GO:0045630

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Name positive regulation of T-helper 2 cell differentiation
Categary Process
Go Slim No
Go Link GO:0045630
Unique Molecular Interactions 938
Total Molecular Interactions 1422
Total Single Events 12835
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of T-helper 2 cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of T-helper 2 cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
2 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
3 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
4 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
5 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
6 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
7 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
8 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
9 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
10 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
11 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
12 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
13 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
14 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
15 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
16 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
17 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
18 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
19 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
20 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
21 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
22 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
23 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
24 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
25 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
26 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
27 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
28 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
29 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
30 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
31 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
32 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
33 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
34 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
35 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
36 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
37 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
38 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
39 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
40 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
41 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
42 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
43 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
44 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
45 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
46 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
47 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
48 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
49 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
50 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
51 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
52 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
53 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
54 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
55 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
56 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
57 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
58 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
59 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
60 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
61 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
62 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
63 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
64 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
65 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
66 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
67 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
68 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
69 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
70 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
71 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
72 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
73 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
74 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
75 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
76 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
77 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
78 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
79 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
80 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
81 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
82 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
83 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
84 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
85 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
86 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
87 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
88 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
89 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
90 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
91 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
92 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
93 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
94 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
95 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
96 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
97 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
98 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
99 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
100 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
101 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
102 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
103 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
104 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
105 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
106 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
107 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
108 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
109 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
110 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
111 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
112 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
113 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
114 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
115 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
116 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
117 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
118 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
119 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
120 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
121 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
122 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
123 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
124 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
125 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
126 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
127 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
128 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
129 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
130 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
131 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
132 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
133 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
134 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
135 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
136 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
137 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
138 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
139 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
140 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
141 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
142 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
143 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
144 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
145 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
146 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
147 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
148 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
149 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
150 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
151 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
152 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
153 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
154 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
155 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64
156 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
157 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63
158 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
159 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
160 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
161 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
162 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
163 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62
164 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 0.00 0.15 0.62
165 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
166 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61
167 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
168 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
169 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
170 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
171 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
172 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
173 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58
174 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
175 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
176 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
177 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
178 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57
179 INT142312 Lalba Negative_regulation of Localization of Il6 1 0.23 0.73 0.57
180 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
181 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
182 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
183 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
184 INT192971 Positive_regulation of Il6 Positive_regulation of Localization of Stat3 1 0.03 0.86 0.56
185 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
186 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
187 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
188 INT231711 GPR174 Regulation of Transcription of IL6 1 0.01 0.96 0.54
189 INT137016 Il6 Positive_regulation of Gene_expression of Acta2 1 0.01 0.75 0.54
190 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53
191 INT261608 Il6 Negative_regulation of Gene_expression of TNF 1 0.03 1.27 0.53
192 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53
193 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53
194 INT50935 Mtr Regulation of Gene_expression of Il6 1 0.00 0 0.53
195 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52
196 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
197 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
198 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
199 INT269057 Il6 Positive_regulation of Crp 1 0.37 1.83 0.51
200 INT348322 Il6 Positive_regulation of Localization of Crp 1 0.06 3.51 0.51

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of T-helper 2 cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of T-helper 2 cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 365 0.81 241.78 105.78
9 INT19511 Localization of Il6 212 0.81 118.17 67.67
10 INT11937 Localization of Il6 228 0.81 139.83 64.39
11 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
12 INT10706 Regulation of Il6 150 0.62 93.23 62.34
13 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
14 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
15 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
16 INT9210 Regulation of IL6 166 0.62 125.61 49.95
17 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
18 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
19 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
20 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
21 INT9655 Regulation of Il6 98 0.62 70.92 31.95
22 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
23 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
24 INT86437 Binding of IL6 154 0.48 121.22 29.3
25 INT51474 Binding of Il6 55 0.48 44.99 20.52
26 INT49985 Transcription of Il6 62 0.72 40.13 20.29
27 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
28 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
29 INT61626 Transcription of IL6 73 0.72 42.04 17.86
30 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
31 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
32 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
33 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
34 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
35 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
36 INT54763 Binding of Il6 82 0.48 63.27 12.89
37 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
38 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
39 INT50933 Transcription of Il6 38 0.72 24.31 11.58
40 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36
41 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
42 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
43 INT19620 Binding of CD86 30 0.47 12.01 9.89
44 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
45 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
46 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
47 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
48 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
49 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
50 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
51 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
52 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
53 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
54 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
55 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
56 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
57 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
58 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
59 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
60 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
61 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
62 INT155486 Positive_regulation of Gene_expression of CD86 16 0.69 14.6 2.86
63 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
64 INT75685 Regulation of CD86 12 0.58 3.55 2.66
65 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
66 INT19621 Positive_regulation of CD86 23 0.69 14 2.58
67 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
68 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
69 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
70 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
71 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
72 INT19617 Negative_regulation of CD86 12 0.42 3.68 1.77
73 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
74 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
75 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
76 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
77 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55
78 INT118149 Positive_regulation of Binding of Prkcz 1 0.09 0.58 1.54
79 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
80 INT67457 Binding of Rara 12 0.24 8.28 1.45
81 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
82 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
83 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
84 INT118150 Positive_regulation of Positive_regulation of Prkcz 1 0.08 0.49 1.42
85 INT81400 Binding of RARA 25 0.36 12.93 1.27
86 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
87 INT182985 Transcription of RARA 9 0.60 3.52 1.12
88 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
89 INT134260 Negative_regulation of Transcription of Il6 2 0.25 1.39 0.99
90 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
91 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
92 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
93 INT192090 Localization of Rara 6 0.46 4.15 0.89
94 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
95 INT167763 Negative_regulation of Prkcz 1 0.04 0.32 0.88
96 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
97 INT209958 Negative_regulation of Binding of CD86 1 0.40 0.28 0.85
98 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
99 INT48250 Regulation of Rara 3 0.29 2.47 0.83
100 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
101 INT109060 Regulation of Gene_expression of PRKCZ 1 0.03 0 0.83
102 INT192851 Phosphorylation of Il6 7 0.68 3.12 0.82
103 INT212109 Localization of RARA 5 0.65 3.17 0.79
104 INT300843 Regulation of Transcription of Il6 3 0.37 3.4 0.76
105 INT52196 Negative_regulation of Regulation of Il6 3 0.42 3.42 0.74
106 INT158354 Negative_regulation of Binding of Il6 2 0.20 2.21 0.71
107 INT91398 Regulation of RARA 7 0.59 5.84 0.67
108 INT261602 Positive_regulation of Binding of Il6 2 0.50 1.75 0.62
109 INT138730 Negative_regulation of Negative_regulation of Il6 3 0.09 1.04 0.61
110 INT155485 Regulation of Gene_expression of CD86 7 0.61 3.73 0.6
111 INT264490 Regulation of Negative_regulation of Il6 2 0.23 1.18 0.6
112 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
113 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56
114 INT61025 Negative_regulation of Negative_regulation of Il6 3 0.43 1.15 0.56
115 INT174797 Regulation of Tnfsf4 1 0.03 4.05 0.54
116 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
117 INT220268 Regulation of Regulation of Il6 2 0.12 0.89 0.49
118 INT115189 Regulation of Phosphorylation of IL6 1 0.04 0 0.48
119 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46
120 INT172800 Binding of Tnfsf4 2 0.04 4.58 0.45
121 INT110477 Positive_regulation of Localization of PRKCZ 1 0.20 0.07 0.45
122 INT98447 Positive_regulation of Negative_regulation of Il6 1 0.44 0.75 0.45
123 INT172801 Positive_regulation of Tnfsf4 4 0.08 7.95 0.44
124 INT110479 Localization of PRKCZ 1 0.35 0.07 0.43
125 INT182966 Regulation of Gene_expression of RARA 2 0.39 0.12 0.42
126 INT211982 Negative_regulation of Binding of Rara 1 0.28 0.24 0.42
127 INT285471 Negative_regulation of Binding of Il6 2 0.21 1.33 0.41
128 INT110478 Regulation of PRKCZ 1 0.20 0.1 0.37
129 INT82552 Negative_regulation of Regulation of Il6 2 0.38 1.43 0.36
130 INT236332 Negative_regulation of Gene_expression of CD86 9 0.42 4.4 0.35
131 INT143536 Protein_catabolism of Il6 2 0.69 1.89 0.31
132 INT174805 Gene_expression of Tnfsf4 1 0.04 3.49 0.28
133 INT194162 Protein_catabolism of Il6 2 0.12 0.79 0.27
134 INT211287 Regulation of Binding of Il6 1 0.06 0.1 0.27
135 INT201071 Positive_regulation of Regulation of Il6 2 0.39 0.45 0.25
136 INT298665 Positive_regulation of Protein_catabolism of IL6 1 0.09 2.03 0.25
137 INT10375 Negative_regulation of Gene_expression of RARA 1 0.57 0.97 0.22
138 INT261747 Gene_expression of Il4ra 1 0.22 0.58 0.21
139 INT261749 Binding of Il4ra 1 0.26 0.51 0.2
140 INT172790 Negative_regulation of Tnfsf4 1 0.05 2.43 0.14
141 INT188222 Positive_regulation of Regulation of IL6 2 0.29 0.51 0.13
142 INT192091 Regulation of Localization of Rara 1 0.04 0.67 0.13
143 INT298669 Negative_regulation of Protein_catabolism of IL6 1 0.08 1.02 0.13
144 INT172785 Positive_regulation of Binding of Tnfsf4 1 0.05 2.89 0.12
145 INT181847 Negative_regulation of Positive_regulation of CD86 1 0.41 0.98 0.1
146 INT214071 Negative_regulation of Transcription of RARA 3 0.37 1.77 0.07
147 INT182975 Phosphorylation of RARA 2 0.58 0.23 0.07
148 INT352366 Localization of CD86 1 0.74 0.29 0.07
149 INT352365 Positive_regulation of Localization of CD86 1 0.50 0.29 0.07
150 INT253097 Negative_regulation of Phosphorylation of Il6 1 0.35 0.23 0.06
151 INT352367 Positive_regulation of Regulation of CD86 1 0.50 0.06 0.06
152 INT174802 Positive_regulation of Regulation of Tnfsf4 1 0.03 0.92 0.06
153 INT174799 Regulation of Binding of Tnfsf4 1 0.03 0.92 0.04
154 INT264199 Positive_regulation of Binding of CD86 2 0.25 0.82 0.03
155 INT337245 Positive_regulation of Positive_regulation of CD86 1 0.22 0.62 0.03
156 INT182990 Positive_regulation of Gene_expression of RARA 5 0.40 3.45 0
157 INT182965 Positive_regulation of Phosphorylation of RARA 1 0.29 0 0
158 INT335229 Regulation of Transcription of RARA 1 0.15 0.95 0
159 INT19618 Regulation of Binding of CD86 1 0.00 0.09 0
160 INT337202 Transcription of CD86 1 0.30 0.62 0
161 INT183002 Positive_regulation of Binding of RARA 1 0.29 1.08 0
162 INT335226 Negative_regulation of Negative_regulation of RARA 1 0.24 0.71 0
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