GO:0045626

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Name negative regulation of T-helper 1 cell differentiation
Categary Process
Go Slim No
Go Link GO:0045626
Unique Molecular Interactions 12
Total Molecular Interactions 15
Total Single Events 115
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of T-helper 1 cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of T-helper 1 cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231751 Binding of Il2rg and Jak3 1 0.03 1.56 0.67
2 INT231750 LOC690550 Negative_regulation of Jak3 1 0.02 1.3 0.52
3 INT278957 JAK3 Positive_regulation of Gene_expression of IL8 1 0.28 0.67 0.38
4 INT278955 JAK3 Positive_regulation of Gene_expression of PRKCA 1 0.12 0.65 0.37
5 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
6 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22
7 INT237748 Negative_regulation of Jak3 Negative_regulation of Positive_regulation of Stat3 1 0.25 1.01 0.22
8 INT261759 Binding of Il13 and Il4ra 1 0.26 0.51 0.2
9 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18
10 INT172824 Positive_regulation of Binding of Tnfsf4 and T2dm2 1 0.00 2.97 0.12
11 INT172831 Binding of INS and Tnfsf4 1 0.02 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of T-helper 1 cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of T-helper 1 cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT145299 Negative_regulation of Jak3 25 0.48 17.66 7.13
2 INT158573 Negative_regulation of Jak3 3 0.43 8.2 3.99
3 INT145298 Gene_expression of Jak3 5 0.78 7.69 3.07
4 INT145297 Positive_regulation of Jak3 3 0.50 5.52 2.14
5 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69
6 INT278975 Gene_expression of JAK3 3 0.52 1.03 0.97
7 INT226480 Positive_regulation of JAK3 4 0.45 0.96 0.95
8 INT174797 Regulation of Tnfsf4 1 0.03 4.05 0.54
9 INT237738 Positive_regulation of Gene_expression of Jak3 1 0.32 1.98 0.49
10 INT237739 Gene_expression of Jak3 1 0.44 1.97 0.48
11 INT345936 Regulation of JAK3 1 0.02 0.41 0.46
12 INT172800 Binding of Tnfsf4 2 0.04 4.58 0.45
13 INT172801 Positive_regulation of Tnfsf4 4 0.08 7.95 0.44
14 INT231744 Negative_regulation of Gene_expression of Jak3 1 0.32 0.9 0.43
15 INT278972 Regulation of Negative_regulation of JAK3 1 0.21 0.36 0.37
16 INT174805 Gene_expression of Tnfsf4 1 0.04 3.49 0.28
17 INT328812 Binding of Jak3 1 0.24 0.33 0.26
18 INT293346 Binding of JAK3 1 0.12 0.34 0.26
19 INT328816 Regulation of Negative_regulation of Jak3 1 0.30 0.88 0.24
20 INT278139 Regulation of Jak3 1 0.06 0.97 0.22
21 INT278146 Localization of Jak3 1 0.35 0.97 0.22
22 INT261747 Gene_expression of Il4ra 1 0.22 0.58 0.21
23 INT261749 Binding of Il4ra 1 0.26 0.51 0.2
24 INT278142 Binding of Jak3 1 0.17 0.67 0.19
25 INT278141 Negative_regulation of Negative_regulation of Jak3 1 0.20 0.66 0.15
26 INT172790 Negative_regulation of Tnfsf4 1 0.05 2.43 0.14
27 INT237736 Positive_regulation of Jak3 1 0.37 0.33 0.12
28 INT172785 Positive_regulation of Binding of Tnfsf4 1 0.05 2.89 0.12
29 INT278140 Regulation of Negative_regulation of Jak3 1 0.21 0.43 0.11
30 INT278144 Positive_regulation of Negative_regulation of Jak3 1 0.23 0.55 0.11
31 INT228800 Regulation of Gene_expression of Jak3 1 0.13 0.29 0.09
32 INT174802 Positive_regulation of Regulation of Tnfsf4 1 0.03 0.92 0.06
33 INT174799 Regulation of Binding of Tnfsf4 1 0.03 0.92 0.04
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