GO:0045453

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Name bone resorption
Categary Process
Go Slim No
Go Link GO:0045453
Unique Molecular Interactions 472
Total Molecular Interactions 607
Total Single Events 4436
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for bone resorption. They are ordered first by their pain relevance and then by number of times they were reported for bone resorption. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
2 INT30134 Binding of TPP1 and S100A9 1 0.13 0.74 1.69
3 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
4 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
5 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
6 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
7 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
8 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
9 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
10 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
11 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
12 INT174468 IL7 Positive_regulation of Gene_expression of IL4 1 0.40 1.88 1.02
13 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
14 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1
15 INT143915 Src Regulation of Rbm39 1 0.03 0.18 0.99
16 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
17 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
18 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
19 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
20 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
21 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
22 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
23 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
24 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
25 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
26 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82
27 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82
28 INT193275 Phax Regulation of Pth 1 0.01 0.16 0.81
29 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
30 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
31 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77
32 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
33 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
34 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
35 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
36 INT148453 Gene_expression of Inhbe Positive_regulation of Src 1 0.06 0.68 0.72
37 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
38 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71
39 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7
40 INT187220 Il11 Positive_regulation of Gene_expression of Tnfsf11 1 0.13 0.86 0.69
41 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
42 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
43 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
44 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
45 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
46 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
47 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
48 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
49 INT302834 Cd4 Positive_regulation of Gene_expression of Il7 1 0.05 1.02 0.54
50 INT174467 IL7 Positive_regulation of IFNA1 1 0.11 1.53 0.53
51 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53
52 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52
53 INT3218 Adrb2 Positive_regulation of Localization of Ins1 1 0.10 0 0.52
54 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
55 INT66188 Binding of ADRB2 and CDSN 1 0.01 0 0.51
56 INT187227 Vip Negative_regulation of Gene_expression of Tnfsf11 1 0.35 1.23 0.51
57 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
58 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51
59 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
60 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
61 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
62 INT302845 Il7 Positive_regulation of Gene_expression of TNF 1 0.01 0.98 0.49
63 INT302820 Stat3 Regulation of Positive_regulation of Il7 1 0.04 1.03 0.49
64 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49
65 INT302823 Stat3 Regulation of Gene_expression of Il7 1 0.04 1.03 0.49
66 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
67 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
68 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
69 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
70 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
71 INT116934 OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
72 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
73 INT116937 Positive_regulation of OPRK1 Positive_regulation of Positive_regulation of SRC 1 0.20 0.17 0.46
74 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
75 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
76 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42
77 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
78 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
79 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
80 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
81 INT231753 Il7 Positive_regulation of TNF 1 0.03 0.66 0.39
82 INT167946 Binding of SRC and Stat5b 1 0.28 0 0.38
83 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
84 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
85 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
86 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
87 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
88 INT143917 Binding of Src and Arrb2 1 0.27 0.07 0.37
89 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
90 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
91 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37
92 INT143918 Binding of Src and Rbm39 1 0.02 0.07 0.36
93 INT99292 Pth Positive_regulation of Jun 1 0.10 0.13 0.36
94 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
95 INT285465 IL7 Positive_regulation of TNF 1 0.04 0.67 0.35
96 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
97 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
98 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
99 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
100 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
101 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
102 INT165764 Tnfsf11 Positive_regulation of Mapk3 1 0.17 1.08 0.33
103 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
104 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
105 INT165765 Tnfsf11 Positive_regulation of Nfkb1 1 0.01 1.07 0.33
106 INT165763 Tnfsf11 Positive_regulation of Phosphorylation of Mapk3 1 0.40 1.08 0.33
107 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
108 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
109 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
110 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
111 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32
112 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
113 INT263979 Binding of ADRB2 and ATF3 1 0.01 0.5 0.32
114 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32
115 INT187223 Il1 Positive_regulation of Gene_expression of Tnfsf11 1 0.09 0.64 0.32
116 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32
117 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31
118 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
119 INT174464 IL7 Positive_regulation of IL4 1 0.40 0.61 0.31
120 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31
121 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
122 INT118853 Negative_regulation of SRC Negative_regulation of Positive_regulation of STAT3 1 0.41 0.08 0.28
123 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
124 INT233781 Binding of PTH1R and SCT 1 0.18 0 0.27
125 INT118855 Binding of SRC and GNA14 1 0.01 0.13 0.27
126 INT215279 Siglec1 Regulation of Rac2 1 0.01 0.74 0.27
127 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27
128 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
129 INT301280 Il6 Positive_regulation of Gene_expression of Acp5 1 0.04 0.37 0.26
130 INT100680 IL4 Positive_regulation of SRC 1 0.42 0.66 0.26
131 INT16163 Pth Regulation of Gene_expression of Plast4 1 0.00 0.65 0.25
132 INT159991 Ctsk Positive_regulation of POMC 1 0.01 0.35 0.25
133 INT118857 PLCB1 Regulation of Phosphorylation of SRC 1 0.01 0.15 0.24
134 INT118858 PRKCA Regulation of Phosphorylation of SRC 1 0.10 0.15 0.24
135 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
136 INT118850 GNA14 Positive_regulation of Phosphorylation of SRC 1 0.02 0.15 0.23
137 INT29099 Binding of ADRB2 and PPAP2A 1 0.03 0.77 0.22
138 INT254281 Il4 Negative_regulation of Gene_expression of Acp5 1 0.02 0.41 0.22
139 INT174465 IL7 Positive_regulation of Gene_expression of TH1L 1 0.21 0.56 0.22
140 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
141 INT63201 PTH Positive_regulation of CD8A 1 0.45 0.29 0.22
142 INT63200 PTH Positive_regulation of IL2 1 0.24 0.29 0.22
143 INT173558 CTSK Positive_regulation of Protein_catabolism of COL5A2 1 0.00 0.53 0.22
144 INT174466 Binding of IL7 and Positive_regulation of Gene_expression of TH1L 1 0.21 0.55 0.22
145 INT60909 TPP1 Positive_regulation of Gh1 1 0.00 0 0.22
146 INT174462 IL7 Positive_regulation of TH1L 1 0.20 0.56 0.22
147 INT63194 PTH Positive_regulation of PGR 1 0.25 0.29 0.22
148 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21
149 INT132680 HNF1A Positive_regulation of Gene_expression of UGT1A6 1 0.30 0.08 0.21
150 INT301279 Tnfsf11 Regulation of Gene_expression of Mmp9 1 0.13 0.34 0.21
151 INT132679 HNF1A Regulation of Gene_expression of UGT1A6 1 0.16 0.08 0.21
152 INT171973 Tnfsf11 Positive_regulation of Gene_expression of Il1 1 0.06 0.21 0.21
153 INT171972 Tnfsf11 Positive_regulation of Gene_expression of Il6 1 0.08 0.21 0.21
154 INT301281 Tnfsf11 Regulation of Gene_expression of Clec5a 1 0.22 0.34 0.21
155 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21
156 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
157 INT244299 FFAR1 Positive_regulation of PTH1R 1 0.00 0.4 0.2
158 INT301290 Tnfsf11 Positive_regulation of Nfatc1 1 0.15 0.65 0.2
159 INT316370 Ang Positive_regulation of Xdh 1 0.07 0.62 0.2
160 INT301282 Tnfsf11 Positive_regulation of Traf6 1 0.10 0.65 0.2
161 INT355364 Regulation of PTHLH Positive_regulation of Tnfsf11 1 0.04 1.51 0.19
162 INT355363 PTHLH Positive_regulation of Tnfsf11 1 0.04 1.47 0.19
163 INT174472 IL4 Regulation of IL7 1 0.16 0.38 0.19
164 INT355365 CSF1 Positive_regulation of Tnfsf11 1 0.03 1.49 0.19
165 INT355366 Regulation of CSF1 Positive_regulation of Tnfsf11 1 0.02 1.5 0.19
166 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
167 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17
168 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
169 INT190628 Negative_regulation of Binding of Rab7 and Sirt1 1 0.33 0.62 0.17
170 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17
171 INT190637 Negative_regulation of Binding of Rab7 and Rnf115 1 0.25 0.68 0.17
172 INT217478 Binding of Tnfrsf11a and Traf6 1 0.39 1.22 0.17
173 INT190638 Binding of Rab7 and Sirt1 1 0.29 0.62 0.17
174 INT190630 Binding of Rab7 and Rnf115 1 0.22 0.68 0.17
175 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
176 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
177 INT301278 Nfatc1 Regulation of Acp5 1 0.05 0.19 0.15
178 INT188694 Traf6 Positive_regulation of Positive_regulation of Irf3 1 0.08 0.2 0.15
179 INT128705 Binding of Adrb2 and Ahsg 1 0.00 0.23 0.15
180 INT181997 TNFRSF11B Negative_regulation of CTSK 1 0.05 0.58 0.14
181 INT107889 Binding of Pthlh and Pth1r 1 0.06 0 0.14
182 INT124412 Binding of PTH and Pth 1 0.02 0.65 0.14
183 INT309779 PTH Negative_regulation of Gene_expression of COL5A2 1 0.00 0.52 0.14
184 INT148532 Binding of CCL3 and Tnfsf11 1 0.03 0.71 0.14
185 INT81992 IL1A Positive_regulation of Positive_regulation of Tnfsf11 1 0.05 0.27 0.13
186 INT301283 Nfatc1 Regulation of Ctsk 1 0.06 0.19 0.13
187 INT308964 Binding of Abn-CBD and Gpr55 1 0.02 0 0.13
188 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
189 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
190 INT346530 Binding of PTH1R and TFIP11 1 0.15 0 0.11
191 INT334254 Binding of Traf6 and Gtf3a 1 0.00 0.18 0.11
192 INT171390 Src Positive_regulation of Phosphorylation of Egfr 1 0.13 0 0.11
193 INT174463 IL7 Regulation of Gene_expression of IFNA1 1 0.04 0.21 0.11
194 INT171389 Src Positive_regulation of Positive_regulation of Mapk1 1 0.16 0 0.11
195 INT331562 Binding of Il7 and Trav6-3 1 0.05 0.49 0.11
196 INT301284 Tnfsf11 Positive_regulation of Localization of Nfatc1 1 0.16 0.32 0.11
197 INT171388 Src Positive_regulation of Phosphorylation of Gpbar1 1 0.05 0 0.11
198 INT276064 Src Regulation of Positive_regulation of Rpa1 1 0.02 0.18 0.11
199 INT93535 PTH Negative_regulation of Gene_expression of Tnfsf11 1 0.19 0.22 0.11
200 INT107909 Binding of Tnfsf11 and Tnfrsf22 1 0.01 2.12 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported for bone resorption. They are ordered first by their pain relevance and then by number of times they were reported in bone resorption. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
2 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
3 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
4 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26
5 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
6 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36
7 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
8 INT27627 Binding of Rac1 41 0.41 22.88 13.68
9 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
10 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7
11 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
12 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
13 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
14 INT22083 Regulation of Pth 55 0.62 22.32 8.9
15 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
16 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24
17 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45
18 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42
19 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
20 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35
21 INT153794 Gene_expression of Ctsk 51 0.77 24.99 7.28
22 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27
23 INT16720 Negative_regulation of Xdh 35 0.59 14 6.67
24 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33
25 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23
26 INT233812 Gene_expression of PTH1R 32 0.77 18.15 6.15
27 INT59384 Gene_expression of Il7 23 0.75 11.42 5.87
28 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
29 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47
30 INT100222 Binding of Src 9 0.26 5.41 5.37
31 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
32 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
33 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
34 INT62570 Binding of Pth 48 0.48 26.45 4.85
35 INT98453 Positive_regulation of Src 19 0.47 7.84 4.62
36 INT151230 Positive_regulation of IL7 14 0.37 11.89 4.56
37 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
38 INT4097 Localization of Pth 66 0.81 47.17 4.36
39 INT134646 Gene_expression of Tnfsf11 19 0.69 14.77 4.16
40 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
41 INT22223 Positive_regulation of Xdh 18 0.67 5.87 3.84
42 INT174477 Negative_regulation of IL7 11 0.47 10.35 3.69
43 INT122327 Regulation of Src 6 0.59 0.59 3.6
44 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
45 INT236824 Negative_regulation of Gene_expression of PTH1R 10 0.58 9.3 3.42
46 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
47 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
48 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39
49 INT137350 Phosphorylation of Src 13 0.45 4.14 3.32
50 INT58475 Localization of Rac1 12 0.75 5.94 3.2
51 INT28094 Binding of PTH 29 0.37 13.57 3.09
52 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08
53 INT302808 Positive_regulation of Gene_expression of Il7 8 0.15 6.59 3.06
54 INT41474 Gene_expression of ADRB2 10 0.75 1.56 2.94
55 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
56 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
57 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84
58 INT22194 Gene_expression of Xdh 20 0.75 10.03 2.83
59 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78
60 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
61 INT225253 Positive_regulation of Phosphorylation of Src 4 0.38 2.36 2.59
62 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55
63 INT172592 Positive_regulation of PTH1R 9 0.28 6.25 2.5
64 INT174481 Positive_regulation of Gene_expression of IL7 9 0.56 6.19 2.46
65 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
66 INT81989 Positive_regulation of Tnfsf11 11 0.54 7.57 2.4
67 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39
68 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39
69 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
70 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31
71 INT174801 Positive_regulation of Il7 5 0.15 4.76 2.31
72 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
73 INT159989 Positive_regulation of Ctsk 17 0.69 10.51 2.25
74 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
75 INT2544 Localization of PTH 39 0.81 30.55 2.22
76 INT224620 Positive_regulation of Gene_expression of Ctsk 13 0.68 8.35 2.21
77 INT30137 Negative_regulation of TPP1 5 0.37 0.96 2.2
78 INT70725 Negative_regulation of Binding of ADRB2 3 0.57 0.4 2.14
79 INT57258 Regulation of Gene_expression of IL7 9 0.36 4.28 2.12
80 INT146660 Negative_regulation of Ctsk 9 0.43 6.01 2.07
81 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
82 INT153775 Positive_regulation of CTSK 9 0.52 5.44 1.9
83 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
84 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
85 INT98464 Positive_regulation of Positive_regulation of SRC 10 0.67 5.71 1.86
86 INT40832 Localization of ADRB2 5 0.73 2.21 1.81
87 INT82609 Phosphorylation of SRC 17 0.80 6.45 1.7
88 INT19626 Regulation of Xdh 4 0.22 2.69 1.7
89 INT174480 Binding of IL7 3 0.38 4.55 1.69
90 INT30138 Binding of TPP1 1 0.16 0.74 1.69
91 INT146943 Gene_expression of Src 13 0.49 6.65 1.65
92 INT23609 Negative_regulation of Acp5 5 0.33 1.69 1.65
93 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
94 INT3343 Regulation of PTH 24 0.62 11.18 1.62
95 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
96 INT181963 Regulation of IL7 7 0.49 3.56 1.61
97 INT181962 Negative_regulation of Gene_expression of IL7 7 0.47 4.51 1.5
98 INT98455 Regulation of Src 4 0.20 1.76 1.48
99 INT105551 Transcription of Tnfsf11 6 0.69 4.21 1.38
100 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37
101 INT114715 Binding of SRC 8 0.36 4.26 1.32
102 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28
103 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
104 INT174482 Localization of IL7 5 0.64 2.84 1.23
105 INT23610 Gene_expression of Acp5 4 0.51 0.96 1.23
106 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
107 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
108 INT298979 Gene_expression of Traf6 5 0.31 1.75 1.21
109 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
110 INT105552 Positive_regulation of Transcription of Tnfsf11 3 0.31 2.94 1.17
111 INT61466 Positive_regulation of Acp5 15 0.66 10.17 1.16
112 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15
113 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
114 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15
115 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
116 INT41475 Positive_regulation of Localization of ADRB2 2 0.49 0.18 1.12
117 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
118 INT82214 Transcription of PTH 6 0.54 3.33 1.11
119 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
120 INT182005 Positive_regulation of Gene_expression of CTSK 7 0.52 4.01 1.08
121 INT233816 Negative_regulation of PTH1R 2 0.58 4.08 1.07
122 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
123 INT65093 Gene_expression of ACP5 8 0.56 2.1 1.02
124 INT210586 Negative_regulation of Positive_regulation of Tnfsf11 3 0.41 1.4 1.02
125 INT49796 Positive_regulation of Binding of Adrb2 1 0.00 0 1.02
126 INT52186 Positive_regulation of Positive_regulation of ADRB2 1 0.14 0 1.02
127 INT49795 Negative_regulation of Binding of Adrb2 1 0.00 0 1.02
128 INT132847 Negative_regulation of Localization of Tnfsf11 1 0.32 0.16 1.01
129 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
130 INT317504 Protein_catabolism of Src 1 0.49 0.13 0.97
131 INT209423 Negative_regulation of Gene_expression of Ctsk 4 0.41 2.4 0.96
132 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96
133 INT4096 Regulation of Localization of Pth 7 0.58 3.97 0.95
134 INT38036 Gene_expression of Rac2 4 0.57 3.74 0.95
135 INT15304 Regulation of Acp5 2 0.44 0.2 0.94
136 INT171963 Positive_regulation of Positive_regulation of Tnfsf11 3 0.42 2.44 0.93
137 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
138 INT22224 Positive_regulation of Positive_regulation of Xdh 3 0.42 0.87 0.92
139 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
140 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
141 INT309781 Positive_regulation of Gene_expression of PTH1R 2 0.46 1.88 0.87
142 INT14976 Negative_regulation of Adrb2 3 0.24 0.75 0.86
143 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
144 INT70726 Positive_regulation of Negative_regulation of ADRB2 1 0.49 0.2 0.86
145 INT42863 Regulation of Adrb2 1 0.11 1.02 0.85
146 INT42862 Regulation of Binding of Adrb2 1 0.15 1.03 0.85
147 INT311254 Localization of Acp5 2 0.76 3.24 0.81
148 INT118004 Positive_regulation of Gene_expression of SRC 13 0.49 11.05 0.8
149 INT264629 Localization of Rac1 8 0.72 5.7 0.79
150 INT294998 Positive_regulation of Gene_expression of Tnfsf11 5 0.62 2.98 0.79
151 INT143912 Localization of Src 4 0.48 2.51 0.78
152 INT33481 Positive_regulation of Gene_expression of Adrb2 2 0.48 0.38 0.78
153 INT174803 Localization of Il7 2 0.11 1.67 0.77
154 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
155 INT59385 Binding of Il7 3 0.36 0.48 0.76
156 INT231620 Negative_regulation of Gene_expression of Il7 2 0.17 1.61 0.76
157 INT159988 Localization of Ctsk 5 0.70 2.9 0.74
158 INT174794 Negative_regulation of Localization of Il7 1 0.08 1.2 0.74
159 INT174804 Positive_regulation of Localization of Il7 1 0.07 1.18 0.73
160 INT31778 Negative_regulation of Adrb2 2 0.07 1.34 0.72
161 INT165760 Positive_regulation of Binding of Tnfsf11 2 0.36 1.83 0.71
162 INT285644 Binding of Gpr55 2 0.20 0.12 0.7
163 INT115596 Regulation of Regulation of Rac1 1 0.36 0.29 0.7
164 INT185729 Negative_regulation of Gene_expression of Tnfsf11 3 0.52 2.07 0.69
165 INT67452 Positive_regulation of Regulation of ADRB2 1 0.41 0.26 0.68
166 INT329460 Gene_expression of Gpr55 1 0.49 1.16 0.68
167 INT244300 Localization of PTH1R 2 0.74 2.03 0.67
168 INT15301 Regulation of Transcription of Acp5 1 0.10 0.17 0.66
169 INT15306 Transcription of Acp5 1 0.15 0.17 0.66
170 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
171 INT188799 Positive_regulation of Protein_catabolism of Traf6 2 0.19 1.98 0.62
172 INT153773 Regulation of Gene_expression of CTSK 2 0.34 1.36 0.62
173 INT62067 Negative_regulation of Gene_expression of Pth 13 0.41 8.24 0.61
174 INT104632 Negative_regulation of Positive_regulation of Xdh 2 0.14 0.9 0.61
175 INT113042 Localization of IHH 1 0.70 0.77 0.61
176 INT264991 Positive_regulation of Localization of Tnfsf11 5 0.24 3.22 0.59
177 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
178 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57
179 INT65089 Positive_regulation of ACP5 4 0.50 1.67 0.57
180 INT38037 Regulation of Rac2 2 0.38 0.79 0.57
181 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
182 INT143910 Negative_regulation of Positive_regulation of Src 1 0.27 0.14 0.56
183 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55
184 INT38038 Negative_regulation of Rac2 1 0.36 0.79 0.55
185 INT43158 Regulation of TPP1 1 0.23 0 0.55
186 INT16012 Binding of Rac1 17 0.37 6.9 0.53
187 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
188 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
189 INT61464 Regulation of Acp5 2 0.59 0.72 0.51
190 INT207379 Regulation of Negative_regulation of Tnfsf11 2 0.28 1.7 0.5
191 INT227331 Binding of Xdh 5 0.29 1.83 0.49
192 INT163993 Gene_expression of Hnf1a 2 0.65 1.38 0.49
193 INT82608 Positive_regulation of Phosphorylation of SRC 3 0.49 1.28 0.48
194 INT85659 Gene_expression of TPP1 2 0.53 1.84 0.48
195 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
196 INT36770 Positive_regulation of Localization of Pth 14 0.70 10.42 0.46
197 INT302801 Positive_regulation of Positive_regulation of Il7 1 0.10 0.96 0.46
198 INT329464 Localization of Gpr55 1 0.47 0.77 0.46
199 INT81212 Negative_regulation of Transcription of Rac1 1 0.01 0 0.46
200 INT249504 Localization of Src 1 0.36 0.32 0.46
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