GO:0045545

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Name syndecan binding
Categary Function
Go Slim No
Go Link GO:0045545
Unique Molecular Interactions 101
Total Molecular Interactions 132
Total Single Events 1629
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for syndecan binding. They are ordered first by their pain relevance and then by number of times they were reported for syndecan binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
2 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
3 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
4 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
5 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
6 INT351245 Binding of TNC and OPN1LW 1 0.03 0.89 1.31
7 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96
8 INT347391 Positive_regulation of RYBP Positive_regulation of Sdcbp 1 0.00 0.22 0.79
9 INT347398 RYBP Positive_regulation of Positive_regulation of Sdcbp 1 0.00 0.22 0.79
10 INT27526 Binding of Sdcbp and Eda 1 0.13 0 0.65
11 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64
12 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
13 INT352459 Gse1 Regulation of Gene_expression of Tnc 1 0.05 0 0.6
14 INT356351 Binding of CALM1 and TNC 1 0.02 0 0.52
15 INT148818 IL1B Regulation of Gene_expression of TNC 1 0.29 0.57 0.47
16 INT133745 Vcan Regulation of TNC 1 0.11 0.71 0.46
17 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46
18 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45
19 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
20 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
21 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
22 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
23 INT352452 Calca Regulation of Gene_expression of Tnc 1 0.04 0 0.28
24 INT352448 Gse1 Regulation of Tnc 1 0.03 0 0.28
25 INT352458 Dusp1 Regulation of Gene_expression of Tnc 1 0.07 0 0.28
26 INT245640 Nr3c2 Regulation of Positive_regulation of Hpse 1 0.08 0.66 0.26
27 INT299156 Smcp Negative_regulation of Tnc 1 0.05 0.7 0.22
28 INT319555 gr Positive_regulation of Positive_regulation of Hpse 1 0.09 0.11 0.22
29 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19
30 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18
31 INT222414 Tlr4 Positive_regulation of Hpse 1 0.00 0.61 0.18
32 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17
33 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
34 INT245641 Nr3c2 Regulation of Gene_expression of Hpse 1 0.14 2.67 0.17
35 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17
36 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
37 INT222420 Tlr4 Positive_regulation of Positive_regulation of Hpse 1 0.00 0.67 0.15
38 INT222551 Il6 Positive_regulation of Positive_regulation of Hpse 1 0.01 0.5 0.13
39 INT252571 Rpe Positive_regulation of Positive_regulation of Sdcbp 1 0.04 2.27 0.13
40 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13
41 INT311191 ecs Negative_regulation of HPSE 1 0.00 0.94 0.12
42 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
43 INT341879 Oxt Negative_regulation of Positive_regulation of Hpse 1 0.01 0.83 0.11
44 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11
45 INT303084 Binding of Mafk and Sdcbp 1 0.04 0.37 0.1
46 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1
47 INT252572 Rpe Positive_regulation of Sdcbp 1 0.04 1.12 0.09
48 INT341826 Binding of ERBB2 and TNC 1 0.18 0.63 0.09
49 INT313741 Negative_regulation of NOS1 Positive_regulation of Sdcbp 1 0.00 0.78 0.09
50 INT341825 Binding of TNC and PGR 1 0.14 0.63 0.09
51 INT186540 Binding of Cort and Hpse 1 0.05 0.92 0.08
52 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
53 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08
54 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
55 INT159463 Ptprn2 Negative_regulation of HPSE 1 0.00 0 0.07
56 INT330487 Binding of MME and HPSE 1 0.35 0 0.06
57 INT303059 Binding of Syt1 and Sdcbp 1 0.04 0.19 0.05
58 INT200428 Sdcbp Positive_regulation of Gene_expression of Gfap 1 0.04 0.15 0.04
59 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
60 INT185733 Hpse Positive_regulation of Gene_expression of Tnfrsf11b 1 0.20 0.24 0
61 INT317602 Binding of TNC and PAH 1 0.02 1.74 0
62 INT317843 Binding of TNC and TPSAB1 1 0.01 0.64 0
63 INT96043 Rasgrp1 Negative_regulation of Sdcbp 1 0.02 0.06 0
64 INT107179 asa Negative_regulation of Negative_regulation of Sdcbp 1 0.00 0.14 0
65 INT162510 Binding of ITPR1 and HPSE 1 0.02 0.05 0
66 INT317597 Binding of Gnrh1 and Hpse 1 0.08 0 0
67 INT79162 Binding of TNC and PLG 1 0.28 0.23 0
68 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0
69 INT222537 Binding of Nmu and Hpse 1 0.01 0.15 0
70 INT80910 Binding of TNC and TNNI3 1 0.21 0.07 0
71 INT80909 Binding of TNC and TNNC1 1 0.12 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for syndecan binding. They are ordered first by their pain relevance and then by number of times they were reported in syndecan binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
2 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11
3 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
4 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96
5 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16
6 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
7 INT46695 Positive_regulation of TNC 28 0.67 17.06 12.04
8 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03
9 INT79166 Regulation of TNC 12 0.44 9.42 8.13
10 INT79168 Binding of TNC 39 0.47 16.51 7.55
11 INT35712 Regulation of Sdcbp 19 0.23 5.3 6.58
12 INT37745 Positive_regulation of Gene_expression of Sdcbp 22 0.60 5.15 6.02
13 INT4938 Localization of Tnc 5 0.65 1.73 5.64
14 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17
15 INT79194 Positive_regulation of Tnc 5 0.41 2.25 4.69
16 INT14831 Negative_regulation of TNC 18 0.50 8.71 4.61
17 INT68369 Transcription of TNC 13 0.72 8.69 4.42
18 INT35122 Negative_regulation of Sdcbp 43 0.51 22.01 4.34
19 INT32053 Positive_regulation of Gene_expression of Tnc 5 0.45 3.4 4.13
20 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09
21 INT68978 Regulation of Positive_regulation of Hpse 6 0.45 1.88 4.02
22 INT44789 Binding of Sdcbp 10 0.36 1.65 4.01
23 INT61734 Regulation of HPSE 16 0.60 13.05 3.5
24 INT13321 Negative_regulation of Hpse 11 0.56 4.64 3.39
25 INT151421 Negative_regulation of Positive_regulation of Sdcbp 11 0.30 6.61 3.32
26 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91
27 INT69621 Positive_regulation of Positive_regulation of Hpse 7 0.42 4.1 2.85
28 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73
29 INT13414 Regulation of Regulation of Hpse 4 0.16 1.71 2.55
30 INT175797 Regulation of Gene_expression of Hpse 6 0.07 6.52 2.49
31 INT4939 Negative_regulation of Tnc 2 0.32 0.79 2.46
32 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
33 INT195080 Positive_regulation of Tnc 4 0.45 26.67 2.34
34 INT64700 Binding of Nf1 14 0.45 15.24 2.29
35 INT128210 Positive_regulation of Positive_regulation of Sdcbp 6 0.08 3.88 2.08
36 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
37 INT161432 Negative_regulation of Gene_expression of Tnc 2 0.38 1.44 1.93
38 INT68181 Binding of Nf1 6 0.48 8.14 1.88
39 INT35121 Negative_regulation of Gene_expression of Sdcbp 6 0.43 2.4 1.83
40 INT105148 Positive_regulation of Gene_expression of TNC 6 0.50 6.45 1.8
41 INT74707 Negative_regulation of Hpse 4 0.58 2.29 1.73
42 INT33591 Negative_regulation of Positive_regulation of Hpse 6 0.32 3.42 1.63
43 INT129492 Gene_expression of Hpse 11 0.75 6.56 1.59
44 INT74955 Negative_regulation of HPSE 6 0.57 4.75 1.57
45 INT159091 Positive_regulation of Regulation of Sdcbp 1 0.40 0.16 1.5
46 INT240359 Binding of Tnc 2 0.35 11.67 1.48
47 INT79167 Localization of TNC 8 0.78 4.15 1.44
48 INT351254 Regulation of Regulation of TNC 1 0.14 0.55 1.4
49 INT65553 Regulation of Hpse 6 0.27 3.89 1.37
50 INT45233 Positive_regulation of Binding of Sdcbp 1 0.07 0 1.36
51 INT154026 Negative_regulation of Regulation of Sdcbp 1 0.37 0 1.35
52 INT148638 Protein_catabolism of Hpse 1 0.48 1.09 1.28
53 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
54 INT175794 Negative_regulation of Gene_expression of Hpse 2 0.12 1.82 1.08
55 INT96229 Localization of HPSE 3 0.20 2.76 1.05
56 INT44787 Negative_regulation of Binding of Sdcbp 3 0.43 0.73 1.01
57 INT37746 Regulation of Gene_expression of Sdcbp 4 0.53 0.9 0.99
58 INT299153 Negative_regulation of Tnc 2 0.42 8.14 0.98
59 INT55580 Localization of Hpse 5 0.23 3.51 0.89
60 INT20624 Regulation of Gene_expression of TNC 5 0.60 2.49 0.87
61 INT109854 Negative_regulation of Positive_regulation of Hpse 1 0.23 0 0.81
62 INT65552 Binding of Hpse 2 0.30 2.48 0.8
63 INT124873 Positive_regulation of Positive_regulation of Tnc 1 0.35 0.14 0.75
64 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
65 INT179133 Localization of Nf1 2 0.80 2.18 0.68
66 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
67 INT129195 Transcription of Sdcbp 3 0.10 1.94 0.67
68 INT96339 Protein_catabolism of HPSE 5 0.96 2.87 0.63
69 INT317596 Positive_regulation of Gene_expression of Hpse 3 0.14 2.24 0.6
70 INT129493 Protein_catabolism of Hpse 2 0.55 2.81 0.57
71 INT354785 Regulation of Binding of Tnc 1 0.06 1.63 0.53
72 INT177436 Binding of HPSE 2 0.47 1.81 0.52
73 INT90353 Regulation of Gene_expression of Tnc 1 0.26 0.22 0.52
74 INT124872 Regulation of Localization of Tnc 1 0.31 0.1 0.52
75 INT225665 Positive_regulation of Binding of TNC 1 0.38 0.74 0.49
76 INT200421 Localization of Sdcbp 5 0.22 0.72 0.48
77 INT190590 Localization of Hpse 2 0.28 0.49 0.48
78 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
79 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
80 INT177437 Transcription of HPSE 2 0.23 3.44 0.41
81 INT84900 Positive_regulation of Localization of Hpse 1 0.16 0.16 0.41
82 INT319548 Positive_regulation of Localization of Hpse 1 0.17 0.08 0.38
83 INT22786 Regulation of Tnc 1 0.23 0.18 0.37
84 INT129494 Regulation of Gene_expression of Hpse 2 0.23 1.36 0.36
85 INT129495 Negative_regulation of Gene_expression of Hpse 1 0.36 0.52 0.36
86 INT74954 Positive_regulation of Positive_regulation of HPSE 2 0.40 0.45 0.34
87 INT55582 Positive_regulation of Negative_regulation of Hpse 2 0.13 0.56 0.32
88 INT177439 Negative_regulation of Positive_regulation of HPSE 1 0.21 1.48 0.32
89 INT78193 Regulation of Tnc 2 0.19 0.31 0.31
90 INT354784 Positive_regulation of Positive_regulation of Tnc 1 0.07 1.14 0.3
91 INT222720 Negative_regulation of Localization of Sdcbp 1 0.07 0.72 0.29
92 INT175796 Binding of Hpse 6 0.35 2.19 0.28
93 INT62984 Positive_regulation of Negative_regulation of Sdcbp 2 0.40 0.88 0.25
94 INT96337 Positive_regulation of Gene_expression of HPSE 1 0.67 2.28 0.25
95 INT129342 Positive_regulation of Positive_regulation of Nf1 1 0.50 0.79 0.23
96 INT68180 Regulation of Nf1 2 0.27 2.02 0.22
97 INT129341 Negative_regulation of Gene_expression of Nf1 2 0.43 1.67 0.2
98 INT155285 Positive_regulation of Nf1 1 0.16 0.55 0.17
99 INT178199 Localization of Tnc 2 0.78 5.29 0.16
100 INT103196 Negative_regulation of Gene_expression of Nf1 1 0.57 1.21 0.16
101 INT145276 Transcription of Hpse 1 0.53 0.65 0.14
102 INT145275 Regulation of Transcription of Hpse 1 0.27 0.65 0.14
103 INT190026 Positive_regulation of Gene_expression of Nf1 3 0.53 2.45 0.07
104 INT74953 Positive_regulation of Regulation of HPSE 2 0.49 1.02 0.07
105 INT118191 Regulation of Regulation of HPSE 2 0.26 0.87 0.07
106 INT148819 Positive_regulation of Positive_regulation of TNC 4 0.45 0.53 0.05
107 INT347453 Negative_regulation of Regulation of Hpse 1 0.12 0.3 0.04
108 INT349102 Positive_regulation of Gene_expression of Hpse 1 0.03 0.21 0.03
109 INT293138 Regulation of Negative_regulation of Sdcbp 1 0.04 0.11 0
110 INT296566 Regulation of Binding of Hpse 1 0.02 0.84 0
111 INT181695 Positive_regulation of Transcription of Sdcbp 1 0.04 1.1 0
112 INT210949 Positive_regulation of Negative_regulation of TNC 1 0.21 0.66 0
113 INT347383 Protein_catabolism of Sdcbp 1 0.04 0 0
114 INT308786 Negative_regulation of Gene_expression of TNC 1 0.02 0.08 0
115 INT335965 Negative_regulation of Localization of HPSE 1 0.11 0.93 0
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