GO:0045598

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Name regulation of fat cell differentiation
Categary Process
Go Slim No
Go Link GO:0045598
Unique Molecular Interactions 103
Total Molecular Interactions 119
Total Single Events 1523
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
2 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
3 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
4 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61
5 INT145726 Binding of Abcb1a and Alms1 1 0.32 0.48 0.56
6 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
7 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
8 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29
9 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
10 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
11 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
12 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
13 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18
14 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18
15 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
16 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17
17 INT81297 Positive_regulation of Pparg Regulation of Gene_expression of Nos2 1 0.23 0.17 0.17
18 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17
19 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17
20 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17
21 INT106506 Binding of Pparg and Ptgds 1 0.42 0.31 0.14
22 INT338449 Nps Regulation of Alms1 1 0.04 0.13 0.14
23 INT308534 Binding of HIVEP1 and Alms1 1 0.00 0.96 0.13
24 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13
25 INT101173 Pparg Regulation of Positive_regulation of Nfkb1 1 0.03 0.07 0.12
26 INT101174 Pparg Regulation of Gene_expression of IK 1 0.00 0.07 0.12
27 INT100478 Binding of Camk1d and Alms1 1 0.17 0 0.12
28 INT187468 Alms1 Positive_regulation of H2-D1 1 0.02 0.32 0.11
29 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11
30 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
31 INT289536 Sirt1 Negative_regulation of Localization of Pparg 1 0.13 0.43 0.08
32 INT110377 Binding of Ncoa1 and Pparg 1 0.02 0.26 0.08
33 INT265609 Msc Positive_regulation of TAF8 1 0.03 0.7 0.08
34 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
35 INT243213 Myst2 Negative_regulation of Alms1 1 0.01 0.91 0.08
36 INT289533 Sirt1 Negative_regulation of Pparg 1 0.18 0.42 0.07
37 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04
38 INT120449 Pparg Positive_regulation of Negative_regulation of Il2 1 0.75 0 0.04
39 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
40 INT251067 Plvap Regulation of Protein_catabolism of Alms1 1 0.03 0 0.03
41 INT251074 Cldn3 Regulation of Protein_catabolism of Alms1 1 0.09 0 0.03
42 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0
43 INT187621 Gnrh1 Regulation of Gene_expression of Pparg 1 0.00 0.09 0
44 INT251071 Cldn3 Negative_regulation of Alms1 1 0.09 0.26 0
45 INT265610 Positive_regulation of TAF8 Positive_regulation of Msc 1 0.03 0.89 0
46 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0
47 INT283715 Lpin1 Regulation of 4930579C15Rik 1 0.35 0.74 0
48 INT345168 Binding of Lpar1 and Ppard 1 0.03 0.21 0
49 INT327830 Alms1 Positive_regulation of Aqp4 1 0.03 0.15 0
50 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
51 INT86001 Binding of Pnp and Alms1 1 0.03 0 0
52 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
53 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
54 INT284391 Binding of AMT and Alms1 1 0.00 0 0
55 INT305884 Atp6v0a2 Regulation of Alms1 1 0.00 0 0
56 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
57 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
58 INT86004 Binding of PBCA and Alms1 1 0.01 0 0
59 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0
60 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0
61 INT211570 Kit Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
62 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0
63 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
64 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
65 INT130602 Pparg Regulation of Pscs 1 0.11 0.29 0
66 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
67 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0
68 INT187623 Lhb Regulation of Gene_expression of Pparg 1 0.02 0.09 0
69 INT211577 Vldlr Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
70 INT235692 Clcn1 Positive_regulation of Binding of Alms1 1 0.05 0.9 0
71 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
72 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
73 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
74 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
75 INT305882 Binding of Pcx and Alms1 1 0.03 0.62 0
76 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0
77 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
78 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
79 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
2 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
3 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
4 INT36177 Binding of Alms1 70 0.31 35.47 13.81
5 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
6 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
7 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
8 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
9 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
10 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
11 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
12 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
13 INT67609 Binding of Pparg 17 0.46 9.53 6.06
14 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
15 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
16 INT108761 Localization of Alms1 24 0.70 13.92 3.74
17 INT78845 Binding of Pparg 16 0.44 11.67 3.53
18 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
19 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
20 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
21 INT112758 Binding of Ppard 7 0.37 3.6 2.87
22 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
23 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
24 INT78844 Regulation of Pparg 6 0.41 4 2.19
25 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95
26 INT117438 Positive_regulation of Gene_expression of Pparg 11 0.69 8 1.63
27 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
28 INT154497 Gene_expression of Ptprq 3 0.04 0.91 1.31
29 INT132495 Negative_regulation of Gene_expression of Ppard 4 0.44 2.64 1.28
30 INT98817 Regulation of Pparg 3 0.26 1.62 1.03
31 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02
32 INT112759 Negative_regulation of Binding of Ppard 2 0.39 2.08 0.99
33 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96
34 INT173514 Negative_regulation of Gene_expression of Alms1 3 0.06 3.49 0.91
35 INT103400 Transcription of Pparg 2 0.67 3.15 0.85
36 INT230493 Regulation of Binding of Alms1 3 0.12 1.89 0.76
37 INT94148 Positive_regulation of Binding of Pparg 2 0.43 1.16 0.66
38 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
39 INT116288 Negative_regulation of Pparg 4 0.42 1.69 0.62
40 INT289903 Regulation of Localization of Alms1 2 0.14 1.48 0.56
41 INT130600 Negative_regulation of Binding of Pparg 1 0.42 1.96 0.54
42 INT230495 Regulation of Gene_expression of Alms1 4 0.04 4.53 0.53
43 INT144098 Localization of Pparg 2 0.59 0.73 0.52
44 INT158946 Negative_regulation of Pparg 3 0.43 1.53 0.51
45 INT354813 Positive_regulation of Negative_regulation of Alms1 1 0.04 0.82 0.48
46 INT242443 Positive_regulation of Localization of Alms1 2 0.09 0.66 0.46
47 INT132946 Negative_regulation of Positive_regulation of Ppard 1 0.42 0.09 0.44
48 INT98818 Regulation of Positive_regulation of Pparg 1 0.03 0.14 0.41
49 INT308524 Regulation of Protein_catabolism of Alms1 1 0.06 1.04 0.4
50 INT78849 Transcription of Pparg 3 0.53 2.31 0.38
51 INT265606 Positive_regulation of TAF8 6 0.35 3.42 0.37
52 INT81290 Positive_regulation of Positive_regulation of Pparg 1 0.45 0.37 0.36
53 INT265607 Gene_expression of TAF8 11 0.32 9.91 0.35
54 INT78847 Positive_regulation of Transcription of Pparg 2 0.44 0.47 0.35
55 INT154243 Positive_regulation of Binding of Alms1 4 0.42 1.86 0.32
56 INT144419 Regulation of Ppard 1 0.24 0.91 0.3
57 INT61115 Localization of Ppard 2 0.66 1.99 0.28
58 INT159198 Positive_regulation of Binding of Ppard 1 0.34 0.68 0.28
59 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
60 INT214353 Negative_regulation of Gene_expression of Ptprq 1 0.03 0 0.27
61 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
62 INT166885 Negative_regulation of Gene_expression of Pparg 5 0.41 2.6 0.26
63 INT214347 Binding of Ptprq 2 0.09 0.23 0.26
64 INT243208 Negative_regulation of Protein_catabolism of Alms1 2 0.06 2.21 0.26
65 INT158945 Negative_regulation of Negative_regulation of Pparg 1 0.43 0.73 0.26
66 INT78848 Regulation of Binding of Pparg 1 0.45 0.5 0.25
67 INT283693 Transcription of Lpin1 1 0.67 1.31 0.22
68 INT178257 Positive_regulation of Transcription of Pparg 1 0.49 2.25 0.21
69 INT265608 Localization of TAF8 3 0.46 1.94 0.2
70 INT295891 Positive_regulation of Positive_regulation of Alms1 1 0.02 0.48 0.2
71 INT214352 Regulation of Ptprq 1 0.02 0.17 0.2
72 INT161753 Regulation of Gene_expression of Pparg 2 0.35 1.28 0.19
73 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18
74 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
75 INT81292 Regulation of Positive_regulation of Pparg 1 0.41 0.17 0.17
76 INT101172 Localization of Pparg 6 0.58 3.62 0.12
77 INT211536 Binding of Lpin1 2 0.46 1.06 0.12
78 INT243206 Negative_regulation of Localization of Alms1 1 0.05 0.98 0.12
79 INT78846 Negative_regulation of Regulation of Pparg 1 0.32 0.23 0.12
80 INT229009 Positive_regulation of Localization of Pparg 1 0.39 1.86 0.1
81 INT344823 Negative_regulation of Negative_regulation of Alms1 1 0.04 1.04 0.07
82 INT344812 Negative_regulation of Binding of Alms1 1 0.04 1.04 0.07
83 INT283679 Positive_regulation of Lpin1 1 0.48 0.57 0.07
84 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06
85 INT283677 Localization of Lpin1 1 0.32 0.37 0.05
86 INT211538 Negative_regulation of Lpin1 1 0.57 1.28 0.04
87 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
88 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
89 INT319131 Positive_regulation of Lrp5 1 0.43 0.36 0.03
90 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
91 INT297757 Transcription of Lrp5 2 0.68 0.82 0
92 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
93 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0
94 INT264708 Transcription of Hes1 1 0.67 0.83 0
95 INT239508 Transcription of Alms1 1 0.20 0 0
96 INT259385 Positive_regulation of Ptprq 1 0.09 0 0
97 INT264705 Binding of Hes1 1 0.35 0.07 0
98 INT211543 Regulation of Lpin1 1 0.60 0.28 0
99 INT229010 Phosphorylation of Pparg 1 0.63 2.95 0
100 INT342375 Positive_regulation of Binding of Lrp5 1 0.46 0.85 0
101 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
102 INT259386 Negative_regulation of Ptprq 1 0.08 0.06 0
103 INT211562 Positive_regulation of Gene_expression of Lpin1 1 0.49 0.27 0
104 INT211545 Negative_regulation of Gene_expression of Lpin1 1 0.42 0.38 0
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