GO:0045638

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Name negative regulation of myeloid cell differentiation
Categary Process
Go Slim No
Go Link GO:0045638
Unique Molecular Interactions 97
Total Molecular Interactions 111
Total Single Events 842
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of myeloid cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of myeloid cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131257 ITIH4 Positive_regulation of Gene_expression of Nfkbia 1 0.23 1.41 2.3
2 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66
3 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
4 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
5 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
6 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
7 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
8 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87
9 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86
10 INT151882 Binding of YY1 and DLL1 1 0.00 0 0.79
11 INT151883 Negative_regulation of Binding of YY1 and DLL1 1 0.00 0 0.79
12 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
13 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
14 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
15 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
16 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
17 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
18 INT233669 gr Positive_regulation of Transcription of Nfkbia 1 0.26 0.33 0.64
19 INT148379 UFM1 Positive_regulation of DLL1 1 0.00 1.13 0.63
20 INT86644 Binding of OPRD1 and DLL1 1 0.28 0.17 0.58
21 INT149652 Zfp36 Regulation of Nos2 1 0.09 0.42 0.47
22 INT87934 Phosphorylation of Nfkbia Positive_regulation of Nfkb1 1 0.02 0.1 0.45
23 INT87936 Nfkbia Positive_regulation of Nfkb1 1 0.03 0.1 0.44
24 INT99122 Binding of Cacna2d3 and DLL1 1 0.02 0 0.41
25 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4
26 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
27 INT108879 Negative_regulation of PTGS2 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.43 0.31
28 INT143724 Binding of Ikbkg and Nfkbia 1 0.02 0.79 0.29
29 INT143723 Positive_regulation of Binding of Ikbkg and Nfkbia 1 0.02 0.8 0.29
30 INT80873 Positive_regulation of Nfkb1 Positive_regulation of Protein_catabolism of Nfkbia 2 0.01 0.58 0.27
31 INT108878 ZNF236 Regulation of Protein_catabolism of Nfkbia 1 0.00 0.38 0.26
32 INT108880 ZNF236 Regulation of Gene_expression of Nfkbia 1 0.00 0.38 0.26
33 INT108877 ZNF236 Regulation of Phosphorylation of Nfkbia 1 0.00 0.38 0.26
34 INT108881 ZNF236 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.26
35 INT144241 CGA Negative_regulation of Phosphorylation of NFKBIA 1 0.10 0.34 0.22
36 INT144244 TNF Positive_regulation of Protein_catabolism of NFKBIA 1 0.28 0.34 0.22
37 INT144253 TNF Positive_regulation of Phosphorylation of NFKBIA 1 0.39 0.34 0.22
38 INT144247 CGA Positive_regulation of Protein_catabolism of NFKBIA 1 0.11 0.34 0.22
39 INT144243 CGA Positive_regulation of Phosphorylation of NFKBIA 1 0.11 0.34 0.22
40 INT319311 Binding of Glud1 and Ptk2b 1 0.36 0 0.19
41 INT159788 Tnf Positive_regulation of Phosphorylation of Nfkbia 1 0.01 0.39 0.19
42 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
43 INT136606 Binding of RAN and DLL1 1 0.33 0.45 0.15
44 INT319314 Binding of Ptk2b and Rbm39 1 0.01 0.08 0.14
45 INT319316 Binding of GRIN1 and Ptk2b 1 0.52 0.08 0.14
46 INT139790 PRSS53 Negative_regulation of Phosphorylation of NFKBIA 1 0.01 0.9 0.11
47 INT306265 Binding of NFKB1 and NFKBIA 1 0.21 0.48 0.11
48 INT139789 TNFAIP8 Positive_regulation of Phosphorylation of NFKBIA 1 0.02 0.89 0.11
49 INT139788 TNFAIP8 Positive_regulation of NFKBIA 1 0.01 0.88 0.11
50 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
51 INT263449 Binding of NFKBIA and TBK1 1 0.07 0.2 0.1
52 INT263450 NFKB2 Positive_regulation of Protein_catabolism of NFKBIA 1 0.17 0.17 0.09
53 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
54 INT355604 VEGFA Regulation of Positive_regulation of Ptk2b 1 0.22 1.47 0.08
55 INT118416 Gata2 Positive_regulation of Transcription of Tac2 1 0.27 0.2 0.07
56 INT319309 Egr2 Regulation of Ptk2b 1 0.29 0.37 0.07
57 INT333256 Gene_expression of Cxcl12 Negative_regulation of Ptk2b 1 0.10 0.99 0.07
58 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05
59 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
60 INT161532 Tlr4 Positive_regulation of Protein_catabolism of Nfkbia 1 0.00 0.76 0.03
61 INT161531 Nfkbia Regulation of Gene_expression of Tlr4 1 0.01 0.75 0.03
62 INT260946 Zfp36 Negative_regulation of Binding of Elavl1 1 0.21 0.11 0.03
63 INT161534 Tlr4 Positive_regulation of Phosphorylation of Nfkbia 1 0.00 0.77 0.03
64 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
65 INT215766 Dio1 Regulation of Cdk6 1 0.01 0.05 0
66 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0
67 INT215706 Binding of Cdk6 and Lamtor1 1 0.04 0 0
68 INT225229 Binding of Cdk6 and Cdkn2a 1 0.19 1.25 0
69 INT273886 Binding of Dll1 and Trip12 1 0.34 0.1 0
70 INT215700 Binding of Cdkn2b and Cdk6 1 0.02 0 0
71 INT215690 Binding of Cdk6 and Cdkn1c 1 0.03 0 0
72 INT185280 Binding of CDK4 and CDK6 1 0.20 0.87 0
73 INT215682 Binding of Cdkn1b and Cdk6 1 0.03 0 0
74 INT215701 Slc3a1 Regulation of Cdk6 1 0.01 0.05 0
75 INT326728 Sox10 Regulation of Twist2 1 0.45 0.05 0
76 INT204077 Binding of CDKN2A and Cdk6 1 0.15 0.72 0
77 INT164909 IL33 Positive_regulation of Phosphorylation of NFKBIA 1 0.53 0.05 0
78 INT215703 Binding of Kras and Cdk6 1 0.01 0 0
79 INT285641 Zfp36 Negative_regulation of Egr1 1 0.06 0.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of myeloid cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of myeloid cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
2 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
3 INT81538 Phosphorylation of Nfkbia 27 0.62 8.86 10.49
4 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98
5 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
6 INT80872 Protein_catabolism of Nfkbia 28 0.92 10.56 8.62
7 INT95297 Gene_expression of Nfkbia 14 0.68 7.61 8.24
8 INT55859 Binding of Dll1 6 0.35 0 7.64
9 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 21 0.54 8.92 7.38
10 INT93481 Negative_regulation of Protein_catabolism of Nfkbia 14 0.39 7.24 7.21
11 INT88498 Protein_catabolism of Nfkbia 14 0.82 6.94 7.1
12 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
13 INT81541 Negative_regulation of Nfkbia 12 0.51 5.73 6.79
14 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
15 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
16 INT81535 Negative_regulation of Phosphorylation of Nfkbia 15 0.44 5.74 5.18
17 INT143234 Gene_expression of Nfkbia 10 0.62 5.2 5.02
18 INT88496 Positive_regulation of Protein_catabolism of Nfkbia 8 0.53 3.05 4.78
19 INT131253 Positive_regulation of Gene_expression of Nfkbia 4 0.41 3.28 4.71
20 INT71406 Regulation of Dll1 3 0.35 0.79 4.44
21 INT87210 Positive_regulation of Nfkbia 9 0.61 3.89 4.35
22 INT10542 Gene_expression of DLL1 16 0.71 3.7 4.21
23 INT81543 Positive_regulation of Phosphorylation of Nfkbia 7 0.37 2.51 4.1
24 INT108868 Transcription of Nfkbia 2 0.57 2.91 4.03
25 INT40036 Binding of DLL1 10 0.36 2.88 3.95
26 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84
27 INT49190 Regulation of Dll1 3 0.44 0.26 3.24
28 INT55148 Binding of Dll1 5 0.48 0.66 2.97
29 INT66891 Negative_regulation of Positive_regulation of Dll1 1 0.41 0 2.72
30 INT233606 Transcription of Nfkbia 1 0.66 1.55 2.71
31 INT93401 Positive_regulation of Protein_catabolism of Nfkbia 11 0.46 3.89 2.7
32 INT107968 Positive_regulation of NFKBIA 9 0.46 5.27 2.69
33 INT47974 Negative_regulation of Protein_catabolism of NFKBIA 7 0.49 2.38 2.69
34 INT108869 Localization of Nfkbia 5 0.56 1.04 2.63
35 INT67329 Positive_regulation of Positive_regulation of Dll1 2 0.32 0 2.56
36 INT122003 Phosphorylation of NFKBIA 9 0.59 5.44 2.51
37 INT132315 Positive_regulation of DLL1 6 0.67 3.4 2.45
38 INT129318 Negative_regulation of NFKBIA 10 0.38 6.19 2.02
39 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01
40 INT26317 Gene_expression of NFKBIA 5 0.45 2.97 1.96
41 INT56080 Transcription of NFKBIA 2 0.40 2.16 1.93
42 INT151269 Positive_regulation of Localization of Nfkbia 1 0.37 0 1.86
43 INT159099 Negative_regulation of Positive_regulation of Dll1 1 0.25 0.74 1.76
44 INT159100 Regulation of Positive_regulation of Dll1 1 0.26 0.7 1.73
45 INT126236 Positive_regulation of Positive_regulation of NFKBIA 4 0.46 2.18 1.69
46 INT159098 Negative_regulation of Gene_expression of Dll1 1 0.18 0.62 1.65
47 INT52757 Localization of Dll1 1 0.20 0 1.6
48 INT47972 Positive_regulation of Protein_catabolism of NFKBIA 5 0.46 2.09 1.53
49 INT105296 Regulation of DLL1 3 0.11 0.77 1.43
50 INT233612 Regulation of Transcription of Nfkbia 1 0.36 0.55 1.43
51 INT87215 Localization of Nfkbia 5 0.69 1.64 1.39
52 INT233638 Positive_regulation of Transcription of Nfkbia 1 0.56 1.01 1.33
53 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
54 INT131254 Positive_regulation of Transcription of Nfkbia 1 0.36 0.99 1.28
55 INT319293 Phosphorylation of Ptk2b 9 0.80 3.14 1.24
56 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22
57 INT166013 Positive_regulation of Gene_expression of NFKBIA 2 0.32 1.15 1.2
58 INT129726 Regulation of Nfkbia 2 0.06 1.63 1.05
59 INT107971 Regulation of NFKBIA 3 0.24 2.03 1.04
60 INT81542 Regulation of Protein_catabolism of Nfkbia 2 0.04 0.43 1.02
61 INT99121 Transcription of DLL1 1 0.14 0 1.02
62 INT290411 Gene_expression of Ptk2b 10 0.65 3.72 1.01
63 INT143235 Positive_regulation of Gene_expression of Nfkbia 2 0.56 0.97 1.01
64 INT181367 Negative_regulation of Ccl21b 1 0.01 1.72 0.98
65 INT124198 Negative_regulation of Nfkbia 4 0.37 2.58 0.97
66 INT250699 Binding of CDK6 3 0.33 2.54 0.97
67 INT236927 Positive_regulation of Ptk2b 9 0.67 3.41 0.94
68 INT81540 Positive_regulation of Nfkbia 4 0.22 1.37 0.92
69 INT143714 Phosphorylation of Nfkbia 4 0.64 2.94 0.87
70 INT243611 Gene_expression of Twist2 5 0.67 2.85 0.86
71 INT143720 Negative_regulation of Phosphorylation of Nfkbia 3 0.33 2.68 0.83
72 INT159548 Regulation of Protein_catabolism of Nfkbia 1 0.18 0.62 0.82
73 INT99120 Positive_regulation of Transcription of DLL1 1 0.10 0 0.77
74 INT233630 Regulation of Nfkbia 1 0.42 0.27 0.76
75 INT233646 Regulation of Localization of Nfkbia 1 0.42 0.27 0.76
76 INT95298 Negative_regulation of Gene_expression of Nfkbia 2 0.38 0.62 0.71
77 INT81533 Negative_regulation of Negative_regulation of Nfkbia 1 0.04 0.36 0.7
78 INT139089 Negative_regulation of Gene_expression of Dll1 2 0.43 0 0.69
79 INT181366 Regulation of Ccl21b 1 0.01 0.52 0.69
80 INT143719 Negative_regulation of Gene_expression of Nfkbia 2 0.43 1.31 0.68
81 INT166019 Regulation of Gene_expression of NFKBIA 1 0.05 0.64 0.65
82 INT122004 Negative_regulation of Phosphorylation of NFKBIA 3 0.41 1.59 0.58
83 INT263482 Positive_regulation of Transcription of NFKBIA 1 0.39 0.61 0.57
84 INT25362 Binding of NFKBIA 4 0.26 2.52 0.55
85 INT149643 Binding of Zfp36 2 0.29 0.45 0.49
86 INT319254 Localization of Ptk2b 1 0.78 0.26 0.46
87 INT319284 Binding of Ptk2b 1 0.36 0.9 0.45
88 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
89 INT204827 Positive_regulation of Zfp36 1 0.26 0.33 0.43
90 INT319286 Transcription of Ptk2b 1 0.52 1.17 0.4
91 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
92 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
93 INT319276 Positive_regulation of Phosphorylation of Ptk2b 1 0.49 0.62 0.32
94 INT132627 Binding of Nfkbia 1 0.03 0.41 0.31
95 INT10543 Negative_regulation of DLL1 3 0.14 0.67 0.3
96 INT126059 Positive_regulation of Gata2 1 0.02 0.87 0.28
97 INT56079 Negative_regulation of Transcription of NFKBIA 1 0.05 0.54 0.26
98 INT108867 Regulation of Transcription of Nfkbia 1 0.00 0.36 0.25
99 INT244742 Gene_expression of Gata2 2 0.54 0.18 0.23
100 INT353967 Positive_regulation of Gene_expression of Gata2 1 0.42 0.18 0.23
101 INT243604 Localization of Twist2 1 0.65 0.54 0.2
102 INT243599 Positive_regulation of Localization of Twist2 1 0.43 0.54 0.2
103 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
104 INT226422 Negative_regulation of Cdk6 3 0.12 1.83 0.19
105 INT151129 Negative_regulation of Localization of Nfkbia 1 0.30 0.31 0.19
106 INT319247 Regulation of Ptk2b 1 0.60 0 0.18
107 INT327283 Negative_regulation of Zfp36 1 0.39 0.5 0.18
108 INT154558 Regulation of Phosphorylation of Nfkbia 1 0.00 0.33 0.17
109 INT87209 Negative_regulation of Positive_regulation of Nfkbia 1 0.31 0.15 0.16
110 INT87213 Positive_regulation of Localization of Nfkbia 1 0.34 0.15 0.16
111 INT136609 Positive_regulation of Binding of DLL1 1 0.49 0.45 0.15
112 INT136922 Positive_regulation of Gene_expression of DLL1 2 0.46 1.28 0.13
113 INT136919 Negative_regulation of Gene_expression of DLL1 1 0.54 0.3 0.13
114 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
115 INT139798 Positive_regulation of Phosphorylation of NFKBIA 1 0.04 0.88 0.11
116 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
117 INT260907 Phosphorylation of Zfp36 1 0.54 0.47 0.08
118 INT271084 Negative_regulation of Gene_expression of Cdk6 1 0.11 1.1 0.06
119 INT271086 Gene_expression of Cdk6 1 0.14 1.09 0.06
120 INT260911 Regulation of Phosphorylation of Zfp36 1 0.30 0.23 0.04
121 INT204060 Gene_expression of Cdk6 3 0.26 0.83 0
122 INT200683 Gene_expression of PTK2B 2 0.67 1.02 0
123 INT325167 Gene_expression of CDK6 2 0.43 0 0
124 INT260926 Regulation of Zfp36 2 0.21 0.47 0
125 INT243389 Transcription of PTK2B 1 0.64 0.52 0
126 INT326697 Negative_regulation of Twist2 1 0.35 0.23 0
127 INT200665 Negative_regulation of Gene_expression of PTK2B 1 0.04 0.69 0
128 INT333821 Regulation of Cdk6 1 0.23 0 0
129 INT149645 Positive_regulation of Gene_expression of Zfp36 1 0.14 0 0
130 INT204061 Negative_regulation of Gene_expression of Cdk6 1 0.12 0.47 0
131 INT302260 Negative_regulation of CDK6 1 0.19 0.29 0
132 INT326721 Regulation of Twist2 1 0.22 0.22 0
133 INT215749 Regulation of Gene_expression of Cdk6 1 0.17 0 0
134 INT325171 Regulation of Gene_expression of CDK6 1 0.25 0 0
135 INT149639 Gene_expression of Zfp36 1 0.22 0 0
136 INT156922 Positive_regulation of Phosphorylation of PTK2B 1 0.23 0 0
137 INT236709 Phosphorylation of Cdk6 1 0.34 0.82 0
138 INT290418 Regulation of Gene_expression of Ptk2b 1 0.17 0.1 0
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