GO:0045665

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Name negative regulation of neuron differentiation
Categary Process
Go Slim No
Go Link GO:0045665
Unique Molecular Interactions 820
Total Molecular Interactions 1170
Total Single Events 8917
Pain Genes Associated 76

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
2 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
3 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66
4 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
5 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
6 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
7 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
8 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
9 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
10 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
11 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
12 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
13 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
14 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
15 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
16 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
17 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
18 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
19 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
20 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
21 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
22 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
23 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
24 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
25 INT52762 Dll1 Regulation of Drd1a 1 0.10 0 0.89
26 INT153370 LBX1 Positive_regulation of Gene_expression of Slc6a5 1 0.02 0 0.88
27 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
28 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
29 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
30 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
31 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
32 INT151882 Binding of YY1 and DLL1 1 0.00 0 0.79
33 INT151883 Negative_regulation of Binding of YY1 and DLL1 1 0.00 0 0.79
34 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
35 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
36 INT178576 CNTN2 Positive_regulation of DPYD 1 0.05 2.18 0.76
37 INT178581 CNTN2 Positive_regulation of PTHLH 1 0.24 2.16 0.75
38 INT178577 CNTN2 Positive_regulation of IL2RA 1 0.03 2.16 0.75
39 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
40 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
41 INT98770 Binding of Dll1 and Gt(pU21)50Imeg 1 0.05 0 0.74
42 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
43 INT75399 Regulation of Binding of Dll1 and Oprd1 1 0.08 0 0.74
44 INT98771 Binding of Dll1 and Oprm1 1 0.29 0 0.74
45 INT75398 Binding of Dll1 and Oprd1 1 0.11 0 0.74
46 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
47 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73
48 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
49 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
50 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
51 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
52 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
53 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
54 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
55 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
56 INT171824 Binding of Ncs1 and Aspm 1 0.00 0.07 0.65
57 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
58 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
59 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63
60 INT148379 UFM1 Positive_regulation of DLL1 1 0.00 1.13 0.63
61 INT2700 Binding of App and Cpe 1 0.00 0 0.63
62 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
63 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
64 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
65 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
66 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
67 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
68 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
69 INT86644 Binding of OPRD1 and DLL1 1 0.28 0.17 0.58
70 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
71 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
72 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
73 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
74 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
75 INT155254 Col4a4 Regulation of Rtn4 1 0.00 0 0.54
76 INT125086 LPA Positive_regulation of Rtn4 1 0.00 0.36 0.54
77 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
78 INT69389 CNTN2 Positive_regulation of PENK 1 0.20 0.53 0.54
79 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
80 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
81 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
82 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
83 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
84 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
85 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
86 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
87 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
88 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
89 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
90 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45
91 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
92 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
93 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
94 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
95 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
96 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
97 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
98 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
99 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
100 INT200327 Oprm1 Negative_regulation of Gene_expression of Rest 1 0.31 0 0.41
101 INT99122 Binding of Cacna2d3 and DLL1 1 0.02 0 0.41
102 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
103 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
104 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
105 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
106 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
107 INT200314 Oprm1 Regulation of Rest 1 0.20 0.1 0.39
108 INT200353 Rest Negative_regulation of Oprm1 1 0.31 0.1 0.39
109 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
110 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
111 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
112 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
113 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
114 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
115 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
116 INT200333 Binding of Rest and Sp1 1 0.24 0.07 0.35
117 INT200316 Sp1 Regulation of Gene_expression of Rest 1 0.31 0 0.35
118 INT200352 Binding of Rest and Rcor2 1 0.16 0.44 0.34
119 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
120 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
121 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
122 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
123 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
124 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
125 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
126 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
127 INT69362 Binding of Pnoc and Rtn4 1 0.01 0 0.31
128 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
129 INT200351 Sp1 Positive_regulation of Gene_expression of Rest 1 0.34 0.07 0.3
130 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
131 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
132 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
133 INT56250 Binding of NBN and NCOR2 1 0.00 0 0.3
134 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
135 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
136 INT141545 Binding of Bace1 and Rtn4 1 0.00 0.45 0.27
137 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
138 INT25946 Regulation of Binding of Penk and App 1 0.18 0.19 0.27
139 INT25944 Binding of Penk and App 1 0.15 0.19 0.27
140 INT141550 Binding of Rtn4r and Rtn4 1 0.00 0.46 0.26
141 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
142 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
143 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
144 INT39010 App Negative_regulation of Gene_expression of Gnrh1 1 0.05 0.07 0.26
145 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
146 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
147 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24
148 INT200309 Positive_regulation of Binding of Rest and Sp3 1 0.41 0.88 0.24
149 INT70661 Binding of Hrasls and Nkx2-2 1 0.02 0 0.24
150 INT318980 Binding of CALR and Positive_regulation of Localization of GOPC 1 0.04 0.32 0.24
151 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
152 INT140376 TGM1 Positive_regulation of Rhoa 1 0.01 0 0.24
153 INT97691 Binding of REST and HDAC9 1 0.26 0.09 0.23
154 INT348321 Binding of POMC and ASPM 1 0.02 0.39 0.23
155 INT155158 Agtr2 Regulation of Rtn4 1 0.00 0.1 0.22
156 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
157 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21
158 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
159 INT181765 WISP3 Regulation of Gene_expression of RHOC 1 0.49 1.46 0.21
160 INT163863 Binding of MIB1 and Vim 1 0.02 1.06 0.21
161 INT97694 Ngf Negative_regulation of Gene_expression of REST 1 0.01 0.09 0.21
162 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
163 INT163864 Binding of MIB1 and Ema 1 0.04 1.07 0.21
164 INT69387 Binding of PENK and CNTN2 1 0.14 0.22 0.21
165 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
166 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
167 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
168 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
169 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
170 INT132054 NBN Positive_regulation of NOS1 1 0.00 0.08 0.2
171 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
172 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
173 INT146687 Regulation of Binding of App and Aph1a 1 0.16 0.58 0.19
174 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
175 INT146686 Binding of App and Aph1a 1 0.14 0.58 0.19
176 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
177 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
178 INT69379 CNTN2 Positive_regulation of Gene_expression of PENK 1 0.18 0.19 0.18
179 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18
180 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
181 INT25945 Plat Regulation of App 1 0.15 0.25 0.17
182 INT25947 Plat Regulation of Transcription of App 1 0.15 0.25 0.17
183 INT244848 Lbx1 Negative_regulation of Cdca3 1 0.07 0.09 0.17
184 INT244858 Lbx1 Negative_regulation of C6 1 0.28 0.09 0.17
185 INT244840 Lbx1 Negative_regulation of C9 1 0.13 0.09 0.16
186 INT244843 Lbx1 Negative_regulation of Hoxd10 1 0.02 0.09 0.16
187 INT244850 Lbx1 Negative_regulation of Hoxd8 1 0.01 0.09 0.16
188 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
189 INT244844 Lbx1 Negative_regulation of Hoxd9 1 0.01 0.09 0.16
190 INT244842 Lbx1 Negative_regulation of Hoxc13 1 0.02 0.09 0.16
191 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
192 INT244845 Lbx1 Negative_regulation of Grcc10 1 0.09 0.09 0.16
193 INT244855 Lbx1 Negative_regulation of Dio1 1 0.03 0.09 0.16
194 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16
195 INT104797 Smarce1 Positive_regulation of REST 1 0.01 0.24 0.15
196 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
197 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
198 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
199 INT201744 Ngf Regulation of Transcription of App 1 0.06 0.39 0.15
200 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of neuron differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of neuron differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
3 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
4 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
5 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
6 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
7 INT5923 Negative_regulation of Rtn4 50 0.36 24.19 27.2
8 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
9 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
10 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
11 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
12 INT11625 Localization of App 98 0.78 55.46 20.86
13 INT16794 Binding of App 103 0.48 64.87 19.79
14 INT65502 Regulation of App 77 0.62 52.05 19.44
15 INT56239 Positive_regulation of Rtn4 20 0.26 14.05 18.8
16 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
17 INT5922 Gene_expression of Rtn4 27 0.48 12.7 17.86
18 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
19 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
20 INT54052 Gene_expression of App 33 0.78 25.08 14.7
21 INT53070 Regulation of Rtn4 15 0.22 9.35 13.77
22 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7
23 INT29745 Binding of APP 47 0.48 26.49 12.4
24 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
25 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
26 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25
27 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
28 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
29 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
30 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
31 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
32 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
33 INT41569 Regulation of APP 32 0.62 17.15 9.4
34 INT56884 Gene_expression of Dll1 9 0.48 1.15 8.98
35 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71
36 INT55859 Binding of Dll1 6 0.35 0 7.64
37 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
38 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
39 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
40 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06
41 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
42 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55
43 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
44 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
45 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
46 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
47 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
48 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
49 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
50 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
51 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
52 INT75546 Transcription of Rtn4 1 0.06 2.87 5.03
53 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
54 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
55 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
56 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
57 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
58 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
59 INT71406 Regulation of Dll1 3 0.35 0.79 4.44
60 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
61 INT69395 Gene_expression of CNTN2 28 0.68 13.29 4.37
62 INT10542 Gene_expression of DLL1 16 0.71 3.7 4.21
63 INT58003 Localization of APP 32 0.80 13.75 4.2
64 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
65 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
66 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
67 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
68 INT40036 Binding of DLL1 10 0.36 2.88 3.95
69 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
70 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
71 INT72179 Negative_regulation of Dll1 5 0.33 4.09 3.84
72 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
73 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
74 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
75 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
76 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
77 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
78 INT62678 Negative_regulation of JAG1 8 0.41 6.95 3.5
79 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49
80 INT233640 Negative_regulation of Olig2 5 0.54 2.02 3.47
81 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
82 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
83 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
84 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
85 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
86 INT49190 Regulation of Dll1 3 0.44 0.26 3.24
87 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
88 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
89 INT156676 Gene_expression of Rtn4 14 0.65 5.78 3.16
90 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
91 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
92 INT55148 Binding of Dll1 5 0.48 0.66 2.97
93 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
94 INT199255 Binding of Rest 14 0.41 1.43 2.94
95 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
96 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
97 INT9242 Negative_regulation of FOXG1 13 0.40 1.43 2.86
98 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
99 INT178772 Transcription of App 17 0.70 10.79 2.79
100 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
101 INT54054 Binding of App 4 0.48 10.89 2.78
102 INT66891 Negative_regulation of Positive_regulation of Dll1 1 0.41 0 2.72
103 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
104 INT67329 Positive_regulation of Positive_regulation of Dll1 2 0.32 0 2.56
105 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
106 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
107 INT132315 Positive_regulation of DLL1 6 0.67 3.4 2.45
108 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
109 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
110 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34
111 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
112 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
113 INT129742 Regulation of Positive_regulation of Rtn4 2 0.05 2.51 2.33
114 INT56030 Regulation of App 8 0.62 4.06 2.32
115 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
116 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
117 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
118 INT171813 Gene_expression of Aspm 1 0.09 0.2 2.18
119 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
120 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
121 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
122 INT132383 Gene_expression of Olig2 16 0.75 5.46 2.07
123 INT39008 Localization of App 13 0.77 9.07 2.05
124 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
125 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
126 INT70526 Binding of CALR 11 0.35 7.09 1.97
127 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
128 INT21941 Regulation of CALR 7 0.53 3.88 1.96
129 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
130 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89
131 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
132 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
133 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
134 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
135 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
136 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
137 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
138 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
139 INT159099 Negative_regulation of Positive_regulation of Dll1 1 0.25 0.74 1.76
140 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
141 INT159100 Regulation of Positive_regulation of Dll1 1 0.26 0.7 1.73
142 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
143 INT159098 Negative_regulation of Gene_expression of Dll1 1 0.18 0.62 1.65
144 INT153635 Positive_regulation of Gene_expression of REST 10 0.54 1.38 1.6
145 INT52757 Localization of Dll1 1 0.20 0 1.6
146 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59
147 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
148 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
149 INT244735 Gene_expression of Ascl1 12 0.58 2.48 1.54
150 INT117033 Gene_expression of JAG1 13 0.65 11.46 1.52
151 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
152 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52
153 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
154 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
155 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
156 INT112845 Negative_regulation of Binding of Nkx2-2 2 0.12 0.14 1.47
157 INT140245 Binding of Gli3 3 0.36 2.65 1.46
158 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
159 INT25943 Transcription of App 5 0.53 1.79 1.44
160 INT105296 Regulation of DLL1 3 0.11 0.77 1.43
161 INT132081 Regulation of Gene_expression of Nkx2-2 2 0.10 0.24 1.43
162 INT235907 Regulation of Negative_regulation of Rtn4 1 0.07 2.93 1.42
163 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
164 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
165 INT165005 Binding of REST 26 0.43 2.81 1.39
166 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
167 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
168 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36
169 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
170 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
171 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
172 INT66118 Binding of Calr 4 0.46 1.46 1.26
173 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
174 INT143759 Gene_expression of SOX2 46 0.55 11.12 1.24
175 INT111859 Regulation of Rhoa 3 0.61 0.23 1.22
176 INT303362 Regulation of Jag1 2 0.22 2.91 1.22
177 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22
178 INT5920 Binding of Rtn4 6 0.36 0.66 1.21
179 INT200838 Positive_regulation of Isl1 6 0.60 0.73 1.19
180 INT110780 Localization of Notch1 2 0.06 0.47 1.19
181 INT169251 Gene_expression of Phox2b 9 0.70 3.88 1.17
182 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
183 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
184 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
185 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
186 INT172809 Gene_expression of ISL1 33 0.40 21.63 1.12
187 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
188 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
189 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
190 INT233237 Gene_expression of Meis1 1 0.77 9.69 1.06
191 INT163963 Negative_regulation of Transcription of Rtn4 1 0.03 0.45 1.06
192 INT67097 Gene_expression of MIB1 20 0.75 21.06 1.03
193 INT49505 Binding of NOTCH3 6 0.47 6.4 1.03
194 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02
195 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
196 INT99121 Transcription of DLL1 1 0.14 0 1.02
197 INT104284 Positive_regulation of Notch3 7 0.50 5.57 0.99
198 INT180423 Positive_regulation of Gene_expression of Rhoa 7 0.40 6.22 0.98
199 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
200 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
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