GO:0045595

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Name regulation of cell differentiation
Categary Process
Go Slim No
Go Link GO:0045595
Unique Molecular Interactions 371
Total Molecular Interactions 502
Total Single Events 2565
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
2 INT88449 Uncx Positive_regulation of Penk 1 0.12 0 1.27
3 INT88446 Uncx Positive_regulation of Th 1 0.13 0 1.1
4 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
5 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
6 INT8415 LIF Regulation of VIP 1 0.13 0.36 1.04
7 INT56743 LIF Positive_regulation of Cck 1 0.08 0.18 1.02
8 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
9 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
10 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
11 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
12 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
13 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
14 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
15 INT149597 Lif Regulation of Regulation of Gal 1 0.30 0.69 0.73
16 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
17 INT149596 Lif Negative_regulation of Negative_regulation of Gal 1 0.10 0.5 0.7
18 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
19 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
20 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
21 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
22 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
23 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
24 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
25 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
26 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
27 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
28 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
29 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63
30 INT82267 Lif Regulation of Gene_expression of Gal 1 0.40 2.76 0.62
31 INT149595 Lif Negative_regulation of Negative_regulation of Trpv1 1 0.34 0.44 0.61
32 INT323148 PRKCA Positive_regulation of RAF1 1 0.01 0 0.55
33 INT323150 PRKCA Positive_regulation of Phosphorylation of RAF1 1 0.01 0 0.55
34 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
35 INT8440 Cntf Regulation of LIF 1 0.33 0.18 0.52
36 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
37 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
38 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
39 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
40 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
41 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
42 INT98480 Lif Positive_regulation of Pnoc 1 0.18 0.2 0.49
43 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
44 INT184105 Il6 Positive_regulation of Socs3 2 0.42 1.34 0.48
45 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48
46 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
47 INT98484 Lif Regulation of Gene_expression of Gal 1 0.04 0.16 0.47
48 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
49 INT98482 Lif Positive_regulation of Gene_expression of Pnoc 1 0.16 0.17 0.46
50 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46
51 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45
52 INT98481 Lif Regulation of Regulation of Oprl1 1 0.04 0.16 0.45
53 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43
54 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43
55 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
56 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 0.12 0 0.4
57 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39
58 INT124798 RAF1 Regulation of PRKCA 1 0.06 0 0.39
59 INT216737 Binding of ADORA2B and TCFL5 1 0.03 0.05 0.39
60 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39
61 INT319905 Binding of PCAP and TCFL5 1 0.19 0 0.38
62 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38
63 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
64 INT216738 Binding of ATP6V0A1 and TCFL5 1 0.01 0.06 0.38
65 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
66 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
67 INT184128 Socs3 Negative_regulation of Il6 1 0.12 1.14 0.36
68 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
69 INT72180 Binding of CTRC and Cela1 1 0.00 0.65 0.34
70 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
71 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34
72 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
73 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
74 INT184082 Binding of Socs3 and Il6 1 0.11 0.49 0.33
75 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
76 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
77 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
78 INT56092 FGFR1 Positive_regulation of Transcription of SERPINE1 1 0.29 0.41 0.29
79 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
80 INT154044 Gm6983 Positive_regulation of Localization of FGFR1 1 0.00 0.06 0.28
81 INT26669 Nanog Regulation of Binding of Tlyr1 1 0.02 0 0.28
82 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
83 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
84 INT315200 Negative_regulation of Binding of Socs3 and Stat3 1 0.26 1.18 0.27
85 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26
86 INT118851 GNA14 Positive_regulation of RAF1 1 0.00 0.14 0.26
87 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25
88 INT70661 Binding of Hrasls and Nkx2-2 1 0.02 0 0.24
89 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
90 INT134523 Nrg1 Positive_regulation of Gene_expression of Mpz 1 0.49 0.32 0.23
91 INT88447 Uncx Negative_regulation of Binding of Jun 1 0.07 0 0.22
92 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22
93 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2
94 INT82268 Lif Regulation of Gene_expression of Iapp 1 0.06 0.9 0.2
95 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
96 INT336379 TIMP1 Negative_regulation of FADS1 1 0.01 0.52 0.2
97 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2
98 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18
99 INT125550 FGFR1 Negative_regulation of Cyp2e1 1 0.02 0.06 0.18
100 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18
101 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
102 INT88451 Uncx Regulation of Transcription of Penk 1 0.06 0 0.17
103 INT184103 Binding of Socs3 and Il11ra1 1 0.12 0 0.17
104 INT88450 Uncx Regulation of Gene_expression of Th 1 0.06 0 0.17
105 INT88445 Uncx Positive_regulation of Gene_expression of Penk 1 0.10 0 0.17
106 INT222426 Lif Positive_regulation of Localization of Pomc 1 0.02 0.75 0.17
107 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
108 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
109 INT32211 POMC Positive_regulation of Gene_expression of Lif 1 0.01 0.61 0.15
110 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15
111 INT123180 Bmp6 Positive_regulation of Lamtor1 1 0.01 0.61 0.14
112 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
113 INT250778 Binding of Socs3 and Atl1 1 0.01 0.6 0.14
114 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14
115 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
116 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
117 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
118 INT184104 Binding of Socs3 and Gopc 1 0.10 0 0.14
119 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
120 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
121 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
122 INT125551 Binding of FGFR1 and Cyp2e1 1 0.02 0.07 0.13
123 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
124 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
125 INT125549 Binding of CYP2B6 and FGFR1 1 0.00 0.07 0.13
126 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12
127 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12
128 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12
129 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
130 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
131 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11
132 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
133 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11
134 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
135 INT294440 KLK4 Negative_regulation of LIF 1 0.00 0 0.1
136 INT188357 Csf2 Positive_regulation of Socs3 1 0.36 0.15 0.1
137 INT231273 Binding of Egfr and Nrg1 1 0.12 0 0.09
138 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
139 INT341008 Nrg1 Regulation of Binding of Erbb4 1 0.04 0 0.09
140 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
141 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
142 INT117838 FGFR1 Regulation of FGF2 1 0.33 0.17 0.09
143 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
144 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
145 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
146 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
147 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08
148 INT191758 ROS1 Positive_regulation of TFAP2A 1 0.01 0.54 0.08
149 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
150 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08
151 INT299539 Lif Positive_regulation of Phosphorylation of Stat3 1 0.08 0 0.08
152 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08
153 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
154 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08
155 INT184119 Socs3 Negative_regulation of Csf3 1 0.21 0.64 0.08
156 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
157 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07
158 INT12987 LIF Regulation of Localization of Prl 1 0.09 0 0.07
159 INT299535 Binding of Egf and Lif 1 0.07 0 0.07
160 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
161 INT316492 Stat3 Positive_regulation of Socs3 1 0.46 0.19 0.06
162 INT238218 STAT3 Positive_regulation of Gene_expression of Socs3 1 0.14 0 0.05
163 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05
164 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05
165 INT184123 Socs3 Positive_regulation of Protein_catabolism of Insr 1 0.03 0.41 0.05
166 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05
167 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05
168 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
169 INT243783 FGFR1 Positive_regulation of FGF20 1 0.05 0 0.04
170 INT276949 Hspd1 Positive_regulation of Gene_expression of Socs3 1 0.15 0.71 0.04
171 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
172 INT268652 Binding of CLDN4 and LIF 1 0.35 0.44 0.04
173 INT261388 Nsdhl Regulation of Lif 1 0.08 0.67 0.04
174 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
175 INT276967 Hspd1 Regulation of Gene_expression of Socs3 1 0.14 0.71 0.04
176 INT341009 Nrg1 Positive_regulation of Gene_expression of Fabp7 1 0.10 0.49 0.04
177 INT282561 POU5F1 Positive_regulation of Gene_expression of NANOG 1 0.11 0.26 0.04
178 INT231276 Erbb4 Positive_regulation of Nrg1 2 0.35 0.06 0.03
179 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03
180 INT261377 Nsdhl Positive_regulation of Lif 1 0.08 0.6 0.03
181 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
182 INT267093 FGFR1 Positive_regulation of Gene_expression of P2rx1 1 0.03 0.2 0.03
183 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03
184 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03
185 INT266075 LIF Regulation of Gene_expression of PAEP 1 0.19 0.43 0.03
186 INT266070 LIF Regulation of Gene_expression of PAPPA 1 0.35 0.49 0.03
187 INT267092 FGFR1 Positive_regulation of Gene_expression of P2rx6 1 0.04 0.2 0.03
188 INT231275 Erbb4 Positive_regulation of Gene_expression of Nrg1 1 0.35 0 0.03
189 INT266072 LGALS1 Regulation of Gene_expression of LIF 1 0.17 0.43 0.03
190 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
191 INT267094 FGFR1 Negative_regulation of Gene_expression of P2rx6 1 0.04 0.21 0.03
192 INT266067 PAPPA Regulation of Gene_expression of LIF 1 0.35 0.49 0.03
193 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03
194 INT266076 LIF Regulation of Gene_expression of LGALS1 1 0.17 0.43 0.03
195 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
196 INT260268 Binding of FGF2 and FGFR1 1 0.46 0.94 0
197 INT66341 LIF Positive_regulation of Gene_expression of FOS 1 0.11 1.07 0
198 INT66339 LIF Positive_regulation of Phosphorylation of CLIP2 1 0.45 1.57 0
199 INT268651 NUPL2 Positive_regulation of Gene_expression of LIF 1 0.66 0.07 0
200 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34
2 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
3 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
4 INT142462 Positive_regulation of Gene_expression of Socs3 23 0.68 23.27 8.27
5 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
6 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56
7 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76
8 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36
9 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
10 INT42378 Positive_regulation of Socs3 21 0.67 15.81 5.71
11 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
12 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
13 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
14 INT97903 Negative_regulation of FGFR1 16 0.17 5.6 4.57
15 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
16 INT105171 Phosphorylation of RAF1 11 0.74 2.33 4.19
17 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
18 INT15771 Gene_expression of Nrg1 34 0.67 3.16 4.11
19 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
20 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
21 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
22 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7
23 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
24 INT82265 Gene_expression of Lif 7 0.50 6.17 3.4
25 INT119421 Negative_regulation of RAF1 10 0.41 6.94 3.31
26 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
27 INT76240 Positive_regulation of Lif 6 0.69 6.04 3.13
28 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
29 INT14485 Positive_regulation of Cela1 15 0.44 10.55 3.01
30 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
31 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
32 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
33 INT184005 Negative_regulation of Gene_expression of Socs3 6 0.48 8.76 2.74
34 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
35 INT142465 Negative_regulation of Socs3 8 0.48 8.31 2.62
36 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
37 INT142908 Localization of FGFR1 18 0.38 11.46 2.57
38 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
39 INT33895 Positive_regulation of LIF 9 0.67 2.47 2.34
40 INT114327 Positive_regulation of RAF1 26 0.51 20.87 2.32
41 INT15290 Gene_expression of Cela1 17 0.52 7.56 2.22
42 INT168983 Negative_regulation of Nrg1 11 0.43 3.4 2.03
43 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
44 INT199738 Binding of TCFL5 4 0.24 0.08 1.98
45 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
46 INT44027 Positive_regulation of Lif 7 0.40 2.76 1.9
47 INT62692 Localization of Nanog 3 0.73 0.82 1.85
48 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
49 INT41515 Negative_regulation of CELA1 3 0.51 2.37 1.73
50 INT3818 Regulation of Apc 13 0.39 12.52 1.68
51 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
52 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
53 INT15363 Gene_expression of CELA1 10 0.78 3.22 1.59
54 INT253751 Localization of Lif 3 0.73 3.94 1.58
55 INT38893 Localization of CELA1 6 0.70 2.36 1.57
56 INT50437 Regulation of LIF 6 0.44 2.12 1.53
57 INT105784 Binding of Nrg1 7 0.37 1.29 1.52
58 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
59 INT184032 Regulation of Socs3 6 0.37 4.08 1.48
60 INT112845 Negative_regulation of Binding of Nkx2-2 2 0.12 0.14 1.47
61 INT140245 Binding of Gli3 3 0.36 2.65 1.46
62 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
63 INT132081 Regulation of Gene_expression of Nkx2-2 2 0.10 0.24 1.43
64 INT50436 Negative_regulation of Positive_regulation of LIF 1 0.37 0.33 1.42
65 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
66 INT34933 Positive_regulation of Gene_expression of LIF 6 0.67 3.41 1.38
67 INT220177 Binding of Apc 21 0.37 15.34 1.37
68 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
69 INT158056 Localization of Nrg1 13 0.79 3.11 1.28
70 INT52212 Gene_expression of Bmp6 6 0.64 2.38 1.27
71 INT184056 Regulation of Gene_expression of Socs3 4 0.45 4.24 1.22
72 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
73 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
74 INT330526 Positive_regulation of Gene_expression of DICER1 5 0.30 3.34 1.18
75 INT127805 Positive_regulation of Phosphorylation of RAF1 3 0.45 1.21 1.17
76 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
77 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
78 INT184020 Localization of Socs3 3 0.75 4.05 1.06
79 INT101994 Positive_regulation of Nrg1 10 0.50 1.24 1.05
80 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
81 INT216760 Negative_regulation of Binding of TCFL5 2 0.27 0 1.04
82 INT74977 Binding of FGFR1 6 0.41 4.66 1.02
83 INT17715 Positive_regulation of CELA1 8 0.61 3.76 1
84 INT149594 Positive_regulation of Gene_expression of Lif 2 0.47 0.89 1
85 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
86 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
87 INT52213 Regulation of Localization of Bmp6 1 0.44 0.39 0.93
88 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
89 INT97899 Positive_regulation of Gene_expression of FGFR1 7 0.62 5.99 0.9
90 INT242134 Localization of Apc 8 0.74 4.83 0.88
91 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
92 INT52215 Localization of Bmp6 1 0.73 0.37 0.88
93 INT102819 Regulation of Lif 8 0.53 2.05 0.87
94 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
95 INT304863 Negative_regulation of Gene_expression of Nanog 4 0.41 0.91 0.84
96 INT98478 Negative_regulation of Lif 3 0.42 1.29 0.84
97 INT15362 Negative_regulation of Cela1 4 0.21 2.47 0.83
98 INT82262 Regulation of Lif 3 0.31 1.67 0.83
99 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
100 INT221543 Binding of Fes 1 0.45 1.79 0.83
101 INT354449 Positive_regulation of Localization of Lif 1 0.33 1.24 0.83
102 INT184026 Binding of Socs3 7 0.42 1.93 0.81
103 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
104 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
105 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
106 INT138396 Transcription of Nkx2-2 1 0.26 0.05 0.75
107 INT138395 Positive_regulation of Transcription of Nkx2-2 1 0.19 0.05 0.75
108 INT139846 Protein_catabolism of Nrg1 5 0.60 1.78 0.74
109 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
110 INT126736 Positive_regulation of Gene_expression of Nrg1 3 0.50 0.42 0.71
111 INT68794 Negative_regulation of LIF 6 0.41 1.38 0.7
112 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
113 INT99239 Negative_regulation of Negative_regulation of FGFR1 1 0.06 0.3 0.69
114 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
115 INT21983 Regulation of Cela1 4 0.18 2.9 0.67
116 INT54497 Binding of Nanog 1 0.35 0 0.67
117 INT2109 Negative_regulation of Gene_expression of LIF 4 0.41 0.89 0.66
118 INT35562 Regulation of CELA1 4 0.04 1.67 0.65
119 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
120 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
121 INT62732 Positive_regulation of Gene_expression of Nanog 2 0.45 0.27 0.63
122 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
123 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
124 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
125 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
126 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
127 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
128 INT97901 Regulation of FGFR1 5 0.24 2.56 0.55
129 INT97904 Negative_regulation of Gene_expression of FGFR1 1 0.38 0.92 0.55
130 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
131 INT184065 Phosphorylation of Socs3 2 0.81 2.67 0.53
132 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
133 INT135062 Transcription of Gli3 1 0.05 0 0.52
134 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
135 INT15770 Negative_regulation of Gene_expression of Nrg1 3 0.43 1.27 0.5
136 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
137 INT304861 Regulation of Gene_expression of Nanog 3 0.43 0.13 0.46
138 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
139 INT216834 Localization of Lif 2 0.34 0.23 0.46
140 INT299516 Phosphorylation of Lif 1 0.26 0.56 0.46
141 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
142 INT234580 Regulation of Positive_regulation of Socs3 1 0.26 0.54 0.46
143 INT52214 Regulation of Gene_expression of Bmp6 1 0.37 0.19 0.46
144 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
145 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
146 INT2110 Localization of LIF 5 0.73 1.59 0.44
147 INT267122 Negative_regulation of Positive_regulation of FGFR1 1 0.03 1.03 0.44
148 INT22728 Localization of Cela1 3 0.48 1.69 0.43
149 INT323167 Negative_regulation of Phosphorylation of RAF1 1 0.08 0 0.43
150 INT252737 Gene_expression of RAF1 12 0.58 10.97 0.42
151 INT88453 Gene_expression of Uncx 5 0.33 2.48 0.42
152 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
153 INT32207 Regulation of Gene_expression of Lif 3 0.19 1.01 0.42
154 INT48503 Positive_regulation of Positive_regulation of Nkx2-2 1 0.15 0 0.42
155 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
156 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
157 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
158 INT84326 Protein_catabolism of Nanog 1 0.02 0 0.41
159 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
160 INT15289 Positive_regulation of Gene_expression of Cela1 2 0.46 1.32 0.4
161 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
162 INT272502 Transcription of DICER1 3 0.08 2.14 0.39
163 INT343811 Positive_regulation of Transcription of DICER1 1 0.06 2.06 0.39
164 INT80302 Binding of TFAP2A 7 0.39 1.67 0.38
165 INT123185 Positive_regulation of Gene_expression of Bmp6 2 0.24 1.28 0.38
166 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
167 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
168 INT23704 Binding of Cela1 2 0.39 1.03 0.37
169 INT106402 Positive_regulation of TFAP2A 2 0.13 0.35 0.35
170 INT23705 Positive_regulation of Localization of Cela1 2 0.32 1.35 0.35
171 INT197147 Gene_expression of TCFL5 2 0.07 0 0.35
172 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
173 INT343810 Binding of DICER1 1 0.05 1.88 0.35
174 INT330525 Positive_regulation of DICER1 2 0.17 1.34 0.34
175 INT334851 Positive_regulation of Localization of Nrg1 1 0.30 0.68 0.34
176 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33
177 INT173635 Negative_regulation of TFAP2A 3 0.34 2.93 0.33
178 INT225667 Transcription of Apc 3 0.52 3.73 0.32
179 INT122619 Gene_expression of Nkx2-2 6 0.36 0.15 0.31
180 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
181 INT190451 Gene_expression of NANOG 33 0.59 3.28 0.29
182 INT299519 Binding of Lif 2 0.21 0.67 0.29
183 INT15361 Positive_regulation of Negative_regulation of Cela1 1 0.03 0.39 0.29
184 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
185 INT154043 Positive_regulation of Localization of FGFR1 1 0.02 0.06 0.28
186 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27
187 INT149893 Positive_regulation of Gene_expression of Ihh 1 0.69 0.62 0.26
188 INT208497 Localization of Nkx2-2 1 0.01 0 0.26
189 INT149892 Gene_expression of Ihh 1 0.77 0.61 0.26
190 INT135061 Protein_catabolism of Gli3 1 0.04 0 0.25
191 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
192 INT350691 Localization of DICER1 1 0.08 1.18 0.23
193 INT188235 Phosphorylation of LIF 1 0.53 0.48 0.23
194 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
195 INT134810 Binding of CELA1 1 0.12 1.02 0.22
196 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
197 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
198 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
199 INT252745 Positive_regulation of Positive_regulation of RAF1 3 0.20 4.62 0.21
200 INT251969 Negative_regulation of FADS1 2 0.43 0.52 0.2
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