GO:0045599

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Name negative regulation of fat cell differentiation
Categary Process
Go Slim No
Go Link GO:0045599
Unique Molecular Interactions 1794
Total Molecular Interactions 2478
Total Single Events 20256
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
2 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
3 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
4 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
5 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
6 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
7 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
8 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
9 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
10 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
11 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
12 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
13 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
14 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
15 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
16 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
17 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
18 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
19 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
20 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
21 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
22 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
23 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
24 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
25 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
26 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
27 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
28 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
29 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
30 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
31 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
32 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
33 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
34 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
35 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
36 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
37 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
38 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
39 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
40 INT340300 Ea1 Positive_regulation of Gene_expression of Sirt1 1 0.08 1.68 1.49
41 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
42 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
43 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
44 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
45 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
46 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
47 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
48 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
49 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
50 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
51 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
52 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
53 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
54 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
55 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
56 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
57 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
58 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
59 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
60 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
61 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
62 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
63 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
64 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
65 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
66 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
67 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
68 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
69 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
70 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
71 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
72 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
73 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
74 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
75 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
76 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
77 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
78 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
79 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
80 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
81 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
82 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
83 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
84 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
85 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
86 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
87 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
88 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
89 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
90 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
91 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
92 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
93 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
94 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
95 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
96 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
97 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
98 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
99 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
100 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
101 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
102 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
103 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
104 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
105 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
106 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
107 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
108 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
109 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
110 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
111 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
112 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
113 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
114 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
115 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
116 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
117 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
118 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
119 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
120 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
121 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
122 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
123 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
124 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
125 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
126 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
127 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
128 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
129 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
130 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
131 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
132 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
133 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
134 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
135 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
136 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
137 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
138 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
139 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
140 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
141 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
142 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
143 INT261480 Negative_regulation of Trib3 Positive_regulation of Ephb1 1 0.04 0.8 0.84
144 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
145 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
146 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
147 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
148 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
149 INT340294 Ea1 Positive_regulation of Sirt1 1 0.06 0.53 0.83
150 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
151 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
152 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
153 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
154 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
155 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
156 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
157 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
158 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
159 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
160 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
161 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
162 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
163 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
164 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
165 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
166 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
167 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
168 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
169 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
170 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
171 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
172 INT50708 Phax Positive_regulation of Trib3 1 0.03 0.07 0.77
173 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
174 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
175 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76
176 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
177 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
178 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
179 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
180 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
181 INT50707 Phax Positive_regulation of Positive_regulation of Trib3 1 0.04 0.16 0.74
182 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
183 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
184 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
185 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
186 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
187 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
188 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
189 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
190 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
191 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
192 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
193 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
194 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
195 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
196 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
197 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
198 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
199 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
200 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of fat cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of fat cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
9 INT9660 Regulation of TNF 363 0.62 312.94 139.99
10 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
11 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
12 INT12082 Localization of IL6 365 0.81 241.78 105.78
13 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
14 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
15 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
16 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
17 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
18 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
19 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
20 INT9210 Regulation of IL6 166 0.62 125.61 49.95
21 INT13354 Transcription of TNF 108 0.72 85.81 42.32
22 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
23 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
24 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
25 INT86437 Binding of IL6 154 0.48 121.22 29.3
26 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
27 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
28 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
29 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
30 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
31 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
32 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
33 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
34 INT61626 Transcription of IL6 73 0.72 42.04 17.86
35 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
36 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
37 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
38 INT38253 Localization of Trib3 35 0.63 10.28 15.42
39 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
40 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
41 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
42 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
43 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
44 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
45 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
46 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
47 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
48 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
49 INT33127 Positive_regulation of Phosphorylation of Trib3 26 0.17 14.04 10
50 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
51 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
52 INT10533 Positive_regulation of Positive_regulation of Trib3 24 0.42 6.59 9.2
53 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
54 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
55 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64
56 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
57 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
58 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17
59 INT39282 Negative_regulation of SOD2 27 0.59 16.89 7.03
60 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99
61 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
62 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
63 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
64 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
65 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
66 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
67 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
68 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
69 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
70 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53
71 INT50704 Binding of Trib3 13 0.31 6.33 5.46
72 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
73 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
74 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
75 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
76 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
77 INT51734 Negative_regulation of Localization of Trib3 10 0.19 2.53 4.97
78 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
79 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68
80 INT24813 Negative_regulation of Positive_regulation of Trib3 10 0.16 1.3 4.48
81 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
82 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
83 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
84 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
85 INT32205 Regulation of Positive_regulation of Trib3 9 0.11 2.82 4.1
86 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
87 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92
88 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
89 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
90 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
91 INT10535 Positive_regulation of Gene_expression of Trib3 13 0.59 4.93 3.74
92 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71
93 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
94 INT99453 Gene_expression of SOD2 25 0.77 13.28 3.6
95 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
96 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
97 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
98 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
99 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
100 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
101 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
102 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
103 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
104 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
105 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
106 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
107 INT15327 Negative_regulation of Phosphorylation of Trib3 7 0.30 4.95 2.99
108 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
109 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
110 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
111 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
112 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
113 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
114 INT33492 Negative_regulation of Negative_regulation of Trib3 5 0.30 0.51 2.67
115 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
116 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
117 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
118 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
119 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
120 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
121 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
122 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
123 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
124 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
125 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
126 INT249563 Positive_regulation of Trib3 1 0.45 0.94 2.18
127 INT249555 Localization of Trib3 1 0.73 0.94 2.18
128 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
129 INT109334 Regulation of SOD2 13 0.60 7.48 2.14
130 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
131 INT221409 Regulation of Sirt1 8 0.58 5.53 2.1
132 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
133 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
134 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
135 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
136 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
137 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
138 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
139 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
140 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
141 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
142 INT32469 Regulation of Gene_expression of Trib3 5 0.07 2.33 1.7
143 INT48752 Regulation of Negative_regulation of Trib3 3 0.39 0.89 1.65
144 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
145 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
146 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
147 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
148 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
149 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51
150 INT178615 Binding of SOD2 12 0.48 6.93 1.51
151 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
152 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5
153 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
154 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47
155 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
156 INT116014 Transcription of Gata3 4 0.63 2.24 1.46
157 INT270631 Gene_expression of Insig1 15 0.32 5.19 1.43
158 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
159 INT116015 Regulation of Gata3 3 0.22 1.41 1.42
160 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
161 INT116008 Binding of Gata3 2 0.34 1.37 1.41
162 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
163 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
164 INT99639 Regulation of Phosphorylation of Trib3 6 0.14 0.44 1.36
165 INT190880 Binding of Ncor2 11 0.27 2.24 1.34
166 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
167 INT116016 Positive_regulation of Positive_regulation of Gata3 2 0.21 0.5 1.28
168 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
169 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
170 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
171 INT108519 Binding of Lrp6 8 0.44 1.47 1.19
172 INT134061 Transcription of Sod2 5 0.68 3.46 1.19
173 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
174 INT83061 Regulation of Localization of Trib3 2 0.07 0.11 1.17
175 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
176 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
177 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
178 INT133079 Positive_regulation of Gene_expression of GATA3 3 0.50 1.03 1.11
179 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
180 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03
181 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
182 INT168065 Binding of Sirt1 13 0.47 4.55 1.02
183 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
184 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
185 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
186 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
187 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
188 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
189 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9
190 INT48931 Regulation of Regulation of Trib3 2 0.04 0.06 0.89
191 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
192 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
193 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
194 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
195 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
196 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
197 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
198 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
199 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8
200 INT103823 Positive_regulation of Gene_expression of SOD2 10 0.68 4.69 0.79
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