GO:0045639

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Name positive regulation of myeloid cell differentiation
Categary Process
Go Slim No
Go Link GO:0045639
Unique Molecular Interactions 350
Total Molecular Interactions 554
Total Single Events 3351
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of myeloid cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of myeloid cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
2 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
3 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
4 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
5 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
6 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
7 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
8 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
9 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
10 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
11 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
12 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
13 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
14 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
15 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
16 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
17 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
18 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
19 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
20 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
21 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
22 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
23 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
24 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
25 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
26 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
27 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
28 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
29 INT349083 Binding of Lep and Rtn1 1 0.09 1.68 0.57
30 INT91339 Binding of Lep and Cck 1 0.28 0.34 0.56
31 INT113162 Lep Positive_regulation of Positive_regulation of Insrr 1 0.03 0 0.55
32 INT253834 Cck Regulation of Lep 1 0.19 0.23 0.55
33 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
34 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
35 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
36 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53
37 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53
38 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
39 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
40 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
41 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
42 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
43 INT132509 Binding of LEP and Cck 1 0.13 0.16 0.45
44 INT323880 Binding of BMI1 and LEP 1 0.02 3.97 0.41
45 INT83171 Cck Regulation of Lep 1 0.30 0.09 0.4
46 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4
47 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
48 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37
49 INT300488 Binding of CRP and LEP 1 0.46 2.03 0.37
50 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
51 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
52 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
53 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
54 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
55 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36
56 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
57 INT278949 JAK3 Positive_regulation of Gene_expression of LEP 1 0.42 0.63 0.36
58 INT323885 LEP Regulation of Gene_expression of NOS2 1 0.26 1.07 0.35
59 INT213484 Binding of Lep and Pik3c3 1 0.01 0 0.35
60 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33
61 INT323870 LEP Regulation of Gene_expression of MMP13 1 0.21 1.76 0.33
62 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33
63 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
64 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
65 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
66 INT278939 LEP Regulation of IL8 1 0.13 0.61 0.31
67 INT213485 Lep Positive_regulation of Localization of Grin2a 1 0.19 0 0.31
68 INT278969 LEP Regulation of PTGER2 1 0.03 0.6 0.31
69 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
70 INT226989 Lias Regulation of Gene_expression of Lep 1 0.10 0.91 0.3
71 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
72 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29
73 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29
74 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29
75 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29
76 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
77 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28
78 INT100531 Cck Positive_regulation of Lep 1 0.70 0.15 0.26
79 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
80 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
81 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
82 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25
83 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
84 INT125748 Binding of LEP and Gh 1 0.00 0.52 0.24
85 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24
86 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24
87 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
88 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24
89 INT253773 TNF Positive_regulation of Hmgb1 1 0.09 1.21 0.23
90 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23
91 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23
92 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23
93 INT323883 BMI1 Regulation of LEP 1 0.02 2.39 0.23
94 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22
95 INT102937 Gnrh1 Positive_regulation of Gene_expression of Lep 1 0.50 0 0.22
96 INT110653 Lep Regulation of Localization of Cck 1 0.06 0.22 0.22
97 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21
98 INT323873 LEP Regulation of Gene_expression of TIMP2 1 0.31 0.63 0.21
99 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21
100 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2
101 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2
102 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2
103 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2
104 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2
105 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2
106 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2
107 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2
108 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2
109 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2
110 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
111 INT256576 Lep Regulation of Localization of Ins1 1 0.57 2.08 0.2
112 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2
113 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19
114 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19
115 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19
116 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19
117 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19
118 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
119 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19
120 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
121 INT323613 Il1 Regulation of Localization of Hmgb1 1 0.10 0.75 0.19
122 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18
123 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18
124 INT226988 Lias Positive_regulation of Localization of Lep 1 0.08 0.3 0.17
125 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17
126 INT344832 Hmgb1 Positive_regulation of Gene_expression of Nos2 1 0.12 0.82 0.17
127 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16
128 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16
129 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16
130 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15
131 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14
132 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14
133 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14
134 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14
135 INT323877 LEP Positive_regulation of SOAT1 1 0.20 1.26 0.14
136 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
137 INT343920 Binding of TLR4 and Hmgb1 1 0.39 0.97 0.13
138 INT324866 Hmgb1 Positive_regulation of Tlr4 1 0.16 1.29 0.13
139 INT139975 Binding of LEP and Prl 1 0.02 0.49 0.13
140 INT343917 Binding of IRF6 and Hmgb1 1 0.05 0.98 0.13
141 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
142 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13
143 INT346714 LEP Regulation of GALP 1 0.06 0.08 0.13
144 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12
145 INT81179 LEP Regulation of Localization of GH1 1 0.11 0.91 0.12
146 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.73 0.12
147 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12
148 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12
149 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
150 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12
151 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12
152 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 0.06 0.69 0.12
153 INT164746 Binding of LEP and Adipoq 1 0.07 0.69 0.12
154 INT323871 LEP Regulation of Gene_expression of IGF1 1 0.14 1.19 0.11
155 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11
156 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11
157 INT163817 Lep Positive_regulation of Phosphorylation of Akt1 1 0.33 0.31 0.11
158 INT222472 Lep Positive_regulation of Localization of Cartpt 1 0.05 0 0.11
159 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
160 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
161 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1
162 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
163 INT323879 LEP Regulation of SOAT1 1 0.15 1.15 0.1
164 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1
165 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1
166 INT123864 Lep Positive_regulation of Positive_regulation of Cck 1 0.45 0.1 0.09
167 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09
168 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09
169 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09
170 INT215095 Negative_regulation of Il6 Positive_regulation of Hmgb1 1 0.13 1.03 0.09
171 INT213482 Lep Positive_regulation of Mapk1 1 0.06 0.08 0.09
172 INT300486 LEP Positive_regulation of ROS1 1 0.15 0.91 0.09
173 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
174 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 0.08 0.92 0.09
175 INT222545 Lep Negative_regulation of Nmb 1 0.04 0.52 0.08
176 INT123866 Lep Negative_regulation of Olfr544 1 0.00 0.09 0.08
177 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08
178 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08
179 INT323881 BMI1 Regulation of Gene_expression of LEP 1 0.03 1.09 0.08
180 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
181 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08
182 INT268325 Lep Positive_regulation of Ptgs2 1 0.09 0.39 0.08
183 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08
184 INT294743 Lep Positive_regulation of Transcription of Il6 1 0.18 0.42 0.07
185 INT294740 Lep Positive_regulation of Transcription of Ccl2 1 0.08 0.42 0.07
186 INT323872 LEP Positive_regulation of Gene_expression of IGF1 1 0.35 0.77 0.07
187 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07
188 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
189 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
190 INT214153 Lep Regulation of Transcription of Nucb2 1 0.35 0.15 0.06
191 INT253377 Lep Negative_regulation of Phosphorylation of Prkaa2 1 0.24 1.24 0.06
192 INT258290 Hmgb1 Regulation of Positive_regulation of Tlr2 1 0.46 1.04 0.05
193 INT323878 Binding of LEP and MMP13 1 0.17 0.77 0.05
194 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05
195 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05
196 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05
197 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05
198 INT314135 Negative_regulation of Nos2 Positive_regulation of Lep 1 0.52 0.44 0.05
199 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05
200 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of myeloid cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of myeloid cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
2 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
3 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
4 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
5 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
6 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
7 INT75908 Regulation of LEP 77 0.60 60.16 15.19
8 INT73641 Regulation of Lep 45 0.62 26.2 12.59
9 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
10 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
11 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
12 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
13 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
14 INT82082 Localization of Lep 63 0.81 26.41 8.56
15 INT75907 Binding of LEP 53 0.46 46.65 8.44
16 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
17 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
18 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
19 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
20 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
21 INT65356 Localization of LEP 46 0.79 41.17 5.43
22 INT91338 Binding of Lep 31 0.48 26.86 5.39
23 INT102935 Regulation of Lep 31 0.60 18.47 5.24
24 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55
25 INT97391 Binding of Lep 18 0.48 8.97 4.47
26 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
27 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
28 INT163581 Localization of Lep 27 0.79 18.99 4.08
29 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
30 INT184288 Localization of HMGB1 20 0.61 14.5 3.84
31 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
32 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
33 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
34 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
35 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
36 INT184272 Binding of HMGB1 14 0.37 8.78 2.49
37 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
38 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
39 INT83392 Transcription of Lep 6 0.54 5.07 2.04
40 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
41 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
42 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
43 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58
44 INT184271 Positive_regulation of Gene_expression of HMGB1 7 0.41 6.17 1.53
45 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
46 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
47 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
48 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
49 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
50 INT219168 Positive_regulation of Localization of HMGB1 5 0.36 4 1.16
51 INT213465 Transcription of Lep 4 0.68 2.11 1.15
52 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
53 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
54 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
55 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
56 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
57 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
58 INT221543 Binding of Fes 1 0.45 1.79 0.83
59 INT303347 Positive_regulation of Gene_expression of Jag1 6 0.65 4.06 0.77
60 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
61 INT82080 Regulation of Localization of Lep 2 0.45 1.36 0.76
62 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
63 INT156533 Transcription of LEP 9 0.69 4.35 0.74
64 INT213471 Positive_regulation of Localization of Lep 4 0.48 2.65 0.74
65 INT74781 Regulation of JAG1 6 0.39 2.75 0.63
66 INT148382 Positive_regulation of JAG1 5 0.23 3.88 0.63
67 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61
68 INT345957 Positive_regulation of Binding of Lep 2 0.38 2.03 0.6
69 INT83391 Negative_regulation of Transcription of Lep 1 0.43 0.34 0.6
70 INT151401 Localization of JAG1 4 0.65 1.88 0.58
71 INT184277 Regulation of Localization of HMGB1 1 0.37 1.15 0.58
72 INT306798 Protein_catabolism of LEP 1 0.65 2.45 0.58
73 INT343799 Negative_regulation of Transcription of HMGB1 1 0.32 0.37 0.5
74 INT215070 Regulation of Localization of Hmgb1 4 0.26 2.23 0.49
75 INT220339 Transcription of HMGB1 2 0.53 2.03 0.49
76 INT82819 Negative_regulation of Negative_regulation of LEP 3 0.56 2.22 0.46
77 INT219178 Negative_regulation of Localization of HMGB1 1 0.22 1.26 0.45
78 INT102934 Positive_regulation of Regulation of Lep 2 0.50 0.55 0.42
79 INT352592 Positive_regulation of Negative_regulation of Hmgb1 1 0.44 1.31 0.42
80 INT323765 Negative_regulation of Binding of Lep 1 0.37 0.91 0.42
81 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41
82 INT151400 Binding of JAG1 14 0.37 7.96 0.39
83 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31
84 INT213467 Negative_regulation of Localization of Lep 2 0.40 1.11 0.31
85 INT258283 Positive_regulation of Positive_regulation of Hmgb1 3 0.44 3.1 0.3
86 INT156534 Positive_regulation of Transcription of LEP 1 0.14 0.34 0.3
87 INT331591 Transcription of Hmgb1 1 0.28 0.92 0.3
88 INT141781 Positive_regulation of Negative_regulation of LEP 1 0.46 0.37 0.29
89 INT273867 Binding of Jag1 18 0.45 3.14 0.25
90 INT150977 Regulation of Regulation of LEP 3 0.37 2.07 0.23
91 INT303374 Negative_regulation of Jag1 2 0.48 0.9 0.23
92 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22
93 INT220336 Negative_regulation of HMGB1 3 0.43 0.97 0.21
94 INT266367 Positive_regulation of Binding of HMGB1 1 0.26 0.31 0.21
95 INT221535 Regulation of Fes 1 0.25 0.19 0.19
96 INT266364 Protein_catabolism of HMGB1 1 0.34 0.29 0.19
97 INT221549 Localization of Fes 1 0.70 0.66 0.19
98 INT221532 Positive_regulation of Fes 1 0.47 0.59 0.19
99 INT163816 Phosphorylation of Lep 2 0.63 2.2 0.17
100 INT333880 Protein_catabolism of Lep 1 0.65 0.34 0.17
101 INT266353 Negative_regulation of Binding of HMGB1 1 0.22 0.22 0.17
102 INT157134 Regulation of Localization of LEP 1 0.09 0.5 0.16
103 INT333882 Regulation of Binding of Lep 1 0.45 0.07 0.16
104 INT204088 Regulation of Negative_regulation of LEP 1 0.59 1.16 0.16
105 INT300489 Negative_regulation of Binding of LEP 1 0.41 1.12 0.15
106 INT258272 Negative_regulation of Binding of Hmgb1 1 0.53 1.82 0.15
107 INT278979 Negative_regulation of Positive_regulation of LEP 2 0.40 0.81 0.14
108 INT344828 Protein_catabolism of Hmgb1 1 0.48 0.67 0.14
109 INT344810 Positive_regulation of Protein_catabolism of Hmgb1 1 0.27 0.67 0.14
110 INT187723 Regulation of Positive_regulation of LEP 3 0.42 2.29 0.13
111 INT323898 Regulation of Phosphorylation of LEP 1 0.42 1.25 0.13
112 INT323895 Phosphorylation of LEP 1 0.76 1.23 0.13
113 INT157241 Negative_regulation of Localization of LEP 5 0.56 2.1 0.12
114 INT221571 Negative_regulation of Fes 1 0.55 0.56 0.12
115 INT163815 Negative_regulation of Negative_regulation of Lep 1 0.43 0.32 0.12
116 INT221577 Negative_regulation of Phosphorylation of Fes 1 0.40 0.37 0.12
117 INT226984 Regulation of Transcription of Lep 1 0.27 0.3 0.11
118 INT318343 Regulation of Binding of Hmgb1 1 0.11 0.41 0.1
119 INT206737 Negative_regulation of Gene_expression of HMGB1 3 0.32 3.48 0.09
120 INT187729 Positive_regulation of Binding of LEP 1 0.18 0.3 0.08
121 INT221530 Negative_regulation of Binding of Fes 1 0.40 0.17 0.08
122 INT213475 Negative_regulation of Positive_regulation of Lep 2 0.40 1.79 0.07
123 INT213466 Negative_regulation of Regulation of Lep 1 0.41 0 0.06
124 INT219231 Positive_regulation of Gene_expression of JAG1 1 0.40 1.18 0.05
125 INT299469 Regulation of HMGB1 2 0.18 2.27 0.03
126 INT221565 Regulation of Binding of Fes 1 0.42 0.05 0.03
127 INT266358 Regulation of Binding of HMGB1 1 0.14 0 0.03
128 INT303349 Positive_regulation of Jag1 5 0.57 1.23 0
129 INT253406 Negative_regulation of Positive_regulation of Lep 2 0.41 0.74 0
130 INT298673 Gene_expression of HOXA5 2 0.49 2.33 0
131 INT286388 Transcription of Jag1 2 0.65 0.64 0
132 INT299470 Regulation of Gene_expression of HMGB1 1 0.18 1.58 0
133 INT150408 Regulation of Regulation of Lep 1 0.27 0 0
134 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0
135 INT305239 Positive_regulation of Phosphorylation of Lep 1 0.43 1.09 0
136 INT320543 Positive_regulation of Gene_expression of HOXA5 1 0.44 0.57 0
137 INT221567 Transcription of Fes 1 0.64 0 0
138 INT303366 Negative_regulation of Gene_expression of Jag1 1 0.55 0.48 0
139 INT332954 Regulation of Transcription of Lep 1 0.11 1.4 0
140 INT157243 Negative_regulation of Transcription of LEP 1 0.02 0.09 0
141 INT221563 Positive_regulation of Localization of Fes 1 0.47 0.05 0
142 INT303370 Protein_catabolism of Jag1 1 0.62 0.05 0
143 INT257560 Regulation of Negative_regulation of JAG1 1 0.13 0.48 0
144 INT303356 Localization of Jag1 1 0.70 0.09 0
145 INT303348 Positive_regulation of Transcription of Jag1 1 0.44 0.64 0
146 INT174279 Positive_regulation of Negative_regulation of Lep 1 0.46 0.16 0
147 INT303353 Negative_regulation of Binding of Jag1 1 0.40 0 0
148 INT221524 Regulation of Localization of Fes 1 0.42 0.06 0
149 INT309421 Positive_regulation of Regulation of Lep 1 0.41 0.61 0
150 INT221523 Negative_regulation of Gene_expression of Fes 1 0.40 0 0
151 INT320550 Transcription of HOXA5 1 0.43 0 0
152 INT303367 Negative_regulation of Positive_regulation of Jag1 1 0.35 0.28 0
153 INT288213 Positive_regulation of Negative_regulation of Lep 1 0.47 0.06 0
154 INT258279 Positive_regulation of Binding of Hmgb1 1 0.45 0.26 0
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