GO:0045294

From wiki-pain
Jump to: navigation, search
Name alpha-catenin binding
Categary Function
Go Slim No
Go Link GO:0045294
Unique Molecular Interactions 79
Total Molecular Interactions 95
Total Single Events 605
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for alpha-catenin binding. They are ordered first by their pain relevance and then by number of times they were reported for alpha-catenin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
2 INT122107 Plbd2 Negative_regulation of Cdh2 1 0.03 0.42 0.5
3 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
4 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
5 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
6 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
7 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
8 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
9 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
10 INT141257 Binding of S100A8 and VCL 1 0.36 0.97 0.09
11 INT265256 Binding of Gria2 and Cdh2 2 0.02 0.17 0.07
12 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
13 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
14 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
15 INT141256 S100A8 Positive_regulation of VCL 1 0.50 0.99 0.06
16 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
17 INT141258 S100A8 Negative_regulation of VCL 1 0.43 0.99 0.06
18 INT251373 Binding of Cdh2 and Cdh1 1 0.17 0 0.04
19 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
20 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
21 INT251370 Cdh2 Regulation of Gene_expression of Cdh1 1 0.21 0.35 0
22 INT222140 Binding of Cdh2 and Synm 1 0.00 0 0
23 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
24 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
25 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0
26 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
27 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
28 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
29 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
30 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
31 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
32 INT346756 Binding of Cdh2 and Grip2 1 0.00 0.1 0
33 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0
34 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
35 INT234970 Binding of Jup and Lat 1 0.01 0 0
36 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
37 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
38 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0
39 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
40 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
41 INT251372 Cdh1 Regulation of Gene_expression of Cdh2 1 0.21 0.35 0
42 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
43 INT234982 Binding of Jup and Pkp1 1 0.00 0 0
44 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for alpha-catenin binding. They are ordered first by their pain relevance and then by number of times they were reported in alpha-catenin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
2 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
3 INT111944 Phosphorylation of VCL 3 0.73 5.23 1.72
4 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
5 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
6 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
7 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
8 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
9 INT122106 Localization of Cdh2 3 0.69 0.95 1
10 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
11 INT111941 Regulation of Phosphorylation of VCL 1 0.27 0.66 0.8
12 INT111942 Positive_regulation of Phosphorylation of VCL 1 0.30 0.67 0.8
13 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
14 INT122104 Regulation of Localization of Cdh2 1 0.23 0.51 0.62
15 INT222133 Gene_expression of Cdh2 32 0.61 4.81 0.58
16 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
17 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
18 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
19 INT242168 Transcription of JUP 4 0.67 1.17 0.46
20 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
21 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
22 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
23 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
24 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
25 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
26 INT226835 Gene_expression of Cdh2 14 0.22 8.04 0.31
27 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
28 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
29 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
30 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
31 INT173653 Positive_regulation of CDH2 3 0.06 1.77 0.18
32 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
33 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
34 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
35 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
36 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
37 INT259168 Positive_regulation of Gene_expression of Cdh2 1 0.11 0.12 0.13
38 INT251367 Binding of Cdh2 3 0.38 0.19 0.09
39 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
40 INT309877 Localization of JUP 2 0.73 1.38 0.08
41 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
42 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
43 INT141261 Negative_regulation of VCL 1 0.45 0.95 0.07
44 INT251360 Negative_regulation of Gene_expression of Cdh2 1 0.33 0 0.07
45 INT234866 Regulation of Jup 2 0.08 0.58 0.06
46 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
47 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
48 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
49 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
50 INT263798 Gene_expression of VCL 1 0.18 1.14 0.05
51 INT201818 Regulation of CDH2 3 0.09 1.89 0.04
52 INT247803 Positive_regulation of Cdh2 2 0.11 2.03 0.04
53 INT251363 Transcription of Cdh2 1 0.54 0 0.04
54 INT247791 Localization of Cdh2 4 0.22 0.96 0.03
55 INT251358 Positive_regulation of Cdh2 3 0.54 0.97 0.03
56 INT286533 Negative_regulation of Gene_expression of Cdh2 1 0.11 1.4 0.03
57 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
58 INT234867 Localization of Jup 1 0.24 2.84 0.03
59 INT175651 Gene_expression of CDH2 5 0.36 2.59 0
60 INT201814 Negative_regulation of CDH2 4 0.20 0.25 0
61 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
62 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
63 INT221539 Regulation of Cdh2 2 0.06 0.38 0
64 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
65 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
66 INT221864 Binding of JUP 2 0.36 1.05 0
67 INT221859 Binding of Jup 2 0.14 2.21 0
68 INT173646 Binding of CDH2 1 0.05 0.23 0
69 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
70 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
71 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
72 INT221537 Binding of Cdh2 1 0.09 0 0
73 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
74 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
75 INT247796 Regulation of Gene_expression of Cdh2 1 0.06 0.39 0
76 INT201811 Negative_regulation of Gene_expression of CDH2 1 0.12 0.09 0
77 INT286541 Negative_regulation of Cdh2 1 0.03 1.09 0
78 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
79 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
80 INT309972 Negative_regulation of Cdh2 1 0.13 0.9 0
81 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
82 INT251366 Regulation of Cdh2 1 0.48 0.34 0
83 INT251365 Regulation of Gene_expression of Cdh2 1 0.35 0.35 0
84 INT309876 Regulation of JUP 1 0.60 0.67 0
85 INT286559 Positive_regulation of Gene_expression of Cdh2 1 0.04 1.04 0
86 INT221575 Regulation of Binding of Cdh2 1 0.11 0 0
87 INT283878 Localization of VCL 1 0.19 1.12 0
88 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
89 INT201805 Negative_regulation of Negative_regulation of CDH2 1 0.09 0.25 0
90 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
91 INT175643 Positive_regulation of Gene_expression of CDH2 1 0.04 1.11 0
92 INT307737 Binding of VCL 1 0.13 0.36 0
93 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0
94 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox