GO:0045359

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Name positive regulation of interferon-beta biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045359
Unique Molecular Interactions 663
Total Molecular Interactions 979
Total Single Events 4559
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interferon-beta biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interferon-beta biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
6 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
7 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
8 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
9 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
10 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
11 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
12 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
13 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
14 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
15 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
16 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
17 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
18 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
19 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
20 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
21 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
22 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
23 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
24 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
25 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
26 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
27 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
28 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
29 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
30 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
31 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
32 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
33 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
34 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
35 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
36 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
37 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
38 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
39 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
40 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
41 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
42 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
43 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
44 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
45 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
46 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
47 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
48 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
49 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
50 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
51 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
52 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
53 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
54 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
55 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
56 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
57 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
58 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
59 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
60 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
61 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
62 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
63 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
64 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
65 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
66 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
67 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
68 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
69 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
70 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
71 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
72 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
73 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
74 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
75 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
76 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
77 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
78 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
79 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
80 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
81 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
82 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
83 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
84 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
85 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
86 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
87 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
88 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
89 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
90 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
91 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
92 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
93 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
94 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
95 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
96 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
97 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
98 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
99 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44
100 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
101 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
102 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
103 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
104 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
105 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
106 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4
107 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
108 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
109 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
110 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
111 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
112 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
113 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
114 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
115 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
116 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
117 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
118 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
119 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
120 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
121 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
122 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
123 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
124 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
125 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
126 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
127 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
128 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
129 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37
130 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
131 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
132 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
133 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
134 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
135 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
136 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
137 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
138 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
139 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
140 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
141 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
142 INT110134 Tlr4 Regulation of Regulation of Gnrh1 1 0.01 0.15 0.33
143 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
144 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
145 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32
146 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
147 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32
148 INT295198 Tlr4 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.15 0.32
149 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
150 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
151 INT137160 TLR7 Positive_regulation of Gene_expression of CXCR3 1 0.35 0.34 0.32
152 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32
153 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31
154 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31
155 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
156 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31
157 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31
158 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
159 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
160 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
161 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31
162 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
163 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
164 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
165 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
166 INT223752 Tlr4 Positive_regulation of Il1 1 0.12 0.64 0.3
167 INT178342 Positive_regulation of Tlr4 Positive_regulation of Il6 1 0.13 0.25 0.3
168 INT306319 Cd14 Positive_regulation of Tlr4 1 0.48 0.29 0.3
169 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
170 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29
171 INT137163 Binding of TLR5 and TLR9 1 0.25 0.33 0.29
172 INT137169 Binding of TLR5 and TLR7 1 0.25 0.33 0.29
173 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
174 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28
175 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28
176 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
177 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
178 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
179 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27
180 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
181 INT295197 Tlr4 Positive_regulation of Ptger2 1 0.01 0.05 0.27
182 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
183 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27
184 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27
185 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27
186 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27
187 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27
188 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
189 INT78067 Tlr4 Positive_regulation of Localization of Ptger2 1 0.01 0.07 0.26
190 INT290707 Binding of Tlr4 and Cd200r1 1 0.01 0.7 0.26
191 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26
192 INT310766 Tlr4 Positive_regulation of Cxcl2 1 0.29 0.28 0.26
193 INT306325 Tlr4 Positive_regulation of Localization of Cd14 1 0.39 0.37 0.26
194 INT295200 Hspg2 Positive_regulation of Tlr4 1 0.00 0 0.25
195 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
196 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
197 INT350074 Binding of Tlr4 and Myadm 1 0.00 0.5 0.25
198 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25
199 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25
200 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interferon-beta biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interferon-beta biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
3 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
4 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
5 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
6 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
7 INT134651 Binding of TLR4 89 0.48 66.96 23.19
8 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
9 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
10 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
11 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
12 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
13 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
14 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
15 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
16 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
17 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
18 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
19 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
20 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
21 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
22 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
23 INT97797 Localization of TLR4 18 0.77 13.78 6
24 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
25 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
26 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
27 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43
28 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41
29 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
30 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
31 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
32 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
33 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
34 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
35 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
36 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
37 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
38 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
39 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
40 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
41 INT92335 Gene_expression of TBK1 11 0.28 8.98 3
42 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
43 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
44 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
45 INT204524 Binding of TLR9 17 0.43 11.69 2.76
46 INT97132 Negative_regulation of Positive_regulation of TBK1 5 0.08 6.54 2.76
47 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
48 INT183468 Localization of TBK1 6 0.32 4.35 2.36
49 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21
50 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
51 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
52 INT134919 Binding of Ticam1 6 0.18 1.12 1.94
53 INT188678 Binding of Tlr7 14 0.32 6.6 1.89
54 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
55 INT178188 Positive_regulation of Tlr7 12 0.40 6.33 1.77
56 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
57 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
58 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
59 INT174689 Gene_expression of Tlr7 11 0.67 8.24 1.56
60 INT204530 Positive_regulation of Gene_expression of TLR9 14 0.70 6.85 1.48
61 INT258048 Regulation of TBK1 4 0.05 3.81 1.44
62 INT186810 Positive_regulation of TLR3 13 0.65 6.37 1.37
63 INT150730 Regulation of Tlr3 2 0.45 6.51 1.37
64 INT219159 Positive_regulation of TLR7 8 0.55 2.37 1.32
65 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
66 INT151567 Gene_expression of Tlr9 6 0.72 3.63 1.26
67 INT183790 Binding of TBK1 2 0.04 2.97 1.16
68 INT150729 Negative_regulation of Tlr3 3 0.43 3.26 1.14
69 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
70 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08
71 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05
72 INT118738 Transcription of Tlr4 4 0.70 1.39 1
73 INT134917 Localization of Ticam1 2 0.51 0.6 0.99
74 INT288483 Gene_expression of Tlr3 8 0.72 4.51 0.97
75 INT120599 Binding of Tlr7 2 0.27 2.16 0.96
76 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
77 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
78 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
79 INT134912 Positive_regulation of Localization of Ticam1 1 0.24 0.32 0.87
80 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
81 INT263481 Regulation of Positive_regulation of TBK1 1 0.07 1.28 0.81
82 INT186804 Binding of TLR3 14 0.45 8.41 0.79
83 INT352771 Positive_regulation of Localization of TBK1 1 0.05 0.98 0.78
84 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
85 INT280014 Binding of TLR7 4 0.14 3.52 0.76
86 INT288495 Gene_expression of Tlr7 3 0.50 2.83 0.76
87 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
88 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
89 INT294787 Localization of TLR9 2 0.67 2.35 0.75
90 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
91 INT331594 Localization of Tlr9 1 0.41 1.66 0.71
92 INT331595 Positive_regulation of Localization of Tlr9 1 0.28 1.66 0.71
93 INT255974 Transcription of Tlr3 10 0.49 6.11 0.7
94 INT186798 Regulation of TLR3 5 0.42 3.13 0.69
95 INT314571 Binding of Tbk1 3 0.24 2.88 0.69
96 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
97 INT322032 Binding of TLR8 3 0.32 2.57 0.69
98 INT333595 Negative_regulation of Gene_expression of TBK1 2 0.12 0.91 0.67
99 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
100 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
101 INT296782 Phosphorylation of Tlr9 1 0.61 0.53 0.63
102 INT204525 Negative_regulation of Gene_expression of TLR3 2 0.54 1.8 0.61
103 INT288485 Regulation of Transcription of Tlr3 1 0.20 0.85 0.61
104 INT246423 Negative_regulation of TLR3 1 0.40 2.2 0.6
105 INT178202 Regulation of Tlr7 2 0.34 1.69 0.59
106 INT254177 Positive_regulation of Positive_regulation of Tlr3 3 0.41 2.06 0.58
107 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
108 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
109 INT183685 Positive_regulation of Gene_expression of Tlr3 4 0.61 1.5 0.53
110 INT260425 Positive_regulation of Gene_expression of Tlr7 3 0.39 2.88 0.53
111 INT190864 Positive_regulation of Phosphorylation of Tbk1 1 0.08 0.68 0.53
112 INT190859 Phosphorylation of Tbk1 1 0.12 0.68 0.52
113 INT288490 Binding of Tlr9 1 0.25 1.88 0.51
114 INT285448 Positive_regulation of Gene_expression of TLR7 4 0.61 2.58 0.5
115 INT245223 Negative_regulation of Gene_expression of TLR7 3 0.37 2.81 0.5
116 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
117 INT188677 Positive_regulation of Positive_regulation of Tlr9 2 0.29 1.22 0.49
118 INT200677 Transcription of TBK1 2 0.14 0.74 0.49
119 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
120 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
121 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
122 INT263479 Positive_regulation of Transcription of TBK1 1 0.12 0.32 0.46
123 INT183470 Positive_regulation of Negative_regulation of TBK1 1 0.08 0.46 0.46
124 INT260427 Negative_regulation of Tlr7 2 0.33 1.42 0.42
125 INT237905 Positive_regulation of Binding of Tlr3 1 0.30 0.79 0.42
126 INT178171 Localization of Tlr7 1 0.51 0.53 0.41
127 INT204533 Regulation of Gene_expression of TLR9 8 0.55 2.81 0.4
128 INT183680 Localization of Tlr3 6 0.71 1.69 0.39
129 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
130 INT219171 Negative_regulation of Positive_regulation of TLR9 1 0.18 1.3 0.39
131 INT219182 Negative_regulation of Positive_regulation of TLR7 1 0.24 1.3 0.39
132 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
133 INT250167 Negative_regulation of Ticam1 3 0.29 2.03 0.37
134 INT182134 Transcription of TLR9 2 0.72 1.21 0.37
135 INT284455 Regulation of Gene_expression of Tlr9 1 0.30 1.19 0.37
136 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
137 INT246419 Positive_regulation of Negative_regulation of TLR3 1 0.43 0.67 0.34
138 INT207897 Positive_regulation of TLR8 3 0.17 2.52 0.33
139 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
140 INT329061 Positive_regulation of Tlr9 1 0.47 2.05 0.29
141 INT314573 Positive_regulation of Binding of Tbk1 1 0.30 0.14 0.29
142 INT331590 Negative_regulation of Binding of Tlr9 1 0.24 1.52 0.28
143 INT204528 Negative_regulation of Gene_expression of TLR9 5 0.52 4.47 0.27
144 INT236357 Negative_regulation of Positive_regulation of Tlr9 2 0.33 3.1 0.27
145 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
146 INT207896 Gene_expression of TLR8 3 0.36 2.82 0.26
147 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
148 INT219175 Localization of TLR7 2 0.49 1.32 0.25
149 INT204531 Negative_regulation of TLR9 1 0.43 1.29 0.25
150 INT254195 Gene_expression of Ticam1 3 0.29 0.46 0.24
151 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
152 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
153 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
154 INT186803 Transcription of TLR3 6 0.67 1.54 0.2
155 INT347982 Negative_regulation of Tbk1 1 0.28 1.41 0.2
156 INT347991 Gene_expression of Tbk1 1 0.43 1.42 0.2
157 INT245222 Regulation of TLR7 2 0.39 1.52 0.19
158 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19
159 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19
160 INT324768 Positive_regulation of Ticam1 2 0.16 0.14 0.18
161 INT334246 Positive_regulation of Protein_catabolism of Tlr4 1 0.07 0.18 0.18
162 INT306008 Positive_regulation of Transcription of Tlr4 2 0.50 1.41 0.16
163 INT336418 Negative_regulation of Binding of Tlr3 1 0.36 0.59 0.16
164 INT324781 Protein_catabolism of Ticam1 1 0.27 0.74 0.15
165 INT254190 Positive_regulation of Binding of Ticam1 1 0.22 0.32 0.15
166 INT350779 Positive_regulation of Positive_regulation of TLR9 1 0.08 0.8 0.15
167 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
168 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
169 INT204527 Regulation of TLR9 7 0.40 2.88 0.12
170 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
171 INT186797 Localization of TLR3 2 0.70 2.69 0.12
172 INT120600 Positive_regulation of Binding of Tlr7 1 0.04 0.17 0.12
173 INT260428 Regulation of Gene_expression of Tlr7 1 0.25 1.01 0.12
174 INT151569 Transcription of Tlr9 3 0.69 0.75 0.11
175 INT186809 Positive_regulation of Transcription of TLR3 2 0.65 0.5 0.11
176 INT151566 Positive_regulation of Transcription of Tlr9 2 0.47 0.67 0.11
177 INT246420 Regulation of Gene_expression of TLR3 1 0.57 0.79 0.11
178 INT188681 Positive_regulation of Binding of Tlr7 1 0.17 0 0.11
179 INT255970 Regulation of Transcription of Tlr3 1 0.24 0.89 0.09
180 INT254181 Positive_regulation of Tbk1 1 0.06 0.24 0.09
181 INT280012 Positive_regulation of Binding of TLR7 1 0.18 1.11 0.09
182 INT280015 Positive_regulation of Binding of TLR9 1 0.12 1.11 0.09
183 INT329066 Positive_regulation of Gene_expression of Tlr3 1 0.43 1.12 0.08
184 INT322026 Positive_regulation of Positive_regulation of TLR7 1 0.40 0.06 0.08
185 INT222842 Localization of Tbk1 1 0.25 0.22 0.08
186 INT228376 Binding of Tlr3 2 0.45 2.2 0.07
187 INT285436 Negative_regulation of Transcription of TLR3 1 0.24 0.32 0.07
188 INT254184 Positive_regulation of Gene_expression of Ticam1 1 0.22 0.11 0.06
189 INT276930 Regulation of Regulation of Tlr4 1 0.17 0.45 0.05
190 INT334959 Regulation of Gene_expression of TLR8 1 0.21 0.91 0.05
191 INT242899 Negative_regulation of Negative_regulation of TLR4 1 0.20 0.09 0.05
192 INT184726 Negative_regulation of Protein_catabolism of Tlr4 2 0.36 0.21 0.04
193 INT213682 Positive_regulation of Gene_expression of TBK1 2 0.21 2.18 0.04
194 INT333622 Phosphorylation of TBK1 1 0.17 0.35 0.04
195 INT288492 Negative_regulation of Gene_expression of Tlr7 1 0.32 0.63 0.04
196 INT200681 Regulation of Transcription of TBK1 1 0.03 0.42 0.04
197 INT231780 Regulation of Transcription of TLR4 1 0.19 0.62 0.04
198 INT329051 Positive_regulation of Tlr3 1 0.65 0.33 0.04
199 INT320335 Positive_regulation of Transcription of Tlr3 1 0.43 0.13 0.03
200 INT350784 Positive_regulation of TICAM1 1 0.05 0 0.03
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