GO:0045509

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Name interleukin-27 receptor activity
Categary Function
Go Slim No
Go Link GO:0045509
Unique Molecular Interactions 13
Total Molecular Interactions 23
Total Single Events 65
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-27 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-27 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
2 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67
3 INT172096 Binding of HLA-E and Il27ra 2 0.01 1.32 0.48
4 INT172094 Binding of Atp9a and Il27ra 1 0.01 0.98 0.4
5 INT94474 Binding of Cd3e and Il27ra 1 0.02 0 0.34
6 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23
7 INT226720 Binding of Prkca and Il27ra 1 0.00 0.52 0.2
8 INT226756 Positive_regulation of Binding of Prkca and Il27ra 1 0.00 0.52 0.2
9 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18
10 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17
11 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17
12 INT188470 Binding of Gpi1 and Il27ra 1 0.00 0.86 0.16
13 INT294316 IL6ST Positive_regulation of Gene_expression of IL11 1 0.22 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-27 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-27 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67
2 INT50994 Binding of Il27ra 5 0.11 1.77 2.15
3 INT133422 Binding of IL6ST 10 0.40 4.9 1.49
4 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21
5 INT231793 Negative_regulation of Il27ra 4 0.08 3.04 0.98
6 INT188230 Negative_regulation of IL6ST 3 0.33 0.49 0.45
7 INT239027 Regulation of Regulation of Il27ra 1 0.02 1.03 0.41
8 INT239031 Regulation of Il27ra 1 0.05 1.03 0.41
9 INT174433 Gene_expression of Il27ra 1 0.06 1.21 0.41
10 INT136518 Regulation of IL6ST 2 0.29 0.31 0.36
11 INT136520 Positive_regulation of Regulation of IL6ST 1 0.09 0.08 0.13
12 INT254238 Positive_regulation of Il27ra 3 0.06 0.93 0.12
13 INT206151 Positive_regulation of Gene_expression of IL6ST 2 0.24 0.35 0.06
14 INT294329 Regulation of Gene_expression of IL6ST 1 0.22 0 0.05
15 INT294344 Localization of IL6ST 1 0.39 0 0.04
16 INT206153 Phosphorylation of IL6ST 1 0.22 0.05 0
17 INT206156 Positive_regulation of Phosphorylation of IL6ST 1 0.14 0.05 0
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