GO:0045581

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Name negative regulation of T cell differentiation
Categary Process
Go Slim No
Go Link GO:0045581
Unique Molecular Interactions 53
Total Molecular Interactions 69
Total Single Events 436
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
2 INT165183 Ifnb1 Positive_regulation of P2rx4 1 0.04 1.73 1.73
3 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
4 INT129920 IFNA2 Regulation of ADO 1 0.00 0.64 0.64
5 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
6 INT346205 Binding of CD74 and TPPP 1 0.02 0.87 0.51
7 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46
8 INT140574 Ifnb1 Positive_regulation of Il6 1 0.05 0.9 0.39
9 INT140571 Ifng Positive_regulation of Ifnb1 1 0.01 0.82 0.36
10 INT140575 Il6 Positive_regulation of Ifnb1 1 0.02 0.82 0.36
11 INT140572 Ifng Positive_regulation of Gene_expression of Ifnb1 1 0.01 0.82 0.36
12 INT140573 Positive_regulation of Ifng Positive_regulation of Ifnb1 1 0.01 0.83 0.36
13 INT174459 IL8 Positive_regulation of Gene_expression of Cd74 1 0.00 0.61 0.35
14 INT41787 IFNA2 Negative_regulation of Glb1 1 0.04 0.09 0.23
15 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
16 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
17 INT43495 Cd74 Regulation of Gene_expression of Ifng 1 0.47 0 0.14
18 INT298052 Binding of Cd74 and Vip 1 0.00 1.05 0.13
19 INT87839 Binding of Cd74 and Dcn 1 0.36 0.21 0.13
20 INT254488 Dtx1 Regulation of Sorbs1 1 0.01 0 0.12
21 INT254490 Dtx1 Regulation of Gopc 1 0.04 0 0.12
22 INT254492 Dtx1 Regulation of Cldn11 1 0.03 0 0.09
23 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
24 INT49609 IFNA2 Positive_regulation of Alpk1 1 0.00 0.73 0.07
25 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
26 INT353284 Prdx2 Negative_regulation of Gene_expression of Smad2 1 0.16 0.07 0.05
27 INT60089 IL2 Regulation of IFNA2 1 0.25 0.09 0.05
28 INT339979 Binding of PRDX2 and HDAC9 1 0.02 0.16 0.05
29 INT268677 IFNA2 Positive_regulation of XRCC1 1 0.05 0.75 0.05
30 INT143993 Prdx2 Positive_regulation of Atp13a4 1 0.00 0 0.05
31 INT353289 Prdx2 Negative_regulation of Positive_regulation of Smad2 1 0.18 0.17 0.04
32 INT348820 Cd74 Regulation of Gene_expression of TFDP3 1 0.07 0.16 0.04
33 INT353293 Prdx2 Negative_regulation of Localization of Smad2 1 0.16 0 0.04
34 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
35 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
36 INT353286 Prdx2 Positive_regulation of Phosphorylation of Smad2 1 0.24 0.06 0.03
37 INT60088 IFNA2 Positive_regulation of IL2 1 0.12 0.07 0.03
38 INT353283 Prdx2 Positive_regulation of Phosphorylation of Tgif1 1 0.10 0.06 0.03
39 INT353292 Prdx2 Positive_regulation of Tgif1 1 0.10 0.06 0.03
40 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0
41 INT210707 Binding of IFNA2 and IL2 1 0.06 0.91 0
42 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0
43 INT268809 Binding of IFNA2 and PAEP 1 0.01 0.16 0
44 INT20010 Binding of Ifnb1 and Ifng 1 0.01 0 0
45 INT103769 AMY2A Positive_regulation of IFNA2 1 0.01 0.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68
2 INT5871 Binding of IFNA2 38 0.48 20.35 6.46
3 INT5297 Regulation of IFNA2 20 0.56 10.81 5.13
4 INT5870 Negative_regulation of IFNA2 20 0.49 12 4.3
5 INT253970 Positive_regulation of Cd74 3 0.48 8.16 4.09
6 INT187168 Binding of Cd74 13 0.27 11.2 3.44
7 INT167039 Gene_expression of Cd74 24 0.40 17.12 2.84
8 INT243350 Binding of CD74 2 0.11 4.86 2.72
9 INT11235 Positive_regulation of IFNA2 27 0.69 15.32 2.57
10 INT64982 Positive_regulation of Ifnb1 10 0.48 6.16 2.35
11 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08
12 INT253975 Binding of Cd74 4 0.27 4.57 1.88
13 INT109010 Negative_regulation of Ifnb1 1 0.12 2.47 1.56
14 INT22075 Positive_regulation of Gene_expression of IFNA2 7 0.64 4.7 1.45
15 INT271443 Regulation of Cd74 1 0.33 2.73 1.4
16 INT23986 Positive_regulation of Ifnb1 4 0.42 0.62 1.39
17 INT14335 Gene_expression of Ifnb1 5 0.40 2.7 1.38
18 INT108249 Negative_regulation of Prdx2 3 0.32 1.85 1.36
19 INT40189 Localization of IFNA2 6 0.74 7.7 1.04
20 INT108243 Positive_regulation of Prdx2 3 0.34 0.85 0.95
21 INT116058 Gene_expression of Cd74 2 0.56 0.55 0.89
22 INT126566 Binding of Ifnb1 3 0.31 2.43 0.85
23 INT174420 Positive_regulation of Gene_expression of Cd74 3 0.20 1.92 0.81
24 INT136147 Regulation of Ifnb1 2 0.44 1.75 0.72
25 INT40190 Positive_regulation of Regulation of IFNA2 1 0.49 0.07 0.68
26 INT193672 Gene_expression of Prdx2 3 0.50 2.75 0.64
27 INT29259 Gene_expression of Ifnb1 4 0.65 1.32 0.62
28 INT116060 Negative_regulation of Gene_expression of Cd74 1 0.12 0 0.61
29 INT271439 Positive_regulation of Localization of Cd74 1 0.36 1.01 0.52
30 INT29258 Positive_regulation of Gene_expression of Ifnb1 2 0.42 2.16 0.51
31 INT271435 Localization of Cd74 1 0.54 0.95 0.49
32 INT174418 Regulation of Gene_expression of Cd74 1 0.04 0.9 0.46
33 INT123720 Negative_regulation of Positive_regulation of Ifnb1 1 0.34 0.26 0.45
34 INT76021 Negative_regulation of Positive_regulation of Ifnb1 1 0.40 0.19 0.44
35 INT254172 Negative_regulation of Gene_expression of Cd74 1 0.24 1.03 0.44
36 INT71024 Negative_regulation of Gene_expression of IFNA2 1 0.53 0.08 0.42
37 INT140576 Positive_regulation of Regulation of Ifnb1 1 0.30 0.9 0.39
38 INT62874 Gene_expression of CD74 1 0.00 0.64 0.37
39 INT22074 Negative_regulation of Regulation of IFNA2 1 0.39 1.16 0.36
40 INT140577 Positive_regulation of Gene_expression of Ifnb1 1 0.30 0.81 0.36
41 INT51504 Negative_regulation of Gene_expression of Ifnb1 1 0.01 0.49 0.25
42 INT143991 Gene_expression of Prdx2 5 0.61 1.54 0.22
43 INT250818 Positive_regulation of Localization of IFNA2 4 0.12 5.06 0.2
44 INT161959 Gene_expression of PRDX2 2 0.65 1.38 0.2
45 INT353278 Binding of Prdx2 1 0.21 0.05 0.18
46 INT353270 Regulation of Binding of Prdx2 1 0.25 0.05 0.18
47 INT353274 Transcription of Prdx2 1 0.39 0.51 0.16
48 INT254481 Regulation of Dtx1 1 0.04 0 0.16
49 INT287133 Negative_regulation of Binding of Ifnb1 1 0.11 0.31 0.15
50 INT353264 Negative_regulation of Negative_regulation of Prdx2 1 0.24 0.45 0.15
51 INT131015 Negative_regulation of Cd74 1 0.17 0.25 0.12
52 INT193676 Positive_regulation of Gene_expression of Prdx2 2 0.06 1.31 0.09
53 INT19108 Positive_regulation of Negative_regulation of IFNA2 2 0.49 1.7 0.08
54 INT52199 Regulation of Gene_expression of IFNA2 2 0.06 1.69 0.07
55 INT243508 Negative_regulation of Dtx1 1 0.01 0.55 0.06
56 INT324127 Positive_regulation of Cd74 2 0.07 1.34 0.04
57 INT340756 Positive_regulation of PRDX2 1 0.02 1.23 0.04
58 INT143990 Regulation of Prdx2 1 0.22 0 0.03
59 INT206742 Negative_regulation of PRDX2 5 0.04 5.04 0
60 INT100350 Protein_catabolism of IFNA2 2 0.44 0.46 0
61 INT194148 Positive_regulation of CD74 2 0.27 0.68 0
62 INT324126 Negative_regulation of Binding of Cd74 1 0.08 0.31 0
63 INT268826 Regulation of Localization of IFNA2 1 0.07 0.43 0
64 INT339996 Positive_regulation of Negative_regulation of PRDX2 1 0.05 1.27 0
65 INT324125 Positive_regulation of Binding of Cd74 1 0.09 0.62 0
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