GO:0045627

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Name positive regulation of T-helper 1 cell differentiation
Categary Process
Go Slim No
Go Link GO:0045627
Unique Molecular Interactions 38
Total Molecular Interactions 100
Total Single Events 537
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of T-helper 1 cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of T-helper 1 cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
3 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
4 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
5 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
6 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
7 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
8 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48
9 INT149121 Binding of CD80 and Cd28 2 0.04 0.95 0.46
10 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42
11 INT287819 Binding of CD80 and Cd28 1 0.25 0.7 0.4
12 INT287818 Negative_regulation of Binding of CD80 and Cd28 1 0.29 0.7 0.4
13 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
14 INT353020 Binding of CD80 and Positive_regulation of Gene_expression of CD28 1 0.13 0.35 0.34
15 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
16 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
17 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31
18 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
19 INT289959 Negative_regulation of Binding of CD28 and CD80 1 0.07 0.24 0.23
20 INT289953 Binding of CD80 and KLF1 1 0.00 0.21 0.23
21 INT252366 Binding of RUNX1 and CD80 1 0.01 0.54 0.2
22 INT55252 Binding of CCK and RIPK2 1 0.40 0 0.2
23 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19
24 INT184086 Socs5 Negative_regulation of Binding of Jak1 1 0.20 0 0.16
25 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16
26 INT184098 Binding of Il4 and Socs5 1 0.09 2.05 0.15
27 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
28 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13
29 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13
30 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12
31 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12
32 INT351032 Binding of CD80 and CD96 1 0.01 0.36 0.09
33 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
34 INT352074 ADAM11 Positive_regulation of Gene_expression of CCL19 1 0.17 0.74 0.03
35 INT349079 Binding of CD80 and Cd86 1 0.22 0 0
36 INT184137 Binding of Socs5 and Regulation of Hand2 1 0.09 1.01 0
37 INT301674 Binding of APC and CD80 1 0.01 0.53 0
38 INT277808 Binding of APCS and CD80 1 0.11 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of T-helper 1 cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of T-helper 1 cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
2 INT132178 Binding of CD80 41 0.47 15.55 12.98
3 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
4 INT93914 Gene_expression of CD80 70 0.75 36.35 7.74
5 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
6 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22
7 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
8 INT20459 Regulation of Ripk2 5 0.44 0 4.53
9 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2
10 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98
11 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77
12 INT108484 Gene_expression of CCL19 4 0.50 12.56 3.63
13 INT6025 Negative_regulation of RIPK2 4 0.57 0.96 2.82
14 INT19421 Positive_regulation of RIPK2 6 0.49 5.63 2.72
15 INT61004 Negative_regulation of Regulation of Ripk2 1 0.41 0 2.68
16 INT146504 Regulation of Ccr2 5 0.39 3.58 2.21
17 INT97134 Negative_regulation of CD80 8 0.57 5.09 2.11
18 INT37977 Negative_regulation of Ripk2 3 0.42 0.92 2.03
19 INT93912 Positive_regulation of CD80 11 0.56 7.01 1.88
20 INT108486 Positive_regulation of Gene_expression of CCL19 2 0.45 6.2 1.79
21 INT181341 Binding of Ccr2 8 0.32 6.47 1.77
22 INT37978 Localization of Ripk2 4 0.78 0.57 1.73
23 INT147636 Regulation of CD80 3 0.60 1.27 1.73
24 INT55511 Positive_regulation of Binding of Ripk2 1 0.49 0.19 1.69
25 INT102550 Positive_regulation of Gene_expression of Ccr2 6 0.69 4.53 1.67
26 INT209896 Positive_regulation of Gene_expression of CD80 19 0.49 11.9 1.59
27 INT209959 Negative_regulation of Binding of CD80 3 0.42 0.9 1.52
28 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44
29 INT39144 Gene_expression of RIPK2 5 0.75 2.56 1.27
30 INT38502 Gene_expression of Ripk2 3 0.65 0.17 1.16
31 INT152010 Positive_regulation of Ccr7 3 0.47 1.46 1.15
32 INT181354 Binding of Ccr7 2 0.23 1.94 1.01
33 INT19422 Protein_catabolism of RIPK2 2 0.86 0.62 0.97
34 INT36850 Negative_regulation of Negative_regulation of RIPK2 1 0.57 0 0.97
35 INT38426 Regulation of RIPK2 3 0.60 0.62 0.91
36 INT42076 Regulation of Negative_regulation of RIPK2 1 0.44 0.91 0.91
37 INT55512 Positive_regulation of Localization of Ripk2 1 0.67 0.09 0.85
38 INT40227 Regulation of Positive_regulation of Ripk2 1 0.44 0 0.82
39 INT161223 Negative_regulation of Positive_regulation of Ccr2 1 0.43 0.83 0.81
40 INT37975 Negative_regulation of Binding of Ripk2 1 0.57 0 0.75
41 INT184019 Gene_expression of Socs5 6 0.53 4.94 0.72
42 INT147635 Regulation of Positive_regulation of CD80 1 0.44 0.38 0.53
43 INT147456 Negative_regulation of Positive_regulation of CD80 2 0.41 1.32 0.5
44 INT19420 Positive_regulation of Positive_regulation of RIPK2 1 0.49 0.59 0.5
45 INT236350 Transcription of Ccr2 2 0.72 3.59 0.49
46 INT354384 Regulation of CCL19 1 0.23 1.89 0.47
47 INT272877 Localization of Ccr2 2 0.75 1.68 0.46
48 INT38738 Localization of RIPK2 2 0.68 0.07 0.45
49 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43
50 INT340642 Regulation of Gene_expression of Ccr2 1 0.62 2.26 0.35
51 INT97137 Negative_regulation of Gene_expression of CD80 7 0.33 3.39 0.34
52 INT305840 Positive_regulation of Gene_expression of Ccr7 1 0.27 0.25 0.24
53 INT220167 Localization of Ccr7 1 0.31 0.39 0.18
54 INT201691 Binding of RIPK2 2 0.18 1.51 0.17
55 INT240596 Negative_regulation of Gene_expression of RIPK2 1 0.06 0.91 0.15
56 INT136002 Positive_regulation of Gene_expression of RIPK2 1 0.67 0.52 0.15
57 INT144094 Negative_regulation of Localization of Ripk2 1 0.42 0.49 0.09
58 INT236358 Regulation of Transcription of Ccr2 1 0.24 1 0.09
59 INT226391 Positive_regulation of Gene_expression of Socs5 1 0.11 0.81 0.07
60 INT352112 Transcription of CCL19 1 0.38 1.37 0.06
61 INT352100 Positive_regulation of Transcription of CCL19 1 0.37 1.38 0.06
62 INT290329 Positive_regulation of Positive_regulation of CD80 1 0.17 0.44 0.04
63 INT352095 Regulation of Gene_expression of CCL19 1 0.21 0.68 0.03
64 INT352113 Positive_regulation of Positive_regulation of CCL19 1 0.27 1.06 0
65 INT264195 Positive_regulation of Binding of CD80 1 0.31 0.21 0
66 INT166967 Negative_regulation of Ccr7 1 0.09 0 0
67 INT352098 Negative_regulation of Gene_expression of CCL19 1 0.23 1.48 0
68 INT184034 Binding of Socs5 1 0.24 2.05 0
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