GO:0045542

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Name positive regulation of cholesterol biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045542
Unique Molecular Interactions 62
Total Molecular Interactions 84
Total Single Events 670
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cholesterol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cholesterol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25
2 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
3 INT21233 Ngf Regulation of Fgf1 1 0.46 0.09 0.79
4 INT348396 Binding of LPAR5 and Fdps 1 0.07 0.81 0.69
5 INT348381 Fdps Positive_regulation of Lpar5 1 0.07 0.75 0.64
6 INT348399 Fdps Positive_regulation of LPAR5 1 0.08 0.75 0.64
7 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
8 INT205567 Regulation of Binding of Fgf1 and Chat 1 0.29 0.28 0.41
9 INT205566 Binding of Fgf1 and Chat 1 0.24 0.28 0.41
10 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29
11 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29
12 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
13 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22
14 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21
15 INT110274 Binding of Fdps and Plin2 1 0.00 0.22 0.18
16 INT347338 Binding of Fgf1 and S100a9 1 0.26 0.46 0.15
17 INT347331 Binding of Fgf1 and S100a8 1 0.26 0.46 0.15
18 INT157275 Binding of PRKAA1 and Adipoq 1 0.01 1.13 0.15
19 INT157273 Adipoq Positive_regulation of PRKAA1 1 0.03 1.16 0.14
20 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12
21 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09
22 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08
23 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08
24 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08
25 INT157264 PPARA Positive_regulation of PRKAA1 1 0.03 0.92 0.08
26 INT157271 Adipor1 Positive_regulation of PRKAA1 1 0.01 0.89 0.08
27 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 0.10 0.67 0.08
28 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 0.08 0.62 0.08
29 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08
30 INT301656 Ins1 Positive_regulation of Srebf1 1 0.02 0.73 0.07
31 INT262187 Nr1i2 Positive_regulation of Gene_expression of Abcg1 1 0.24 0.21 0.06
32 INT340568 Fgf1 Positive_regulation of Mapk1 1 0.06 1.02 0.04
33 INT262195 Nr1i2 Positive_regulation of Srebf1 1 0.08 0.18 0.03
34 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03
35 INT264979 Binding of POR and BAG3 1 0.15 0.38 0
36 INT280619 Ins1 Positive_regulation of Srebf1 1 0.04 0.16 0
37 INT203978 Binding of Srebf1 and Scap 1 0.01 0.26 0
38 INT260269 Binding of FGF1 and FGFBP1 1 0.47 0.94 0
39 INT65036 Fgf1 Regulation of Anxa5 1 0.01 0.35 0
40 INT215345 Positive_regulation of Binding of Srebf1 and Tbp 1 0.05 0.16 0
41 INT222474 Binding of Fgf1 and Ecm1 1 0.00 0.62 0
42 INT178433 Fgf1 Positive_regulation of Mapk14 1 0.02 0.65 0
43 INT215343 Binding of Srebf1 and Tbp 1 0.04 0.16 0
44 INT314683 NUDT6 Positive_regulation of FGF1 1 0.02 1.17 0
45 INT341308 Negative_regulation of Npc1 Positive_regulation of Gene_expression of Srebf1 1 0.31 1.48 0
46 INT65035 Fgf1 Regulation of F2 1 0.07 0.34 0
47 INT324660 Vash1 Regulation of Gene_expression of Fgf1 1 0.14 0.44 0
48 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0
49 INT307213 Srebf1 Regulation of Gene_expression of Fasn 1 0.05 0.06 0
50 INT307219 Mlxipl Regulation of Srebf1 1 0.07 0.12 0
51 INT307216 Ppara Regulation of Srebf1 1 0.22 0.12 0
52 INT260265 Binding of FGF1 and FGFR1 1 0.45 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cholesterol biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cholesterol biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT92493 Gene_expression of Fdps 19 0.75 11.28 10.08
2 INT37139 Negative_regulation of Fdps 9 0.38 4.33 4.46
3 INT48143 Gene_expression of Fgf1 32 0.78 8.2 3.72
4 INT111820 Positive_regulation of Fdps 10 0.42 10.63 3.01
5 INT114702 Gene_expression of Fgf1 34 0.74 17.39 2.96
6 INT179867 Localization of Fdps 7 0.63 3.62 2.86
7 INT38384 Regulation of Por 5 0.47 0.58 2.4
8 INT65034 Regulation of Fgf1 7 0.61 2.42 2.34
9 INT12131 Gene_expression of POR 17 0.77 9.42 2.17
10 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95
11 INT73816 Positive_regulation of Fgf1 5 0.70 2.31 1.49
12 INT63328 Binding of Fgf1 10 0.37 1.5 1.4
13 INT92966 Positive_regulation of FGF1 4 0.38 2.25 1.33
14 INT151 Positive_regulation of Por 5 0.62 0.42 1.31
15 INT49013 Gene_expression of Por 6 0.75 2.19 1.22
16 INT115821 Transcription of Por 1 0.33 0.51 1.02
17 INT49012 Regulation of Gene_expression of Por 1 0.44 0 1.02
18 INT114704 Positive_regulation of Fgf1 13 0.50 8.89 0.89
19 INT86474 Negative_regulation of Fgf1 6 0.58 0.64 0.88
20 INT176174 Gene_expression of Srebf1 16 0.66 6.53 0.82
21 INT94833 Gene_expression of FGF1 4 0.53 2.01 0.81
22 INT73815 Localization of Fgf1 10 0.80 1.73 0.69
23 INT58960 Regulation of POR 5 0.25 1.04 0.68
24 INT37252 Binding of Fdps 4 0.20 3.57 0.63
25 INT176181 Positive_regulation of Srebf1 10 0.42 3.69 0.62
26 INT104233 Positive_regulation of Gene_expression of Fgf1 2 0.63 1.79 0.62
27 INT94834 Positive_regulation of Gene_expression of FGF1 2 0.48 1.82 0.56
28 INT184690 Transcription of Fgf1 6 0.51 1.97 0.55
29 INT40164 Binding of Por 2 0.37 0.5 0.51
30 INT239289 Gene_expression of Abcg1 3 0.31 2.27 0.5
31 INT203949 Regulation of Srebf1 8 0.38 3.19 0.48
32 INT348392 Positive_regulation of Phosphorylation of Fdps 1 0.16 0.59 0.47
33 INT348389 Phosphorylation of Fdps 1 0.26 0.59 0.47
34 INT191583 Positive_regulation of Gene_expression of Fdps 2 0.15 1.55 0.44
35 INT348395 Negative_regulation of Gene_expression of Fdps 1 0.16 0.49 0.42
36 INT265 Negative_regulation of Por 4 0.59 0.34 0.41
37 INT159051 Positive_regulation of Transcription of Fgf1 1 0.45 0.71 0.41
38 INT159052 Transcription of Fgf1 1 0.62 0.71 0.41
39 INT344684 Positive_regulation of Gene_expression of Abcg1 1 0.10 0.95 0.38
40 INT133874 Negative_regulation of Gene_expression of Fgf1 2 0.24 2.82 0.36
41 INT82817 Localization of FGF1 2 0.60 2.12 0.36
42 INT12249 Binding of POR 5 0.35 2.76 0.35
43 INT252961 Localization of Fgf1 3 0.27 5.91 0.35
44 INT176192 Negative_regulation of Positive_regulation of Srebf1 2 0.26 0.95 0.35
45 INT301529 Positive_regulation of Gene_expression of Srebf1 7 0.42 1.59 0.32
46 INT114699 Positive_regulation of Gene_expression of Fgf1 4 0.32 2.21 0.29
47 INT226115 Positive_regulation of PRKAA1 2 0.15 0.45 0.29
48 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27
49 INT183120 Regulation of FGF1 3 0.10 2.53 0.23
50 INT332259 Positive_regulation of Positive_regulation of Fgf1 1 0.18 2.33 0.23
51 INT332258 Positive_regulation of Localization of Fgf1 1 0.18 2.32 0.23
52 INT245856 Regulation of Transcription of Fgf1 1 0.21 0.51 0.21
53 INT245863 Positive_regulation of Transcription of Fgf1 1 0.22 0.51 0.21
54 INT64189 Protein_catabolism of POR 1 0.37 0.16 0.18
55 INT280689 Regulation of Srebf1 1 0.29 0.42 0.17
56 INT239307 Positive_regulation of Abcg1 1 0.24 0.73 0.17
57 INT191584 Protein_catabolism of Fdps 1 0.12 1.92 0.16
58 INT101388 Regulation of Fdps 4 0.38 0.97 0.15
59 INT205562 Positive_regulation of Localization of Fgf1 1 0.50 0.25 0.13
60 INT203955 Binding of Srebf1 6 0.31 1.85 0.12
61 INT193777 Negative_regulation of Fgf1 6 0.13 4.26 0.12
62 INT115825 Positive_regulation of Gene_expression of Por 2 0.22 0.47 0.12
63 INT106015 Negative_regulation of Regulation of Fgf1 1 0.41 0.15 0.12
64 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11
65 INT187880 Binding of Abcg1 3 0.33 2.07 0.1
66 INT115833 Negative_regulation of Transcription of Por 1 0.20 0.52 0.09
67 INT205563 Regulation of Gene_expression of Fgf1 1 0.27 0.06 0.09
68 INT115828 Negative_regulation of Gene_expression of Por 1 0.20 0.52 0.09
69 INT262065 Negative_regulation of Gene_expression of Srebf1 4 0.49 1.78 0.08
70 INT65031 Negative_regulation of Gene_expression of Fgf1 3 0.43 0.25 0.08
71 INT229152 Negative_regulation of Abcg1 2 0.19 1.35 0.08
72 INT266341 Regulation of Localization of Fgf1 1 0.03 0.92 0.08
73 INT67606 Localization of POR 3 0.68 1.22 0.06
74 INT203953 Localization of Srebf1 3 0.62 1.15 0.05
75 INT205607 Regulation of Fgf1 4 0.24 3.34 0.04
76 INT290787 Phosphorylation of Srebf1 2 0.43 0.43 0.04
77 INT290776 Positive_regulation of Phosphorylation of Srebf1 1 0.26 0.08 0.04
78 INT280684 Transcription of Srebf1 11 0.50 2.38 0.03
79 INT176216 Negative_regulation of Srebf1 3 0.26 2.01 0.03
80 INT176206 Transcription of Srebf1 3 0.14 0.37 0.03
81 INT239270 Transcription of Abcg1 1 0.27 1.21 0.03
82 INT280683 Gene_expression of Srebf1 12 0.44 6.31 0
83 INT280659 Negative_regulation of Srebf1 4 0.32 1.83 0
84 INT280643 Negative_regulation of Gene_expression of Srebf1 4 0.32 1.01 0
85 INT280638 Positive_regulation of Transcription of Srebf1 4 0.37 1.18 0
86 INT260288 Binding of FGF1 3 0.32 2.46 0
87 INT280673 Positive_regulation of Srebf1 3 0.37 0.96 0
88 INT280636 Negative_regulation of Transcription of Srebf1 3 0.31 0.71 0
89 INT198867 Protein_catabolism of Srebf1 2 0.08 1.2 0
90 INT280649 Positive_regulation of Positive_regulation of Srebf1 2 0.37 0.64 0
91 INT265570 Binding of Fgf1 2 0.10 0.91 0
92 INT280662 Negative_regulation of Positive_regulation of Srebf1 2 0.31 0.65 0
93 INT345450 Binding of Srebf1 1 0.03 0 0
94 INT181822 Negative_regulation of Negative_regulation of Srebf1 1 0.10 0.09 0
95 INT323616 Phosphorylation of POR 1 0.05 0.7 0
96 INT323617 Positive_regulation of Phosphorylation of POR 1 0.03 0.7 0
97 INT262069 Positive_regulation of Transcription of Srebf1 1 0.07 0.05 0
98 INT264980 Transcription of POR 1 0.38 0.73 0
99 INT203954 Regulation of Localization of Srebf1 1 0.01 0.3 0
100 INT203956 Positive_regulation of Protein_catabolism of Srebf1 1 0.03 0.96 0
101 INT304206 Positive_regulation of Gene_expression of Srebf1 1 0.34 0.61 0
102 INT280640 Regulation of Transcription of Srebf1 1 0.21 0.09 0
103 INT343817 Transcription of Fdps 1 0.32 0 0
104 INT262072 Negative_regulation of Transcription of Srebf1 1 0.06 0.05 0
105 INT343816 Regulation of Gene_expression of Fdps 1 0.21 0.43 0
106 INT311652 Negative_regulation of Regulation of Fgf1 1 0.13 0.32 0
107 INT280669 Localization of Srebf1 1 0.35 0.09 0
108 INT191529 Negative_regulation of Positive_regulation of POR 1 0.02 1.5 0
109 INT238857 Phosphorylation of PRKAA1 1 0.01 1.73 0
110 INT280687 Protein_catabolism of Srebf1 1 0.41 0 0
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