GO:0045334

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Name clathrin-coated endocytic vesicle
Categary Component
Go Slim No
Go Link GO:0045334
Unique Molecular Interactions 111
Total Molecular Interactions 230
Total Single Events 788
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for clathrin-coated endocytic vesicle. They are ordered first by their pain relevance and then by number of times they were reported for clathrin-coated endocytic vesicle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
3 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
4 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
5 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
6 INT165200 Binding of CTLA4 and Crp 1 0.09 1.64 1.91
7 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
8 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
9 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
10 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
11 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
12 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
13 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
14 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
15 INT18828 DNM2 Positive_regulation of Localization of LTB4R 1 0.01 0.07 1.06
16 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
17 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
18 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
19 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
20 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85
21 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
22 INT133943 Binding of DNM2 and OPRL1 1 0.00 0 0.73
23 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
24 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72
25 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72
26 INT139069 Binding of CTLA4 and Cd86 3 0.16 0.65 0.7
27 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
28 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69
29 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
30 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
31 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
32 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
33 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
34 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
35 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
36 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
37 INT76002 Ngf Positive_regulation of Ngfr 1 0.05 0.48 0.53
38 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
39 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
40 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
41 INT120295 Ngf Positive_regulation of Positive_regulation of Ngfr 1 0.47 0.22 0.43
42 INT157657 Binding of CTLA4 and FCGR1A 1 0.01 0.07 0.4
43 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
44 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
45 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37
46 INT73536 Ngf Regulation of Ngfr 1 0.22 0.08 0.37
47 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
48 INT112283 Bdnf Regulation of Gene_expression of Ngfr 1 0.14 0.28 0.34
49 INT139068 Binding of CTLA4 and Cd80 1 0.00 0.33 0.33
50 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32
51 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32
52 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32
53 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28
54 INT333549 Binding of CTLA4 and PDCD1 1 0.36 1.2 0.27
55 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22
56 INT241451 Mag Positive_regulation of Ngfr 1 0.09 0.1 0.21
57 INT308654 Binding of Ngfr and Nts 1 0.06 0.39 0.21
58 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18
59 INT252367 Binding of RUNX1 and CTLA4 1 0.02 0.48 0.18
60 INT280486 Binding of Ngfr and Ntrk2 2 0.18 1.21 0.17
61 INT125770 GLP1R Negative_regulation of Localization of GCG 2 0.29 0.65 0.16
62 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16
63 INT241462 Binding of OMG and Ngfr 1 0.11 0.15 0.15
64 INT241457 Binding of Mag and Ngfr 1 0.09 0.15 0.15
65 INT241453 Binding of Ngfr and Rtn4r 1 0.03 0.15 0.15
66 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
67 INT349858 Binding of Ngfr and Ntrk2 1 0.09 0.32 0.11
68 INT314625 Ex Positive_regulation of GLP1R 1 0.03 0.3 0.11
69 INT280493 Ngfr Regulation of Protein_catabolism of BDNF 1 0.09 0.14 0.1
70 INT242203 GLP1R Regulation of GCG 1 0.04 0.64 0.1
71 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1
72 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09
73 INT145987 Binding of CTLA4 and Aip 1 0.08 0.61 0.09
74 INT164675 Binding of NGF and Ngfr 1 0.00 0.5 0.08
75 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08
76 INT164676 Negative_regulation of Binding of NGF and Ngfr 1 0.00 0.5 0.08
77 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06
78 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
79 INT248945 Ctla4 Regulation of Gene_expression of Cd4 1 0.18 0 0.04
80 INT241449 Mag Positive_regulation of Protein_catabolism of Ngfr 1 0.09 0 0.03
81 INT299450 Foxl2 Regulation of Ctla4 1 0.24 0.35 0.03
82 INT299442 Foxl2 Regulation of Transcription of Ctla4 1 0.24 0.35 0.03
83 INT201732 Ngfr Positive_regulation of Nfkb1 1 0.01 0.43 0.03
84 INT200063 Binding of MAGED1 and Ngfr 1 0.44 0.45 0
85 INT311223 GLP1R Regulation of Localization of GCG 1 0.16 0.74 0
86 INT125769 GLP1R Regulation of INS 1 0.44 0.7 0
87 INT265217 Negative_regulation of Binding of Ctla4 and Cd86 1 0.15 0.14 0
88 INT338013 Binding of Ngfrap1 and Ngfr 1 0.06 1.3 0
89 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
90 INT255024 DPP4 Negative_regulation of Protein_catabolism of GLP1R 1 0.14 0.78 0
91 INT200053 Binding of Nuc and Ngfr 1 0.10 0.3 0
92 INT200057 Binding of Ndn and Ngfr 1 0.43 1.96 0
93 INT320346 Binding of Ngfr and Np4 1 0.01 0 0
94 INT313572 GLP1R Negative_regulation of GCG 1 0.29 0.54 0
95 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0
96 INT325838 Binding of Dnm1 and Dnm2 1 0.50 0.05 0
97 INT125768 Positive_regulation of GLP1R Regulation of INS 1 0.48 0.71 0
98 INT201742 Binding of Ngfr and Gtf3a 1 0.00 0.77 0
99 INT265223 Negative_regulation of Binding of Ctla4 and Cd28 1 0.18 0.14 0
100 INT200061 Binding of Ngfr and Fez1 1 0.31 0.3 0
101 INT255025 Positive_regulation of GLP1R Positive_regulation of Localization of INS 1 0.17 0.12 0
102 INT255043 DPP4 Positive_regulation of GLP1R 1 0.35 0.32 0
103 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
104 INT201741 Binding of Rhoa and Ngfr 1 0.01 1 0
105 INT237354 Binding of DNM2 and Bin1 1 0.40 1.22 0
106 INT149120 Binding of CTLA4 and Cd28 1 0.03 0.14 0
107 INT227773 Ctla4 Negative_regulation of Binding of Cd80 1 0.01 0.11 0
108 INT200055 Binding of Ngfr and Mageh1 1 0.33 0.45 0
109 INT325836 Binding of Dnm2 and Gnas 1 0.00 0.22 0
110 INT348644 Binding of DPP4 and GLP1R 1 0.16 0.5 0
111 INT255042 Negative_regulation of DPP4 Positive_regulation of GLP1R 1 0.33 0.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for clathrin-coated endocytic vesicle. They are ordered first by their pain relevance and then by number of times they were reported in clathrin-coated endocytic vesicle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
2 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
3 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07
4 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
5 INT91357 Regulation of Dnm2 5 0.61 0 11.06
6 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
7 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
8 INT132278 Binding of CTLA4 32 0.39 18.69 8.17
9 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
10 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
11 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
12 INT106599 Positive_regulation of Dnm2 8 0.69 0.28 7.01
13 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
14 INT106596 Transcription of Dnm2 4 0.69 0 4.5
15 INT64711 Regulation of Ngfr 10 0.45 3.12 4.33
16 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94
17 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89
18 INT112928 Localization of Dnm2 3 0.74 0 3.81
19 INT55907 Binding of Ngfr 13 0.47 5.79 3.75
20 INT61540 Negative_regulation of Gene_expression of Ngfr 11 0.59 6.36 3.43
21 INT157401 Gene_expression of Ctla4 21 0.65 15.43 3.2
22 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75
23 INT13943 Localization of DNM2 4 0.52 0.07 2.75
24 INT121463 Regulation of Localization of Dnm2 2 0.45 0 2.72
25 INT75225 Transcription of Ngfr 4 0.60 1.95 2.44
26 INT67796 Negative_regulation of CTLA4 13 0.39 8.36 2.39
27 INT64712 Localization of Ngfr 4 0.78 1.19 1.91
28 INT77415 Localization of GLP1R 23 0.63 11.1 1.69
29 INT111886 Gene_expression of Dnm2 3 0.69 0.91 1.65
30 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63
31 INT140247 Negative_regulation of Negative_regulation of Ngfr 3 0.33 3.15 1.59
32 INT163594 Regulation of Ngfr 5 0.43 2.55 1.53
33 INT242212 Gene_expression of GLP1R 29 0.65 11.36 1.52
34 INT143083 Regulation of CTLA4 4 0.25 1.06 1.36
35 INT64713 Regulation of Gene_expression of Ngfr 4 0.50 2.04 1.36
36 INT138939 Positive_regulation of Transcription of Ngfr 3 0.43 0.89 1.31
37 INT106598 Regulation of Regulation of Dnm2 1 0.44 0 1.31
38 INT264798 Binding of GLP1R 9 0.40 2.95 1.27
39 INT121461 Binding of Dnm2 1 0.24 0 1.23
40 INT164372 Positive_regulation of Positive_regulation of Ngfr 6 0.62 4.1 1.22
41 INT145960 Positive_regulation of GLP1R 19 0.58 7.25 1.19
42 INT110392 Transcription of Ngfr 3 0.52 2.48 1.19
43 INT112929 Negative_regulation of Localization of Dnm2 1 0.29 0 1.13
44 INT163595 Positive_regulation of Regulation of Ngfr 1 0.46 0.57 1.04
45 INT121462 Regulation of Transcription of Dnm2 1 0.20 0 1.03
46 INT111885 Negative_regulation of Transcription of Dnm2 1 0.47 0 0.93
47 INT125580 Positive_regulation of Regulation of Dnm2 1 0.69 0 0.92
48 INT125581 Negative_regulation of Gene_expression of Dnm2 1 0.37 0 0.87
49 INT125582 Regulation of Positive_regulation of Dnm2 1 0.27 0 0.83
50 INT145986 Positive_regulation of CTLA4 8 0.56 2.66 0.82
51 INT94743 Regulation of Ctla4 1 0.44 1.28 0.8
52 INT30397 Positive_regulation of DNM2 3 0.31 1.44 0.79
53 INT13944 Positive_regulation of Localization of DNM2 1 0.12 0 0.79
54 INT34209 Negative_regulation of DNM2 2 0.20 0.29 0.77
55 INT317733 Positive_regulation of Binding of Ngfr 1 0.18 0.51 0.71
56 INT133018 Regulation of Gene_expression of Ngfr 2 0.43 1.47 0.7
57 INT167482 Binding of DNM2 1 0.16 0.42 0.69
58 INT157491 Negative_regulation of Ctla4 5 0.31 2.68 0.63
59 INT228476 Binding of Ctla4 4 0.36 3.03 0.62
60 INT242210 Positive_regulation of Gene_expression of GLP1R 6 0.58 3.59 0.61
61 INT145957 Positive_regulation of Localization of GLP1R 5 0.43 2.12 0.61
62 INT264800 Positive_regulation of Binding of GLP1R 1 0.07 0.17 0.59
63 INT139929 Phosphorylation of Ngfr 3 0.58 1.67 0.57
64 INT118729 Regulation of Transcription of Ngfr 1 0.36 0.45 0.57
65 INT110393 Positive_regulation of Transcription of Ngfr 1 0.46 1 0.54
66 INT300591 Gene_expression of Dnm2 1 0.42 0.26 0.47
67 INT311230 Regulation of GLP1R 6 0.38 3.2 0.45
68 INT264192 Positive_regulation of Gene_expression of CTLA4 6 0.43 2.06 0.45
69 INT160874 Protein_catabolism of CTLA4 1 0.88 0.56 0.39
70 INT165518 Positive_regulation of Regulation of Ngfr 2 0.47 0.47 0.37
71 INT294135 Positive_regulation of Positive_regulation of CTLA4 1 0.25 0.45 0.32
72 INT242207 Negative_regulation of Localization of GLP1R 3 0.36 2.82 0.3
73 INT242211 Negative_regulation of GLP1R 9 0.36 3.4 0.26
74 INT297460 Regulation of Regulation of Ngfr 1 0.33 0.32 0.21
75 INT173956 Negative_regulation of Gene_expression of CTLA4 3 0.37 0.91 0.2
76 INT296068 Regulation of Gene_expression of CTLA4 1 0.16 0.22 0.2
77 INT277827 Localization of CTLA4 1 0.65 0 0.18
78 INT277819 Positive_regulation of Localization of CTLA4 1 0.43 0 0.18
79 INT229557 Positive_regulation of Ctla4 5 0.43 3.83 0.17
80 INT97468 Regulation of DNM2 2 0.26 1.87 0.17
81 INT299419 Transcription of Ctla4 2 0.43 0.71 0.17
82 INT264177 Positive_regulation of Gene_expression of Ctla4 2 0.49 3.59 0.17
83 INT255030 Protein_catabolism of GLP1R 5 0.84 2.39 0.14
84 INT311833 Localization of Ctla4 1 0.17 0.26 0.14
85 INT331971 Positive_regulation of Gene_expression of DNM2 1 0.31 1 0.13
86 INT256404 Positive_regulation of Positive_regulation of GLP1R 2 0.58 1.31 0.1
87 INT297459 Protein_catabolism of Ngfr 1 0.21 0.5 0.1
88 INT311235 Positive_regulation of Protein_catabolism of GLP1R 1 0.42 0.68 0.09
89 INT149118 Regulation of Binding of CTLA4 1 0.33 0.32 0.07
90 INT276341 Transcription of CTLA4 1 0.30 1.04 0.07
91 INT255075 Negative_regulation of Gene_expression of GLP1R 2 0.36 0.64 0.05
92 INT283499 Negative_regulation of Positive_regulation of CTLA4 1 0.09 1.02 0.05
93 INT311238 Negative_regulation of Positive_regulation of GLP1R 1 0.36 0.36 0.05
94 INT229560 Positive_regulation of Positive_regulation of Ctla4 1 0.28 0.53 0.04
95 INT241405 Localization of Ngfr 2 0.56 0.4 0.03
96 INT229558 Negative_regulation of Negative_regulation of Ctla4 1 0.26 0.48 0.03
97 INT283512 Positive_regulation of Binding of CTLA4 1 0.11 1.03 0.03
98 INT241402 Protein_catabolism of Ngfr 1 0.39 0 0.03
99 INT255074 Negative_regulation of Negative_regulation of GLP1R 1 0.27 0.22 0
100 INT193880 Regulation of Phosphorylation of Ngfr 1 0.02 0.25 0
101 INT201629 Negative_regulation of Positive_regulation of Ngfr 1 0.07 0.37 0
102 INT264176 Positive_regulation of Binding of Ctla4 1 0.49 0.22 0
103 INT325815 Positive_regulation of Gene_expression of Dnm2 1 0.45 0.11 0
104 INT297030 Regulation of Gene_expression of DNM2 1 0.32 0.53 0
105 INT209766 Negative_regulation of Gene_expression of DNM2 1 0.27 1.26 0
106 INT174153 Negative_regulation of Gene_expression of Ctla4 1 0.12 0.8 0
107 INT174152 Positive_regulation of Negative_regulation of Ctla4 1 0.14 0.8 0
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