GO:0045404

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Name positive regulation of interleukin-4 biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045404
Unique Molecular Interactions 23
Total Molecular Interactions 50
Total Single Events 416
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-4 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-4 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
2 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
3 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
4 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
5 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48
6 INT300549 Il1 Regulation of Gene_expression of Irf4 1 0.01 0.63 0.33
7 INT337168 DCPS Negative_regulation of CD86 1 0.02 1.54 0.21
8 INT334261 Binding of Irf4 and Irf5 1 0.22 0.42 0.18
9 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16
10 INT182480 Binding of Cd1d1 and Cxcr6 1 0.27 0.25 0.15
11 INT312707 Positive_regulation of DPP4 Positive_regulation of Gene_expression of CD86 1 0.20 0.45 0.13
12 INT236317 IGKV2D-38 Positive_regulation of CD86 1 0.02 0.13 0.1
13 INT352358 CD86 Positive_regulation of GOPC 1 0.30 0.13 0.07
14 INT337179 Binding of TLR3 and Positive_regulation of CD86 1 0.10 0.31 0.03
15 INT287072 Chrm2 Positive_regulation of Gene_expression of Irf4 1 0.18 0.06 0
16 INT287060 Proc Regulation of Irf4 1 0.00 0.13 0
17 INT287076 Chrm2 Regulation of Irf4 1 0.10 0.09 0
18 INT236319 IGKV2D-38 Regulation of CD86 1 0.03 0.5 0
19 INT287068 Irf4 Regulation of Igj 1 0.25 0.13 0
20 INT352079 Binding of CD86 and ADAM11 1 0.10 0.77 0
21 INT298105 Ca2 Negative_regulation of Cd1d1 1 0.12 0.09 0
22 INT287066 Chrm2 Positive_regulation of Irf4 1 0.18 0.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-4 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-4 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36
2 INT19620 Binding of CD86 30 0.47 12.01 9.89
3 INT174117 Gene_expression of Cd1d1 26 0.75 12.07 3.07
4 INT155486 Positive_regulation of Gene_expression of CD86 16 0.69 14.6 2.86
5 INT75685 Regulation of CD86 12 0.58 3.55 2.66
6 INT19621 Positive_regulation of CD86 23 0.69 14 2.58
7 INT19617 Negative_regulation of CD86 12 0.42 3.68 1.77
8 INT137807 Binding of Cd1d1 4 0.31 1.26 0.94
9 INT209958 Negative_regulation of Binding of CD86 1 0.40 0.28 0.85
10 INT155485 Regulation of Gene_expression of CD86 7 0.61 3.73 0.6
11 INT182468 Positive_regulation of Cd1d1 5 0.61 4.08 0.48
12 INT200258 Binding of Irf4 2 0.21 0.43 0.43
13 INT174118 Regulation of Gene_expression of Cd1d1 1 0.44 1.42 0.4
14 INT276311 Gene_expression of Irf4 6 0.64 4.95 0.37
15 INT287043 Positive_regulation of Irf4 7 0.57 2.81 0.36
16 INT236332 Negative_regulation of Gene_expression of CD86 9 0.42 4.4 0.35
17 INT222639 Gene_expression of Cd1d1 2 0.65 0.65 0.32
18 INT182465 Negative_regulation of Cd1d1 4 0.28 1.72 0.29
19 INT174116 Negative_regulation of Gene_expression of Cd1d1 1 0.31 0.51 0.24
20 INT182453 Positive_regulation of Gene_expression of Cd1d1 6 0.67 1.64 0.21
21 INT181847 Negative_regulation of Positive_regulation of CD86 1 0.41 0.98 0.1
22 INT298112 Negative_regulation of Cd1d1 1 0.42 0.09 0.09
23 INT352366 Localization of CD86 1 0.74 0.29 0.07
24 INT352365 Positive_regulation of Localization of CD86 1 0.50 0.29 0.07
25 INT218004 Regulation of Cd1d1 3 0.44 0.37 0.06
26 INT352367 Positive_regulation of Regulation of CD86 1 0.50 0.06 0.06
27 INT182470 Negative_regulation of Positive_regulation of Cd1d1 1 0.28 0.1 0.06
28 INT264199 Positive_regulation of Binding of CD86 2 0.25 0.82 0.03
29 INT337245 Positive_regulation of Positive_regulation of CD86 1 0.22 0.62 0.03
30 INT19618 Regulation of Binding of CD86 1 0.00 0.09 0
31 INT337202 Transcription of CD86 1 0.30 0.62 0
32 INT182467 Localization of Cd1d1 1 0.48 0.25 0
33 INT298114 Localization of Cd1d1 1 0.73 0 0
34 INT218005 Phosphorylation of Cd1d1 1 0.05 0.17 0
35 INT218002 Positive_regulation of Cd1d1 1 0.03 0.27 0
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