GO:0045120

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Name pronucleus
Categary Component
Go Slim No
Go Link GO:0045120
Unique Molecular Interactions 37
Total Molecular Interactions 43
Total Single Events 414
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for pronucleus. They are ordered first by their pain relevance and then by number of times they were reported for pronucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
2 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
3 INT350342 Tbp Positive_regulation of Ltp 1 0.25 0.48 0.64
4 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59
5 INT81915 HSF1 Negative_regulation of IL1B 1 0.51 0.65 0.59
6 INT81917 HSF1 Positive_regulation of IL1B 1 0.41 0.65 0.59
7 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59
8 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21
9 INT132680 HNF1A Positive_regulation of Gene_expression of UGT1A6 1 0.30 0.08 0.21
10 INT132679 HNF1A Regulation of Gene_expression of UGT1A6 1 0.16 0.08 0.21
11 INT62201 Binding of NR5A2 and Hsf1 1 0.00 0.67 0.09
12 INT326573 Zic2 Positive_regulation of Localization of Hsf1 1 0.01 0.95 0.07
13 INT350345 Tbp Positive_regulation of Positive_regulation of Grin1 1 0.18 0 0.07
14 INT239804 HSF1 Positive_regulation of HSR 1 0.16 2.09 0.05
15 INT326571 Binding of Hsf1 and Hsp90ab1 1 0.16 1.19 0.03
16 INT334278 Binding of Tbp and Tk1 1 0.13 0.12 0.03
17 INT334277 Binding of Mki67 and Tbp 1 0.12 0.12 0.03
18 INT284095 HNF1A Positive_regulation of TIMP3 1 0.38 2.3 0
19 INT284092 HNF1A Positive_regulation of FGD2 1 0.15 1.16 0
20 INT333842 Hnf1a Positive_regulation of Mir194-1 1 0.02 0.18 0
21 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0
22 INT284098 HNF1A Positive_regulation of SLC2A1 1 0.36 1.16 0
23 INT215345 Positive_regulation of Binding of Srebf1 and Tbp 1 0.05 0.16 0
24 INT292727 GSK Positive_regulation of Negative_regulation of Hsf1 1 0.21 0 0
25 INT292723 Akt1 Positive_regulation of Localization of Hsf1 1 0.05 0.36 0
26 INT215343 Binding of Srebf1 and Tbp 1 0.04 0.16 0
27 INT292722 Akt1 Regulation of Localization of Hsf1 1 0.06 0 0
28 INT292721 Mapk1 Negative_regulation of Phosphorylation of Hsf1 1 0.02 0.06 0
29 INT311063 ELANE Positive_regulation of HSF1 1 0.18 0.54 0
30 INT311062 ELANE Positive_regulation of Localization of HSF1 1 0.22 0.91 0
31 INT239805 Binding of FUT1 and HSF1 1 0.03 0.37 0
32 INT215342 Binding of Cebpg and Tbp 1 0.00 0.55 0
33 INT311064 HSP90AA1 Positive_regulation of Positive_regulation of HSF1 1 0.20 0.17 0
34 INT311061 HSP90AA1 Positive_regulation of HSF1 1 0.20 0.17 0
35 INT286186 Binding of Blm and Fig4 1 0.09 0.34 0
36 INT311060 ELANE Regulation of Localization of HSF1 1 0.20 0.74 0
37 INT239803 Positive_regulation of HSF1 Positive_regulation of HSR 1 0.15 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for pronucleus. They are ordered first by their pain relevance and then by number of times they were reported in pronucleus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66919 Positive_regulation of HSF1 27 0.69 14.78 3.24
2 INT81928 Positive_regulation of Binding of HSF1 4 0.49 3.04 1.67
3 INT81926 Binding of HSF1 10 0.47 5.05 1.53
4 INT55315 Gene_expression of Tbp 32 0.74 14.6 1.17
5 INT81921 Gene_expression of HSF1 17 0.76 9.19 1.08
6 INT62195 Positive_regulation of Hsf1 17 0.70 11.51 0.95
7 INT52454 Localization of Tbp 7 0.76 2.53 0.91
8 INT52455 Negative_regulation of Tbp 3 0.25 1.75 0.91
9 INT81930 Positive_regulation of Gene_expression of HSF1 4 0.66 4.07 0.88
10 INT129678 Gene_expression of Hsf1 13 0.78 8.57 0.85
11 INT71876 Regulation of Tbp 4 0.43 1.03 0.8
12 INT81923 Negative_regulation of Gene_expression of HSF1 2 0.42 1.17 0.73
13 INT66918 Regulation of HSF1 8 0.43 4.18 0.61
14 INT62199 Binding of Hsf1 12 0.45 10.77 0.6
15 INT163993 Gene_expression of Hnf1a 2 0.65 1.38 0.49
16 INT62200 Phosphorylation of Hsf1 9 0.76 4.74 0.46
17 INT66917 Negative_regulation of HSF1 2 0.43 1.33 0.4
18 INT350319 Negative_regulation of Localization of Tbp 1 0.20 0 0.4
19 INT267202 Localization of Hsf1 14 0.68 7.8 0.28
20 INT215331 Positive_regulation of Tbp 8 0.66 1.73 0.26
21 INT62196 Positive_regulation of Positive_regulation of Hsf1 3 0.47 2.72 0.25
22 INT199276 Binding of Tbp 12 0.46 2.67 0.24
23 INT129679 Negative_regulation of Hsf1 9 0.43 3.22 0.22
24 INT20301 Positive_regulation of Binding of Hnf1a 1 0.02 0 0.21
25 INT354941 Negative_regulation of Gene_expression of Tbp 1 0.17 0 0.21
26 INT20302 Binding of Hnf1a 1 0.02 0 0.2
27 INT129682 Positive_regulation of Gene_expression of Hsf1 2 0.50 1.92 0.17
28 INT129680 Transcription of Hsf1 2 0.53 1.68 0.17
29 INT129683 Negative_regulation of Transcription of Hsf1 1 0.43 1.03 0.17
30 INT62198 Positive_regulation of Phosphorylation of Hsf1 3 0.47 1.59 0.15
31 INT249107 Positive_regulation of HNF1A 1 0.49 0.2 0.13
32 INT62197 Positive_regulation of Binding of Hsf1 1 0.47 0.64 0.1
33 INT286183 Regulation of Blm 1 0.36 1.3 0.09
34 INT286184 Gene_expression of Blm 1 0.39 2.16 0.09
35 INT239822 Protein_catabolism of HSF1 1 0.62 0.63 0.05
36 INT239826 Phosphorylation of HSF1 1 0.78 0.53 0.05
37 INT239829 Regulation of Regulation of HSF1 1 0.43 0.38 0.05
38 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05
39 INT239825 Localization of HSF1 8 0.71 6.45 0
40 INT239817 Positive_regulation of Positive_regulation of HSF1 6 0.48 2.88 0
41 INT292703 Regulation of Hsf1 5 0.26 1.78 0
42 INT239816 Positive_regulation of Localization of HSF1 5 0.48 3.72 0
43 INT205576 Positive_regulation of Hnf1a 2 0.49 1.1 0
44 INT292707 Negative_regulation of Gene_expression of Hsf1 1 0.16 0.55 0
45 INT215318 Regulation of Localization of Tbp 1 0.43 0.58 0
46 INT215337 Positive_regulation of Gene_expression of Tbp 1 0.48 0.45 0
47 INT240923 Regulation of Hnf1a 1 0.19 0.48 0
48 INT296535 Regulation of Gene_expression of Hsf1 1 0.60 1.76 0
49 INT239830 Regulation of Positive_regulation of HSF1 1 0.43 0.16 0
50 INT339087 Binding of Ezh2 1 0.37 1.14 0
51 INT292702 Regulation of Regulation of Hsf1 1 0.10 0 0
52 INT292701 Negative_regulation of Localization of Hsf1 1 0.22 0 0
53 INT311068 Negative_regulation of Binding of HSF1 1 0.37 0.72 0
54 INT292708 Regulation of Localization of Hsf1 1 0.17 0 0
55 INT292704 Positive_regulation of Localization of Hsf1 1 0.26 0.15 0
56 INT215339 Positive_regulation of Positive_regulation of Tbp 1 0.48 0.42 0
57 INT286182 Positive_regulation of Gene_expression of Blm 1 0.29 0.53 0
58 INT292705 Regulation of Binding of Hsf1 1 0.10 0.89 0
59 INT339090 Positive_regulation of Ezh2 1 0.47 0.82 0
60 INT239818 Regulation of Gene_expression of HSF1 1 0.43 0.1 0
61 INT239820 Positive_regulation of Phosphorylation of HSF1 1 0.48 0.14 0
62 INT292706 Regulation of Positive_regulation of Hsf1 1 0.10 0.17 0
63 INT215323 Positive_regulation of Binding of Tbp 1 0.48 0.91 0
64 INT339091 Positive_regulation of Gene_expression of Ezh2 1 0.70 11.65 0
65 INT205577 Positive_regulation of Gene_expression of Hnf1a 1 0.49 1.1 0
66 INT339095 Negative_regulation of Gene_expression of Ezh2 1 0.59 4.48 0
67 INT339089 Regulation of Gene_expression of Ezh2 1 0.45 3.76 0
68 INT215336 Positive_regulation of Localization of Tbp 1 0.48 0.57 0
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