GO:0045668

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Name negative regulation of osteoblast differentiation
Categary Process
Go Slim No
Go Link GO:0045668
Unique Molecular Interactions 704
Total Molecular Interactions 907
Total Single Events 7850
Pain Genes Associated 41

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of osteoblast differentiation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of osteoblast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
3 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
4 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
5 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
6 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
7 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
8 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
9 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
10 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
11 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
12 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
13 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
14 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
15 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
16 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
17 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
18 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
19 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
20 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
21 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
22 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
23 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
24 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
25 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
26 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
27 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
28 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
29 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
30 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
31 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
32 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
33 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
34 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
35 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
36 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96
37 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95
38 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
39 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
40 INT141276 Negative_regulation of Il18 Negative_regulation of Gene_expression of Hand2 1 0.25 0.8 0.92
41 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
42 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
43 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
44 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
45 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
46 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
47 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
48 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
49 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
50 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
51 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
52 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
53 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
54 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
55 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
56 INT146780 Positive_regulation of Fgfr1 Positive_regulation of Mapk14 1 0.34 0.95 0.77
57 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
58 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
59 INT243626 Twist1 Regulation of Hand1 1 0.15 1.55 0.72
60 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
61 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
62 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69
63 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
64 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
65 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
66 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67
67 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
68 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
69 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
70 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
71 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
72 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
73 INT243639 Twist1 Negative_regulation of Gene_expression of Il2 1 0.24 1.28 0.65
74 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
75 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
76 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
77 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
78 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
79 INT7402 Positive_regulation of Ucma Positive_regulation of Localization of Gast 1 0.50 0 0.62
80 INT139079 Tnip1 Negative_regulation of Ptch1 1 0.20 0.63 0.62
81 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
82 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
83 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
84 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
85 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
86 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
87 INT102864 Prkaca Regulation of Twist1 1 0.48 0.05 0.58
88 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
89 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
90 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
91 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
92 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
93 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
94 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
95 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
96 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
97 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
98 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54
99 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54
100 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
101 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53
102 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53
103 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
104 INT135755 Pomc Positive_regulation of Positive_regulation of Id3 1 0.17 0 0.5
105 INT135751 Pomc Positive_regulation of Positive_regulation of Id1 1 0.19 0 0.5
106 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
107 INT135752 Pomc Positive_regulation of Id3 1 0.16 0 0.5
108 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
109 INT135753 Pomc Positive_regulation of Gene_expression of Id1 1 0.17 0 0.5
110 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
111 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
112 INT135754 Pomc Positive_regulation of Id1 1 0.17 0 0.5
113 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
114 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
115 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
116 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
117 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48
118 INT67440 Pdyn Regulation of Gene_expression of Tnf 1 0.23 0.19 0.48
119 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
120 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
121 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48
122 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
123 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47
124 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47
125 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46
126 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
127 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
128 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
129 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46
130 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46
131 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
132 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
133 INT148635 Abat Negative_regulation of Gene_expression of Tnf 1 0.10 0.53 0.44
134 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
135 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
136 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44
137 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43
138 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43
139 INT107694 Tnf Positive_regulation of Gene_expression of Cxcl1 1 0.60 0.63 0.43
140 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
141 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43
142 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43
143 INT102862 Prkaca Regulation of Phosphorylation of Twist1 1 0.19 0.1 0.42
144 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
145 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
146 INT52301 Ucma Regulation of Localization of Gast 1 0.28 0 0.41
147 INT52302 Ucma Positive_regulation of Localization of Gast 1 0.47 0 0.41
148 INT52298 Regulation of Ucma Regulation of Gast 1 0.28 0 0.41
149 INT147977 Tnf Positive_regulation of Il4 1 0.01 1.12 0.41
150 INT165568 Tnf Regulation of Gene_expression of Il1b 1 0.41 1.26 0.41
151 INT52300 Ucma Regulation of Sst 1 0.13 0 0.41
152 INT52299 Ucma Regulation of Gast 1 0.28 0 0.41
153 INT139683 Binding of Cldn11 and 2410016O06Rik 1 0.02 1.06 0.4
154 INT139684 Binding of Cd4 and 2410016O06Rik 1 0.02 1.05 0.4
155 INT152158 NENF Regulation of TWIST1 1 0.01 0.33 0.4
156 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
157 INT230500 Il1 Positive_regulation of Gene_expression of Tnf 1 0.07 1.83 0.4
158 INT134761 Ghrl Regulation of Localization of Tnf 1 0.20 0.76 0.4
159 INT154756 Tnf Positive_regulation of Nfkb1 1 0.31 0.78 0.4
160 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4
161 INT165565 Tnf Regulation of Gene_expression of Sdf2l1 1 0.26 1.15 0.39
162 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
163 INT228761 Tnf Positive_regulation of Gene_expression of Ccl17 1 0.20 0.66 0.39
164 INT165566 Tnf Regulation of Gene_expression of Il6 1 0.32 1.15 0.39
165 INT189493 Tnf Positive_regulation of Localization of Darc 1 0.00 0.53 0.37
166 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
167 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36
168 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
169 INT109091 Tnf Positive_regulation of Localization of Il1b 1 0.56 1.08 0.36
170 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
171 INT110994 Tnf Regulation of Il6 1 0.17 0.67 0.36
172 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35
173 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
174 INT163974 Trpv1 Negative_regulation of Gene_expression of Tnf 1 0.34 0.24 0.35
175 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
176 INT243627 Twist1 Regulation of Gene_expression of Ik 1 0.01 0.13 0.34
177 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
178 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
179 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
180 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
181 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
182 INT223962 Tnf Negative_regulation of Gene_expression of Bglap 1 0.21 1.21 0.32
183 INT223964 Tnf Negative_regulation of Bglap 1 0.21 1.2 0.32
184 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32
185 INT243622 Twist1 Regulation of Jak2 1 0.30 0.2 0.32
186 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32
187 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32
188 INT112193 MC1R Regulation of Localization of Tnf 1 0.06 0.15 0.31
189 INT243641 Twist1 Positive_regulation of Socs1 1 0.14 0.13 0.31
190 INT243634 Twist1 Regulation of Socs1 1 0.14 0.13 0.31
191 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31
192 INT9162 Tnf Negative_regulation of Localization of Penk 1 0.34 0.85 0.3
193 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3
194 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3
195 INT243625 Stat4 Positive_regulation of Gene_expression of Twist1 1 0.39 0.75 0.3
196 INT243630 Il12a Positive_regulation of Gene_expression of Twist1 1 0.18 0.69 0.3
197 INT93988 Rab8a Regulation of Hand2 1 0.09 0.78 0.3
198 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
199 INT9161 Tnf Negative_regulation of Localization of Ifng 1 0.20 0.85 0.3
200 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of osteoblast differentiation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of osteoblast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
2 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
3 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
4 INT10166 Localization of Tnf 237 0.81 153.95 88.64
5 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
6 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
7 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
8 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
9 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
10 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
11 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
12 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
13 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
14 INT35406 Localization of Tnf 94 0.81 64.63 31.65
15 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
16 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
17 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
18 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
19 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
20 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
21 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
22 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
23 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
24 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
25 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
26 INT10173 Binding of Tnf 45 0.48 35.6 14.32
27 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
28 INT173505 Localization of Hand2 63 0.57 45.32 13.66
29 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32
30 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
31 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48
32 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28
33 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24
34 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
35 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
36 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47
37 INT68299 Binding of Tnf 17 0.39 12.55 7.49
38 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34
39 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
40 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01
41 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
42 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
43 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
44 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41
45 INT94028 Regulation of Twist1 37 0.44 22.41 5.33
46 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
47 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46
48 INT156131 Binding of Hand2 14 0.25 10.35 3.99
49 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
50 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
51 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
52 INT109391 Gene_expression of Fgfr1 7 0.56 1.78 3.67
53 INT40368 Positive_regulation of LRP5 5 0.49 3.19 3.51
54 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4
55 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
56 INT119218 Positive_regulation of Fgfr1 4 0.58 1.11 3.05
57 INT116540 Binding of Twist1 35 0.48 16.32 2.85
58 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
59 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
60 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
61 INT31994 Negative_regulation of Nbr1 7 0.41 5.54 2.29
62 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
63 INT2844 Positive_regulation of ID1 6 0.70 3.92 2.03
64 INT135744 Positive_regulation of Id1 4 0.49 3.08 2.02
65 INT48880 Positive_regulation of TWIST1 15 0.59 8.6 1.98
66 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
67 INT129239 Positive_regulation of Positive_regulation of Hand2 5 0.43 2.81 1.93
68 INT102861 Phosphorylation of Twist1 6 0.70 0.86 1.81
69 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
70 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
71 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
72 INT7398 Positive_regulation of Ucma 3 0.45 0 1.66
73 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
74 INT180238 Regulation of Gene_expression of Twist1 13 0.61 4.87 1.59
75 INT37005 Regulation of Nbr1 6 0.24 6.33 1.56
76 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
77 INT100672 Transcription of Hand2 9 0.42 2.84 1.47
78 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
79 INT102860 Positive_regulation of Phosphorylation of Twist1 1 0.35 0.15 1.42
80 INT113151 Positive_regulation of Ptch1 7 0.64 3.8 1.41
81 INT10873 Localization of Twist1 21 0.74 10.43 1.37
82 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36
83 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
84 INT26658 Localization of ID1 1 0.32 0.18 1.33
85 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29
86 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
87 INT243621 Transcription of Twist1 13 0.71 4.08 1.23
88 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
89 INT175452 Negative_regulation of Positive_regulation of Hand2 4 0.21 3.78 1.21
90 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
91 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
92 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
93 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
94 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
95 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04
96 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
97 INT141475 Negative_regulation of Gene_expression of TWIST1 5 0.41 3.94 0.97
98 INT235516 Positive_regulation of Localization of Hand2 4 0.36 3.04 0.97
99 INT250699 Binding of CDK6 3 0.33 2.54 0.97
100 INT226419 Negative_regulation of Localization of Hand2 4 0.30 3.17 0.96
101 INT22456 Localization of Nbr1 4 0.70 2.71 0.95
102 INT22455 Binding of Nbr1 8 0.21 10.57 0.93
103 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
104 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
105 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
106 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
107 INT243611 Gene_expression of Twist2 5 0.67 2.85 0.86
108 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86
109 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85
110 INT135299 Binding of PTCH1 10 0.48 12.16 0.84
111 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
112 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81
113 INT9206 Negative_regulation of ID1 5 0.59 2.41 0.79
114 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
115 INT66992 Positive_regulation of Id3 2 0.43 0.23 0.78
116 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
117 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77
118 INT40369 Gene_expression of LRP5 8 0.55 5.63 0.74
119 INT142416 Binding of Ptch1 6 0.34 4.92 0.74
120 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
121 INT166537 Localization of Fgfr1 5 0.40 2.69 0.69
122 INT231558 Regulation of LRP5 2 0.24 1.02 0.68
123 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67
124 INT271488 Negative_regulation of Negative_regulation of Hand2 3 0.18 2.36 0.67
125 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66
126 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
127 INT197832 Localization of MEN1 1 0.80 11.01 0.63
128 INT146775 Phosphorylation of Fgfr1 1 0.53 0.8 0.62
129 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61
130 INT243616 Positive_regulation of Transcription of Twist1 6 0.69 2.09 0.6
131 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
132 INT132588 Positive_regulation of Negative_regulation of Hand2 1 0.03 0.47 0.58
133 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57
134 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
135 INT40367 Positive_regulation of Gene_expression of LRP5 1 0.09 0 0.57
136 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56
137 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
138 INT2845 Gene_expression of ID1 6 0.78 3.97 0.53
139 INT21873 Positive_regulation of Gene_expression of Nbr1 5 0.50 2.09 0.51
140 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
141 INT135747 Gene_expression of Id3 1 0.52 0 0.5
142 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
143 INT135749 Gene_expression of Id1 3 0.58 0.57 0.49
144 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
145 INT146776 Transcription of Fgfr1 1 0.45 0.67 0.49
146 INT146777 Regulation of Transcription of Fgfr1 1 0.23 0.67 0.49
147 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
148 INT140436 Binding of TWIST1 5 0.39 2.34 0.47
149 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
150 INT141194 Regulation of Negative_regulation of Tnf 3 0.42 1.57 0.47
151 INT37068 Regulation of Gene_expression of Nbr1 1 0.41 0.76 0.47
152 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
153 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
154 INT138003 Positive_regulation of Negative_regulation of Tnf 2 0.49 2.07 0.43
155 INT188371 Regulation of Localization of Fgfr1 1 0.10 1.02 0.43
156 INT185255 Positive_regulation of Sox2 3 0.26 1.22 0.42
157 INT35539 Positive_regulation of Positive_regulation of Nbr1 2 0.47 2.52 0.41
158 INT52297 Gene_expression of Ucma 2 0.65 1.3 0.41
159 INT52296 Regulation of Gene_expression of Ucma 1 0.44 0 0.41
160 INT325217 Regulation of Positive_regulation of Hand2 1 0.21 0.32 0.41
161 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
162 INT194745 Regulation of Regulation of Hand2 1 0.03 0.95 0.39
163 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38
164 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
165 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
166 INT226424 Negative_regulation of Transcription of Hand2 1 0.08 0.66 0.37
167 INT129621 Gene_expression of Id3 5 0.75 2.3 0.36
168 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
169 INT159782 Phosphorylation of Tnf 2 0.79 1.51 0.36
170 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
171 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35
172 INT283683 Binding of Id2 5 0.35 0.8 0.35
173 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
174 INT150948 Positive_regulation of Gene_expression of Fgfr1 3 0.15 3.19 0.32
175 INT181918 Positive_regulation of SMAD3 6 0.35 2.62 0.31
176 INT35540 Negative_regulation of Positive_regulation of Nbr1 1 0.25 1.03 0.31
177 INT140795 Positive_regulation of Gene_expression of Smad3 3 0.48 3.16 0.3
178 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29
179 INT116034 Negative_regulation of Transcription of Tnf 2 0.41 0.17 0.29
180 INT130799 Localization of Fgf23 2 0.63 1.94 0.28
181 INT226394 Regulation of Phosphorylation of Hand2 1 0.05 0.97 0.28
182 INT180696 Positive_regulation of Gene_expression of Fgfr1 1 0.32 0.08 0.28
183 INT339992 Positive_regulation of Transcription of HDAC7 1 0.45 1.56 0.28
184 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27
185 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
186 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27
187 INT340001 Transcription of HDAC7 1 0.61 1.5 0.27
188 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26
189 INT254427 Binding of Lrp5 10 0.48 5.43 0.26
190 INT201143 Regulation of Sox2 6 0.44 2.71 0.26
191 INT69595 Localization of Ucma 1 0.73 0 0.26
192 INT69596 Positive_regulation of Localization of Ucma 1 0.49 0 0.26
193 INT268478 Negative_regulation of Positive_regulation of Igfbp5 1 0.26 0.64 0.26
194 INT262797 Regulation of Gene_expression of Smad3 2 0.34 2.27 0.25
195 INT334543 Negative_regulation of Positive_regulation of LRP5 1 0.23 1.81 0.25
196 INT268477 Positive_regulation of Igfbp5 1 0.31 0.63 0.25
197 INT121475 Regulation of Negative_regulation of Twist1 3 0.14 2.43 0.24
198 INT285474 Negative_regulation of Gene_expression of Fgfr1 2 0.40 2.15 0.24
199 INT100671 Positive_regulation of Transcription of Hand2 2 0.36 0.81 0.23
200 INT173655 Binding of LRP5 10 0.39 3.06 0.22
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