GO:0045596

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Name negative regulation of cell differentiation
Categary Process
Go Slim No
Go Link GO:0045596
Unique Molecular Interactions 772
Total Molecular Interactions 1031
Total Single Events 7413
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
2 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
3 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
4 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
5 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
6 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
7 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
8 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
9 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
10 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
11 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
12 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
13 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
14 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
15 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
16 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
17 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
18 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15
19 INT167819 IFNA1 Positive_regulation of Fst 1 0.39 0 1.07
20 INT146897 Binding of Fst and OR13H1 1 0.01 0 1.05
21 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
22 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
23 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
24 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
25 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
26 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
27 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
28 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
29 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
30 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
31 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
32 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
33 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
34 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
35 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
36 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
37 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
38 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
39 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
40 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
41 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
42 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
43 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
44 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
45 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
46 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
47 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
48 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
49 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
50 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
51 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
52 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
53 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
54 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
55 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
56 INT137102 Fst Regulation of Sec22b 1 0.07 0 0.67
57 INT137101 Fst Regulation of Htr1a 1 0.24 0 0.67
58 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
59 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
60 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
61 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
62 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
63 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
64 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
65 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
66 INT144320 Binding of Fst and Rbm39 1 0.04 0 0.59
67 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
68 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
69 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
70 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
71 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
72 INT305744 Fst Positive_regulation of Creb1 1 0.12 0.33 0.57
73 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
74 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
75 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
76 INT17707 Binding of Calca and Iapp 1 0.42 0 0.54
77 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
78 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
79 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
80 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
81 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
82 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
83 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
84 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
85 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
86 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
87 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
88 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
89 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
90 INT135755 Pomc Positive_regulation of Positive_regulation of Id3 1 0.17 0 0.5
91 INT135752 Pomc Positive_regulation of Id3 1 0.16 0 0.5
92 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
93 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
94 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
95 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
96 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
97 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
98 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
99 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
100 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47
101 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
102 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
103 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
104 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
105 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
106 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
107 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
108 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
109 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
110 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
111 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
112 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
113 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
114 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
115 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
116 INT61345 Iapp Regulation of GAL 2 0.08 0.35 0.41
117 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
118 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
119 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
120 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
121 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
122 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
123 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
124 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
125 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
126 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39
127 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38
128 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
129 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
130 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
131 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36
132 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
133 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36
134 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35
135 INT213975 Binding of Iapp and Trav6-3 1 0.00 0.05 0.35
136 INT274865 Positive_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.04 1.08 0.35
137 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
138 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35
139 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
140 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
141 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
142 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
143 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34
144 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
145 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33
146 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
147 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
148 INT274866 Mapk1 Positive_regulation of Gene_expression of TNF 1 0.06 0.35 0.33
149 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
150 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
151 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
152 INT337112 Negative_regulation of Nr1d2-rs2 Positive_regulation of Mapk1 1 0.00 0.14 0.33
153 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33
154 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
155 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
156 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
157 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
158 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
159 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32
160 INT291241 Map3k8 Positive_regulation of Gene_expression of Mapk1 1 0.17 0.72 0.32
161 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
162 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
163 INT194710 MAPK1 Regulation of Gene_expression of IK 1 0.00 0.24 0.31
164 INT100029 TNF Positive_regulation of Mapk1 1 0.01 0.78 0.31
165 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
166 INT337111 Positive_regulation of Nr1d2-rs2 Negative_regulation of Positive_regulation of Mapk1 1 0.00 0.15 0.31
167 INT239558 Binding of CXCR2 and Hopx 1 0.06 0.44 0.31
168 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
169 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
170 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3
171 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
172 INT356287 Ngf Positive_regulation of Mapk1 1 0.05 0.17 0.3
173 INT304504 Mapk1 Positive_regulation of Nos1 1 0.29 0.93 0.3
174 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
175 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29
176 INT286705 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29
177 INT291254 MAP3K3 Regulation of Mapk1 1 0.00 1.25 0.29
178 INT291242 Positive_regulation of Mdk Regulation of Mapk1 1 0.03 1.28 0.29
179 INT286703 Mapk1 Positive_regulation of Phosphorylation of Hist1h3f 1 0.22 0.18 0.29
180 INT286706 Mapk1 Positive_regulation of Phosphorylation of Rps6ka5 1 0.37 0.18 0.29
181 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
182 INT112805 CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.29
183 INT286699 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.22 0.18 0.28
184 INT130107 YY1 Positive_regulation of MAPK1 1 0.45 0 0.28
185 INT132365 Lgals1 Positive_regulation of Mapk1 1 0.03 0.13 0.28
186 INT264472 Mapk1 Regulation of Positive_regulation of Jun 1 0.02 0 0.28
187 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28
188 INT286704 Mapk1 Positive_regulation of Phosphorylation of Creb1 1 0.32 0.18 0.28
189 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28
190 INT130106 Regulation of YY1 Positive_regulation of MAPK1 1 0.41 0 0.28
191 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28
192 INT286707 Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.28
193 INT130108 DLL3 Negative_regulation of Positive_regulation of MAPK1 1 0.13 0 0.28
194 INT207634 Prkca Negative_regulation of Positive_regulation of Mapk1 1 0.08 0.1 0.28
195 INT291257 Map3k8 Regulation of Positive_regulation of MAPK1 1 0.09 1 0.28
196 INT26669 Nanog Regulation of Binding of Tlyr1 1 0.02 0 0.28
197 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
198 INT141109 Sftpa1 Positive_regulation of Mapk1 1 0.77 0.65 0.27
199 INT194682 Negative_regulation of MAPK1 Positive_regulation of Gene_expression of IL10 1 0.05 0.17 0.27
200 INT270256 MAPK1 Positive_regulation of Mknk1 1 0.03 0.52 0.27

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
4 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
5 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
6 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
7 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
8 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
9 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
10 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
11 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
12 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
13 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
14 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
15 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
16 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
17 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
18 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
19 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
20 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
21 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
22 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
23 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
24 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
25 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
26 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
27 INT65277 Negative_regulation of Fst 20 0.43 4.61 11.83
28 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
29 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
30 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
31 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
32 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
33 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98
34 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
35 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
36 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
37 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
38 INT70572 Gene_expression of Fst 33 0.78 5.22 8.24
39 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
40 INT55859 Binding of Dll1 6 0.35 0 7.64
41 INT60931 Negative_regulation of Fst 15 0.57 5.44 7.21
42 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
43 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
44 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
45 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
46 INT86060 Positive_regulation of Fst 13 0.64 3.04 6.33
47 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
48 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
49 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
50 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
51 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
52 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
53 INT65276 Gene_expression of Fst 12 0.65 4.99 5.05
54 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
55 INT71406 Regulation of Dll1 3 0.35 0.79 4.44
56 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
57 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
58 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
59 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
60 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
61 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
62 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84
63 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
64 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
65 INT78733 Gene_expression of Iapp 20 0.78 12.99 3.33
66 INT49190 Regulation of Dll1 3 0.44 0.26 3.24
67 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
68 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
69 INT33237 Regulation of Fst 10 0.39 1.3 3
70 INT55148 Binding of Dll1 5 0.48 0.66 2.97
71 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
72 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
73 INT116540 Binding of Twist1 35 0.48 16.32 2.85
74 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
75 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
76 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
77 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
78 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
79 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
80 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
81 INT66891 Negative_regulation of Positive_regulation of Dll1 1 0.41 0 2.72
82 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
83 INT67329 Positive_regulation of Positive_regulation of Dll1 2 0.32 0 2.56
84 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
85 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
86 INT163580 Positive_regulation of Fst 4 0.19 2.85 2.17
87 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
88 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
89 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
90 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
91 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
92 INT138316 Regulation of Fst 5 0.44 1.15 1.99
93 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
94 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96
95 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
96 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
97 INT62692 Localization of Nanog 3 0.73 0.82 1.85
98 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
99 INT102861 Phosphorylation of Twist1 6 0.70 0.86 1.81
100 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77
101 INT159099 Negative_regulation of Positive_regulation of Dll1 1 0.25 0.74 1.76
102 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75
103 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
104 INT159100 Regulation of Positive_regulation of Dll1 1 0.26 0.7 1.73
105 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
106 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
107 INT159098 Negative_regulation of Gene_expression of Dll1 1 0.18 0.62 1.65
108 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
109 INT280933 Binding of Fst 4 0.12 3.53 1.63
110 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
111 INT169461 Regulation of Gene_expression of Mapk1 7 0.44 1.64 1.61
112 INT52757 Localization of Dll1 1 0.20 0 1.6
113 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59
114 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
115 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
116 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
117 INT140245 Binding of Gli3 3 0.36 2.65 1.46
118 INT67457 Binding of Rara 12 0.24 8.28 1.45
119 INT190646 Regulation of Regulation of Mapk1 1 0.30 1.16 1.43
120 INT102860 Positive_regulation of Phosphorylation of Twist1 1 0.35 0.15 1.42
121 INT153627 Binding of Mapk1 5 0.36 2.88 1.4
122 INT10873 Localization of Twist1 21 0.74 10.43 1.37
123 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36
124 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
125 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
126 INT81400 Binding of RARA 25 0.36 12.93 1.27
127 INT71106 Negative_regulation of Iapp 4 0.33 2.82 1.24
128 INT243621 Transcription of Twist1 13 0.71 4.08 1.23
129 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
130 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22
131 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
132 INT78730 Positive_regulation of Gene_expression of Iapp 4 0.48 3.58 1.2
133 INT110780 Localization of Notch1 2 0.06 0.47 1.19
134 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
135 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14
136 INT182985 Transcription of RARA 9 0.60 3.52 1.12
137 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
138 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
139 INT78731 Negative_regulation of Iapp 4 0.43 3.33 1.06
140 INT239527 Gene_expression of Hopx 1 0.26 0.5 1.06
141 INT165530 Positive_regulation of Shh 4 0.69 1.21 1.05
142 INT50071 Gene_expression of Iapp 4 0.58 3.51 1.03
143 INT104284 Positive_regulation of Notch3 7 0.50 5.57 0.99
144 INT250699 Binding of CDK6 3 0.33 2.54 0.97
145 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
146 INT6833 Binding of Notch1 4 0.36 0.05 0.94
147 INT280942 Localization of Fst 2 0.22 2.13 0.91
148 INT192090 Localization of Rara 6 0.46 4.15 0.89
149 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
150 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
151 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
152 INT304863 Negative_regulation of Gene_expression of Nanog 4 0.41 0.91 0.84
153 INT48250 Regulation of Rara 3 0.29 2.47 0.83
154 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
155 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82
156 INT212109 Localization of RARA 5 0.65 3.17 0.79
157 INT66992 Positive_regulation of Id3 2 0.43 0.23 0.78
158 INT303347 Positive_regulation of Gene_expression of Jag1 6 0.65 4.06 0.77
159 INT194780 Regulation of Negative_regulation of MAPK1 3 0.32 3.42 0.76
160 INT139089 Negative_regulation of Gene_expression of Dll1 2 0.43 0 0.69
161 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
162 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
163 INT91398 Regulation of RARA 7 0.59 5.84 0.67
164 INT54497 Binding of Nanog 1 0.35 0 0.67
165 INT156967 Localization of Fst 2 0.66 0.1 0.66
166 INT60547 Localization of Iapp 5 0.80 9.9 0.65
167 INT101726 Gene_expression of Notch3 4 0.77 4.87 0.64
168 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
169 INT156968 Negative_regulation of Localization of Fst 1 0.37 0.1 0.64
170 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
171 INT62732 Positive_regulation of Gene_expression of Nanog 2 0.45 0.27 0.63
172 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
173 INT113042 Localization of IHH 1 0.70 0.77 0.61
174 INT243616 Positive_regulation of Transcription of Twist1 6 0.69 2.09 0.6
175 INT50072 Positive_regulation of Gene_expression of Iapp 2 0.18 1.18 0.6
176 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
177 INT75524 Positive_regulation of Regulation of MAPK1 1 0.43 1.12 0.59
178 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58
179 INT68830 Transcription of Iapp 2 0.32 1.33 0.58
180 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
181 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
182 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
183 INT60546 Regulation of Iapp 2 0.45 0.36 0.56
184 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
185 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
186 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
187 INT190645 Positive_regulation of Negative_regulation of Mapk1 1 0.44 0.39 0.54
188 INT170475 Negative_regulation of Gene_expression of Mapk1 7 0.41 2.44 0.53
189 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
190 INT349703 Positive_regulation of Transcription of Fst 1 0.46 0.14 0.53
191 INT349725 Transcription of Fst 1 0.63 0.13 0.53
192 INT135062 Transcription of Gli3 1 0.05 0 0.52
193 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
194 INT135747 Gene_expression of Id3 1 0.52 0 0.5
195 INT109911 Positive_regulation of Localization of MAPK1 4 0.33 0.56 0.48
196 INT172794 Localization of Iapp 2 0.72 3.18 0.48
197 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
198 INT304861 Regulation of Gene_expression of Nanog 3 0.43 0.13 0.46
199 INT206484 Localization of Shh 2 0.75 1.14 0.46
200 INT159151 Negative_regulation of Negative_regulation of Mapk1 1 0.32 0.38 0.45
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