GO:0045667

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Name regulation of osteoblast differentiation
Categary Process
Go Slim No
Go Link GO:0045667
Unique Molecular Interactions 335
Total Molecular Interactions 409
Total Single Events 2899
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of osteoblast differentiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of osteoblast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
2 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
3 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
4 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
5 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92
6 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
7 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
8 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
9 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
10 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
11 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
12 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
13 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
14 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
15 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
16 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
17 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
18 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
19 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
20 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
21 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
22 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
23 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
24 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
25 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
26 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
27 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
28 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
29 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
30 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
31 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
32 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01
33 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
34 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
35 INT276864 Positive_regulation of Gpr65 Positive_regulation of Prkaca 1 0.16 0.74 0.97
36 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94
37 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94
38 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
39 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92
40 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
41 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89
42 INT196834 Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 2 0.15 0 0.87
43 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 0.22 0.13 0.86
44 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84
45 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
46 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
47 INT78972 Prkaca Regulation of Ina 1 0.11 0.09 0.82
48 INT40610 Binding of Prkaca and Oprl1 1 0.02 0.09 0.8
49 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
50 INT240454 Ephb1 Regulation of Prkaca 1 0.14 0.51 0.79
51 INT91239 Prkaca Regulation of Negative_regulation of Oprm1 1 0.43 0 0.76
52 INT69692 Helt Regulation of Prkaca 1 0.00 0.33 0.76
53 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
54 INT196799 Prkaca Positive_regulation of Phosphorylation of Trh 1 0.02 0 0.74
55 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
56 INT244025 Prkaca Regulation of Phosphorylation of Gabrg1 1 0.08 0.18 0.72
57 INT351350 Prkaca Regulation of Lpar1 1 0.04 0.58 0.72
58 INT148449 Gene_expression of Inhbe Positive_regulation of Prkaca 1 0.05 0.68 0.71
59 INT161297 Ppp1r1b Negative_regulation of Prkaca 1 0.10 0.16 0.7
60 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
61 INT150754 GTS Negative_regulation of Gene_expression of Prkaca 1 0.32 0.08 0.65
62 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
63 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
64 INT104858 Prkaca Negative_regulation of Negative_regulation of TRPV1 2 0.10 0.41 0.64
65 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
66 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
67 INT102863 Prkaca Regulation of Srgn 1 0.50 0.05 0.64
68 INT281081 Prkaca Positive_regulation of Gene_expression of Adcy1 1 0.12 0 0.63
69 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61
70 INT281086 Prkaca Positive_regulation of Mdk 1 0.08 0 0.61
71 INT244055 Prkaca Regulation of Gabrg1 1 0.08 0 0.58
72 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
73 INT356320 ORF61 Positive_regulation of Positive_regulation of Prkaca 1 0.01 0.05 0.57
74 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57
75 INT261485 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Ephb1 1 0.05 0.12 0.56
76 INT103184 Prkaca Positive_regulation of Phosphorylation of CRTC1 1 0.01 0.57 0.55
77 INT296293 Prkaca Regulation of Positive_regulation of Creb1 1 0.16 0.62 0.55
78 INT296291 Prkaca Regulation of Localization of Calm3 1 0.09 0.62 0.55
79 INT296273 Prkaca Regulation of Localization of Camk4 1 0.16 0.62 0.55
80 INT89059 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Trpv1 1 0.07 0.16 0.54
81 INT87559 Vip Positive_regulation of Prkaca 1 0.28 0 0.52
82 INT87557 Crh Positive_regulation of Prkaca 1 0.27 0 0.52
83 INT196830 Arpp21 Regulation of Prkaca 1 0.01 0 0.52
84 INT303720 Prkaca Regulation of Bdkrb1 1 0.02 0.33 0.52
85 INT89058 Prkaca Regulation of Phosphorylation of Trpv1 1 0.04 0.35 0.51
86 INT196824 Ppp1r1b Regulation of Prkaca 1 0.10 0 0.51
87 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51
88 INT87558 Calca Positive_regulation of Prkaca 1 0.35 0 0.51
89 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5
90 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49
91 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
92 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49
93 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49
94 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49
95 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
96 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
97 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
98 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
99 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48
100 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
101 INT296451 Prkaca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
102 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
103 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
104 INT117776 Binding of Ptk2 and Regulation of Phosphorylation of Ddr1 1 0.10 0.17 0.46
105 INT235404 Positive_regulation of RTCA Positive_regulation of Positive_regulation of Prkaca 1 0.00 0.22 0.45
106 INT153994 Regulation of Prkaca Regulation of TRPV1 1 0.02 0.46 0.44
107 INT78975 Positive_regulation of Prkaca Regulation of Ina 1 0.09 0 0.43
108 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
109 INT196821 Phosphorylation of Ppp1r1b Positive_regulation of Prkaca 1 0.09 0 0.41
110 INT78971 Positive_regulation of Prkaca Positive_regulation of Ina 1 0.09 0.09 0.41
111 INT196797 Trh Negative_regulation of Prkaca 1 0.01 0 0.41
112 INT196828 Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.4
113 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38
114 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
115 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
116 INT356284 Ptger2 Positive_regulation of Prkaca 1 0.00 0.39 0.37
117 INT113289 TRPV1 Regulation of Phosphorylation of Prkaca 1 0.02 0.1 0.37
118 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
119 INT235861 Binding of Prkaca and Akap5 1 0.20 0 0.35
120 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
121 INT306692 Prkaca Regulation of Positive_regulation of Nav1 1 0.13 0.06 0.35
122 INT215173 Prkaca Positive_regulation of Positive_regulation of Ptger2 1 0.06 0 0.33
123 INT112917 Nts Negative_regulation of Negative_regulation of Prkaca 1 0.20 0 0.33
124 INT104856 Prkaca Positive_regulation of Phosphorylation of TRPV1 1 0.11 0.23 0.33
125 INT112918 Phospho1 Negative_regulation of Prkaca 1 0.01 0 0.33
126 INT104857 Prkaca Negative_regulation of Localization of TRPV1 1 0.10 0.23 0.33
127 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
128 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
129 INT126852 Prkaca Positive_regulation of Creb1 1 0.27 0.09 0.32
130 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
131 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
132 INT156632 Prkaca Regulation of Scn10a 1 0.13 0.67 0.3
133 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
134 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 0.20 0 0.29
135 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.29
136 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.17 0 0.29
137 INT168513 Prkaca Positive_regulation of Phosphorylation of Trpv1 1 0.22 0.11 0.29
138 INT295360 Ntn1 Positive_regulation of Ptk2 1 0.09 0.51 0.29
139 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
140 INT122312 Prkaca Regulation of Kcnk3 1 0.13 0.28 0.28
141 INT283732 Prkaca Positive_regulation of Creb1 1 0.03 0 0.28
142 INT196695 Prkaca Positive_regulation of CFTR 1 0.46 0.13 0.27
143 INT241969 Grm8 Positive_regulation of Prkaca 1 0.05 0.35 0.27
144 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
145 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
146 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
147 INT241965 Prkaca Negative_regulation of Grm8 1 0.03 0.36 0.26
148 INT149356 Prkaca Negative_regulation of Raf1 1 0.10 0.08 0.25
149 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
150 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
151 INT241970 Acpt Positive_regulation of Positive_regulation of Prkaca 1 0.05 0.36 0.24
152 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
153 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
154 INT71254 MMD Negative_regulation of Prkaca 1 0.00 0 0.24
155 INT356098 Prkca Regulation of Prkaca 1 0.01 0.11 0.24
156 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
157 INT291448 Prkaca Regulation of Gene_expression of Kcnn2 1 0.04 0 0.23
158 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
159 INT291447 Bdnf Positive_regulation of Prkaca 1 0.04 0 0.23
160 INT272753 Positive_regulation of Prkaca Positive_regulation of EGFR 1 0.01 0 0.23
161 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
162 INT276046 Negative_regulation of Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 1 0.15 0.11 0.23
163 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
164 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
165 INT196823 Adcy5 Positive_regulation of Prkaca 1 0.13 0 0.22
166 INT231036 Negative_regulation of Prkaca Negative_regulation of Positive_regulation of Sec22b 1 0.01 0 0.22
167 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
168 INT112920 Nts Positive_regulation of Phosphorylation of Prkaca 1 0.24 0 0.21
169 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
170 INT110384 Binding of Prkaca and Akap11 1 0.08 0.31 0.2
171 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
172 INT244054 Prkaca Regulation of Neurod1 1 0.02 0.06 0.19
173 INT215167 Phosphorylation of Prkaca Positive_regulation of P2rx2 1 0.06 0.13 0.18
174 INT106334 Olr1254 Positive_regulation of Prkaca 1 0.01 0 0.18
175 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
176 INT250052 Prkaca Regulation of Gria2 1 0.05 0 0.17
177 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
178 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
179 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
180 INT110385 Binding of Prkaca and Trpv1 1 0.14 0.28 0.17
181 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
182 INT329985 Positive_regulation of Prkaca Positive_regulation of Positive_regulation of Mapk14 1 0.15 0.87 0.15
183 INT350069 Prkaca Positive_regulation of Hmox1 1 0.05 0.2 0.15
184 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
185 INT244051 Ppp1ca Regulation of Prkaca 1 0.00 0.18 0.14
186 INT190747 Adcyap1 Regulation of Positive_regulation of Prkaca 1 0.05 0 0.14
187 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
188 INT244017 Prkaca Positive_regulation of Phosphorylation of Gabrg1 1 0.09 0.17 0.13
189 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
190 INT241963 Prkaca Positive_regulation of Positive_regulation of Grm8 1 0.03 0 0.13
191 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
192 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
193 INT326247 Prkcg Positive_regulation of Prkaca 1 0.00 0.62 0.13
194 INT326248 Prkaca Positive_regulation of ras 1 0.00 0.62 0.13
195 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
196 INT276037 Binding of Prkaca and Ppp1cc 1 0.08 0 0.12
197 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
198 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
199 INT276057 Binding of Prkaca and Ppp1r1b 1 0.10 0 0.12
200 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of osteoblast differentiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of osteoblast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT52651 Positive_regulation of Prkaca 136 0.67 40.82 99.16
2 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54
3 INT49111 Negative_regulation of Prkaca 102 0.59 27.44 71.77
4 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52
5 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38
6 INT89055 Phosphorylation of Prkaca 60 0.61 13.41 32.49
7 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96
8 INT96904 Regulation of Prkaca 33 0.44 10.86 24.51
9 INT89805 Gene_expression of Prkaca 45 0.77 11.03 20.77
10 INT77619 Gene_expression of Prkaca 43 0.75 8.55 14.13
11 INT78970 Positive_regulation of Positive_regulation of Prkaca 14 0.47 3.06 11.49
12 INT66382 Positive_regulation of Phosphorylation of Prkaca 33 0.49 7.05 9.69
13 INT40609 Binding of Prkaca 23 0.36 3.42 9.19
14 INT71478 Positive_regulation of Positive_regulation of Prkaca 21 0.37 5.14 8.85
15 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
16 INT142526 Positive_regulation of Gene_expression of Prkaca 12 0.46 2.48 8.05
17 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
18 INT89052 Positive_regulation of Phosphorylation of Prkaca 13 0.37 2.92 7.05
19 INT68466 Negative_regulation of Positive_regulation of Prkaca 6 0.57 2.29 6.83
20 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
21 INT85777 Regulation of Negative_regulation of Prkaca 7 0.46 1.85 5.76
22 INT83597 Phosphorylation of Ptk2 20 0.82 3.24 5.7
23 INT71477 Negative_regulation of Positive_regulation of Prkaca 10 0.37 1.69 5.57
24 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
25 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
26 INT71244 Binding of Prkaca 8 0.30 2.64 4.96
27 INT108354 Negative_regulation of Phosphorylation of Prkaca 18 0.41 6.24 4.37
28 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
29 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
30 INT120742 Negative_regulation of Gene_expression of Prkaca 6 0.24 3.76 3.86
31 INT63121 Binding of APC 29 0.41 23.02 3.8
32 INT117773 Positive_regulation of Phosphorylation of Ptk2 9 0.69 0.89 3.71
33 INT116623 Localization of Prkaca 15 0.73 2.89 3.59
34 INT78969 Regulation of Positive_regulation of Prkaca 5 0.37 1.38 3.29
35 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
36 INT93341 Localization of Prkaca 7 0.59 2.04 2.28
37 INT103179 Regulation of Phosphorylation of Prkaca 6 0.45 0.79 2.15
38 INT169874 Positive_regulation of Gene_expression of Prkaca 11 0.38 1.64 2.01
39 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
40 INT83596 Gene_expression of Ptk2 6 0.76 2.22 1.84
41 INT186427 Negative_regulation of Negative_regulation of Prkaca 2 0.11 0.48 1.73
42 INT3818 Regulation of Apc 13 0.39 12.52 1.68
43 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
44 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
45 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61
46 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
47 INT108352 Regulation of Phosphorylation of Prkaca 8 0.59 0.68 1.53
48 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
49 INT220177 Binding of Apc 21 0.37 15.34 1.37
50 INT131115 Regulation of Phosphorylation of Ptk2 2 0.61 0.3 1.34
51 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
52 INT155346 Negative_regulation of Negative_regulation of Prkaca 4 0.21 1.34 1.23
53 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
54 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
55 INT87346 Binding of PTK2 6 0.37 4.03 1.18
56 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
57 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
58 INT76890 Gene_expression of FGFR2 42 0.65 13.91 1.08
59 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
60 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
61 INT220732 Protein_catabolism of Prkaca 3 0.11 0.61 1.02
62 INT240463 Negative_regulation of Phosphorylation of Prkaca 2 0.23 0.59 0.99
63 INT242134 Localization of Apc 8 0.74 4.83 0.88
64 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
65 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
66 INT131113 Negative_regulation of Ptk2 3 0.58 0.17 0.85
67 INT183182 Negative_regulation of FGFR2 2 0.29 1.25 0.84
68 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78
69 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
70 INT135102 Positive_regulation of Localization of Prkaca 3 0.17 1.21 0.75
71 INT57062 Regulation of APC 24 0.58 14.3 0.7
72 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
73 INT93340 Negative_regulation of Localization of Prkaca 1 0.10 0 0.68
74 INT353152 Localization of PRKACA 1 0.01 1.15 0.66
75 INT150753 Negative_regulation of Gene_expression of Prkaca 1 0.41 0.08 0.65
76 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
77 INT158136 Binding of FGFR2 9 0.26 4.5 0.63
78 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
79 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
80 INT134208 Negative_regulation of Ptk2 19 0.58 23.59 0.52
81 INT61716 Gene_expression of Hemgn 1 0.43 0.19 0.5
82 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
83 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
84 INT117772 Binding of Ptk2 1 0.37 0.17 0.46
85 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
86 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
87 INT164148 Negative_regulation of Localization of Prkaca 4 0.28 0.28 0.41
88 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
89 INT71245 Negative_regulation of Binding of Prkaca 2 0.21 0.06 0.4
90 INT271521 Phosphorylation of Ptk2 10 0.59 11.45 0.39
91 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
92 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
93 INT104989 Positive_regulation of Negative_regulation of Prkaca 2 0.33 0.81 0.37
94 INT93887 Gene_expression of ESRRA 4 0.40 2.63 0.36
95 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
96 INT118243 Transcription of APC 4 0.45 3.33 0.33
97 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
98 INT225667 Transcription of Apc 3 0.52 3.73 0.32
99 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
100 INT195672 Localization of APC 7 0.74 3.76 0.3
101 INT83594 Negative_regulation of Phosphorylation of Ptk2 5 0.42 1.62 0.29
102 INT66380 Regulation of Negative_regulation of Prkaca 2 0.41 0 0.28
103 INT271522 Negative_regulation of Phosphorylation of Ptk2 3 0.19 2.09 0.26
104 INT185926 Regulation of Positive_regulation of Prkaca 5 0.26 0.27 0.25
105 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
106 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
107 INT48785 Gene_expression of PRKACA 1 0.35 0 0.23
108 INT272697 Transcription of Prkaca 2 0.06 0.32 0.22
109 INT329555 Binding of ESRRA 1 0.25 1.55 0.22
110 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
111 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
112 INT308522 Positive_regulation of Positive_regulation of Ptk2 2 0.22 2.37 0.21
113 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
114 INT139482 Regulation of Gene_expression of Prkaca 3 0.56 0.2 0.18
115 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
116 INT283561 Regulation of Gene_expression of Ptk2 5 0.42 1.1 0.17
117 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
118 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
119 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
120 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
121 INT228603 Positive_regulation of Positive_regulation of Apc 1 0.24 0.24 0.17
122 INT327200 Positive_regulation of Gene_expression of ESRRA 3 0.23 0.94 0.16
123 INT275321 Negative_regulation of Transcription of Prkaca 1 0.02 0.32 0.15
124 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
125 INT83595 Negative_regulation of Gene_expression of Ptk2 1 0.23 1.62 0.14
126 INT131114 Positive_regulation of Gene_expression of Ptk2 1 0.49 0.27 0.14
127 INT327399 Negative_regulation of Positive_regulation of Ptk2 7 0.43 4.75 0.13
128 INT269240 Regulation of Ptk2 6 0.42 2.84 0.13
129 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
130 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
131 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
132 INT283567 Regulation of Regulation of Ptk2 1 0.42 0.3 0.13
133 INT99718 Positive_regulation of Gene_expression of FGFR2 9 0.49 4.47 0.12
134 INT242140 Regulation of Localization of Apc 1 0.12 0.12 0.11
135 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1
136 INT283560 Negative_regulation of Gene_expression of Ptk2 6 0.40 4.84 0.09
137 INT268372 Phosphorylation of APC 3 0.81 3.39 0.09
138 INT296963 Positive_regulation of ESRRA 2 0.33 1.17 0.09
139 INT89806 Transcription of Prkaca 2 0.29 0.07 0.09
140 INT271523 Positive_regulation of Gene_expression of Ptk2 6 0.65 8 0.08
141 INT268607 Localization of ESRRA 1 0.04 0.77 0.08
142 INT329554 Regulation of ESRRA 1 0.20 0.8 0.08
143 INT147735 Regulation of Binding of PTK2 1 0.35 0.23 0.08
144 INT268608 Regulation of Localization of ESRRA 1 0.03 0.78 0.08
145 INT144400 Positive_regulation of Gene_expression of PTK2 33 0.70 21.24 0.06
146 INT195679 Positive_regulation of Positive_regulation of APC 6 0.50 4.43 0.05
147 INT235057 Positive_regulation of Negative_regulation of Apc 2 0.30 0.66 0.05
148 INT333217 Regulation of Positive_regulation of Ptk2 1 0.12 0.36 0.05
149 INT329775 Regulation of Regulation of PTK2 1 0.11 0.49 0.05
150 INT89802 Positive_regulation of Transcription of Prkaca 1 0.21 0.07 0.05
151 INT238180 Binding of Ptk2 5 0.35 2.99 0.04
152 INT327396 Positive_regulation of Negative_regulation of Ptk2 1 0.37 0.95 0.04
153 INT295374 Positive_regulation of Ptk2 1 0.34 0.06 0.04
154 INT287842 Negative_regulation of Regulation of Prkaca 1 0.11 0 0.04
155 INT242139 Protein_catabolism of Apc 1 0.17 0.27 0.03
156 INT347119 Localization of FZD1 1 0.68 0.16 0.03
157 INT275364 Positive_regulation of Localization of Prkaca 1 0.28 0.72 0.03
158 INT261754 Phosphorylation of Hemgn 1 0.01 0 0.03
159 INT292474 Negative_regulation of Gene_expression of PTK2 8 0.41 5.17 0
160 INT195681 Positive_regulation of Negative_regulation of APC 5 0.47 3.9 0
161 INT283566 Localization of Ptk2 5 0.75 0.93 0
162 INT207729 Regulation of FGFR2 4 0.22 2.35 0
163 INT262779 Localization of PTK2 3 0.71 2.75 0
164 INT238985 Positive_regulation of FGFR2 3 0.49 1.19 0
165 INT99716 Transcription of FGFR2 2 0.34 0.22 0
166 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0
167 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
168 INT99715 Regulation of Gene_expression of FGFR2 2 0.22 0.19 0
169 INT114739 Positive_regulation of Negative_regulation of Prkaca 2 0.41 2.03 0
170 INT303555 Negative_regulation of Gene_expression of FGFR2 2 0.41 0.31 0
171 INT190759 Transcription of ESRRA 1 0.36 0.23 0
172 INT329558 Regulation of Gene_expression of ESRRA 1 0.23 0 0
173 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
174 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
175 INT327201 Negative_regulation of Gene_expression of ESRRA 1 0.04 0.42 0
176 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
177 INT292478 Negative_regulation of Negative_regulation of PTK2 1 0.41 0.97 0
178 INT337657 Negative_regulation of Negative_regulation of APC 1 0.37 0.99 0
179 INT104591 Negative_regulation of Negative_regulation of Apc 1 0.04 0.16 0
180 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
181 INT337673 Regulation of Positive_regulation of APC 1 0.38 1.44 0
182 INT283564 Positive_regulation of Localization of Ptk2 1 0.47 0 0
183 INT329769 Positive_regulation of Localization of PTK2 1 0.17 1.42 0
184 INT261755 Regulation of Hemgn 1 0.01 0 0
185 INT295392 Positive_regulation of Localization of Ptk2 1 0.37 0 0
186 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
187 INT191087 Regulation of Regulation of Apc 1 0.06 1.02 0
188 INT108353 Positive_regulation of Regulation of Prkaca 1 0.45 0.08 0
189 INT351669 Negative_regulation of Binding of Ptk2 1 0.40 0.73 0
190 INT276018 Regulation of Gene_expression of Prkaca 1 0.25 0 0
191 INT283365 Positive_regulation of Binding of APC 1 0.50 1.43 0
192 INT308354 Gene_expression of Snai2 1 0.58 1.14 0
193 INT337667 Regulation of Transcription of APC 1 0.23 1 0
194 INT97437 Positive_regulation of Hemgn 1 0.04 0 0
195 INT329556 Negative_regulation of Binding of ESRRA 1 0.26 0 0
196 INT308358 Positive_regulation of Gene_expression of Snai2 1 0.45 1.14 0
197 INT286093 Regulation of Binding of Apc 1 0.39 1.08 0
198 INT99717 Positive_regulation of Transcription of FGFR2 1 0.10 0.08 0
199 INT183117 Positive_regulation of Binding of FGFR2 1 0.09 0.81 0
200 INT295387 Localization of Ptk2 1 0.55 0 0
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