GO:0045340

From wiki-pain
Jump to: navigation, search
Name mercury ion binding
Categary Function
Go Slim No
Go Link GO:0045340
Unique Molecular Interactions 34
Total Molecular Interactions 39
Total Single Events 760
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mercury ion binding. They are ordered first by their pain relevance and then by number of times they were reported for mercury ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5
2 INT116777 Psma5 Positive_regulation of Binding of Fn1 1 0.01 1.24 1.06
3 INT215646 Binding of Adora1 and P2rx2 1 0.13 0.51 0.85
4 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
5 INT158104 Binding of Trpv1 and P2rx2 1 0.03 0.27 0.4
6 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39
7 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39
8 INT15828 Ambp Regulation of Negative_regulation of Fn1 1 0.03 0 0.3
9 INT39567 Txnrd1 Regulation of Localization of Il1f5 1 0.04 0.18 0.21
10 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
11 INT215167 Phosphorylation of Prkaca Positive_regulation of P2rx2 1 0.06 0.13 0.18
12 INT344429 Siglec5 Regulation of Gene_expression of Fn1 1 0.11 0.65 0.18
13 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16
14 INT336665 Binding of P2rx1 and P2rx2 1 0.07 0 0.14
15 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12
16 INT215169 Ptger2 Regulation of P2rx2 1 0.19 0.31 0.11
17 INT10745 Fn1 Regulation of PIF1 1 0.02 0.38 0.1
18 INT38206 Acr Negative_regulation of Txnrd1 1 0.20 0.08 0.08
19 INT336631 Binding of Fn1 and Fgg 1 0.00 0.59 0.04
20 INT336638 Binding of LAMB2 and Fn1 1 0.00 0.58 0.04
21 INT336637 Binding of PTPRC and Fn1 1 0.00 0.32 0
22 INT324058 Fn1 Positive_regulation of Furin 1 0.08 0.27 0
23 INT336636 Binding of Fbln1 and Fn1 1 0.14 0.32 0
24 INT180666 Fn1 Regulation of Transcription of Kras 1 0.31 0 0
25 INT180669 Fn1 Regulation of Kras 1 0.18 0 0
26 INT281097 Binding of P2rx3 and P2rx2 1 0.06 0 0
27 INT246218 Fn1 Positive_regulation of VEGFA 1 0.03 1.13 0
28 INT299157 Binding of Lgals3 and Fn1 1 0.04 0.16 0
29 INT175074 Binding of Fn1 and Psmc1 1 0.02 0.34 0
30 INT351681 Binding of Ecm1 and Fn1 1 0.00 1.14 0
31 INT303439 Egf Positive_regulation of Gene_expression of Fn1 1 0.05 0.82 0
32 INT296725 Binding of P2rx2 and Afm 1 0.10 0 0
33 INT324057 Fn1 Positive_regulation of Gene_expression of Mmp9 1 0.04 1.55 0
34 INT173401 Binding of GPER and Fn1 1 0.00 0.48 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mercury ion binding. They are ordered first by their pain relevance and then by number of times they were reported in mercury ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16
2 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4
3 INT91285 Negative_regulation of P2rx2 29 0.57 12.74 15.48
4 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38
5 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75
6 INT105304 Negative_regulation of Gene_expression of P2rx2 11 0.28 11.07 9.53
7 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47
8 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51
9 INT15725 Positive_regulation of Fn1 17 0.67 14.93 8.03
10 INT120261 Binding of P2rx2 19 0.28 5.8 6.72
11 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02
12 INT105306 Regulation of Gene_expression of P2rx2 7 0.21 6.92 5.22
13 INT148649 Transcription of P2rx2 8 0.43 8.11 4.79
14 INT15724 Negative_regulation of Fn1 15 0.53 5.61 3.87
15 INT215163 Phosphorylation of P2rx2 19 0.60 1.43 3.62
16 INT15827 Regulation of Fn1 8 0.54 4.67 3.47
17 INT81830 Localization of P2rx2 14 0.73 5.42 3.16
18 INT35380 Binding of Fn1 8 0.35 4.84 2.23
19 INT69789 Binding of Fn1 13 0.36 5.08 2.18
20 INT148648 Negative_regulation of Transcription of P2rx2 3 0.29 3.54 1.94
21 INT112648 Positive_regulation of Fn1 19 0.49 13.73 1.66
22 INT160264 Localization of Fn1 10 0.40 3.95 1.51
23 INT168726 Negative_regulation of Positive_regulation of P2rx2 1 0.07 0.09 1.44
24 INT104026 Negative_regulation of Fn1 10 0.22 9.22 1.43
25 INT168727 Negative_regulation of Negative_regulation of P2rx2 1 0.07 0.09 1.43
26 INT142815 Regulation of Regulation of P2rx2 4 0.33 0.69 1.33
27 INT71846 Regulation of Positive_regulation of Fn1 1 0.14 0.13 1.25
28 INT154813 Regulation of Transcription of P2rx2 2 0.26 2.38 1.17
29 INT54043 Transcription of Fn1 3 0.61 1.59 1.1
30 INT215499 Positive_regulation of Phosphorylation of P2rx2 3 0.37 0.57 1.07
31 INT15726 Negative_regulation of Gene_expression of Fn1 8 0.32 5.25 1.04
32 INT146944 Positive_regulation of Positive_regulation of Fn1 1 0.13 1.07 0.85
33 INT39879 Positive_regulation of Gene_expression of Fn1 12 0.41 12.69 0.78
34 INT61292 Positive_regulation of Gene_expression of Fn1 16 0.35 10.25 0.76
35 INT160263 Regulation of Localization of Fn1 3 0.21 0.81 0.76
36 INT251319 Negative_regulation of Gene_expression of Fn1 4 0.07 1.82 0.74
37 INT242989 Regulation of Gene_expression of Fn1 3 0.10 2.42 0.66
38 INT39638 Regulation of Gene_expression of Fn1 3 0.24 0.85 0.64
39 INT17810 Localization of Fn1 4 0.55 2.3 0.62
40 INT215501 Positive_regulation of Binding of P2rx2 3 0.37 0.61 0.56
41 INT107819 Positive_regulation of Localization of P2rx2 1 0.24 0.66 0.55
42 INT251328 Negative_regulation of Localization of Fn1 1 0.10 1.56 0.45
43 INT61293 Transcription of Fn1 3 0.40 2.68 0.36
44 INT38203 Negative_regulation of Txnrd1 4 0.39 0.27 0.35
45 INT217405 Regulation of Positive_regulation of P2rx2 1 0.32 0 0.33
46 INT215492 Negative_regulation of Phosphorylation of P2rx2 1 0.31 0 0.31
47 INT251321 Protein_catabolism of Fn1 3 0.21 1.74 0.3
48 INT247565 Negative_regulation of Negative_regulation of Fn1 3 0.22 4.04 0.25
49 INT160516 Positive_regulation of Transcription of P2rx2 1 0.13 0.2 0.24
50 INT61294 Positive_regulation of Transcription of Fn1 2 0.35 1.01 0.2
51 INT247551 Regulation of Fn1 3 0.25 3.18 0.13
52 INT17809 Positive_regulation of Localization of Fn1 1 0.26 0.52 0.13
53 INT156816 Regulation of Txnrd1 1 0.22 0 0.1
54 INT344634 Negative_regulation of Binding of Fn1 1 0.41 0.49 0.05
55 INT349155 Negative_regulation of Positive_regulation of Fn1 1 0.04 1.13 0
56 INT210663 Positive_regulation of Txnrd1 1 0.05 0.1 0
57 INT251331 Positive_regulation of Localization of Fn1 1 0.08 0.34 0
58 INT57804 Localization of Txnrd1 1 0.61 0.07 0
59 INT210665 Transcription of Txnrd1 1 0.06 0.09 0
60 INT246213 Positive_regulation of Positive_regulation of Fn1 1 0.28 2.18 0
61 INT188052 Positive_regulation of Txnrd1 1 0.23 0.25 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox