GO:0045184

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Name establishment of protein localization
Categary Process
Go Slim No
Go Link GO:0045184
Unique Molecular Interactions 262
Total Molecular Interactions 425
Total Single Events 2231
Pain Genes Associated 21

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for establishment of protein localization. They are ordered first by their pain relevance and then by number of times they were reported for establishment of protein localization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
4 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
5 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
6 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
7 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
8 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
9 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
10 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
11 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
12 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
13 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
14 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
15 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
16 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
17 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
18 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
19 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
20 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
21 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
22 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
23 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
24 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
25 INT120820 Binding of ASIC3 and Dlg4 3 0.02 0.11 0.84
26 INT155760 Binding of Nos1 and Dlg4 1 0.13 1.01 0.82
27 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
28 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
29 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
30 INT152944 Dlg4 Regulation of Gpr88 1 0.12 0.18 0.75
31 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
32 INT168205 Binding of Dlg4 and Pik3cd 1 0.11 0.37 0.65
33 INT296446 Binding of Gria2 and Gria4 1 0.13 0.55 0.57
34 INT343597 Gys1 Regulation of Transcription of Gria2 1 0.00 0 0.55
35 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
36 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
37 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
38 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
39 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
40 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54
41 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
42 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
43 INT205733 Gphn Regulation of Gene_expression of Gabrd 1 0.03 0.18 0.51
44 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
45 INT114676 Mdm2 Negative_regulation of p53-ps 1 0.10 0.26 0.48
46 INT263746 Binding of Dlg4 and Neto1 1 0.27 0 0.48
47 INT309370 Positive_regulation of Glyr1 Positive_regulation of Positive_regulation of Gphn 1 0.01 0 0.47
48 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
49 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
50 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42
51 INT135426 Binding of APBB1 and Dlg4 1 0.00 0.17 0.42
52 INT223870 Regulation of Gria2 Positive_regulation of Gene_expression of Ltp 1 0.01 0 0.4
53 INT334665 Ltp Regulation of Gria2 1 0.23 0.22 0.4
54 INT120821 Dlg4 Positive_regulation of ASIC3 1 0.02 0 0.36
55 INT272602 Binding of Dlg4 and Gria2 3 0.09 0.19 0.34
56 INT120817 Binding of Dlg4 and Lin7b 1 0.00 0 0.34
57 INT296465 Binding of Dlg4 and Rbm39 1 0.00 0.05 0.34
58 INT237633 Cntn1 Regulation of Gene_expression of Ank3 1 0.00 0.23 0.33
59 INT237637 Cntn1 Positive_regulation of Gene_expression of Ank3 1 0.00 0.23 0.33
60 INT354697 Positive_regulation of Binding of Gria2 and Pick1 1 0.08 0.73 0.33
61 INT283841 Dlg4 Negative_regulation of Insrr 1 0.01 0.95 0.33
62 INT237640 Nfasc Regulation of Gene_expression of Ank3 1 0.01 0.23 0.32
63 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
64 INT218842 Ppp1r9a Regulation of Gria2 1 0.19 0.87 0.32
65 INT237634 Nfasc Positive_regulation of Gene_expression of Ank3 1 0.02 0.23 0.32
66 INT198779 Binding of Dlg4 and Psd 10 0.25 0.09 0.31
67 INT296447 Pick1 Regulation of Gria2 1 0.16 0.49 0.3
68 INT218831 Ppp1cc Regulation of Gria2 1 0.27 0.86 0.3
69 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3
70 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
71 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
72 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
73 INT334670 Gria2 Regulation of Gene_expression of Gopc 1 0.31 0.27 0.29
74 INT334668 Gria2 Regulation of Gene_expression of Insrr 1 0.01 0.27 0.29
75 INT135425 Binding of Dlg4 and Dlg3 1 0.29 0.07 0.28
76 INT296448 Ush1c Regulation of Binding of Gria2 1 0.06 0.29 0.28
77 INT274944 Binding of Dlg4 and Pick1 1 0.04 0 0.28
78 INT334664 Negative_regulation of Gria2 Negative_regulation of Positive_regulation of Psmd1 1 0.19 1.17 0.27
79 INT296450 Cacng2 Regulation of Gria2 1 0.13 0.24 0.26
80 INT350835 Binding of SELS and Sels 1 0.16 1.24 0.26
81 INT274939 Binding of Dlg4 and Ephb6 1 0.12 0 0.25
82 INT296454 Camk2a Positive_regulation of Gene_expression of Gria2 1 0.30 0.14 0.24
83 INT190741 Adcyap1 Positive_regulation of Gria2 1 0.00 0 0.24
84 INT296443 Camk2a Positive_regulation of Gria2 1 0.28 0.14 0.24
85 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
86 INT263787 Binding of GRIN1 and Dlg4 3 0.18 0.05 0.23
87 INT198776 Binding of Dlg4 and Psds1 1 0.11 0.05 0.23
88 INT296474 Binding of Cacng2 and Gria2 1 0.18 0.26 0.23
89 INT287763 Binding of Gria2 and Ap3m1 1 0.02 0.33 0.21
90 INT237642 Binding of Ank3 and Nfasc 1 0.02 0 0.2
91 INT273099 Bdnf Positive_regulation of Localization of Dlg4 1 0.21 0.07 0.18
92 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
93 INT287764 Binding of Gria2 and Nsf 1 0.34 0.33 0.18
94 INT157557 Binding of Gria2 and Nrf1 1 0.11 0 0.17
95 INT250052 Prkaca Regulation of Gria2 1 0.05 0 0.17
96 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
97 INT351759 Gria2 Regulation of Car2 1 0.07 0.4 0.17
98 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
99 INT261518 Binding of DLG4 and HTR4 1 0.01 0 0.16
100 INT296469 Gene_expression of Cacng2 Positive_regulation of Gria2 1 0.15 0 0.16
101 INT354968 Shank3 Positive_regulation of Gene_expression of Gria2 1 0.05 0 0.15
102 INT244045 Binding of Arhgef9 and Gphn 1 0.02 0.2 0.15
103 INT261520 Binding of DLG4 and HTR2A 1 0.06 0 0.14
104 INT272605 Binding of Dlg4 and Nsf 1 0.36 0.41 0.14
105 INT244059 Binding of Gabarap and Gphn 1 0.05 0.05 0.13
106 INT354705 Binding of ASIC2 and Dlg4 1 0.00 0.11 0.12
107 INT101231 Positive_regulation of Gria2 Positive_regulation of Binding of Mlst8 1 0.06 0 0.12
108 INT101232 Gria2 Positive_regulation of P9Ehs1 1 0.04 0 0.12
109 INT260497 VEGFA Positive_regulation of Gria2 1 0.03 1.08 0.12
110 INT171792 GPER Regulation of Gene_expression of Itga2 1 0.00 0.54 0.12
111 INT354698 Binding of Dlg4 and Gopc 1 0.02 0.11 0.12
112 INT170368 Positive_regulation of Camk2a Positive_regulation of Regulation of Gria2 1 0.06 0 0.11
113 INT244013 Gphn Positive_regulation of Gabrg1 1 0.07 0 0.11
114 INT354717 Binding of ASIC1 and Dlg4 1 0.02 0 0.11
115 INT296468 Cacng2 Regulation of Regulation of Gria2 1 0.10 0 0.11
116 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
117 INT273108 Gria1 Regulation of Positive_regulation of Gria2 1 0.04 0.09 0.1
118 INT244039 Binding of Gabrg1 and Gphn 1 0.09 0.16 0.1
119 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1
120 INT272265 Binding of Dlg4 and Grip2 1 0.02 0 0.09
121 INT190746 Positive_regulation of Gria2 Positive_regulation of Car2 1 0.00 0.13 0.09
122 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
123 INT190742 Adcyap1 Regulation of Gria2 1 0.00 0 0.08
124 INT265256 Binding of Gria2 and Cdh2 2 0.02 0.17 0.07
125 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
126 INT263764 Dlg4 Regulation of Localization of Grin2a 1 0.16 0.17 0.07
127 INT263741 Grin2b Regulation of Localization of Dlg4 1 0.17 0.17 0.07
128 INT263784 Dlg4 Regulation of Localization of Grin1 1 0.17 0.17 0.07
129 INT263748 Grin1 Regulation of Localization of Gria2 1 0.20 0.17 0.07
130 INT272595 Binding of Dlg4 and Dnahc8 1 0.03 0.21 0.07
131 INT263723 Grin2b Regulation of Localization of Gria2 1 0.18 0.17 0.07
132 INT263734 Dlg4 Regulation of Localization of Vamp2 1 0.15 0.17 0.07
133 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
134 INT263742 Grin1 Regulation of Localization of Dlg4 1 0.19 0.17 0.07
135 INT244022 Binding of Nrxn1 and Nlgn4l 1 0.00 0.21 0.07
136 INT263772 Grin2a Regulation of Localization of Gria2 1 0.19 0.17 0.07
137 INT263771 Grin2a Regulation of Localization of Dlg4 1 0.19 0.17 0.07
138 INT263722 Dlg4 Regulation of Localization of Grin2b 1 0.15 0.17 0.07
139 INT351760 Adarb1 Regulation of Gria2 1 0.30 1.7 0.07
140 INT193790 ITIH4 Regulation of Gene_expression of MDM2 1 0.06 0.45 0.07
141 INT263740 Dlg4 Regulation of Localization of Gria2 1 0.11 0.17 0.07
142 INT263724 Positive_regulation of Binding of Dlg4 and Neto1 1 0.28 0 0.06
143 INT346754 Binding of Dlg4 and Gria2 1 0.02 0 0.06
144 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
145 INT263751 Binding of Dlg4 and Spna1 1 0.03 0 0.05
146 INT350823 Binding of SAA1 and SELS 1 0.17 2.75 0.05
147 INT263778 Localization of Neto1 Regulation of Localization of Dlg4 1 0.26 0.18 0.05
148 INT263733 Localization of Neto1 Regulation of Localization of Gria2 1 0.26 0.18 0.05
149 INT272598 Dlg4 Positive_regulation of Gene_expression of Gria2 1 0.03 0.53 0.04
150 INT272593 Dlg4 Positive_regulation of Clc 1 0.11 0.54 0.04
151 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
152 INT272591 Dlg4 Positive_regulation of Gene_expression of Clybl 1 0.09 0.53 0.04
153 INT272590 Dlg4 Positive_regulation of Clybl 1 0.09 0.52 0.04
154 INT246786 Ogg1 Regulation of Phosphorylation of Tsc2 1 0.20 0.42 0.04
155 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
156 INT272599 Dlg4 Positive_regulation of Gene_expression of Clc 1 0.11 0.54 0.04
157 INT354965 Binding of Gria2 and Sh3 1 0.01 0 0.04
158 INT272603 Binding of Dlg4 and Nlgn2 1 0.23 0 0.03
159 INT272600 Binding of Dlg4 and Grik5 1 0.20 0 0.03
160 INT272597 Binding of Dlg4 and Kcna4 1 0.17 0 0.03
161 INT263788 Positive_regulation of Binding of GRIN1 and Dlg4 1 0.24 0 0.03
162 INT272596 Binding of Dlg4 and Lrp1 1 0.16 0 0.03
163 INT246791 Tsc2 Regulation of Ogg1 1 0.27 0.56 0.03
164 INT272606 Binding of Dlg4 and Grin2c 1 0.18 0 0.03
165 INT272604 Binding of Dlg4 and Nlgn3 1 0.17 0 0.03
166 INT272601 Binding of Dlg4 and Grik2 1 0.22 0 0.03
167 INT272594 Binding of Dlg4 and Shank1 1 0.20 0 0.03
168 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
169 INT272609 Binding of Cit and Dlg4 1 0.11 0 0.03
170 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
171 INT198780 Regulation of Binding of Dlg4 and Psd 1 0.14 0 0.03
172 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
173 INT346742 Binding of Cacng2 and Dlg4 1 0.03 0 0
174 INT246784 Negative_regulation of Tsc2 Positive_regulation of Negative_regulation of Ogg1 1 0.20 0.43 0
175 INT314746 Akt1 Positive_regulation of Phosphorylation of MDM2 1 0.32 1.16 0
176 INT263791 Binding of DLG3 and Dlg4 1 0.20 0 0
177 INT272592 Binding of Dlg4 and Sh3 1 0.11 0.13 0
178 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 0.05 0.06 0
179 INT246811 Ros1 Positive_regulation of Tsc2 1 0.02 0 0
180 INT263726 Binding of Dlg1 and Dlg4 1 0.04 0 0
181 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
182 INT246794 Ros1 Positive_regulation of Phosphorylation of Tsc2 1 0.03 0.66 0
183 INT338018 Binding of AR and Flna 1 0.11 0.33 0
184 INT331089 Binding of Cd3e and Itga2 1 0.09 0.2 0
185 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0
186 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
187 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
188 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
189 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
190 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
191 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
192 INT246787 Akt2 Positive_regulation of Phosphorylation of Tsc2 1 0.10 0.16 0
193 INT350822 SELS Positive_regulation of Gene_expression of SAA1 1 0.21 0.87 0
194 INT246789 Pik3c3 Regulation of Tsc2 1 0.02 0.34 0
195 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
196 INT272610 Binding of NA and Dlg4 1 0.41 0.13 0
197 INT246809 Negative_regulation of Tsc2 Positive_regulation of Positive_regulation of Ogg1 1 0.20 0.45 0
198 INT265258 Positive_regulation of gr Regulation of Gria2 1 0.01 0 0
199 INT346746 Binding of Cacng2 and Gria2 1 0.21 0.18 0
200 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for establishment of protein localization. They are ordered first by their pain relevance and then by number of times they were reported in establishment of protein localization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221172 Binding of Flna 32 0.42 1.37 51.59
2 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
3 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
4 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
5 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
6 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
7 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
8 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
9 INT97100 Negative_regulation of Dlg4 16 0.58 6.18 14.36
10 INT88789 Gene_expression of Dlg4 26 0.78 4.41 12.74
11 INT114674 Gene_expression of Mdm2 15 0.78 3.51 11.85
12 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
13 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
14 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
15 INT115614 Binding of Gria2 25 0.43 8.97 9.91
16 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
17 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
18 INT108643 Gene_expression of Dlg4 61 0.76 8.63 8.58
19 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
20 INT63852 Gene_expression of Gphn 21 0.63 5.64 8.2
21 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
22 INT114675 Positive_regulation of Gene_expression of Mdm2 1 0.70 1.98 7.9
23 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
24 INT97099 Positive_regulation of Dlg4 13 0.60 3.04 6.98
25 INT88786 Binding of Dlg4 11 0.46 2.73 6.58
26 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55
27 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
28 INT135998 Localization of Gria2 18 0.72 3.14 5.15
29 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
30 INT85946 Localization of Gria2 10 0.61 1.23 5.09
31 INT26042 Binding of Gria2 20 0.40 4.88 5.04
32 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
33 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
34 INT88790 Negative_regulation of Gene_expression of Dlg4 6 0.59 1.53 4.66
35 INT145532 Localization of Dlg4 25 0.79 1.97 4.36
36 INT39948 Binding of FLNA 45 0.42 58.05 4.27
37 INT88787 Transcription of Dlg4 4 0.69 0.83 4.09
38 INT221168 Localization of Flna 1 0.58 0.05 4.05
39 INT120810 Binding of Dlg4 38 0.41 3.55 4.03
40 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
41 INT170351 Positive_regulation of Gene_expression of Gria2 13 0.67 3.67 3.27
42 INT250581 Gene_expression of SELS 4 0.78 47.37 3.27
43 INT94688 Negative_regulation of Gphn 4 0.21 2.35 2.95
44 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
45 INT114513 Negative_regulation of Gene_expression of Gria2 8 0.48 0.89 2.61
46 INT89830 Positive_regulation of Gphn 4 0.45 0.81 2.61
47 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
48 INT46646 Localization of FLNA 19 0.73 18.83 2.53
49 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
50 INT153733 Negative_regulation of Transcription of Gria2 1 0.47 0 2.39
51 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
52 INT281073 Negative_regulation of Gene_expression of Gria2 4 0.56 0.72 2.18
53 INT101229 Positive_regulation of Positive_regulation of Gria2 5 0.41 2.2 2.16
54 INT134874 Regulation of Dlg4 3 0.58 0.28 2.12
55 INT221179 Regulation of Flna 1 0.24 0.13 2.04
56 INT259164 Positive_regulation of Binding of Gria2 4 0.40 2 1.91
57 INT143277 Regulation of Phosphorylation of Gria2 5 0.60 1.91 1.87
58 INT198748 Regulation of Gene_expression of Dlg4 10 0.44 2.16 1.85
59 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
60 INT114508 Positive_regulation of Negative_regulation of Gria2 2 0.36 0.98 1.64
61 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
62 INT119219 Localization of Dlg4 3 0.64 0.16 1.5
63 INT152939 Regulation of Dlg4 9 0.60 1.09 1.49
64 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
65 INT218807 Transcription of Gria2 6 0.69 3.08 1.46
66 INT134873 Phosphorylation of Dlg4 3 0.80 0.5 1.42
67 INT114671 Positive_regulation of Mdm2 1 0.61 0.5 1.38
68 INT97098 Regulation of Negative_regulation of Dlg4 3 0.45 0.97 1.3
69 INT63845 Regulation of Gene_expression of Gphn 5 0.36 0.23 1.23
70 INT162222 Positive_regulation of Positive_regulation of Gria2 3 0.38 0.64 1.19
71 INT243982 Gene_expression of Gphn 13 0.63 1.39 1.09
72 INT257210 Positive_regulation of Phosphorylation of Gria2 3 0.41 0.65 1.07
73 INT198750 Positive_regulation of Gene_expression of Dlg4 5 0.68 0.6 1.02
74 INT114673 Regulation of Gene_expression of Mdm2 1 0.62 0.23 1.02
75 INT72990 Binding of Gphn 4 0.25 0.34 0.94
76 INT134876 Negative_regulation of Phosphorylation of Dlg4 1 0.35 0.27 0.93
77 INT134878 Negative_regulation of Negative_regulation of Dlg4 1 0.35 0.27 0.93
78 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
79 INT243977 Positive_regulation of Gene_expression of Gphn 3 0.41 0.11 0.83
80 INT157555 Positive_regulation of Regulation of Gria2 2 0.28 0.26 0.82
81 INT72992 Transcription of Gphn 3 0.50 0.19 0.8
82 INT169844 Positive_regulation of Localization of Dlg4 2 0.49 0.07 0.75
83 INT218805 Negative_regulation of Phosphorylation of Gria2 2 0.38 1.51 0.73
84 INT353369 Regulation of Localization of Dlg4 1 0.23 0 0.69
85 INT252054 Phosphorylation of TSC2 4 0.80 0.63 0.67
86 INT156376 Negative_regulation of Transcription of Dlg4 1 0.56 0.16 0.65
87 INT99750 Localization of Gphn 2 0.73 1.28 0.63
88 INT162221 Positive_regulation of Localization of Gria2 2 0.38 0.09 0.61
89 INT349122 Regulation of Phosphorylation of Gria2 1 0.28 0.57 0.61
90 INT259166 Protein_catabolism of Gria2 2 0.70 0.47 0.58
91 INT95932 Negative_regulation of Negative_regulation of Gria2 3 0.35 0.75 0.56
92 INT198749 Negative_regulation of Dlg4 8 0.53 2.14 0.54
93 INT198744 Negative_regulation of Gene_expression of Dlg4 6 0.42 1.73 0.54
94 INT243864 Gene_expression of DLG4 5 0.34 0.22 0.54
95 INT118891 Transcription of Itga2 1 0.03 0 0.54
96 INT153321 Positive_regulation of Gene_expression of Dlg4 3 0.49 0.31 0.53
97 INT243949 Positive_regulation of Gphn 3 0.41 0.29 0.52
98 INT156377 Regulation of Binding of Dlg4 1 0.43 0.17 0.51
99 INT230982 Positive_regulation of Transcription of Gria2 1 0.28 0.65 0.51
100 INT198755 Positive_regulation of Dlg4 7 0.59 0.6 0.5
101 INT296431 Negative_regulation of Binding of Gria2 1 0.38 0.6 0.5
102 INT15047 Negative_regulation of SELS 1 0.35 0.34 0.49
103 INT296434 Regulation of Regulation of Gria2 1 0.40 0.43 0.49
104 INT218813 Positive_regulation of Transcription of Gria2 1 0.39 1.19 0.48
105 INT89829 Positive_regulation of Positive_regulation of Gphn 1 0.00 0.29 0.47
106 INT309338 Positive_regulation of Positive_regulation of Gphn 1 0.09 0 0.44
107 INT250047 Positive_regulation of Localization of Gria2 2 0.41 0.44 0.43
108 INT349121 Negative_regulation of Binding of Gria2 1 0.22 0.59 0.43
109 INT296439 Negative_regulation of Localization of Gria2 2 0.41 0.1 0.41
110 INT114512 Positive_regulation of Regulation of Gria2 1 0.33 0 0.41
111 INT100254 Binding of SELS 6 0.36 4.54 0.4
112 INT237625 Gene_expression of Ank3 2 0.53 0.38 0.4
113 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
114 INT351452 Negative_regulation of Positive_regulation of Gria2 1 0.26 0.64 0.39
115 INT72991 Regulation of Gphn 4 0.22 0.34 0.38
116 INT221178 Positive_regulation of Gene_expression of Flna 1 0.39 0 0.38
117 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
118 INT177394 Positive_regulation of Binding of Gria2 2 0.45 1.18 0.36
119 INT243956 Negative_regulation of Gphn 3 0.35 0.94 0.35
120 INT221833 Positive_regulation of TSC2 2 0.23 0.39 0.33
121 INT239861 Gene_expression of Itga2 5 0.65 1.32 0.32
122 INT26173 Regulation of SELS 3 0.52 3.4 0.32
123 INT296258 Negative_regulation of Localization of Dlg4 1 0.32 0 0.32
124 INT350833 Positive_regulation of Gene_expression of SELS 1 0.61 6.07 0.32
125 INT172957 Negative_regulation of Mdm2 4 0.14 4.28 0.3
126 INT140187 Positive_regulation of Itga2 1 0.18 0.34 0.3
127 INT239863 Negative_regulation of Gene_expression of Itga2 1 0.03 0.8 0.29
128 INT171788 Positive_regulation of Binding of Itga2 1 0.02 0.94 0.28
129 INT171790 Regulation of Binding of Itga2 1 0.01 0.93 0.28
130 INT171789 Binding of Itga2 1 0.02 0.92 0.27
131 INT215979 Binding of Gphn 4 0.34 0.77 0.26
132 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26
133 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25
134 INT72994 Localization of Gphn 2 0.51 0 0.23
135 INT320581 Positive_regulation of Gene_expression of Gphn 1 0.34 0 0.23
136 INT237618 Localization of Ank3 2 0.55 0.4 0.22
137 INT296435 Regulation of Binding of Gria2 1 0.55 0.5 0.22
138 INT154360 Localization of Tsc2 1 0.56 0.16 0.22
139 INT305975 Regulation of Gene_expression of SELS 2 0.60 3.19 0.21
140 INT167250 Regulation of Gene_expression of MDM2 1 0.06 0.86 0.21
141 INT88744 Positive_regulation of Gene_expression of MDM2 9 0.43 7.82 0.2
142 INT172958 Positive_regulation of Mdm2 4 0.56 2.43 0.19
143 INT350827 Localization of SELS 1 0.62 1.24 0.19
144 INT272255 Regulation of Positive_regulation of Dlg4 1 0.39 0.06 0.19
145 INT243875 Positive_regulation of Gene_expression of DLG4 1 0.30 0.22 0.19
146 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
147 INT272253 Negative_regulation of Regulation of Dlg4 1 0.37 0 0.18
148 INT157556 Negative_regulation of Positive_regulation of Gria2 1 0.24 0 0.18
149 INT305978 Protein_catabolism of SELS 1 0.86 0.88 0.17
150 INT126733 Regulation of MDM2 2 0.36 0.73 0.16
151 INT113346 Binding of MDM2 10 0.35 5.73 0.15
152 INT266010 Localization of Mdm2 2 0.75 2.64 0.15
153 INT204054 Negative_regulation of Negative_regulation of Mdm2 2 0.14 2.23 0.15
154 INT286764 Regulation of Localization of Mdm2 1 0.14 1.38 0.15
155 INT286748 Regulation of Mdm2 1 0.14 1.37 0.15
156 INT243883 Negative_regulation of DLG4 1 0.19 0.07 0.15
157 INT175517 Gene_expression of Mdm2 18 0.78 16.28 0.13
158 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13
159 INT119228 Gene_expression of TSC2 3 0.75 4.43 0.13
160 INT350834 Transcription of SELS 1 0.53 4.8 0.13
161 INT350832 Positive_regulation of Transcription of SELS 1 0.41 1 0.13
162 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12
163 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12
164 INT198738 Protein_catabolism of Dlg4 5 0.97 0.06 0.12
165 INT243962 Negative_regulation of Gene_expression of Gphn 1 0.13 0.13 0.12
166 INT115521 Gene_expression of Itga2 1 0.04 0.62 0.12
167 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
168 INT271941 Binding of Tsc2 12 0.24 2.96 0.11
169 INT72993 Regulation of Localization of Gphn 1 0.09 0 0.11
170 INT311132 Regulation of Regulation of Gphn 1 0.22 0.34 0.11
171 INT250570 Negative_regulation of Gene_expression of SELS 2 0.43 2.85 0.1
172 INT115520 Regulation of Itga2 2 0.01 0.46 0.1
173 INT254015 Positive_regulation of Ank3 1 0.34 0 0.1
174 INT272257 Positive_regulation of Localization of Dlg4 1 0.43 0 0.1
175 INT246772 Regulation of Phosphorylation of Tsc2 1 0.26 1.37 0.09
176 INT283601 Negative_regulation of Localization of Gphn 1 0.30 0.33 0.08
177 INT305385 Negative_regulation of Localization of FLNA 1 0.16 0.79 0.08
178 INT160809 Negative_regulation of Negative_regulation of Gria2 1 0.03 0 0.08
179 INT156437 Binding of DLG4 2 0.35 0.29 0.07
180 INT243988 Binding of Nrxn1 1 0.01 0.21 0.07
181 INT243932 Gene_expression of Nrxn1 1 0.02 0.28 0.06
182 INT246770 Positive_regulation of Negative_regulation of Tsc2 1 0.20 1.91 0.05
183 INT100988 Regulation of Gene_expression of Dlg4 1 0.36 0.06 0.05
184 INT178278 Regulation of Positive_regulation of FLNA 1 0.04 0.4 0.05
185 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04
186 INT242338 Binding of TSC2 2 0.22 1.56 0.04
187 INT287282 Regulation of Binding of MDM2 1 0.04 0.63 0.04
188 INT254014 Regulation of Gene_expression of Ank3 1 0.31 0 0.04
189 INT198746 Regulation of Protein_catabolism of Dlg4 1 0.26 0 0.04
190 INT283603 Regulation of Gene_expression of Gphn 1 0.37 0.17 0.04
191 INT272252 Regulation of Phosphorylation of Dlg4 1 0.44 0 0.04
192 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04
193 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03
194 INT236523 Binding of Flna 3 0.30 0.45 0.03
195 INT176240 Phosphorylation of Mdm2 2 0.22 1.28 0.03
196 INT176252 Positive_regulation of Phosphorylation of Mdm2 1 0.14 0.42 0.03
197 INT126734 Positive_regulation of MDM2 8 0.49 5.56 0
198 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0
199 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0
200 INT228895 Binding of Tsc2 5 0.30 2.41 0
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