GO:0045444

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Name fat cell differentiation
Categary Process
Go Slim No
Go Link GO:0045444
Unique Molecular Interactions 463
Total Molecular Interactions 590
Total Single Events 5606
Pain Genes Associated 52

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
2 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
3 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
4 INT128292 Nts Positive_regulation of Insr 1 0.03 0.99 3.34
5 INT128291 Vom1r68 Positive_regulation of Insr 1 0.00 0.99 3.33
6 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
7 INT147652 PLCB1 Negative_regulation of Positive_regulation of TRPV1 1 0.27 0.92 1.62
8 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
9 INT150682 Pomc Regulation of Gene_expression of Eif2ak3 1 0.37 0.17 1.44
10 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
11 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
12 INT128700 BBS9 Negative_regulation of Il12a 1 0.47 0.76 1.03
13 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
14 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
15 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
16 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
17 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
18 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
19 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
20 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
21 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
22 INT150680 Pomc Negative_regulation of Gene_expression of Eif2ak3 1 0.35 0.07 0.8
23 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
24 INT76499 Binding of Insr and Adora2a 1 0.08 0 0.76
25 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
26 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
27 INT163946 Binding of ERAP1 and Il23r 1 0.23 0.56 0.72
28 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
29 INT160711 Binding of KIR3DL1 and ERAP1 1 0.15 0.71 0.71
30 INT8980 Gal Regulation of PLCB1 1 0.18 0.13 0.68
31 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
32 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
33 INT46493 Binding of Insr and Oxt 1 0.14 0 0.62
34 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
35 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6
36 INT89010 Arc Positive_regulation of Insr 1 0.08 0.86 0.59
37 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
38 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58
39 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
40 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
41 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
42 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49
43 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
44 INT172137 IL11 Negative_regulation of Gene_expression of TNF 1 0.09 0.73 0.47
45 INT233668 Cebpd Negative_regulation of Cebpg 1 0.43 0.66 0.46
46 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
47 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46
48 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
49 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46
50 INT161654 Gsr Regulation of Gpx1 1 0.14 0.85 0.42
51 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
52 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
53 INT264135 Socs1 Positive_regulation of Protein_catabolism of TOLLIP 1 0.00 0.33 0.41
54 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4
55 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39
56 INT28237 BBS2 Positive_regulation of Localization of Cck 1 0.04 0.33 0.39
57 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
58 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
59 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38
60 INT151546 Adcy1 Positive_regulation of Atf2 1 0.36 0.37 0.37
61 INT151549 Regulation of Adcy1 Positive_regulation of Atf2 1 0.33 0.37 0.37
62 INT123511 TIAF1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0.6 0.37
63 INT151551 Regulation of Camk4 Positive_regulation of Atf2 1 0.34 0.36 0.37
64 INT151547 Camk4 Positive_regulation of Atf2 1 0.38 0.36 0.37
65 INT123495 Negative_regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
66 INT123493 Regulation of Binding of Egr1 and Ccr5 1 0.03 0.48 0.36
67 INT336573 Ptpn2 Regulation of INSR 1 0.00 1.36 0.36
68 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36
69 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
70 INT66369 Pomc Regulation of Positive_regulation of Gsk3b 1 0.07 0 0.35
71 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
72 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33
73 INT321366 Gsk3b Regulation of Gene_expression of CYP8B1 1 0.01 0.21 0.33
74 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
75 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32
76 INT110464 Cpe Regulation of Phosphorylation of Atf2 1 0.02 0 0.32
77 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32
78 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
79 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32
80 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
81 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
82 INT110459 Binding of Atf2 and Jun 1 0.32 0 0.31
83 INT315394 IFNA1 Positive_regulation of Gene_expression of Socs1 1 0.01 0.41 0.31
84 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
85 INT315398 IFNA1 Positive_regulation of Socs1 1 0.01 0.41 0.3
86 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29
87 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
88 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28
89 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
90 INT290957 Lsd Positive_regulation of Gene_expression of Egr2 1 0.11 0.1 0.26
91 INT248318 RETN Regulation of VEGFA 1 0.00 0.43 0.26
92 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26
93 INT85791 Prlh Regulation of Localization of Prl 1 0.23 0 0.26
94 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
95 INT41406 Binding of Insr and Thtpa 1 0.05 0 0.25
96 INT157957 Ppyr1 Negative_regulation of Phosphorylation of PLCB1 1 0.00 0.24 0.24
97 INT169048 Positive_regulation of Binding of Atf2 and Sult4a1 1 0.38 0.11 0.24
98 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
99 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
100 INT85792 Prlh Positive_regulation of Localization of Prl 1 0.39 0 0.24
101 INT169054 Binding of Atf2 and Sult4a1 1 0.37 0.11 0.24
102 INT294290 PROK1 Positive_regulation of Gene_expression of IL11 1 0.59 0.46 0.23
103 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
104 INT89158 Grpr Positive_regulation of Localization of Insr 1 0.02 0 0.23
105 INT255942 Elk1 Regulation of Binding of ATF2 1 0.07 0.12 0.22
106 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22
107 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22
108 INT255941 ATF2 Regulation of Transcription of Elk1 1 0.07 0.12 0.22
109 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22
110 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22
111 INT255937 ATF2 Regulation of Binding of Elk1 1 0.07 0.12 0.22
112 INT255939 Elk1 Regulation of Transcription of ATF2 1 0.07 0.12 0.22
113 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21
114 INT85760 Binding of Pnoc and Noc3l 1 0.01 0 0.21
115 INT339510 Tlr4 Positive_regulation of Socs1 1 0.06 0.1 0.18
116 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18
117 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18
118 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18
119 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18
120 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
121 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
122 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17
123 INT81297 Positive_regulation of Pparg Regulation of Gene_expression of Nos2 1 0.23 0.17 0.17
124 INT294292 PROK1 Regulation of IL11 1 0.53 0.42 0.17
125 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17
126 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17
127 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
128 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
129 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
130 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
131 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
132 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
133 INT339513 Binding of Socs1 and Eif2ak2 1 0.04 0.07 0.15
134 INT294309 PROK1 Regulation of Gene_expression of IL11 1 0.53 0.25 0.15
135 INT106506 Binding of Pparg and Ptgds 1 0.42 0.31 0.14
136 INT338449 Nps Regulation of Alms1 1 0.04 0.13 0.14
137 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14
138 INT184122 Binding of Socs1 and Sh2 1 0.14 0 0.14
139 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 0.01 0.41 0.13
140 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
141 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
142 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
143 INT308534 Binding of HIVEP1 and Alms1 1 0.00 0.96 0.13
144 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13
145 INT263320 Gsk3b Regulation of Uts2r 1 0.02 0.68 0.13
146 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
147 INT263318 Akt1 Regulation of Gsk3b 1 0.02 0.75 0.13
148 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13
149 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
150 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13
151 INT354327 Gsk3b Positive_regulation of Gene_expression of Ide 1 0.17 0.33 0.13
152 INT59807 ADRA1D Positive_regulation of PLCB1 1 0.33 0 0.13
153 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12
154 INT101173 Pparg Regulation of Positive_regulation of Nfkb1 1 0.03 0.07 0.12
155 INT101174 Pparg Regulation of Gene_expression of IK 1 0.00 0.07 0.12
156 INT143662 Rere Regulation of Gpx1 1 0.69 0.56 0.12
157 INT100478 Binding of Camk1d and Alms1 1 0.17 0 0.12
158 INT185162 Binding of CRP and Retn 1 0.13 2.8 0.12
159 INT128551 Binding of Cebpb and Nr3c1 1 0.06 0.15 0.11
160 INT184522 Positive_regulation of Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.95 0.11
161 INT187468 Alms1 Positive_regulation of H2-D1 1 0.02 0.32 0.11
162 INT268634 Ptpn2 Positive_regulation of Positive_regulation of Gsk3b 1 0.02 1.08 0.11
163 INT184521 Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.94 0.11
164 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11
165 INT184520 Ptger2 Regulation of Ccnd1 1 0.00 0.94 0.11
166 INT268626 Mpz Positive_regulation of Positive_regulation of Gsk3b 1 0.29 1.08 0.11
167 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11
168 INT293411 IL8 Regulation of IL11 1 0.03 1.17 0.1
169 INT245185 Binding of RRAD and TCF7L2 1 0.00 6.88 0.1
170 INT293417 HRAS Regulation of IL11 1 0.00 1.17 0.1
171 INT32546 Gsk3b Negative_regulation of Localization of Gnrh1 1 0.05 0 0.1
172 INT32547 Gsk3b Negative_regulation of Localization of LH 1 0.04 0 0.1
173 INT137368 Retn Positive_regulation of Gene_expression of IGF1 1 0.00 0.17 0.1
174 INT245182 Binding of SPINK1 and TCF7L2 1 0.39 2.05 0.1
175 INT312839 Egr2 Regulation of Gene_expression of Mbp 1 0.32 0.16 0.09
176 INT312843 Egr2 Regulation of Gene_expression of Plp1 1 0.31 0.16 0.09
177 INT339500 Negative_regulation of Socs1 Positive_regulation of Eif2ak2 1 0.05 0.31 0.09
178 INT312840 Egr2 Regulation of Gene_expression of Mag 1 0.31 0.16 0.09
179 INT349660 Binding of INSR and PYCARD 1 0.01 0 0.09
180 INT54095 ERAP1 Regulation of Protein_catabolism of Fgg 1 0.00 0 0.09
181 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
182 INT294295 PROK1 Positive_regulation of IL11 1 0.40 0.15 0.09
183 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09
184 INT335772 MIR155 Regulation of SOCS1 1 0.01 0.29 0.09
185 INT294289 IL11 Positive_regulation of Gene_expression of NPEPPS 1 0.01 0.06 0.09
186 INT215884 Eif2ak3 Positive_regulation of Gene_expression of Musd1 1 0.01 0.96 0.09
187 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
188 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
189 INT214752 EDNRA Positive_regulation of PLCB1 1 0.02 0 0.08
190 INT325059 Insr Positive_regulation of Ang 1 0.02 1.4 0.08
191 INT115258 Insr Positive_regulation of Phosphorylation of Irs1 1 0.19 0.26 0.08
192 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
193 INT268627 Ptpn2 Positive_regulation of Gsk3b 1 0.02 1.7 0.08
194 INT110377 Binding of Ncoa1 and Pparg 1 0.02 0.26 0.08
195 INT115933 U Regulation of PLCB1 1 0.00 0.3 0.08
196 INT294302 PROK1 Positive_regulation of Localization of IL11 1 0.40 0.36 0.08
197 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08
198 INT188361 Il4 Positive_regulation of Socs1 1 0.14 0.15 0.08
199 INT294308 PROKR1 Regulation of Gene_expression of IL11 1 0.34 0 0.08
200 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24
2 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5
3 INT17915 Gene_expression of Insr 141 0.75 47.45 48.59
4 INT8691 Localization of Insr 85 0.80 9.27 30.32
5 INT5300 Regulation of Insr 54 0.60 11.33 29.26
6 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
7 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
8 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
9 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
10 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51
11 INT109031 Positive_regulation of Eif2ak3 44 0.69 21.11 14.72
12 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35
13 INT109034 Gene_expression of Eif2ak3 37 0.77 17.11 14.19
14 INT36177 Binding of Alms1 70 0.31 35.47 13.81
15 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
16 INT14768 Negative_regulation of Positive_regulation of Insr 16 0.56 5.51 13.59
17 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
18 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
19 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
20 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
21 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
22 INT144391 Gene_expression of RETN 42 0.75 40.48 10.47
23 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28
24 INT150678 Positive_regulation of Gene_expression of Eif2ak3 17 0.69 6.64 8.99
25 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
26 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
27 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
28 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
29 INT30920 Positive_regulation of Gene_expression of Insr 14 0.66 2.91 7.32
30 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
31 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
32 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16
33 INT24622 Positive_regulation of Localization of Insr 15 0.69 0.32 6.85
34 INT53871 Gene_expression of Socs1 32 0.71 22.83 6.21
35 INT67609 Binding of Pparg 17 0.46 9.53 6.06
36 INT36757 Gene_expression of Eif2ak3 4 0.74 0.15 6.06
37 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
38 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
39 INT32611 Phosphorylation of Insr 13 0.80 4.18 5.77
40 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
41 INT88286 Phosphorylation of Atf2 11 0.66 1.93 5.69
42 INT14769 Positive_regulation of Positive_regulation of Insr 10 0.43 2.66 5.55
43 INT85789 Gene_expression of Prlh 10 0.78 4.5 5.47
44 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4
45 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86
46 INT88282 Positive_regulation of Phosphorylation of Atf2 8 0.44 1.77 4.85
47 INT137336 Phosphorylation of Eif2ak3 14 0.79 4.72 4.78
48 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75
49 INT171011 Localization of RETN 12 0.73 19.2 4.64
50 INT24620 Negative_regulation of Gene_expression of Insr 14 0.39 6.98 4.61
51 INT94277 Positive_regulation of Gene_expression of Egr2 7 0.49 0.69 4.4
52 INT66366 Positive_regulation of Gsk3b 15 0.68 6.56 4.27
53 INT51084 Binding of Insr 13 0.30 4.25 4.23
54 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22
55 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21
56 INT83035 Binding of INSR 16 0.47 9.29 4.11
57 INT5602 Positive_regulation of Eif2ak3 9 0.66 0 4.04
58 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
59 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
60 INT217102 Gene_expression of Egr2 50 0.78 10.91 3.89
61 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
62 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83
63 INT108761 Localization of Alms1 24 0.70 13.92 3.74
64 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
65 INT17379 Positive_regulation of Prlh 6 0.64 0.58 3.68
66 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
67 INT77251 Positive_regulation of Atf2 8 0.70 2.45 3.62
68 INT8781 Regulation of Prlh 6 0.45 0.67 3.58
69 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53
70 INT78845 Binding of Pparg 16 0.44 11.67 3.53
71 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48
72 INT10116 Localization of INSR 11 0.57 5.43 3.48
73 INT14060 Negative_regulation of Negative_regulation of Insr 6 0.53 3.53 3.44
74 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
75 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
76 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
77 INT66367 Gene_expression of Gsk3b 16 0.45 9.75 3.07
78 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
79 INT90289 Positive_regulation of Gene_expression of Gpx1 10 0.17 8.07 3.05
80 INT200670 Gene_expression of AKT2 25 0.75 16.25 3
81 INT159709 Binding of ERAP1 12 0.47 3.42 2.91
82 INT85787 Transcription of Prlh 4 0.53 1.77 2.7
83 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
84 INT5863 Positive_regulation of Egr2 7 0.40 1.44 2.64
85 INT88285 Transcription of Atf2 4 0.36 1.56 2.62
86 INT69007 Binding of Cebpb 10 0.48 2.21 2.6
87 INT87395 Binding of Ccr5 5 0.29 2.5 2.6
88 INT203819 Binding of Eif2ak3 9 0.37 5.94 2.57
89 INT15695 Positive_regulation of EIF2AK3 12 0.67 7.01 2.56
90 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55
91 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5
92 INT52326 Negative_regulation of Atf2 7 0.45 0.94 2.5
93 INT172179 Positive_regulation of Gene_expression of IL11 7 0.55 4.29 2.43
94 INT125138 Positive_regulation of RETN 13 0.67 11.94 2.34
95 INT59818 Negative_regulation of PLCB1 7 0.57 2.24 2.28
96 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
97 INT184054 Negative_regulation of Gene_expression of Socs1 7 0.53 9.18 2.22
98 INT36758 Positive_regulation of Gene_expression of Eif2ak3 1 0.48 0 2.21
99 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
100 INT78844 Regulation of Pparg 6 0.41 4 2.19
101 INT24621 Regulation of Gene_expression of Insr 9 0.42 2.68 2.18
102 INT96743 Transcription of Ccr5 2 0.54 2.72 2.17
103 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
104 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
105 INT31006 Regulation of Localization of Insr 7 0.50 0.2 2.05
106 INT36755 Positive_regulation of Localization of Eif2ak3 1 0.48 0 1.97
107 INT36756 Localization of Eif2ak3 1 0.71 0 1.96
108 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95
109 INT150675 Regulation of Gene_expression of Eif2ak3 3 0.40 1.11 1.93
110 INT184042 Negative_regulation of Socs1 9 0.46 8.1 1.88
111 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87
112 INT217094 Positive_regulation of Egr2 17 0.69 5.31 1.87
113 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
114 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
115 INT87394 Negative_regulation of Ccr5 3 0.32 1.3 1.74
116 INT36759 Regulation of Gene_expression of Eif2ak3 1 0.59 0 1.74
117 INT184068 Positive_regulation of Socs1 7 0.51 4.03 1.73
118 INT218303 Protein_catabolism of INSR 3 0.29 0.67 1.73
119 INT232645 Transcription of INSR 2 0.09 1.19 1.71
120 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7
121 INT155006 Regulation of RETN 9 0.45 7.31 1.7
122 INT254250 Regulation of Socs1 5 0.06 3.04 1.66
123 INT117438 Positive_regulation of Gene_expression of Pparg 11 0.69 8 1.63
124 INT109033 Positive_regulation of Positive_regulation of Eif2ak3 2 0.45 2.36 1.59
125 INT85786 Localization of Prlh 3 0.75 0.87 1.57
126 INT231917 Gene_expression of Cebpb 10 0.25 4.45 1.56
127 INT67869 Transcription of Gpx1 3 0.68 0.67 1.56
128 INT184052 Localization of Socs1 3 0.59 4.07 1.54
129 INT29582 Negative_regulation of BBS9 8 0.57 8.3 1.48
130 INT110444 Positive_regulation of Atf2 7 0.50 2 1.48
131 INT150677 Negative_regulation of Eif2ak3 9 0.58 6.24 1.46
132 INT215864 Localization of Eif2ak3 5 0.75 3.26 1.36
133 INT18337 Transcription of Eif2ak3 3 0.68 0 1.36
134 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
135 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
136 INT155007 Positive_regulation of Gene_expression of RETN 4 0.27 9.17 1.3
137 INT106423 Binding of IL11 6 0.37 2.16 1.27
138 INT130207 Phosphorylation of ATF2 5 0.60 1.34 1.25
139 INT127900 Phosphorylation of EIF2AK3 14 0.80 7.99 1.22
140 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22
141 INT59815 Positive_regulation of PLCB1 9 0.67 1.12 1.22
142 INT171041 Positive_regulation of IL11 5 0.55 2.49 1.22
143 INT70673 Regulation of IL11 5 0.45 2.89 1.2
144 INT160054 Localization of AKT2 4 0.73 1.93 1.18
145 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16
146 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
147 INT134036 Regulation of Gsk3b 4 0.60 1.42 1.15
148 INT106339 Positive_regulation of Phosphorylation of Insr 1 0.49 0 1.12
149 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11
150 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11
151 INT85788 Negative_regulation of Prlh 5 0.54 0.95 1.09
152 INT32354 Negative_regulation of Regulation of Insr 3 0.33 0.13 1.08
153 INT144427 Transcription of Ccnd1 10 0.41 7.89 1.07
154 INT137338 Regulation of Eif2ak3 8 0.45 5.5 1.07
155 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06
156 INT207583 Negative_regulation of RETN 13 0.43 6.97 1.05
157 INT130209 Positive_regulation of Phosphorylation of ATF2 3 0.36 1.15 1.03
158 INT98817 Regulation of Pparg 3 0.26 1.62 1.03
159 INT89887 Regulation of Gene_expression of Gpx1 3 0.32 0.8 1.02
160 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02
161 INT116646 Regulation of Negative_regulation of Gsk3b 2 0.44 0.39 0.99
162 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96
163 INT83983 Phosphorylation of Atf2 6 0.63 2 0.95
164 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
165 INT87396 Negative_regulation of Gene_expression of Ccr5 1 0.12 1.02 0.92
166 INT173514 Negative_regulation of Gene_expression of Alms1 3 0.06 3.49 0.91
167 INT59198 Regulation of Ccnd1 11 0.47 6.54 0.9
168 INT261360 Binding of Gsk3b 5 0.36 2.85 0.9
169 INT171027 Negative_regulation of Gene_expression of RETN 4 0.43 3.26 0.9
170 INT26868 Regulation of BBS9 2 0.44 0.71 0.9
171 INT83984 Positive_regulation of Positive_regulation of Atf2 1 0.44 0.48 0.89
172 INT160056 Positive_regulation of AKT2 3 0.48 1.43 0.88
173 INT41911 Regulation of Positive_regulation of Insr 2 0.21 0.32 0.88
174 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
175 INT240368 Positive_regulation of Localization of Eif2ak3 1 0.34 0.66 0.87
176 INT271605 Regulation of Gene_expression of AKT2 1 0.44 0.81 0.87
177 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86
178 INT91908 Regulation of Negative_regulation of Insr 1 0.03 0.81 0.86
179 INT229278 Positive_regulation of Cby1 5 0.67 8.07 0.85
180 INT131113 Negative_regulation of Ptk2 3 0.58 0.17 0.85
181 INT103400 Transcription of Pparg 2 0.67 3.15 0.85
182 INT109032 Negative_regulation of Positive_regulation of Eif2ak3 1 0.38 0.94 0.85
183 INT69913 Binding of ATF2 6 0.13 0.83 0.84
184 INT184014 Binding of Socs1 2 0.34 0.97 0.84
185 INT28236 Localization of BBS2 2 0.54 1.9 0.83
186 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82
187 INT156945 Positive_regulation of Negative_regulation of Gsk3b 6 0.38 4.58 0.82
188 INT274178 Binding of BBS2 1 0.27 2.12 0.82
189 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
190 INT66365 Positive_regulation of Gene_expression of Gsk3b 2 0.07 0.95 0.81
191 INT127899 Gene_expression of EIF2AK3 8 0.75 2.89 0.8
192 INT154053 Negative_regulation of Gene_expression of Eif2ak3 2 0.43 1.28 0.79
193 INT116644 Phosphorylation of Gsk3b 4 0.61 0.68 0.78
194 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77
195 INT127901 Positive_regulation of Gene_expression of EIF2AK3 3 0.49 1.8 0.77
196 INT144759 Regulation of Gene_expression of INSR 2 0.44 3.09 0.77
197 INT207582 Regulation of Gene_expression of RETN 1 0.45 3.48 0.77
198 INT171017 Localization of IL11 9 0.64 4.83 0.76
199 INT230493 Regulation of Binding of Alms1 3 0.12 1.89 0.76
200 INT145747 Regulation of ERAP1 1 0.25 0.19 0.76
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