GO:0045121

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Name membrane raft
Categary Component
Go Slim No
Go Link GO:0045121
Unique Molecular Interactions 5297
Total Molecular Interactions 7320
Total Single Events 68297
Pain Genes Associated 249

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for membrane raft. They are ordered first by their pain relevance and then by number of times they were reported for membrane raft. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT21276 Binding of Oprd1 and Penk 9 0.54 1.14 8.28
3 INT259228 Binding of Oprm1 and Glul 1 0.00 0.08 7.22
4 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
5 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
6 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
7 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
8 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
9 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
10 INT40114 Binding of OPRD1 and Oprm1 2 0.00 0 4.29
11 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
12 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
13 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
14 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
15 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
16 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85
17 INT249566 Binding of Oprd1 and Psmd1 1 0.01 0.82 3.8
18 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
19 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
20 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
21 INT137918 Oprm1 Positive_regulation of Pdgfrb 1 0.41 0 3.31
22 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
23 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
24 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
25 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
26 INT158751 Binding of TRPV1 and Pag1 1 0.03 1.59 3.08
27 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03
28 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
29 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
30 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
31 INT137230 Trh Regulation of Gene_expression of Oprd1 1 0.01 1.62 2.75
32 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
33 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
34 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68
35 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
36 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
37 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
38 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
39 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
40 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
41 INT150596 Binding of Oprd1 and Oprk1 1 0.08 0.14 2.59
42 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
43 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
44 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
45 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
46 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
47 INT69665 Binding of Oprd1 and Pnoc 5 0.35 0.4 2.5
48 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 0.01 0.66 2.5
49 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49
50 INT14687 Binding of Penk and Ppt1 1 0.41 0 2.46
51 INT96462 Pnoc Positive_regulation of Pag1 1 0.01 0.74 2.45
52 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
53 INT231970 Binding of Cpn1 and Pag1 1 0.07 1.56 2.44
54 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
55 INT37873 Pag1 Regulation of Nrm 2 0.04 1.1 2.41
56 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
57 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
58 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
59 INT158809 Pag1 Regulation of Rvm 1 0.02 1.28 2.33
60 INT154226 Positive_regulation of Oprk1 Negative_regulation of Negative_regulation of Oprm1 1 0.28 0.07 2.32
61 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
62 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27
63 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
64 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
65 INT211748 Binding of Pag1 and Mors1 2 0.07 0.2 2.26
66 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
67 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
68 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
69 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
70 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
71 INT5486 Oprd1 Regulation of Cck 1 0.21 0 2.16
72 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
73 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14
74 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
75 INT344386 Efnb1 Positive_regulation of Phosphorylation of Ephb2 1 0.15 2.85 2.13
76 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
77 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
78 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
79 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
80 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
81 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
82 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
83 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
84 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
85 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
86 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98
87 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
88 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
89 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
90 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
91 INT146099 Binding of Oprm1 and Rgs9 1 0.48 0 1.95
92 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94
93 INT68272 Binding of Oprd1 and G2e3 1 0.00 0.11 1.93
94 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
95 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
96 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
97 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
98 INT169498 Binding of Oprm1 and Mirlet7a-1 1 0.32 0 1.9
99 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
100 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
101 INT153582 Binding of Oprm1 and Hint1 1 0.01 0 1.87
102 INT211747 Negative_regulation of Binding of Oprm1 and Mors1 1 0.09 0 1.86
103 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
104 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
105 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84
106 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83
107 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
108 INT119917 Zfp821 Positive_regulation of Positive_regulation of Oprd1 1 0.01 0 1.82
109 INT169502 Mirlet7a-1 Regulation of Oprm1 1 0.53 0 1.81
110 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
111 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
112 INT70225 oh Regulation of Oprd1 1 0.20 0.13 1.8
113 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
114 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
115 INT168925 Binding of Oprm1 and Imraq2 1 0.04 0.13 1.78
116 INT168924 Positive_regulation of Binding of Oprm1 and Imraq2 1 0.06 0.13 1.78
117 INT211746 Binding of Oprm1 and Mors1 1 0.08 0 1.78
118 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
119 INT149491 PNOC Negative_regulation of Gene_expression of CD14 1 0.40 0.37 1.76
120 INT129953 Oprd1 Regulation of Cspg5 1 0.17 0.15 1.74
121 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
122 INT37840 Binding of Cyp27b1 and Oprd1 1 0.01 0 1.73
123 INT6407 Binding of Lama5 and Oprm1 1 0.02 0.08 1.72
124 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
125 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
126 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
127 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
128 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
129 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
130 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
131 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
132 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
133 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
134 INT149680 Binding of Parp1 and Oprm1 1 0.53 0 1.66
135 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
136 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
137 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64
138 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
139 INT61049 Binding of Oprd1 and Negative_regulation of Gene_expression of Odc1 1 0.21 0 1.64
140 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
141 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64
142 INT90046 Oprm1 Positive_regulation of P9Ehs1 2 0.16 0.92 1.63
143 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63
144 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
145 INT61674 Gpm6a Regulation of Oprd1 1 0.01 0.07 1.62
146 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
147 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
148 INT180812 Gdnf Positive_regulation of Gene_expression of Sorbs1 1 0.02 0.83 1.61
149 INT180811 Gdnf Positive_regulation of Regulation of Sorbs1 1 0.01 0.83 1.61
150 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
151 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
152 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
153 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
154 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59
155 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
156 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
157 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
158 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
159 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
160 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
161 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
162 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
163 INT148820 Binding of Oprm1 and Naa15 1 0.02 0.24 1.55
164 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
165 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
166 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
167 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
168 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
169 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53
170 INT111828 UPB1 Positive_regulation of Oprm1 1 0.00 0.85 1.53
171 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
172 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
173 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
174 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
175 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
176 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
177 INT8735 Oprm1 Positive_regulation of Scn4a 1 0.00 0 1.49
178 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
179 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
180 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
181 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
182 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
183 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46
184 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
185 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
186 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
187 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
188 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
189 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
190 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
191 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
192 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
193 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
194 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
195 INT19013 Ghsr Negative_regulation of Localization of Sst 1 0.15 0 1.44
196 INT180804 Bdnf Positive_regulation of Gene_expression of Sorbs1 1 0.01 0 1.44
197 INT19012 Ghsr Negative_regulation of Localization of Sstr1 1 0.10 0 1.44
198 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
199 INT125856 Positive_regulation of Oprm1 Regulation of Positive_regulation of Insrr 1 0.01 0.26 1.43
200 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for membrane raft. They are ordered first by their pain relevance and then by number of times they were reported in membrane raft. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29
3 INT5660 Binding of Oprd1 477 0.48 71.86 342.06
4 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
5 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
6 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32
7 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71
8 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41
9 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
10 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
11 INT6852 Localization of TNF 883 0.81 705.95 270.84
12 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9
13 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87
14 INT6406 Binding of Oprm1 280 0.48 40.54 226.26
15 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
16 INT6481 Binding of TNF 624 0.48 510.2 214.82
17 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
18 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
19 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
20 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85
21 INT26472 Regulation of Oprm1 191 0.62 35.84 173.1
22 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
23 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11
24 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
25 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
26 INT9660 Regulation of TNF 363 0.62 312.94 139.99
27 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
28 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
29 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
30 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
31 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
32 INT12569 Localization of Oprd1 94 0.81 23.81 104.56
33 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
34 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76
35 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79
36 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
37 INT10166 Localization of Tnf 237 0.81 153.95 88.64
38 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88
39 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
40 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
41 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
42 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
43 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
44 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
45 INT6926 Regulation of Pag1 72 0.39 55.79 65.09
46 INT8733 Localization of Oprm1 61 0.75 7.55 64.61
47 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23
48 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
49 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83
50 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65
51 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
52 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
53 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
54 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11
55 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54
56 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
57 INT7800 Localization of Pag1 51 0.56 33.06 53.74
58 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
59 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
60 INT10668 Positive_regulation of Gene_expression of Oprd1 61 0.69 15.21 52.12
61 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02
62 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24
63 INT32718 Gene_expression of OPRD1 82 0.76 9.43 48.38
64 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
65 INT62521 Phosphorylation of Oprm1 44 0.82 2.66 47.45
66 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
67 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
68 INT7828 Positive_regulation of Oprd1 55 0.69 14.11 42.86
69 INT13354 Transcription of TNF 108 0.72 85.81 42.32
70 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11
71 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
72 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
73 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22
74 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5
75 INT6067 Positive_regulation of Positive_regulation of Oprd1 37 0.69 6.56 36.58
76 INT64436 Gene_expression of P2rx1 93 0.78 32.69 36.12
77 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
78 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
79 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
80 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
81 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29
82 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
83 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
84 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
85 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43
86 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
87 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13
88 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05
89 INT21560 Positive_regulation of Binding of Oprm1 30 0.50 7.16 32.95
90 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86
91 INT35406 Localization of Tnf 94 0.81 64.63 31.65
92 INT12397 Gene_expression of Oprd1 53 0.78 9.1 31.31
93 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
94 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
95 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75
96 INT16769 Positive_regulation of Positive_regulation of Oprm1 31 0.57 8.29 29.66
97 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22
98 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
99 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68
100 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
101 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
102 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
103 INT5771 Binding of Oprd1 37 0.48 2.6 27.54
104 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4
105 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
106 INT72677 Regulation of Gene_expression of Oprm1 45 0.62 13.95 26.75
107 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
108 INT6382 Regulation of Binding of Oprd1 36 0.61 7 26.48
109 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2
110 INT6934 Binding of OPRD1 51 0.48 7.72 25.73
111 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
112 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
113 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
114 INT79979 Gene_expression of Ret 94 0.75 19.21 25.51
115 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
116 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
117 INT256285 Gene_expression of Efnb1 32 0.70 36.25 24.73
118 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
119 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52
120 INT254567 Positive_regulation of Gene_expression of PAG1 10 0.39 31.15 24.26
121 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03
122 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23
123 INT134651 Binding of TLR4 89 0.48 66.96 23.19
124 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09
125 INT30386 Negative_regulation of OPRD1 33 0.52 4.34 23.06
126 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92
127 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
128 INT57253 Negative_regulation of Binding of Oprm1 24 0.43 5.27 22.67
129 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54
130 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
131 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
132 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
133 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
134 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83
135 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
136 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
137 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
138 INT31393 Positive_regulation of Localization of Oprd1 10 0.66 7.32 21.23
139 INT4894 Transcription of Ppt1 34 0.67 5.93 21.06
140 INT117527 Binding of Prkca 25 0.48 6.43 21.05
141 INT19580 Binding of Pag1 24 0.30 15.13 20.88
142 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
143 INT27529 Phosphorylation of Oprd1 23 0.47 1.16 20.18
144 INT49835 Negative_regulation of Positive_regulation of Oprm1 21 0.42 4.11 20.11
145 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
146 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
147 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
148 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41
149 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
150 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
151 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
152 INT91916 Gene_expression of P2rx3 51 0.78 21.2 19.05
153 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
154 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19
155 INT109379 Regulation of Phosphorylation of Ephb1 22 0.59 12.58 18.84
156 INT99058 Regulation of PAG1 18 0.45 21.62 18.5
157 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
158 INT31905 Positive_regulation of Binding of Oprd1 21 0.66 3.31 18.44
159 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
160 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78
161 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
162 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
163 INT8332 Positive_regulation of OPRD1 30 0.61 3.88 17.65
164 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53
165 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
166 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
167 INT78233 Positive_regulation of P2rx3 36 0.56 21.49 17.25
168 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16
169 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79
170 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
171 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
172 INT6066 Negative_regulation of Positive_regulation of Oprd1 15 0.43 1.36 16.63
173 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61
174 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
175 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
176 INT33915 Regulation of Positive_regulation of Oprm1 22 0.60 2.44 16.43
177 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
178 INT4769 Regulation of OPRD1 20 0.44 2.05 15.97
179 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
180 INT79458 Localization of Prkca 30 0.81 11.13 15.78
181 INT68913 Gene_expression of Cd14 55 0.76 38.99 15.67
182 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
183 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
184 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
185 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4
186 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36
187 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
188 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21
189 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
190 INT68811 Regulation of Transcription of Oprm1 19 0.61 3.67 15.15
191 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
192 INT12658 Regulation of Binding of Oprm1 9 0.57 2.44 14.95
193 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93
194 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
195 INT63553 Binding of PAG1 14 0.48 12.51 14.76
196 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
197 INT29352 Negative_regulation of Oprd1 16 0.58 6.51 14.6
198 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52
199 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
200 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
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