GO:0045669

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Name positive regulation of osteoblast differentiation
Categary Process
Go Slim No
Go Link GO:0045669
Unique Molecular Interactions 984
Total Molecular Interactions 1439
Total Single Events 11683
Pain Genes Associated 56

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of osteoblast differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of osteoblast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
2 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
3 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
4 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
5 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
6 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
7 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
8 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
9 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
10 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
11 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
12 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
13 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
14 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
15 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
16 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
17 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
18 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
19 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
20 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
21 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
22 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
23 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
24 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
25 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
26 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
27 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
28 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
29 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
30 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
31 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
32 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
33 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
34 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
35 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
36 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
37 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
38 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
39 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
40 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
41 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
42 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
43 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
44 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
45 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
46 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
47 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
48 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
49 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
50 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
51 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
52 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
53 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
54 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
55 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
56 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
57 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
58 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
59 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
60 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
61 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
62 INT82120 IK Positive_regulation of CEBPB 1 0.00 0 0.92
63 INT13282 Fgf2 Regulation of Ngf 1 0.66 0.21 0.91
64 INT66334 Fgf2 Regulation of Fgf1 1 0.37 0.17 0.9
65 INT13280 Ngf Regulation of Fgf2 1 0.48 0.2 0.9
66 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
67 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
68 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
69 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
70 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
71 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84
72 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
73 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
74 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
75 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
76 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
77 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
78 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
79 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
80 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
81 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
82 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
83 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
84 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
85 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
86 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
87 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
88 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
89 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
90 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
91 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
92 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
93 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
94 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
95 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
96 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
97 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
98 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
99 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
100 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
101 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
102 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
103 INT224726 Negative_regulation of Binding of Fgf2 and Cia1 1 0.01 0.92 0.62
104 INT224727 Binding of Fgf2 and Cia1 1 0.01 0.91 0.61
105 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
106 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
107 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
108 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
109 INT101717 PLAT Positive_regulation of JUND 1 0.17 0.1 0.59
110 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58
111 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
112 INT149480 CEBPD Positive_regulation of CEBPB 1 0.50 0.15 0.58
113 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57
114 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
115 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
116 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
117 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56
118 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
119 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
120 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
121 INT150291 Grk1 Positive_regulation of Gene_expression of Igf1 1 0.16 0.98 0.55
122 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
123 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
124 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
125 INT231711 GPR174 Regulation of Transcription of IL6 1 0.01 0.96 0.54
126 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53
127 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53
128 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52
129 INT171897 Binding of Bmpr2 and Il1 1 0.03 0.84 0.52
130 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
131 INT142882 IGF1 Positive_regulation of Gene_expression of TRPV1 1 0.06 0.57 0.52
132 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
133 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
134 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 0.12 0.09 0.5
135 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5
136 INT97801 Gm5564 Regulation of Gene_expression of IL6 1 0.00 0.07 0.5
137 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49
138 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49
139 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
140 INT100595 RPL21P132 Positive_regulation of IL6 1 0.01 0.43 0.49
141 INT61616 TNF Negative_regulation of Gene_expression of IL6 1 0.37 0.33 0.49
142 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48
143 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
144 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 0.24 1.32 0.48
145 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
146 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48
147 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
148 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
149 INT108568 Calca Positive_regulation of Igf1 1 0.51 0.08 0.48
150 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
151 INT132448 MIR3607 Negative_regulation of IL6 1 0.01 2.45 0.48
152 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
153 INT135589 CSF2 Regulation of IL6 1 0.08 1.27 0.48
154 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47
155 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47
156 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
157 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
158 INT138159 IL6 Positive_regulation of Gene_expression of Mmp3 1 0.00 0.23 0.46
159 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
160 INT233668 Cebpd Negative_regulation of Cebpg 1 0.43 0.66 0.46
161 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45
162 INT67527 MRXS5 Positive_regulation of Gene_expression of IL6 1 0.21 1.5 0.45
163 INT66335 Fgf1 Regulation of Fgf2 1 0.10 0.08 0.45
164 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
165 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
166 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43
167 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43
168 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
169 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
170 INT170157 NPPC Regulation of CSF2 1 0.12 1.36 0.42
171 INT169288 TRPV1 Positive_regulation of Localization of IL6 1 0.24 0 0.42
172 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41
173 INT83913 Il1b Positive_regulation of Gene_expression of IL6 1 0.01 0.5 0.41
174 INT81991 Bmpr2 Positive_regulation of Gene_expression of ODF1 1 0.03 1.59 0.41
175 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
176 INT83916 Il1b Positive_regulation of IL6 1 0.02 0.5 0.41
177 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41
178 INT100594 DCSTAMP Positive_regulation of Gene_expression of IL6 1 0.03 0.24 0.41
179 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
180 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
181 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
182 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4
183 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
184 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4
185 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4
186 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39
187 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39
188 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39
189 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39
190 INT87603 Binding of FOS and Jund 1 0.03 0.77 0.39
191 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
192 INT57219 Binding of ATF3 and JUND 1 0.31 0.39 0.38
193 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
194 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38
195 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
196 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
197 INT328824 Binding of Il6st and TYK2 1 0.02 0 0.38
198 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37
199 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37
200 INT172135 Binding of IL2 and IL6 1 0.01 0.57 0.37

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of osteoblast differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of osteoblast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
3 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
4 INT12082 Localization of IL6 365 0.81 241.78 105.78
5 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
6 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
7 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
8 INT9210 Regulation of IL6 166 0.62 125.61 49.95
9 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
10 INT14559 Gene_expression of Igf1 254 0.78 112 34.17
11 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51
12 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
13 INT86437 Binding of IL6 154 0.48 121.22 29.3
14 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
15 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04
16 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48
17 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
18 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
19 INT61626 Transcription of IL6 73 0.72 42.04 17.86
20 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
21 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12
22 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49
23 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49
24 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02
25 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
26 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
27 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
28 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
29 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
30 INT68133 Localization of Fgf2 36 0.81 15.37 9.14
31 INT34777 Localization of IGF1 82 0.80 42.68 8.62
32 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12
33 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98
34 INT142344 Transcription of Igf1 22 0.69 7.55 6.77
35 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
36 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
37 INT14560 Regulation of Igf1 41 0.59 19.59 6.3
38 INT9494 Positive_regulation of Gene_expression of Igf1 34 0.67 17.77 6.26
39 INT64689 Positive_regulation of Gene_expression of Fgf2 30 0.70 12.05 6.2
40 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1
41 INT9321 Transcription of Igf1 25 0.69 10.2 6.08
42 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
43 INT8916 Regulation of Igf1 45 0.60 13.06 5.81
44 INT151032 Localization of Igf1 49 0.76 26.32 5.71
45 INT9480 Gene_expression of Jund 14 0.77 3.58 5.25
46 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
47 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18
48 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17
49 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
50 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45
51 INT98357 Binding of Gnas 11 0.41 1.87 4.35
52 INT49360 Localization of Igf1 22 0.76 6.96 4.26
53 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24
54 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
55 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77
56 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64
57 INT174816 Binding of IL6R 14 0.09 11.26 3.63
58 INT61028 Negative_regulation of Gene_expression of Jund 3 0.54 0 3.58
59 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
60 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
61 INT168003 Localization of Fgf2 24 0.80 12.52 3.31
62 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
63 INT75133 Positive_regulation of JUND 15 0.51 6.69 3.26
64 INT61547 Regulation of Fgf2 21 0.47 7.23 3.24
65 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23
66 INT89986 Gene_expression of Il6st 5 0.56 2.35 3.15
67 INT101083 Binding of Fgf2 14 0.42 4.12 3.14
68 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
69 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
70 INT39990 Negative_regulation of BMP6 1 0.59 0 3.05
71 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
72 INT115317 Transcription of FGF2 14 0.62 12.79 3
73 INT174864 Positive_regulation of Transcription of FGF2 8 0.44 7.58 3
74 INT88810 Positive_regulation of Gene_expression of FGF2 17 0.50 12.62 2.98
75 INT16130 Binding of IGF1 67 0.48 27.43 2.95
76 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
77 INT65033 Negative_regulation of Fgf2 21 0.59 12.36 2.94
78 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
79 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
80 INT15757 Gene_expression of JUND 11 0.75 2.47 2.86
81 INT259760 Localization of Fbn2 5 0.05 5.55 2.85
82 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67
83 INT69007 Binding of Cebpb 10 0.48 2.21 2.6
84 INT64688 Negative_regulation of Gene_expression of Fgf2 5 0.59 5.07 2.56
85 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55
86 INT259762 Positive_regulation of Fbn2 4 0.05 6.74 2.55
87 INT139735 Positive_regulation of Transcription of Igf1 4 0.53 1.93 2.49
88 INT24672 Localization of FGF2 27 0.71 14.59 2.48
89 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48
90 INT66544 Binding of Igf1 23 0.46 8.33 2.44
91 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
92 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
93 INT97898 Regulation of FGF2 8 0.60 3.85 2.09
94 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08
95 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
96 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
97 INT87436 Regulation of Fgf2 6 0.45 3.95 2.03
98 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02
99 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
100 INT99636 Negative_regulation of Localization of Fgf2 4 0.41 1.32 1.97
101 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95
102 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95
103 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
104 INT64687 Regulation of Gene_expression of Fgf2 7 0.62 2.29 1.89
105 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
106 INT173939 Negative_regulation of IL6R 9 0.11 5.92 1.83
107 INT104912 Gene_expression of Acvr2a 8 0.63 4.48 1.81
108 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
109 INT92677 Positive_regulation of Gene_expression of Fgf2 11 0.69 4.25 1.68
110 INT66709 Transcription of IGF1 13 0.71 5.65 1.64
111 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
112 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
113 INT75559 Negative_regulation of Jund 2 0.54 0.25 1.57
114 INT231917 Gene_expression of Cebpb 10 0.25 4.45 1.56
115 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55
116 INT82122 Positive_regulation of CEBPB 3 0.67 0.51 1.54
117 INT253403 Positive_regulation of Il6st 2 0.28 2.07 1.54
118 INT15758 Positive_regulation of Gene_expression of JUND 5 0.23 0.99 1.53
119 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
120 INT259766 Positive_regulation of Localization of Fbn2 1 0.03 3.09 1.51
121 INT133422 Binding of IL6ST 10 0.40 4.9 1.49
122 INT122547 Positive_regulation of Positive_regulation of FGF2 3 0.44 3.1 1.49
123 INT49361 Regulation of Positive_regulation of Igf1 2 0.45 2.15 1.49
124 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48
125 INT121347 Binding of GNAS 8 0.13 3.99 1.47
126 INT140245 Binding of Gli3 3 0.36 2.65 1.46
127 INT24671 Binding of FGF2 14 0.35 8.73 1.43
128 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42
129 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
130 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
131 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41
132 INT159009 Regulation of Il6st 2 0.18 2 1.41
133 INT162308 Phosphorylation of GNAS 3 0.01 1.71 1.4
134 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
135 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
136 INT90491 Binding of Igf1 25 0.44 9.75 1.36
137 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32
138 INT71304 Binding of CEBPB 3 0.36 2.69 1.32
139 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
140 INT52212 Gene_expression of Bmp6 6 0.64 2.38 1.27
141 INT39991 Negative_regulation of Negative_regulation of BMP6 1 0.43 0 1.24
142 INT60756 Gene_expression of Prkd1 2 0.58 0.14 1.23
143 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
144 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21
145 INT174866 Regulation of Gene_expression of FGF2 4 0.39 7.13 1.2
146 INT98595 Regulation of ILK 6 0.62 3.84 1.16
147 INT142616 Negative_regulation of Positive_regulation of Igf1 5 0.43 1.56 1.16
148 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11
149 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
150 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
151 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
152 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
153 INT147407 Protein_catabolism of FGF2 1 0.91 0.33 1.06
154 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05
155 INT70667 Regulation of JUND 3 0.33 2.36 1.05
156 INT169407 Phosphorylation of IGF1 4 0.63 0.83 1.01
157 INT122141 Binding of Prkd1 4 0.27 0.66 1
158 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
159 INT43484 Binding of Runx2 7 0.37 3.22 0.95
160 INT184236 Positive_regulation of Localization of Fgf2 1 0.27 2.23 0.95
161 INT9479 Positive_regulation of Jund 12 0.69 1.57 0.94
162 INT52213 Regulation of Localization of Bmp6 1 0.44 0.39 0.93
163 INT49658 Positive_regulation of Jund 1 0.02 0.51 0.93
164 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
165 INT114664 Binding of BMP2 12 0.37 6.54 0.91
166 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
167 INT52215 Localization of Bmp6 1 0.73 0.37 0.88
168 INT72715 Positive_regulation of Nppc 4 0.39 1.55 0.87
169 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
170 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
171 INT178498 Negative_regulation of Fgf2 11 0.42 4.21 0.84
172 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
173 INT266562 Gene_expression of Fbn2 1 0.05 0.93 0.84
174 INT266563 Positive_regulation of Gene_expression of Fbn2 1 0.04 0.93 0.84
175 INT202241 Positive_regulation of Negative_regulation of IGF1 5 0.48 1.56 0.82
176 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81
177 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
178 INT142016 Negative_regulation of Gene_expression of CEBPA 1 0.41 0.67 0.8
179 INT142018 Gene_expression of CEBPA 1 0.75 0.66 0.8
180 INT101886 Transcription of Fgf2 8 0.65 4.46 0.78
181 INT80118 Gene_expression of NPPC 2 0.68 4.14 0.77
182 INT141150 Localization of BMP7 4 0.56 2.84 0.76
183 INT259763 Regulation of Fbn2 1 0.02 1.47 0.76
184 INT215783 Localization of Gnas 1 0.12 1.64 0.76
185 INT83350 Negative_regulation of JUND 4 0.52 1.68 0.75
186 INT102311 Regulation of IL6R 4 0.12 2.37 0.74
187 INT101722 Binding of JUND 12 0.31 2.21 0.73
188 INT114604 Positive_regulation of Acvr2a 2 0.41 0 0.73
189 INT68560 Regulation of Gli3 3 0.18 1.51 0.68
190 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
191 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65
192 INT333965 Binding of Il6st 1 0.08 0.9 0.65
193 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
194 INT76142 Positive_regulation of Regulation of Fgf2 2 0.47 0.34 0.64
195 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
196 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63
197 INT197832 Localization of MEN1 1 0.80 11.01 0.63
198 INT39994 Positive_regulation of BMP6 1 0.50 0 0.63
199 INT39992 Positive_regulation of Negative_regulation of BMP6 1 0.47 0 0.62
200 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
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