GO:0045590

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Name negative regulation of regulatory T cell differentiation
Categary Process
Go Slim No
Go Link GO:0045590
Unique Molecular Interactions 34
Total Molecular Interactions 104
Total Single Events 207
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of regulatory T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of regulatory T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
3 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
4 INT165200 Binding of CTLA4 and Crp 1 0.09 1.64 1.91
5 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
6 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
7 INT139069 Binding of CTLA4 and Cd86 3 0.16 0.65 0.7
8 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
9 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
10 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
11 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
12 INT157657 Binding of CTLA4 and FCGR1A 1 0.01 0.07 0.4
13 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
14 INT139068 Binding of CTLA4 and Cd80 1 0.00 0.33 0.33
15 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32
16 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32
17 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28
18 INT333549 Binding of CTLA4 and PDCD1 1 0.36 1.2 0.27
19 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22
20 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18
21 INT252367 Binding of RUNX1 and CTLA4 1 0.02 0.48 0.18
22 INT172824 Positive_regulation of Binding of Tnfsf4 and T2dm2 1 0.00 2.97 0.12
23 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
24 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09
25 INT145987 Binding of CTLA4 and Aip 1 0.08 0.61 0.09
26 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08
27 INT248945 Ctla4 Regulation of Gene_expression of Cd4 1 0.18 0 0.04
28 INT299450 Foxl2 Regulation of Ctla4 1 0.24 0.35 0.03
29 INT299442 Foxl2 Regulation of Transcription of Ctla4 1 0.24 0.35 0.03
30 INT265217 Negative_regulation of Binding of Ctla4 and Cd86 1 0.15 0.14 0
31 INT172831 Binding of INS and Tnfsf4 1 0.02 1.07 0
32 INT265223 Negative_regulation of Binding of Ctla4 and Cd28 1 0.18 0.14 0
33 INT149120 Binding of CTLA4 and Cd28 1 0.03 0.14 0
34 INT227773 Ctla4 Negative_regulation of Binding of Cd80 1 0.01 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of regulatory T cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of regulatory T cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07
2 INT132278 Binding of CTLA4 32 0.39 18.69 8.17
3 INT157401 Gene_expression of Ctla4 21 0.65 15.43 3.2
4 INT67796 Negative_regulation of CTLA4 13 0.39 8.36 2.39
5 INT143083 Regulation of CTLA4 4 0.25 1.06 1.36
6 INT145986 Positive_regulation of CTLA4 8 0.56 2.66 0.82
7 INT94743 Regulation of Ctla4 1 0.44 1.28 0.8
8 INT157491 Negative_regulation of Ctla4 5 0.31 2.68 0.63
9 INT228476 Binding of Ctla4 4 0.36 3.03 0.62
10 INT174797 Regulation of Tnfsf4 1 0.03 4.05 0.54
11 INT264192 Positive_regulation of Gene_expression of CTLA4 6 0.43 2.06 0.45
12 INT172800 Binding of Tnfsf4 2 0.04 4.58 0.45
13 INT172801 Positive_regulation of Tnfsf4 4 0.08 7.95 0.44
14 INT160874 Protein_catabolism of CTLA4 1 0.88 0.56 0.39
15 INT294135 Positive_regulation of Positive_regulation of CTLA4 1 0.25 0.45 0.32
16 INT174805 Gene_expression of Tnfsf4 1 0.04 3.49 0.28
17 INT173956 Negative_regulation of Gene_expression of CTLA4 3 0.37 0.91 0.2
18 INT296068 Regulation of Gene_expression of CTLA4 1 0.16 0.22 0.2
19 INT277827 Localization of CTLA4 1 0.65 0 0.18
20 INT277819 Positive_regulation of Localization of CTLA4 1 0.43 0 0.18
21 INT229557 Positive_regulation of Ctla4 5 0.43 3.83 0.17
22 INT299419 Transcription of Ctla4 2 0.43 0.71 0.17
23 INT264177 Positive_regulation of Gene_expression of Ctla4 2 0.49 3.59 0.17
24 INT311833 Localization of Ctla4 1 0.17 0.26 0.14
25 INT172790 Negative_regulation of Tnfsf4 1 0.05 2.43 0.14
26 INT172785 Positive_regulation of Binding of Tnfsf4 1 0.05 2.89 0.12
27 INT149118 Regulation of Binding of CTLA4 1 0.33 0.32 0.07
28 INT276341 Transcription of CTLA4 1 0.30 1.04 0.07
29 INT174802 Positive_regulation of Regulation of Tnfsf4 1 0.03 0.92 0.06
30 INT283499 Negative_regulation of Positive_regulation of CTLA4 1 0.09 1.02 0.05
31 INT174799 Regulation of Binding of Tnfsf4 1 0.03 0.92 0.04
32 INT229560 Positive_regulation of Positive_regulation of Ctla4 1 0.28 0.53 0.04
33 INT229558 Negative_regulation of Negative_regulation of Ctla4 1 0.26 0.48 0.03
34 INT283512 Positive_regulation of Binding of CTLA4 1 0.11 1.03 0.03
35 INT264176 Positive_regulation of Binding of Ctla4 1 0.49 0.22 0
36 INT174153 Negative_regulation of Gene_expression of Ctla4 1 0.12 0.8 0
37 INT174152 Positive_regulation of Negative_regulation of Ctla4 1 0.14 0.8 0
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