GO:0045165

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Name cell fate commitment
Categary Process
Go Slim No
Go Link GO:0045165
Unique Molecular Interactions 550
Total Molecular Interactions 764
Total Single Events 7368
Pain Genes Associated 59

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell fate commitment. They are ordered first by their pain relevance and then by number of times they were reported for cell fate commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
2 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
3 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
4 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
5 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
6 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
7 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
8 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
9 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
10 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
11 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
12 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
13 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
14 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
15 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
16 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
17 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
18 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
19 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
20 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
21 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
22 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
23 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
24 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
25 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
26 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
27 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
28 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
29 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
30 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
31 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
32 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
33 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
34 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
35 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
36 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
37 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
38 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
39 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
40 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
41 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
42 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
43 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
44 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84
45 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
46 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
47 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
48 INT224281 Bdnf Regulation of Gene_expression of Gap43 1 0.36 0.4 0.77
49 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
50 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
51 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
52 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
53 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
54 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
55 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
56 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
57 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
58 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
59 INT11558 POMC Positive_regulation of CASP3 1 0.05 0 0.62
60 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
61 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
62 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
63 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
64 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
65 INT147274 Bdnf Regulation of Gap43 1 0.37 0 0.55
66 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
67 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
68 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
69 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
70 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
71 INT234609 Binding of CASP3 and IMMT 1 0.00 0.5 0.5
72 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
73 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
74 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
75 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
76 INT288265 Binding of FLG and NEUROG1 1 0.02 1.06 0.46
77 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
78 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
79 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
80 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
81 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
82 INT70010 Binding of Neurod1 and Insrr 1 0.01 0.11 0.37
83 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
84 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
85 INT337156 Kdr Positive_regulation of Gtf3a 1 0.01 0.77 0.35
86 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34
87 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
88 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
89 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
90 INT353208 NEUROG2 Positive_regulation of Gene_expression of HTR1A 1 0.05 0.35 0.31
91 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
92 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
93 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
94 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
95 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3
96 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
97 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
98 INT250856 Fgf8 Positive_regulation of Localization of Mmp3 1 0.11 0.51 0.3
99 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
100 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28
101 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
102 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28
103 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28
104 INT337162 Binding of Kdr and Iqgap1 1 0.32 0.98 0.28
105 INT298277 Pou4f1 Negative_regulation of Gene_expression of Neurod1 1 0.58 0.48 0.27
106 INT298280 Pou4f1 Negative_regulation of Gene_expression of Neurod4 1 0.38 0.48 0.27
107 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
108 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26
109 INT68298 Binding of Neurod1 and Abt1 1 0.24 0 0.26
110 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
111 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
112 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
113 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
114 INT213804 Binding of Mitf and Tfeb 1 0.24 0.81 0.24
115 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
116 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
117 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23
118 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23
119 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
120 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
121 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
122 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
123 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
124 INT310497 Neurog2 Positive_regulation of Fate1 1 0.07 0.36 0.21
125 INT52459 Binding of SUCLA2 and HEY2 1 0.01 0.09 0.21
126 INT305203 Epo Positive_regulation of Gene_expression of Neurog1 1 0.06 0.4 0.21
127 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
128 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
129 INT203527 Pou4f1 Negative_regulation of Neurod1 1 0.32 0.54 0.2
130 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
131 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
132 INT203531 Pou4f1 Negative_regulation of Neurod4 1 0.46 0.54 0.2
133 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19
134 INT244054 Prkaca Regulation of Neurod1 1 0.02 0.06 0.19
135 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
136 INT310498 Gene_expression of Neurog2 Positive_regulation of Positive_regulation of Eomes 1 0.20 0.42 0.19
137 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
138 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
139 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
140 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
141 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
142 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
143 INT81297 Positive_regulation of Pparg Regulation of Gene_expression of Nos2 1 0.23 0.17 0.17
144 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
145 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
146 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
147 INT213817 Phosphorylation of Tfe3 Positive_regulation of Mitf 1 0.22 1.22 0.15
148 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
149 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
150 INT251528 Binding of CRYGD and NEUROG1 1 0.00 0.38 0.15
151 INT213800 Kit Positive_regulation of Mitf 1 0.30 1.24 0.15
152 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
153 INT213807 Mitf Positive_regulation of Spg21 1 0.05 1.2 0.15
154 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
155 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
156 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15
157 INT106506 Binding of Pparg and Ptgds 1 0.42 0.31 0.14
158 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
159 INT250863 Fgf8 Positive_regulation of Ptger2 1 0.03 0.19 0.14
160 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14
161 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
162 INT275408 Binding of ITIH4 and Gap43 1 0.03 0.64 0.13
163 INT109410 RASGRP1 Regulation of Gene_expression of PPARG 1 0.03 0.76 0.13
164 INT275392 Binding of Gap43 and Htatsf1 1 0.01 0.64 0.13
165 INT115145 PPARG Positive_regulation of TFAM 1 0.04 0.45 0.13
166 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
167 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13
168 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
169 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
170 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13
171 INT230761 VEGFA Positive_regulation of Kdr 2 0.02 2.16 0.12
172 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
173 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
174 INT101173 Pparg Regulation of Positive_regulation of Nfkb1 1 0.03 0.07 0.12
175 INT337155 Binding of Kdr and Ros1 1 0.06 0.46 0.12
176 INT201754 CASP8 Positive_regulation of Casp3 1 0.00 0.47 0.12
177 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
178 INT101174 Pparg Regulation of Gene_expression of IK 1 0.00 0.07 0.12
179 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
180 INT337159 Binding of ecs and Kdr 1 0.04 0.46 0.12
181 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
182 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
183 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
184 INT250866 Binding of Fgfr4 and Fgf8 1 0.12 0.35 0.11
185 INT234062 Nes Positive_regulation of Casp3 1 0.18 0.08 0.11
186 INT139558 Chrna4 Regulation of Neurod1 1 0.17 0 0.1
187 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
188 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1
189 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
190 INT139557 Chrna4 Regulation of Gene_expression of Neurod1 1 0.17 0 0.1
191 INT250860 Fgf8 Regulation of Localization of Ptger2 1 0.02 0.13 0.1
192 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
193 INT250862 Fgf8 Regulation of Localization of Mmp3 1 0.13 0.13 0.1
194 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
195 INT157265 PPARG Positive_regulation of PPARA 1 0.22 1.15 0.09
196 INT299955 Binding of KDR and FTSJ3 1 0.04 1.07 0.09
197 INT250859 Fgf8 Negative_regulation of Gene_expression of Mmp3 1 0.09 0.12 0.09
198 INT250872 Fgf8 Positive_regulation of Mmp3 1 0.11 0.12 0.09
199 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
200 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell fate commitment. They are ordered first by their pain relevance and then by number of times they were reported in cell fate commitment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
5 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
6 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
7 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
8 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
9 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
10 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
11 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
12 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
13 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
14 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45
15 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
16 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
17 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
18 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
19 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
20 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
21 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
22 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
23 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
24 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
25 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
26 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
27 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
28 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
29 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
30 INT67612 Binding of PPARG 38 0.48 22.67 8.94
31 INT10241 Positive_regulation of Gap43 26 0.70 9.89 8.54
32 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
33 INT98178 Localization of Casp3 32 0.65 21.01 7.77
34 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
35 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
36 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
37 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
38 INT20423 Positive_regulation of Gene_expression of Gap43 16 0.70 6.63 6.8
39 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
40 INT57232 Binding of Casp3 22 0.36 9.42 6.2
41 INT250832 Gene_expression of Fgf8 1 0.77 13.36 6.2
42 INT67609 Binding of Pparg 17 0.46 9.53 6.06
43 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
44 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
45 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
46 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
47 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
48 INT58919 Localization of Gap43 10 0.78 3.53 4.61
49 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
50 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
51 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
52 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
53 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
54 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
55 INT20422 Regulation of Gap43 10 0.61 5.24 3.73
56 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7
57 INT97126 Regulation of CASP3 9 0.40 8.15 3.6
58 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
59 INT78845 Binding of Pparg 16 0.44 11.67 3.53
60 INT132385 Gene_expression of Neurog2 12 0.73 7.03 3.44
61 INT137532 Negative_regulation of HEY2 1 0.31 1.69 3.18
62 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
63 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
64 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
65 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
66 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
67 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
68 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
69 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
70 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
71 INT84390 Negative_regulation of Gap43 6 0.58 1.82 2.61
72 INT127113 Positive_regulation of Phosphorylation of Smad2 1 0.68 2.38 2.51
73 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
74 INT31118 Localization of Casp3 17 0.73 11.55 2.3
75 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29
76 INT194504 Gene_expression of Smad2 27 0.65 7.45 2.25
77 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
78 INT78844 Regulation of Pparg 6 0.41 4 2.19
79 INT104512 Regulation of Gene_expression of Gap43 4 0.58 1.27 2.18
80 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14
81 INT41775 Gene_expression of NEUROG1 10 0.71 5.46 2.14
82 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
83 INT82048 Positive_regulation of Neurod1 7 0.49 2.39 2.13
84 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
85 INT48757 Transcription of Gap43 2 0.66 1.5 2.03
86 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
87 INT147896 Negative_regulation of Gene_expression of Gap43 6 0.58 1.01 1.94
88 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86
89 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
90 INT201993 Binding of NEUROG1 4 0.09 4.62 1.85
91 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
92 INT162725 Binding of Kdr 13 0.42 8.86 1.79
93 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
94 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
95 INT250841 Positive_regulation of Gene_expression of Fgf8 1 0.69 3.8 1.72
96 INT97062 Binding of PML 10 0.41 11.63 1.65
97 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
98 INT117438 Positive_regulation of Gene_expression of Pparg 11 0.69 8 1.63
99 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62
100 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
101 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55
102 INT65602 Negative_regulation of Neurod1 7 0.42 2.52 1.55
103 INT127115 Regulation of Phosphorylation of Smad2 1 0.60 1.74 1.53
104 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
105 INT58195 Positive_regulation of Neurog1 2 0.39 1.21 1.51
106 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
107 INT94395 Binding of Gap43 4 0.33 2.41 1.47
108 INT64371 Positive_regulation of Gene_expression of Neurod1 4 0.64 1.56 1.45
109 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44
110 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
111 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
112 INT237409 Localization of Erbb4 3 0.57 1.31 1.41
113 INT48760 Regulation of Transcription of Gap43 1 0.43 1.26 1.4
114 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
115 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
116 INT129619 Phosphorylation of Smad2 34 0.61 11.6 1.34
117 INT199567 Binding of Kdr 18 0.47 13.81 1.34
118 INT250850 Negative_regulation of Gene_expression of Fgf8 1 0.42 2.79 1.33
119 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
120 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
121 INT294804 Positive_regulation of Gene_expression of Neurog2 3 0.57 2.69 1.26
122 INT153757 Positive_regulation of Mitf 10 0.46 8.38 1.22
123 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
124 INT105270 Positive_regulation of KDR 25 0.49 11.49 1.2
125 INT110780 Localization of Notch1 2 0.06 0.47 1.19
126 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
127 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
128 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
129 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
130 INT250840 Negative_regulation of Fgf8 1 0.43 1.92 1.11
131 INT203483 Binding of Neurod4 1 0.36 1.96 1.09
132 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
133 INT79689 Regulation of PPARG 10 0.62 8.04 1.07
134 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
135 INT102845 Localization of CASP3 7 0.81 2.81 1.06
136 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
137 INT277461 Positive_regulation of Gene_expression of Fgf8 1 0.24 0.47 1.05
138 INT94210 Regulation of Neurod1 2 0.33 0.07 1.04
139 INT98817 Regulation of Pparg 3 0.26 1.62 1.03
140 INT200556 Regulation of Kdr 8 0.28 6.04 1.01
141 INT260471 Positive_regulation of Gene_expression of Kdr 9 0.61 8.37 0.99
142 INT6833 Binding of Notch1 4 0.36 0.05 0.94
143 INT31117 Binding of Casp3 14 0.23 5.27 0.93
144 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
145 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92
146 INT114664 Binding of BMP2 12 0.37 6.54 0.91
147 INT107714 Localization of PPARG 4 0.73 0.88 0.91
148 INT168888 Transcription of Neurod4 2 0.66 0.62 0.89
149 INT203502 Gene_expression of Neurog1 4 0.64 1.58 0.87
150 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
151 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
152 INT41774 Positive_regulation of NEUROG1 2 0.40 1.81 0.85
153 INT103400 Transcription of Pparg 2 0.67 3.15 0.85
154 INT183517 Negative_regulation of Neurog1 2 0.35 1.28 0.85
155 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
156 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
157 INT173100 Binding of KDR 39 0.39 22.48 0.81
158 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
159 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
160 INT267095 Regulation of Gene_expression of Smad2 3 0.44 1.77 0.8
161 INT297469 Regulation of Binding of Kdr 1 0.54 2.01 0.8
162 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77
163 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
164 INT137007 Gene_expression of SMAD2 6 0.75 2.53 0.75
165 INT265318 Negative_regulation of Gene_expression of Smad2 8 0.26 2.16 0.72
166 INT262726 Localization of PML 6 0.57 7.13 0.72
167 INT217098 Gene_expression of Hoxa2 1 0.77 2.23 0.72
168 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
169 INT127684 Negative_regulation of Kdr 6 0.37 3.19 0.7
170 INT110089 Positive_regulation of Binding of PPARG 1 0.70 1.04 0.7
171 INT269896 Positive_regulation of Gene_expression of Smad2 9 0.40 2.15 0.69
172 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
173 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
174 INT16800 Phosphorylation of Gap43 3 0.62 1.01 0.67
175 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
176 INT178489 Negative_regulation of Kdr 31 0.42 25.65 0.66
177 INT137009 Negative_regulation of Gene_expression of SMAD2 4 0.42 1.76 0.66
178 INT94148 Positive_regulation of Binding of Pparg 2 0.43 1.16 0.66
179 INT268377 Phosphorylation of SMAD2 7 0.80 0.85 0.65
180 INT131976 Positive_regulation of Protein_catabolism of CASP3 4 0.49 3.76 0.64
181 INT302664 Positive_regulation of SMAD2 2 0.49 0.85 0.64
182 INT237411 Negative_regulation of Localization of Erbb4 1 0.25 0.08 0.64
183 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
184 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
185 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
186 INT116288 Negative_regulation of Pparg 4 0.42 1.69 0.62
187 INT148385 Positive_regulation of HEY2 1 0.38 1.09 0.62
188 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
189 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
190 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
191 INT242061 Positive_regulation of Negative_regulation of Casp3 3 0.09 1.7 0.58
192 INT165706 Negative_regulation of Negative_regulation of PPARG 3 0.23 1.05 0.58
193 INT213774 Positive_regulation of Positive_regulation of Mitf 1 0.31 1.53 0.58
194 INT224279 Positive_regulation of Positive_regulation of Gap43 3 0.39 2.08 0.57
195 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
196 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
197 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
198 INT115156 Regulation of Positive_regulation of PPARG 2 0.25 0.86 0.54
199 INT130600 Negative_regulation of Binding of Pparg 1 0.42 1.96 0.54
200 INT144098 Localization of Pparg 2 0.59 0.73 0.52
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