GO:0045416

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Name positive regulation of interleukin-8 biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045416
Unique Molecular Interactions 1566
Total Molecular Interactions 2226
Total Single Events 17763
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-8 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of interleukin-8 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
5 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
6 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
7 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
8 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
9 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
10 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
11 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
12 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
13 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
14 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
15 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
16 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
17 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
18 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
19 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
20 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
21 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
22 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
23 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
24 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
25 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
26 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
27 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
28 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
29 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
30 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
31 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
32 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
33 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
34 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
35 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
36 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
37 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
38 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
39 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
40 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
41 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
42 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
43 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
44 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
45 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
46 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
47 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
48 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
49 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
50 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
51 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
52 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
53 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
54 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
55 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
56 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
57 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
58 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
59 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
60 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
61 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
62 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
63 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
64 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
65 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
66 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
67 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
68 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
69 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
70 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
71 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
72 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
73 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
74 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
75 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
76 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
77 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
78 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
79 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
80 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
81 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
82 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
83 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
84 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
85 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
86 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
87 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
88 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
89 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
90 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
91 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
92 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
93 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
94 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
95 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
96 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
97 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
98 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
99 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
100 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
101 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
102 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
103 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
104 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98
105 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
106 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
107 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
108 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
109 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
110 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
111 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
112 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
113 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
114 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
115 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
116 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
117 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
118 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
119 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
120 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
121 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
122 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
123 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
124 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
125 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
126 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
127 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
128 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
129 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
130 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
131 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
132 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
133 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
134 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
135 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
136 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
137 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
138 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
139 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
140 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
141 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
142 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
143 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
144 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
145 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
146 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
147 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
148 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
149 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
150 INT32441 POMC Positive_regulation of ELANE 1 0.13 0.09 0.83
151 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
152 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
153 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
154 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
155 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
156 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
157 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
158 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
159 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
160 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
161 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
162 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
163 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
164 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
165 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
166 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
167 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
168 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
169 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
170 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
171 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
172 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
173 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
174 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
175 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
176 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
177 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
178 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
179 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
180 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
181 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
182 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
183 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
184 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
185 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
186 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
187 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
188 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
189 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
190 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
191 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
192 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
193 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
194 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
195 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
196 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
197 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
198 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
199 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7
200 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of interleukin-8 biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of interleukin-8 biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99
11 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
12 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
13 INT10166 Localization of Tnf 237 0.81 153.95 88.64
14 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
15 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
16 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
17 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
18 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
19 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
20 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
21 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
22 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
23 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
24 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
25 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
26 INT13354 Transcription of TNF 108 0.72 85.81 42.32
27 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
28 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
29 INT35406 Localization of Tnf 94 0.81 64.63 31.65
30 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
31 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
32 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94
33 INT2609 Localization of ELANE 111 0.81 50.22 26.63
34 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
35 INT134651 Binding of TLR4 89 0.48 66.96 23.19
36 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
37 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09
38 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
39 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79
40 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
41 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
42 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
43 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
44 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
45 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
46 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
47 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
48 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
49 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
50 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
51 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
52 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
53 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
54 INT10173 Binding of Tnf 45 0.48 35.6 14.32
55 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
56 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
57 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
58 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
59 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
60 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
61 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
62 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
63 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
64 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
65 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
66 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
67 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
68 INT68299 Binding of Tnf 17 0.39 12.55 7.49
69 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
70 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
71 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
72 INT2605 Regulation of ELANE 39 0.61 18.22 7.11
73 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
74 INT19146 Negative_regulation of Apoa2 19 0.36 5.34 6.73
75 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
76 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
77 INT97797 Localization of TLR4 18 0.77 13.78 6
78 INT116420 Localization of Elane 16 0.14 7.8 6
79 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
80 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
81 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
82 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
83 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
84 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
85 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
86 INT10100 Binding of ELANE 22 0.47 15.32 5.19
87 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
88 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
89 INT17582 Negative_regulation of Localization of ELANE 17 0.53 6.11 4.89
90 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
91 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08
92 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
93 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
94 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
95 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
96 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
97 INT179656 Gene_expression of Elane 12 0.32 9.44 3.53
98 INT22891 Positive_regulation of Localization of ELANE 16 0.69 11.52 3.42
99 INT42581 Regulation of Gene_expression of ELANE 11 0.38 9.25 3.38
100 INT22823 Positive_regulation of Positive_regulation of ELANE 12 0.45 6.89 3.35
101 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
102 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
103 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12
104 INT28731 Negative_regulation of Elane 14 0.14 8.97 3.01
105 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
106 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
107 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
108 INT10556 Regulation of Apoa2 5 0.44 0.51 2.8
109 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
110 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
111 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
112 INT2452 Localization of Apoa2 9 0.55 0 2.3
113 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
114 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21
115 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
116 INT124583 Negative_regulation of Elane 8 0.29 5.26 2.14
117 INT42583 Protein_catabolism of ELANE 8 0.89 4.33 2.11
118 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
119 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
120 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
121 INT51502 Positive_regulation of Elane 5 0.22 2.3 1.94
122 INT188678 Binding of Tlr7 14 0.32 6.6 1.89
123 INT36245 Negative_regulation of Gene_expression of ELANE 11 0.40 5.32 1.88
124 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
125 INT83358 Positive_regulation of Elane 8 0.21 8.14 1.83
126 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81
127 INT178188 Positive_regulation of Tlr7 12 0.40 6.33 1.77
128 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
129 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
130 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
131 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
132 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
133 INT174689 Gene_expression of Tlr7 11 0.67 8.24 1.56
134 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
135 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
136 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
137 INT219159 Positive_regulation of TLR7 8 0.55 2.37 1.32
138 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
139 INT5652 Negative_regulation of Positive_regulation of ELANE 7 0.37 2.46 1.21
140 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
141 INT17805 Regulation of Localization of ELANE 7 0.59 1.88 1.08
142 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
143 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
144 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
145 INT118738 Transcription of Tlr4 4 0.70 1.39 1
146 INT120599 Binding of Tlr7 2 0.27 2.16 0.96
147 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89
148 INT32443 Negative_regulation of Binding of ELANE 2 0.11 0.54 0.89
149 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
150 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
151 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
152 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
153 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
154 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
155 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
156 INT203132 Negative_regulation of Gene_expression of Elane 1 0.20 1.5 0.86
157 INT116419 Negative_regulation of Localization of Elane 2 0.01 0.58 0.82
158 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
159 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
160 INT142422 Regulation of Positive_regulation of ELANE 1 0.02 0.65 0.78
161 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
162 INT280014 Binding of TLR7 4 0.14 3.52 0.76
163 INT46295 Regulation of Negative_regulation of ELANE 4 0.39 2.34 0.76
164 INT288495 Gene_expression of Tlr7 3 0.50 2.83 0.76
165 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
166 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
167 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
168 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
169 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
170 INT322032 Binding of TLR8 3 0.32 2.57 0.69
171 INT153008 Gene_expression of Elane 3 0.66 1.66 0.67
172 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
173 INT25374 Negative_regulation of Negative_regulation of Apoa2 1 0.30 0.24 0.67
174 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
175 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63
176 INT235079 Negative_regulation of Phosphorylation of TNF 2 0.41 1.16 0.6
177 INT178202 Regulation of Tlr7 2 0.34 1.69 0.59
178 INT51501 Positive_regulation of Positive_regulation of Elane 1 0.09 0.5 0.59
179 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
180 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
181 INT260425 Positive_regulation of Gene_expression of Tlr7 3 0.39 2.88 0.53
182 INT10983 Binding of Apoa2 7 0.45 4.21 0.52
183 INT179665 Protein_catabolism of Elane 3 0.15 3.19 0.52
184 INT285448 Positive_regulation of Gene_expression of TLR7 4 0.61 2.58 0.5
185 INT245223 Negative_regulation of Gene_expression of TLR7 3 0.37 2.81 0.5
186 INT179666 Positive_regulation of Gene_expression of Elane 3 0.21 1.84 0.5
187 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
188 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
189 INT153430 Binding of Elane 2 0.47 1.92 0.48
190 INT43397 Positive_regulation of Localization of Apoa2 1 0.09 0 0.48
191 INT141194 Regulation of Negative_regulation of Tnf 3 0.42 1.57 0.47
192 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
193 INT235200 Positive_regulation of Negative_regulation of ELANE 3 0.38 1.68 0.46
194 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
195 INT138003 Positive_regulation of Negative_regulation of Tnf 2 0.49 2.07 0.43
196 INT260427 Negative_regulation of Tlr7 2 0.33 1.42 0.42
197 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41
198 INT178171 Localization of Tlr7 1 0.51 0.53 0.41
199 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
200 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
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