GO:0045454

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Name cell redox homeostasis
Categary Process
Go Slim No
Go Link GO:0045454
Unique Molecular Interactions 1011
Total Molecular Interactions 1490
Total Single Events 12530
Pain Genes Associated 46

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cell redox homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for cell redox homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
2 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
3 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
4 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
5 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
6 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
7 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
8 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
9 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
10 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
11 INT87267 Binding of BMP8B and KRIT1 1 0.06 0.16 2.69
12 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
13 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
14 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
15 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
16 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
17 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
18 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
19 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
20 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
21 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
22 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
23 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
24 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
25 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
26 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
27 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
28 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
29 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
30 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
31 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
32 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
33 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
34 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
35 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
36 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
37 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
38 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
39 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
40 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
41 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
42 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
43 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
44 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
45 INT87266 Negative_regulation of Binding of BMP8B and KRIT1 1 0.05 0.07 1.37
46 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
47 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
48 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
49 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
50 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
51 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
52 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
53 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
54 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
55 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
56 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
57 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
58 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
59 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
60 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
61 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
62 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
63 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
64 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
65 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
66 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
67 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
68 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
69 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
70 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
71 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
72 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
73 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
74 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
75 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
76 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
77 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
78 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
79 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
80 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
81 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
82 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
83 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
84 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
85 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
86 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
87 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
88 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
89 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
90 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
91 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9
92 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
93 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
94 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
95 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
96 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
97 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
98 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
99 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
100 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
101 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
102 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
103 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
104 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
105 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
106 INT100283 TXN Negative_regulation of Gene_expression of POMC 1 0.54 0.5 0.85
107 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
108 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
109 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
110 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83
111 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
112 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
113 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
114 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
115 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
116 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
117 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
118 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
119 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
120 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
121 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
122 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
123 INT34825 Aap Negative_regulation of Gsr 1 0.01 0.3 0.75
124 INT31776 Positive_regulation of Gclc Positive_regulation of G6pd 1 0.29 0.19 0.75
125 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
126 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
127 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
128 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
129 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
130 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
131 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
132 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
133 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
134 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
135 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
136 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
137 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
138 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
139 INT87275 KRIT1 Regulation of Oprd1 1 0.01 0.08 0.72
140 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
141 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
142 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
143 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
144 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
145 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
146 INT207544 Qsox1 Regulation of Oprm1 1 0.08 0.06 0.7
147 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
148 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
149 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
150 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
151 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69
152 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
153 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
154 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
155 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
156 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
157 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
158 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
159 INT207547 Sp1 Regulation of Qsox1 1 0.05 0.06 0.67
160 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
161 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
162 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
163 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66
164 INT118568 Binding of Ddit3 and Atf6 1 0.33 0.85 0.66
165 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
166 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
167 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
168 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
169 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
170 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64
171 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
172 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63
173 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
174 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
175 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
176 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
177 INT112032 Positive_regulation of Oprm1 Positive_regulation of Pdia3 1 0.44 0.13 0.62
178 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62
179 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 0.00 0.15 0.62
180 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
181 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61
182 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
183 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
184 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
185 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
186 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
187 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
188 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58
189 INT38131 Pag1 Negative_regulation of Gsr 1 0.01 0.72 0.58
190 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
191 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
192 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
193 INT5416 Negative_regulation of Penk Positive_regulation of Pdia4 1 0.03 0.09 0.58
194 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
195 INT347362 RYBP Regulation of Gene_expression of GSR 1 0.01 0 0.57
196 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
197 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57
198 INT142312 Lalba Negative_regulation of Localization of Il6 1 0.23 0.73 0.57
199 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57
200 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported for cell redox homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in cell redox homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 365 0.81 241.78 105.78
9 INT19511 Localization of Il6 212 0.81 118.17 67.67
10 INT11937 Localization of Il6 228 0.81 139.83 64.39
11 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
12 INT10706 Regulation of Il6 150 0.62 93.23 62.34
13 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
14 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
15 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
16 INT9210 Regulation of IL6 166 0.62 125.61 49.95
17 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
18 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
19 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
20 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
21 INT9655 Regulation of Il6 98 0.62 70.92 31.95
22 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
23 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
24 INT86437 Binding of IL6 154 0.48 121.22 29.3
25 INT51474 Binding of Il6 55 0.48 44.99 20.52
26 INT49985 Transcription of Il6 62 0.72 40.13 20.29
27 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
28 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
29 INT61626 Transcription of IL6 73 0.72 42.04 17.86
30 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
31 INT134298 Gene_expression of Ptges2 96 0.54 56.52 17.19
32 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
33 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
34 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
35 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
36 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25
37 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
38 INT54763 Binding of Il6 82 0.48 63.27 12.89
39 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
40 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
41 INT16870 Negative_regulation of Gsr 27 0.59 10.28 11.81
42 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
43 INT50933 Transcription of Il6 38 0.72 24.31 11.58
44 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
45 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19
46 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
47 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37
48 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
49 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28
50 INT63701 Localization of KRIT1 11 0.78 2.02 9.17
51 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99
52 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
53 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
54 INT9818 Positive_regulation of Pdia4 12 0.34 0.67 6.65
55 INT142904 Negative_regulation of Ptges2 14 0.47 9.49 6.15
56 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
57 INT162328 Regulation of Ptges2 21 0.19 12.07 5.56
58 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47
59 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
60 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
61 INT128161 Gene_expression of DDIT3 20 0.75 17.14 5.13
62 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
63 INT38251 Negative_regulation of Gclc 7 0.57 1.37 5.06
64 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01
65 INT134297 Positive_regulation of Gene_expression of Ptges2 22 0.41 13.12 4.97
66 INT62291 Gene_expression of PTGES2 14 0.68 8.34 4.75
67 INT100772 Negative_regulation of TXNRD1 10 0.41 3.47 4.74
68 INT131808 Localization of Apex1 2 0.16 13.46 4.61
69 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43
70 INT45725 Binding of Pdia3 8 0.47 3.61 4.42
71 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
72 INT118565 Gene_expression of Ddit3 35 0.75 23.62 4.32
73 INT138698 Gene_expression of Txn1 15 0.77 11.71 4.24
74 INT138701 Positive_regulation of Gene_expression of Txn1 10 0.50 9.16 4.03
75 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02
76 INT134296 Positive_regulation of Ptges2 20 0.19 14.85 3.8
77 INT26233 Binding of GSR 45 0.46 18.22 3.74
78 INT112 Gene_expression of Pdia3 11 0.74 0.18 3.74
79 INT164540 Localization of Aifm1 15 0.46 13.87 3.65
80 INT35683 Gene_expression of Gsr 24 0.46 16.94 3.6
81 INT3842 Positive_regulation of Gsr 14 0.69 3.48 3.55
82 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
83 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
84 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48
85 INT142483 Positive_regulation of Gene_expression of DDIT3 15 0.67 11.39 3.47
86 INT137634 Localization of Aifm1 17 0.80 11.8 3.45
87 INT91070 Regulation of GSR 27 0.59 16.64 3.42
88 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
89 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
90 INT60610 Negative_regulation of Gsr 7 0.26 6.88 3.32
91 INT250581 Gene_expression of SELS 4 0.78 47.37 3.27
92 INT139355 Regulation of Gene_expression of Ptges2 11 0.17 6.37 3.19
93 INT41312 Gene_expression of Gsr 13 0.44 4.62 3.18
94 INT90289 Positive_regulation of Gene_expression of Gpx1 10 0.17 8.07 3.05
95 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
96 INT12796 Binding of DLD 20 0.36 6.71 3.02
97 INT83351 Positive_regulation of Gene_expression of GSR 15 0.64 12.03 2.97
98 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
99 INT7142 Positive_regulation of DLD 22 0.60 7.69 2.76
100 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7
101 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
102 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
103 INT91349 Negative_regulation of Binding of Pdia3 1 0.57 1.12 2.59
104 INT145126 Positive_regulation of GLRX 5 0.12 4.55 2.53
105 INT139354 Negative_regulation of Gene_expression of Ptges2 11 0.23 4.28 2.51
106 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48
107 INT195005 Positive_regulation of Aifm1 11 0.29 7.92 2.46
108 INT151574 Gene_expression of Aifm1 5 0.62 3.63 2.34
109 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
110 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29
111 INT79658 Transcription of GSR 8 0.68 3.59 2.19
112 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
113 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
114 INT69703 Gene_expression of TXN 20 0.71 3.57 2.01
115 INT209439 Localization of Gsr 8 0.26 3.25 2
116 INT100897 Positive_regulation of Gene_expression of GCLC 9 0.68 1.84 1.99
117 INT119680 Positive_regulation of Pdia3 4 0.31 2.36 1.97
118 INT58432 Positive_regulation of Gsr 12 0.70 9.4 1.94
119 INT110580 Regulation of Transcription of GSR 2 0.27 0.98 1.94
120 INT5415 Negative_regulation of Pdia4 6 0.36 0.94 1.93
121 INT141166 Positive_regulation of Gene_expression of Ddit3 15 0.56 10.32 1.92
122 INT12895 Negative_regulation of Positive_regulation of Pdia4 2 0.14 0 1.91
123 INT62290 Positive_regulation of Gene_expression of PTGES2 5 0.28 3.14 1.88
124 INT173419 Gene_expression of Ddit3 16 0.75 23.31 1.87
125 INT20094 Binding of Pdia3 3 0.31 1.26 1.87
126 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
127 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
128 INT48218 Gene_expression of KRIT1 16 0.75 7.59 1.8
129 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
130 INT156005 Positive_regulation of Gene_expression of Aifm1 1 0.36 1.56 1.75
131 INT184154 Transcription of Ptges2 4 0.20 2.4 1.71
132 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7
133 INT240060 Binding of NME8 1 0.42 3.85 1.69
134 INT16686 Regulation of Pdia4 2 0.09 0.26 1.68
135 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
136 INT41395 Positive_regulation of Gclc 9 0.61 1.34 1.66
137 INT67869 Transcription of Gpx1 3 0.68 0.67 1.56
138 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55
139 INT100286 Localization of TXN 21 0.73 5.13 1.48
140 INT87272 Binding of KRIT1 4 0.47 1.2 1.48
141 INT125800 Gene_expression of P4HB 5 0.47 5.4 1.47
142 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
143 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
144 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
145 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
146 INT93735 Gene_expression of P4hb 6 0.49 4.63 1.39
147 INT141037 Positive_regulation of Aifm1 3 0.45 3.32 1.38
148 INT164541 Negative_regulation of Localization of Aifm1 3 0.27 4.51 1.38
149 INT128160 Regulation of DDIT3 3 0.57 2.45 1.29
150 INT195013 Positive_regulation of Localization of Aifm1 1 0.27 4.18 1.29
151 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27
152 INT37646 Negative_regulation of Aifm1 2 0.47 1.28 1.26
153 INT118682 Positive_regulation of KRIT1 4 0.67 1.25 1.24
154 INT165800 Positive_regulation of Ddit3 17 0.67 11.69 1.21
155 INT116144 Positive_regulation of Positive_regulation of Ddit3 2 0.41 2.95 1.2
156 INT110582 Localization of GSR 10 0.79 4.03 1.19
157 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
158 INT93619 Localization of PTGES2 2 0.04 1.88 1.17
159 INT168675 Binding of P4HB 3 0.20 1.98 1.11
160 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
161 INT100892 Positive_regulation of GCLC 8 0.68 3.44 1.08
162 INT141036 Negative_regulation of Aifm1 1 0.00 1.26 1.07
163 INT47213 Negative_regulation of Binding of Pdia3 1 0.38 0.15 1.03
164 INT152407 Negative_regulation of Gene_expression of DDIT3 3 0.40 0.87 1.02
165 INT89887 Regulation of Gene_expression of Gpx1 3 0.32 0.8 1.02
166 INT87273 Positive_regulation of Localization of KRIT1 1 0.67 0.1 1.02
167 INT152408 Binding of DDIT3 3 0.35 2.06 1
168 INT134260 Negative_regulation of Transcription of Il6 2 0.25 1.39 0.99
169 INT119682 Positive_regulation of Positive_regulation of Pdia3 1 0.10 0.22 0.99
170 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
171 INT169472 Gene_expression of PDIA2 15 0.58 7.88 0.96
172 INT132617 Regulation of Gsr 3 0.42 1.55 0.96
173 INT116140 Localization of Ddit3 2 0.57 1.94 0.96
174 INT66673 Regulation of Pdia3 5 0.42 2.14 0.93
175 INT61613 Regulation of DLD 6 0.34 2.96 0.92
176 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
177 INT150117 Localization of P4HB 3 0.78 3.81 0.91
178 INT69705 Positive_regulation of TXN 8 0.63 2.35 0.89
179 INT134299 Localization of Ptges2 4 0.60 5.93 0.89
180 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87
181 INT94194 Transcription of Gclc 1 0.58 0.53 0.87
182 INT29762 Negative_regulation of P4hb 4 0.21 1.41 0.86
183 INT112533 Localization of P4hb 5 0.50 1.82 0.85
184 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
185 INT31775 Positive_regulation of Gclc 3 0.38 0.52 0.84
186 INT192851 Phosphorylation of Il6 7 0.68 3.12 0.82
187 INT110859 Negative_regulation of Positive_regulation of TXNRD1 1 0.41 0.65 0.82
188 INT20097 Positive_regulation of Binding of Pdia3 1 0.10 0 0.8
189 INT195007 Positive_regulation of Gene_expression of Aifm1 1 0.40 4.75 0.79
190 INT210193 Binding of TXN 31 0.44 6.88 0.78
191 INT195016 Gene_expression of Aifm1 8 0.45 5.92 0.78
192 INT300843 Regulation of Transcription of Il6 3 0.37 3.4 0.76
193 INT170388 Gene_expression of Magt1 17 0.47 8.21 0.75
194 INT48909 Localization of DLD 9 0.63 3.37 0.75
195 INT168432 Negative_regulation of Positive_regulation of Gpx1 4 0.40 2.89 0.75
196 INT52196 Negative_regulation of Regulation of Il6 3 0.42 3.42 0.74
197 INT115293 Regulation of Gene_expression of TXN 2 0.19 0.78 0.73
198 INT71599 Phosphorylation of KRIT1 1 0.79 0 0.73
199 INT158354 Negative_regulation of Binding of Il6 2 0.20 2.21 0.71
200 INT170772 Negative_regulation of Gene_expression of GSR 8 0.41 3.05 0.7
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