37 INT345368 Negative_regulation of Krt8 1 0.00 7.25 0.31
38 INT151793 Gene_expression of KRT3 36 0.75 2.32 0.26
39 INT232828 Regulation of Krt18 1 0.50 2.2 0.26
40 INT162564 Gene_expression of KRT2 5 0.59 1.75 0.24
41 INT232845 Positive_regulation of Krt18 1 0.41 4.5 0.24
42 INT232945 Positive_regulation of Gene_expression of KRT18 2 0.49 3.54 0.23
43 INT232982 Localization of KRT8 2 0.44 2.65 0.23
44 INT232967 Positive_regulation of Gene_expression of KRT8 2 0.29 3.54 0.23
45 INT179888 Localization of KRT7 3 0.39 2.85 0.22
46 INT232831 Binding of Krt18 7 0.39 4.61 0.21
47 INT101620 Gene_expression of TCHP 4 0.02 2.18 0.21
48 INT101619 Positive_regulation of Gene_expression of TCHP 2 0.01 1.35 0.21
49 INT214816 Positive_regulation of Positive_regulation of KRT3 1 0.07 0.58 0.21
50 INT232824 Regulation of Krt8 1 0.29 1.64 0.21
51 INT232962 Binding of KRT18 4 0.26 2.38 0.18
52 INT354258 Localization of FBF1 1 0.05 0.23 0.18
53 INT216395 Negative_regulation of Gene_expression of KRT7 4 0.41 3.57 0.16
54 INT146180 Positive_regulation of Gene_expression of KRT6A 2 0.49 1.43 0.16
55 INT274661 Positive_regulation of Binding of KRT7 1 0.45 3.5 0.15
56 INT132194 Positive_regulation of Gene_expression of KRT7 5 0.58 4.18 0.14
57 INT328840 Positive_regulation of Regulation of KRT76 1 0.27 0 0.14
58 INT275477 Negative_regulation of TCHP 1 0.03 0.1 0.13
59 INT328839 Positive_regulation of Negative_regulation of KRT76 1 0.29 0 0.12
60 INT328842 Negative_regulation of KRT76 1 0.34 0 0.12
61 INT115518 Protein_catabolism of KRT79 1 0.05 0.71 0.11
62 INT145490 Binding of KRT76 2 0.36 0.29 0.09
63 INT232839 Phosphorylation of Krt18 1 0.67 1.78 0.09
64 INT70450 Binding of KRT5 6 0.47 5.72 0.08
65 INT232848 Negative_regulation of Gene_expression of Krt18 5 0.36 2.3 0.08
66 INT232822 Negative_regulation of Gene_expression of Krt8 5 0.36 2.3 0.08
67 INT164349 Positive_regulation of KRT8 2 0.10 3.14 0.08
68 INT109961 Positive_regulation of Positive_regulation of FBF1 1 0.14 0.25 0.08
69 INT159192 Negative_regulation of KRT5 1 0.42 0.58 0.08
70 INT344213 Binding of Krt1 1 0.03 2.24 0.08
71 INT221377 Localization of Krt18 4 0.61 1.82 0.07
72 INT103445 Gene_expression of Krt1 2 0.15 2.03 0.07
73 INT232850 Phosphorylation of Krt8 7 0.52 3.8 0.05
74 INT230117 Binding of KRT8 6 0.31 2.44 0.05
75 INT175895 Negative_regulation of KRT1 5 0.37 3.23 0.05
76 INT258830 Negative_regulation of Gene_expression of KRT3 1 0.25 0.15 0.05
77 INT232991 Localization of KRT5 1 0.33 1.36 0.04
78 INT221854 Regulation of Positive_regulation of KRT1 1 0.03 0.86 0.04
79 INT221378 Localization of Krt13 1 0.08 0.2 0.04
80 INT232994 Gene_expression of KRT10 6 0.40 8.2 0.03
81 INT151792 Positive_regulation of Gene_expression of KRT3 3 0.49 0 0.03
82 INT317061 Regulation of Gene_expression of KRT7 2 0.19 0.99 0.03
83 INT187627 Gene_expression of KRT4 5 0.37 4.54 0
84 INT230113 Regulation of KRT8 4 0.46 2.73 0
85 INT225960 Gene_expression of KRT13 4 0.39 2.47 0
86 INT232965 Binding of KRT10 3 0.19 1.66 0
87 INT232942 Negative_regulation of KRT10 3 0.21 1.19 0
88 INT230118 Negative_regulation of KRT8 3 0.36 1.56 0
89 INT232975 Binding of KRT9 2 0.14 0.8 0
90 INT232980 Binding of KRT3 2 0.29 0.43 0
91 INT176161 Binding of TCHP 2 0.06 1.45 0
92 INT258945 Positive_regulation of KRT18 2 0.21 4.52 0
93 INT303344 Localization of Krt1 2 0.20 0 0
94 INT233002 Binding of KRT2 1 0.29 0 0
95 INT317460 Regulation of KRT3 1 0.44 0.2 0
96 INT263797 Negative_regulation of Localization of KRT18 1 0.12 1.42 0
97 INT214457 Transcription of KRT7 1 0.19 1.49 0
98 INT344206 Positive_regulation of Krt1 1 0.03 0.81 0
99 INT232978 Localization of KRT4 1 0.35 0.2 0
100 INT162479 Negative_regulation of Gene_expression of KRT6A 1 0.57 0 0
101 INT344198 Negative_regulation of Localization of Krt1 1 0.02 0 0
102 INT232879 Protein_catabolism of KRT1 1 0.64 0.92 0
103 INT232832 Localization of Krt8 1 0.48 0.84 0
104 INT162475 Regulation of Gene_expression of KRT6A 1 0.60 0 0
105 INT325372 Negative_regulation of Gene_expression of TCHP 1 0.01 0.82 0
106 INT303378 Regulation of Krt1 1 0.12 0 0
107 INT232949 Positive_regulation of KRT10 1 0.25 0.38 0
108 INT232847 Negative_regulation of Protein_catabolism of Krt8 1 0.33 0.13 0
109 INT344210 Positive_regulation of Gene_expression of Krt1 1 0.03 0.43 0
110 INT232990 Localization of KRT6A 1 0.43 0.37 0
111 INT232820 Protein_catabolism of Krt8 1 0.55 0.13 0
112 INT344203 Transcription of Krt1 1 0.04 0 0
113 INT232983 Negative_regulation of KRT13 1 0.26 2.44 0
114 INT232997 Positive_regulation of KRT6A 1 0.40 0.82 0
115 INT232843 Negative_regulation of Krt18 1 0.30 0.2 0
116 INT232985 Positive_regulation of Localization of KRT6A 1 0.29 0.37 0
117 INT233009 Binding of KRT13 1 0.16 1.13 0
118 INT232849 Negative_regulation of Phosphorylation of Krt8 1 0.27 0.24 0
119 INT344195 Positive_regulation of Positive_regulation of Krt1 1 0.03 0.41 0
120 INT232836 Regulation of Gene_expression of Krt8 1 0.29 1.57 0
121 INT344215 Protein_catabolism of Krt1 1 0.04 0 0
122 INT232992 Localization of KRT9 1 0.29 0.47 0
123 INT232961 Localization of KRT13 1 0.38 0.2 0
124 INT322618 Binding of KRT6A 1 0.36 0.56 0
125 INT327160 Negative_regulation of Gene_expression of KRT2 1 0.01 0.15 0
126 INT258831 Negative_regulation of KRT3 1 0.25 0.18 0
127 INT232835 Regulation of Positive_regulation of Krt18 1 0.37 0.71 0
128 INT199005 Localization of KRT2 1 0.05 1.5 0
129 INT214630 Localization of KRT10 1 0.73 0.56 0
130 INT326725 Positive_regulation of Transcription of Krt18 1 0.44 0.19 0
131 INT232846 Regulation of Positive_regulation of Krt8 1 0.29 0.71 0
132 INT344207 Negative_regulation of Binding of Krt1 1 0.02 0 0
133 INT188175 Positive_regulation of Gene_expression of KRT1 1 0.06 0.16 0
134 INT232837 Regulation of Gene_expression of Krt18 1 0.50 1.57 0
135 INT232851 Positive_regulation of Phosphorylation of Krt8 1 0.32 0.47 0
136 INT162477 Negative_regulation of KRT6A 1 0.41 0.17 0
137 INT232960 Negative_regulation of Binding of KRT5 1 0.20 1.68 0
138 INT232946 Positive_regulation of Gene_expression of KRT5 1 0.23 0.33 0
139 INT232969 Positive_regulation of KRT5 1 0.27 1.24 0
140 INT326699 Transcription of Krt18 1 0.63 0.83 0
141 INT232950 Negative_regulation of Gene_expression of KRT8 1 0.25 0.79 0
142 INT226069 Negative_regulation of KRT18 1 0.18 0.72 0
143 INT344216 Positive_regulation of Binding of Krt1 1 0.03 0.41 0
144 INT232968 Negative_regulation of Gene_expression of KRT13 1 0.22 0.11 0
145 INT268697 Positive_regulation of TCHP 1 0.07 1.86 0
146 INT279768 Regulation of KRT18 1 0.03 0.48 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox