GO:0045616

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Name regulation of keratinocyte differentiation
Categary Process
Go Slim No
Go Link GO:0045616
Unique Molecular Interactions 48
Total Molecular Interactions 63
Total Single Events 353
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of keratinocyte differentiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of keratinocyte differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
2 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
3 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43
4 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
5 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
6 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2
7 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18
8 INT251349 Ifnar1 Positive_regulation of Rock1 1 0.01 1.27 0.16
9 INT120553 Y-27632 Negative_regulation of Rock1 1 0.01 0.15 0.15
10 INT120552 Y-27632 Negative_regulation of Rock2 1 0.02 0.15 0.15
11 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12
12 INT321965 Rock1 Positive_regulation of Nos3 1 0.28 1.99 0.12
13 INT263427 Pdgfb Positive_regulation of Phosphorylation of Rock1 1 0.00 0 0.04
14 INT220811 Tert Positive_regulation of Gene_expression of Krt36 1 0.41 0.14 0.04
15 INT269584 Binding of CFL1 and ROCK1 1 0.03 0.05 0.03
16 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03
17 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
18 INT241460 Rock1 Positive_regulation of Phosphorylation of MLC1 1 0.38 0.63 0.03
19 INT181079 Binding of Akt1 and Errfi1 1 0.00 0.8 0.03
20 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03
21 INT159960 Rock2 Regulation of Phosphorylation of Tnf 1 0.04 0.55 0.03
22 INT303010 Ptgis Positive_regulation of Rock2 1 0.05 1.23 0.03
23 INT241456 Tgtp1 Positive_regulation of Rock1 1 0.01 0 0
24 INT241448 Binding of Rock1 and Tgtp1 1 0.01 0 0
25 INT258209 ROCK1 Regulation of ARR3 1 0.00 0.2 0
26 INT254866 Positive_regulation of C3 Negative_regulation of Rock1 1 0.02 0 0
27 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0
28 INT181078 Binding of Errfi1 and Cdc42ep3 1 0.00 0.73 0
29 INT254861 C3 Negative_regulation of Rock1 1 0.02 0 0
30 INT321969 Negative_regulation of Rock1 Negative_regulation of VEGFA 1 0.03 0.65 0
31 INT159959 Gtf3a Positive_regulation of Phosphorylation of Rock2 1 0.01 0.5 0
32 INT180124 Rhob Positive_regulation of Rock1 1 0.14 0 0
33 INT353439 Negative_regulation of Rock1 Negative_regulation of Hc3 1 0.08 0.2 0
34 INT353436 Rock1 Positive_regulation of Myo1f 1 0.02 0.23 0
35 INT321968 Rock1 Positive_regulation of EZR 1 0.42 1.02 0
36 INT353434 Binding of Rock1 and Rnd3 1 0.22 0.26 0
37 INT353435 Binding of Pdpk1 and Rock1 1 0.09 0.27 0
38 INT254856 Tgfb1 Negative_regulation of Rock1 1 0.01 0 0
39 INT180125 Rhoa Positive_regulation of Rock1 1 0.14 0 0
40 INT261730 ROCK1 Positive_regulation of Positive_regulation of F2R 1 0.37 0 0
41 INT345184 Lpar1 Positive_regulation of Rock1 1 0.00 0.62 0
42 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0
43 INT159966 TNF Positive_regulation of Phosphorylation of Rock2 1 0.01 0.5 0
44 INT353438 Rnd3 Negative_regulation of Rock1 1 0.26 2.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of keratinocyte differentiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of keratinocyte differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123563 Negative_regulation of Rock1 7 0.55 16.56 5.78
2 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66
3 INT123564 Negative_regulation of Rock2 13 0.59 9.61 3.58
4 INT120551 Negative_regulation of Rock2 8 0.52 2.73 2.53
5 INT168720 Regulation of Negative_regulation of Rock1 1 0.43 1.31 1.23
6 INT180095 Gene_expression of Rock1 22 0.55 4.9 1.14
7 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
8 INT146198 Positive_regulation of Rock1 16 0.49 5.86 1.1
9 INT146553 Positive_regulation of Rock2 4 0.44 2.56 1.09
10 INT263403 Positive_regulation of Rock1 3 0.38 4.68 1.09
11 INT111858 Regulation of Rock1 1 0.41 0.75 1.09
12 INT136044 Gene_expression of Rock2 7 0.78 0.19 1.06
13 INT146199 Negative_regulation of Negative_regulation of Rock1 1 0.22 0.7 0.8
14 INT167608 Regulation of Rock2 2 0.33 2.47 0.59
15 INT136043 Negative_regulation of Gene_expression of Rock2 1 0.43 0 0.53
16 INT126628 Positive_regulation of Rock2 4 0.70 3.56 0.52
17 INT146189 Positive_regulation of Positive_regulation of Rock1 2 0.26 1.27 0.47
18 INT263390 Phosphorylation of Rock1 1 0.17 0 0.41
19 INT263413 Positive_regulation of Phosphorylation of Rock1 1 0.11 0 0.37
20 INT180106 Regulation of Rock1 5 0.31 2.37 0.36
21 INT263400 Positive_regulation of Positive_regulation of Rock1 1 0.11 0.4 0.34
22 INT126627 Gene_expression of Rock2 9 0.60 3.33 0.32
23 INT180105 Localization of Rock1 2 0.53 0.66 0.31
24 INT202595 Gene_expression of Krt36 11 0.56 0.5 0.3
25 INT185436 Gene_expression of ROCK1 5 0.52 6.85 0.29
26 INT85329 Regulation of Errfi1 1 0.01 0.39 0.28
27 INT202596 Negative_regulation of Krt36 1 0.19 0.27 0.27
28 INT147486 Negative_regulation of Positive_regulation of Rock2 1 0.06 1.67 0.24
29 INT258250 Positive_regulation of ROCK1 7 0.51 2.07 0.22
30 INT180115 Phosphorylation of Rock1 5 0.58 1.21 0.22
31 INT185443 Regulation of ROCK1 4 0.18 3.32 0.21
32 INT159956 Phosphorylation of Rock2 3 0.79 1.57 0.2
33 INT202690 Positive_regulation of Krt36 2 0.49 0.05 0.19
34 INT263407 Binding of Rock2 1 0.02 0 0.18
35 INT180092 Positive_regulation of Gene_expression of Rock1 6 0.36 0.95 0.16
36 INT241419 Binding of Rock1 4 0.25 1.93 0.16
37 INT126625 Transcription of Rock2 1 0.67 0 0.09
38 INT306176 Localization of Rock2 1 0.73 0.41 0.09
39 INT126624 Negative_regulation of Transcription of Rock2 1 0.41 0 0.09
40 INT321962 Negative_regulation of Positive_regulation of Rock1 1 0.33 1.17 0.07
41 INT202597 Localization of Krt36 1 0.39 0.12 0.05
42 INT341887 Positive_regulation of Positive_regulation of ROCK1 1 0.01 0.12 0.05
43 INT344635 Negative_regulation of Binding of Rock1 1 0.04 0.24 0.04
44 INT343555 Regulation of Gene_expression of ROCK1 1 0.15 1.02 0.04
45 INT192237 Phosphorylation of ROCK1 2 0.19 0.39 0.03
46 INT343556 Positive_regulation of Gene_expression of ROCK1 1 0.23 1.05 0.03
47 INT180102 Regulation of Protein_catabolism of Rock1 1 0.32 0.27 0.03
48 INT180111 Protein_catabolism of Rock1 1 0.63 0.27 0.03
49 INT180110 Regulation of Positive_regulation of Rock1 2 0.32 0.24 0
50 INT269651 Positive_regulation of Phosphorylation of ROCK1 1 0.11 0.29 0
51 INT258237 Negative_regulation of Negative_regulation of ROCK1 1 0.32 0.16 0
52 INT180093 Negative_regulation of Gene_expression of Rock1 1 0.30 0.07 0
53 INT353419 Positive_regulation of Negative_regulation of Rock1 1 0.20 0.2 0
54 INT180112 Positive_regulation of Phosphorylation of Rock1 1 0.36 0 0
55 INT202594 Regulation of Gene_expression of Krt36 1 0.20 0 0
56 INT202598 Positive_regulation of Gene_expression of Krt36 1 0.26 0.09 0
57 INT202691 Negative_regulation of Gene_expression of Krt36 1 0.09 0 0
58 INT321961 Gene_expression of Rock1 1 0.51 0.79 0
59 INT321964 Binding of Rock1 1 0.28 0.96 0
60 INT353416 Regulation of Gene_expression of Rock1 1 0.18 0 0
61 INT353432 Positive_regulation of Regulation of Rock1 1 0.19 0.24 0
62 INT306177 Regulation of Gene_expression of Rock2 1 0.26 0.84 0
63 INT269645 Negative_regulation of Positive_regulation of ROCK1 1 0.10 0 0
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