GO:0045177

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Name apical part of cell
Categary Component
Go Slim No
Go Link GO:0045177
Unique Molecular Interactions 1395
Total Molecular Interactions 1998
Total Single Events 18755
Pain Genes Associated 99

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for apical part of cell. They are ordered first by their pain relevance and then by number of times they were reported for apical part of cell. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227157 Binding of PEBP1 and Gpm6a 1 0.00 1.28 5.52
2 INT143946 Binding of Pebp1 and Mastl 1 0.00 2.04 3.82
3 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
4 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
5 INT255317 Binding of Dpep1 and Nav1 1 0.01 0 2.42
6 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34
7 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
8 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
9 INT255318 Binding of Dpep1 and Nrcam 1 0.00 0 2.16
10 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
11 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
12 INT297488 Itpr3 Regulation of Positive_regulation of Ltp 1 0.02 0.47 1.87
13 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
14 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
15 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
16 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
17 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
18 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
19 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
20 INT45816 Binding of Car2 and Gabrg1 2 0.28 0.15 1.63
21 INT141907 F2r Regulation of Plat 1 0.46 0 1.59
22 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
23 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
24 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55
25 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
26 INT8734 Pebp1 Positive_regulation of Oprd1 1 0.01 0 1.54
27 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
28 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
29 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
30 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
31 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
32 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
33 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
34 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
35 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
36 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
37 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
38 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
39 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
40 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
41 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
42 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
43 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
44 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
45 INT62381 ADCY10 Positive_regulation of Localization of IGHG3 1 0.04 0.36 1.11
46 INT62380 ADCY10 Positive_regulation of IGHG3 1 0.03 0.36 1.11
47 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
48 INT31549 Binding of Dbh and Vip 1 0.32 0 1.08
49 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
50 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
51 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
52 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05
53 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
54 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
55 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
56 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
57 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
58 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
59 INT31548 Binding of Th and Dbh 1 0.35 0 0.98
60 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
61 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
62 INT274899 Positive_regulation of P2rx4 Positive_regulation of Localization of Gtf3a 1 0.02 1.67 0.95
63 INT42482 Binding of Cpe and Pebp1 1 0.02 0 0.95
64 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
65 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
66 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
67 INT75200 Umod Positive_regulation of Transcription of Psma4 1 0.02 1.04 0.92
68 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
69 INT72917 Binding of Crh and Crhr1 4 0.32 0.73 0.91
70 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
71 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
72 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
73 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
74 INT102932 Nos3 Positive_regulation of NOS1 1 0.03 1.63 0.82
75 INT110118 A630055G03Rik Regulation of Car2 1 0.01 0.35 0.81
76 INT270217 Binding of C2 and Ca2 1 0.03 1.63 0.81
77 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
78 INT140922 Btnl2 Negative_regulation of EDA 1 0.00 0.88 0.8
79 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 1 0.34 0 0.8
80 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8
81 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
82 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
83 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78
84 INT296297 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Car2 1 0.01 0.59 0.77
85 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
86 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
87 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
88 INT170369 Binding of Car2 and Nono 1 0.01 0 0.76
89 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
90 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
91 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73
92 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73
93 INT255324 Negative_regulation of Binding of Dpep1 and 2E 1 0.02 0 0.73
94 INT136538 Nrgn Regulation of Car2 1 0.33 0 0.73
95 INT255325 Binding of Dpep1 and 2E 1 0.02 0 0.73
96 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
97 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
98 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71
99 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71
100 INT130356 Adcy10 Negative_regulation of Positive_regulation of Crp 1 0.13 0.23 0.71
101 INT297490 Itpr3 Regulation of Ltp 1 0.02 0 0.7
102 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
103 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
104 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
105 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 0.04 0.59 0.69
106 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
107 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68
108 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
109 INT48031 Binding of Oxt and Pebp1 1 0.01 0 0.68
110 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
111 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67
112 INT169217 Binding of Pebp1 and Coc 1 0.00 0.22 0.67
113 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67
114 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
115 INT261517 Binding of HTR2A and USH1C 1 0.01 0 0.66
116 INT220032 Nos1 Positive_regulation of Nos3 1 0.32 0.45 0.66
117 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
118 INT130357 Adcy10 Regulation of Fgg 1 0.03 0.2 0.66
119 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
120 INT334127 Acsm3 Positive_regulation of Vcam1 1 0.24 1.61 0.66
121 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65
122 INT308484 Car2 Positive_regulation of Pla2g4a 1 0.03 1.23 0.65
123 INT251165 Trpv1 Positive_regulation of Gene_expression of Ca2 1 0.15 0.54 0.65
124 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
125 INT356329 Crhr1 Regulation of Cea 1 0.09 0.31 0.64
126 INT65256 Pebp1 Regulation of Gene_expression of Basp1 1 0.00 0.05 0.64
127 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63
128 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
129 INT356314 Binding of Crhr1 and ORF61 1 0.00 0 0.63
130 INT2700 Binding of App and Cpe 1 0.00 0 0.63
131 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
132 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62
133 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
134 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
135 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
136 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
137 INT50816 Penk Positive_regulation of Localization of Ca2 1 0.32 0 0.62
138 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
139 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
140 INT255319 Binding of Dpep1 and Kcnq2 1 0.01 0 0.6
141 INT255320 Binding of Dpep1 and Kcnq3 1 0.01 0 0.6
142 INT92996 Binding of VCAM1 and GORASP1 1 0.39 0.33 0.6
143 INT255326 Binding of Dpep1 and AIS 1 0.00 0 0.6
144 INT70254 Binding of Htr1a and Ca2 1 0.31 0.5 0.6
145 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
146 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
147 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59
148 INT223865 Enpep Positive_regulation of Ltp 1 0.02 0 0.59
149 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 0.01 0 0.59
150 INT240070 KCNIP3 Regulation of CA2 1 0.02 0.72 0.59
151 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
152 INT92999 Binding of CD40 and VCAM1 1 0.39 0.33 0.57
153 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
154 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56
155 INT145718 Positive_regulation of Plat Positive_regulation of Bdnf 1 0.20 0 0.56
156 INT356321 Positive_regulation of Crhr1 Positive_regulation of Cea 1 0.19 0.37 0.56
157 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
158 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
159 INT356322 Positive_regulation of Crhr1 Positive_regulation of ORF61 1 0.00 0 0.54
160 INT209591 Car2 Positive_regulation of Positive_regulation of Ltp 1 0.05 0 0.54
161 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54
162 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
163 INT209592 Car2 Positive_regulation of Localization of Ltp 1 0.05 0 0.54
164 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
165 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
166 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
167 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53
168 INT118138 Binding of Ca2 and Mgat4a 1 0.01 0 0.53
169 INT139750 Ubqln1 Regulation of Dbh 1 0.00 0 0.52
170 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
171 INT130158 Pomc Regulation of Gene_expression of Crhr1 1 0.20 0 0.52
172 INT130163 Pomc Positive_regulation of Gene_expression of Crhr1 1 0.15 0 0.52
173 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
174 INT139751 Dbh Regulation of Localization of Prl 1 0.02 0 0.52
175 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52
176 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51
177 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
178 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
179 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
180 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51
181 INT333160 asa Negative_regulation of Gene_expression of Vcam1 1 0.19 0.71 0.5
182 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
183 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
184 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5
185 INT185800 SPP1 Negative_regulation of Gene_expression of MMP1 1 0.26 1.03 0.49
186 INT34006 Binding of ITPR3 and YY1 1 0.22 0.33 0.48
187 INT250077 Positive_regulation of Ltp Positive_regulation of Localization of Ca2 1 0.10 0 0.48
188 INT195192 Akr1d1 Regulation of Msn 1 0.01 0.34 0.47
189 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
190 INT136141 Hsd11b1 Positive_regulation of Gene_expression of Agrp 1 0.64 0.2 0.47
191 INT333161 asa Negative_regulation of Positive_regulation of Vcam1 1 0.22 0.57 0.47
192 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
193 INT261603 Il6 Regulation of Gene_expression of Vcam1 1 0.16 1.74 0.46
194 INT103025 Calca Positive_regulation of Nos3 1 0.25 0.41 0.46
195 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
196 INT103027 Ptgis Positive_regulation of Nos3 1 0.06 0.42 0.46
197 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
198 INT103030 Calca Positive_regulation of Positive_regulation of Nos3 1 0.26 0.41 0.46
199 INT237810 Itpr3 Positive_regulation of Localization of Car2 2 0.08 0.68 0.45
200 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45

Single Events

The table below shows the top 100 pain related interactions that have been reported for apical part of cell. They are ordered first by their pain relevance and then by number of times they were reported in apical part of cell. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64
2 INT65500 Gene_expression of App 605 0.78 429.94 98.31
3 INT4822 Localization of Ca2 417 0.80 99.57 96.45
4 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35
5 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71
6 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01
7 INT1032 Regulation of Ca2 202 0.52 54.91 53.03
8 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57
9 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76
10 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97
11 INT17561 Localization of Car2 303 0.79 60.95 44.52
12 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
13 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56
14 INT5489 Localization of CA2 172 0.80 39.46 33.56
15 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
16 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
17 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
18 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68
19 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26
20 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68
21 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
22 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96
23 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
24 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31
25 INT17962 Regulation of Car2 124 0.41 33.98 22.71
26 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86
27 INT3382 Positive_regulation of Dbh 33 0.70 11.64 21.67
28 INT112427 Positive_regulation of P2rx4 27 0.68 26.29 21.31
29 INT11625 Localization of App 98 0.78 55.46 20.86
30 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
31 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85
32 INT16794 Binding of App 103 0.48 64.87 19.79
33 INT65502 Regulation of App 77 0.62 52.05 19.44
34 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4
35 INT2960 Regulation of Dbh 32 0.47 10.32 18.94
36 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72
37 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71
38 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
39 INT4073 Localization of Dbh 28 0.81 6.06 16.37
40 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86
41 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
42 INT54052 Gene_expression of App 33 0.78 25.08 14.7
43 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07
44 INT82929 Gene_expression of Plat 58 0.78 26.96 13.85
45 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99
46 INT19799 Binding of Ca2 71 0.48 13.69 12.92
47 INT121242 Positive_regulation of Gene_expression of Nos3 37 0.69 31.96 12.71
48 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
49 INT29745 Binding of APP 47 0.48 26.49 12.4
50 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
51 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35
52 INT122053 Positive_regulation of P2rx4 16 0.69 13.02 11.98
53 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
54 INT119400 Phosphorylation of Car2 19 0.52 8.47 11.63
55 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61
56 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
57 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35
58 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24
59 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
60 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
61 INT3535 Regulation of CA2 61 0.32 16.48 10.8
62 INT98329 Gene_expression of P2RX4 23 0.75 13.13 10.25
63 INT29967 Positive_regulation of Positive_regulation of Car2 40 0.40 8.03 10.13
64 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07
65 INT33094 Regulation of Localization of Ca2 28 0.38 8.65 9.96
66 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84
67 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71
68 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71
69 INT112428 Positive_regulation of Gene_expression of P2rx4 12 0.68 12.67 9.57
70 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43
71 INT41569 Regulation of APP 32 0.62 17.15 9.4
72 INT168991 Negative_regulation of P2rx4 9 0.43 12.77 9.39
73 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35
74 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
75 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
76 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31
77 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
78 INT1129 Binding of Car2 69 0.35 14.01 9.2
79 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
80 INT163054 Gene_expression of Msn 20 0.66 0.6 9.06
81 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
82 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58
83 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45
84 INT31761 Positive_regulation of Itpr3 32 0.58 5.95 8.22
85 INT136177 Gene_expression of P2rx4 8 0.75 6.74 8.05
86 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01
87 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
88 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86
89 INT47546 Binding of Dbh 11 0.44 5.69 7.84
90 INT36040 Localization of Itpr3 21 0.70 4.87 7.77
91 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68
92 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64
93 INT65246 Negative_regulation of Nos3 36 0.50 25.65 7.62
94 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
95 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49
96 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
97 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
98 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
99 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
100 INT85764 Binding of PEBP1 9 0.44 4.52 7.2
101 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17
102 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88
103 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
104 INT64215 Gene_expression of Drd3 16 0.78 5.27 6.71
105 INT112430 Negative_regulation of P2rx4 9 0.57 8.4 6.63
106 INT19366 Negative_regulation of Localization of Ca2 33 0.50 6.51 6.61
107 INT33781 Binding of Pebp1 11 0.44 1.76 6.61
108 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59
109 INT9753 Positive_regulation of Localization of Crhr1 8 0.49 1.72 6.55
110 INT124488 Positive_regulation of Gene_expression of Plat 14 0.70 5.46 6.52
111 INT1280 Negative_regulation of Pebp1 7 0.28 2.12 6.45
112 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36
113 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35
114 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33
115 INT83712 Transcription of Nos3 19 0.69 13.09 6.31
116 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31
117 INT163052 Regulation of Msn 11 0.38 1.21 6.31
118 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3
119 INT127023 Negative_regulation of Gene_expression of Vcam1 24 0.59 20.39 6.28
120 INT42799 Positive_regulation of Drd3 11 0.69 1.1 5.92
121 INT26919 Gene_expression of ITPR3 47 0.42 5.86 5.79
122 INT124825 Transcription of Plat 8 0.70 3.15 5.68
123 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56
124 INT5490 Binding of CA2 52 0.36 9.73 5.53
125 INT149739 Regulation of Gene_expression of Ca2 25 0.38 7.22 5.53
126 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49
127 INT51411 Negative_regulation of EDAR 8 0.41 1.05 5.49
128 INT170516 Negative_regulation of Gene_expression of Car2 35 0.35 9.4 5.48
129 INT133638 Gene_expression of Dbh 9 0.78 1.23 5.46
130 INT22160 Negative_regulation of Positive_regulation of Car2 18 0.38 4.94 5.45
131 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
132 INT156134 Regulation of Gene_expression of Aqp1 5 0.59 7.2 5.3
133 INT215594 Negative_regulation of Gene_expression of P2rx4 7 0.48 6.46 5.22
134 INT107247 Regulation of Plat 10 0.44 7.21 5.14
135 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1
136 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
137 INT145681 Regulation of P2rx4 4 0.61 3.41 5.09
138 INT50330 Positive_regulation of Drd3 7 0.70 0.76 5.08
139 INT26334 Localization of ITPR3 39 0.49 2.53 5.07
140 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
141 INT6983 Negative_regulation of Positive_regulation of Ca2 18 0.41 4.29 5.03
142 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94
143 INT104668 Negative_regulation of Plat 27 0.49 17.18 4.83
144 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
145 INT131176 Gene_expression of Srr 8 0.64 3.29 4.81
146 INT18245 Negative_regulation of Localization of Crhr1 4 0.17 0.28 4.81
147 INT7568 Negative_regulation of Crhr1 8 0.43 4.63 4.77
148 INT75197 Gene_expression of Umod 3 0.75 2.48 4.75
149 INT24011 Binding of Drd3 13 0.47 3.03 4.64
150 INT158603 Positive_regulation of Gene_expression of P2RX4 7 0.55 5.85 4.56
151 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
152 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
153 INT139894 Negative_regulation of Msn 11 0.41 0.36 4.52
154 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41
155 INT208287 Binding of Msn 10 0.41 0.33 4.31
156 INT130083 Positive_regulation of Positive_regulation of Vcam1 8 0.36 5.81 4.31
157 INT136179 Positive_regulation of P2RX4 9 0.67 7.06 4.27
158 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24
159 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21
160 INT58003 Localization of APP 32 0.80 13.75 4.2
161 INT31762 Gene_expression of Itpr3 22 0.74 1.6 4.15
162 INT76714 Binding of Drd3 9 0.37 2.33 4.09
163 INT47298 Localization of Ctsl 13 0.79 3.77 4.08
164 INT325930 Gene_expression of Ezr 75 0.77 59.77 4.06
165 INT83991 Regulation of Nos3 25 0.44 9.89 4.06
166 INT97128 Localization of SPP1 32 0.80 21.75 4.02
167 INT102515 Binding of Nos3 19 0.45 9.41 4.01
168 INT188449 Gene_expression of ENPEP 12 0.55 11.29 3.96
169 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
170 INT131178 Positive_regulation of Srr 4 0.56 4.78 3.91
171 INT26191 Positive_regulation of ITPR3 24 0.44 1.9 3.74
172 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
173 INT85326 Positive_regulation of Aqp1 7 0.65 5.9 3.71
174 INT195187 Positive_regulation of Msn 5 0.49 0.38 3.66
175 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
176 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
177 INT89329 Regulation of Gene_expression of Drd3 4 0.61 0.72 3.56
178 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55
179 INT85537 Regulation of Crhr1 4 0.45 1.64 3.53
180 INT14068 Positive_regulation of Umod 4 0.49 2.3 3.53
181 INT104570 Localization of Aqp1 8 0.77 5.83 3.51
182 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
183 INT76468 Regulation of Positive_regulation of Car2 13 0.29 4.54 3.46
184 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
185 INT6405 Gene_expression of Enpep 9 0.67 4.79 3.4
186 INT5400 Positive_regulation of DBH 6 0.70 2.02 3.38
187 INT14625 Binding of Dpep1 2 0.02 0 3.36
188 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33
189 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33
190 INT21572 Gene_expression of Pebp1 9 0.71 2.52 3.3
191 INT70958 Binding of NOS3 19 0.37 11.84 3.29
192 INT37180 Negative_regulation of Itpr3 6 0.51 1.43 3.27
193 INT284848 Gene_expression of Pdzd2 23 0.74 1.36 3.25
194 INT127336 Positive_regulation of Transcription of Crhr1 3 0.48 3.37 3.19
195 INT15253 Binding of DBH 7 0.36 3.21 3.17
196 INT10517 Localization of Plat 16 0.47 8.44 3.11
197 INT54999 Regulation of Itpr3 6 0.24 0.18 3.11
198 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
199 INT88130 Gene_expression of Spp1 13 0.74 12.96 3.07
200 INT46291 Negative_regulation of Dbh 6 0.56 0.91 3.06
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