GO:0045670

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Name regulation of osteoclast differentiation
Categary Process
Go Slim No
Go Link GO:0045670
Unique Molecular Interactions 435
Total Molecular Interactions 563
Total Single Events 5725
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of osteoclast differentiation. They are ordered first by their pain relevance and then by number of times they were reported for regulation of osteoclast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
3 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
4 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
5 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
6 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
7 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
8 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
9 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
10 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
11 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
12 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
13 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
14 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
15 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
16 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
17 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
18 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
19 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
20 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
21 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
22 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
23 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
24 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
25 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
26 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
27 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
28 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
29 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
30 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
31 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
32 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
33 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
34 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
35 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
36 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
37 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
38 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
39 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
40 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
41 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
42 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
43 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
44 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
45 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
46 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
47 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
48 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
49 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
50 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
51 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
52 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
53 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
54 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
55 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
56 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
57 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
58 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
59 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
60 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71
61 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71
62 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
63 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7
64 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
65 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
66 INT187220 Il11 Positive_regulation of Gene_expression of Tnfsf11 1 0.13 0.86 0.69
67 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
68 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
69 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
70 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
71 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
72 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
73 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
74 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
75 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
76 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
77 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
78 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
79 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
80 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
81 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
82 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
83 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
84 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 0.01 0 0.59
85 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
86 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
87 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
88 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
89 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
90 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
91 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
92 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
93 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
94 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
95 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
96 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54
97 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
98 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
99 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54
100 INT38422 Zbtb7a Positive_regulation of Pag1 1 0.30 0.66 0.54
101 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53
102 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53
103 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
104 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
105 INT235390 HTR1A Regulation of BGLAP 1 0.03 0.23 0.51
106 INT187227 Vip Negative_regulation of Gene_expression of Tnfsf11 1 0.35 1.23 0.51
107 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
108 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
109 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
110 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
111 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
112 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
113 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
114 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
115 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
116 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49
117 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48
118 INT67440 Pdyn Regulation of Gene_expression of Tnf 1 0.23 0.19 0.48
119 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
120 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
121 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
122 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
123 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
124 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48
125 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
126 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
127 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
128 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
129 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46
130 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
131 INT235389 Binding of BGLAP and HTR1A 1 0.03 0.15 0.45
132 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
133 INT148635 Abat Negative_regulation of Gene_expression of Tnf 1 0.10 0.53 0.44
134 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44
135 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43
136 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43
137 INT107694 Tnf Positive_regulation of Gene_expression of Cxcl1 1 0.60 0.63 0.43
138 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
139 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43
140 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43
141 INT147977 Tnf Positive_regulation of Il4 1 0.01 1.12 0.41
142 INT165568 Tnf Regulation of Gene_expression of Il1b 1 0.41 1.26 0.41
143 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
144 INT230500 Il1 Positive_regulation of Gene_expression of Tnf 1 0.07 1.83 0.4
145 INT134761 Ghrl Regulation of Localization of Tnf 1 0.20 0.76 0.4
146 INT154756 Tnf Positive_regulation of Nfkb1 1 0.31 0.78 0.4
147 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4
148 INT165565 Tnf Regulation of Gene_expression of Sdf2l1 1 0.26 1.15 0.39
149 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
150 INT228761 Tnf Positive_regulation of Gene_expression of Ccl17 1 0.20 0.66 0.39
151 INT165566 Tnf Regulation of Gene_expression of Il6 1 0.32 1.15 0.39
152 INT45797 ZBTB7A Regulation of Lhb 1 0.36 0.09 0.38
153 INT189493 Tnf Positive_regulation of Localization of Darc 1 0.00 0.53 0.37
154 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
155 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
156 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
157 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37
158 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36
159 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
160 INT109091 Tnf Positive_regulation of Localization of Il1b 1 0.56 1.08 0.36
161 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
162 INT110994 Tnf Regulation of Il6 1 0.17 0.67 0.36
163 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35
164 INT163974 Trpv1 Negative_regulation of Gene_expression of Tnf 1 0.34 0.24 0.35
165 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
166 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
167 INT165764 Tnfsf11 Positive_regulation of Mapk3 1 0.17 1.08 0.33
168 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
169 INT165765 Tnfsf11 Positive_regulation of Nfkb1 1 0.01 1.07 0.33
170 INT165763 Tnfsf11 Positive_regulation of Phosphorylation of Mapk3 1 0.40 1.08 0.33
171 INT223962 Tnf Negative_regulation of Gene_expression of Bglap 1 0.21 1.21 0.32
172 INT311997 Regulation of STAM Regulation of BGLAP 1 0.00 0.61 0.32
173 INT223964 Tnf Negative_regulation of Bglap 1 0.21 1.2 0.32
174 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
175 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
176 INT187223 Il1 Positive_regulation of Gene_expression of Tnfsf11 1 0.09 0.64 0.32
177 INT303106 CAMK4 Positive_regulation of Csf2 1 0.26 0.17 0.31
178 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31
179 INT112193 MC1R Regulation of Localization of Tnf 1 0.06 0.15 0.31
180 INT311991 STAM Regulation of BGLAP 1 0.00 0.61 0.31
181 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
182 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31
183 INT303105 CAMK4 Positive_regulation of Hras1 1 0.04 0.16 0.31
184 INT9162 Tnf Negative_regulation of Localization of Penk 1 0.34 0.85 0.3
185 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
186 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
187 INT9161 Tnf Negative_regulation of Localization of Ifng 1 0.20 0.85 0.3
188 INT164434 Il12a Positive_regulation of Tnf 1 0.00 1.7 0.29
189 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29
190 INT164432 Ifng Positive_regulation of Tnf 1 0.01 1.71 0.29
191 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
192 INT154755 Tnf Positive_regulation of Gene_expression of Ccl2 2 0.23 1.7 0.27
193 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27
194 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
195 INT233515 Pklr Positive_regulation of Gene_expression of Tnf 1 0.05 1.12 0.27
196 INT114389 Csf3 Negative_regulation of Localization of Tnf 1 0.02 0.46 0.26
197 INT135965 Calca Negative_regulation of Gene_expression of Tnf 1 0.33 0.72 0.26
198 INT114388 Csf3 Negative_regulation of Tnf 1 0.02 0.46 0.25
199 INT66257 Negative_regulation of Ptgs1 Positive_regulation of Gene_expression of Tnf 1 0.03 0.44 0.25
200 INT136364 Cpz Positive_regulation of Localization of Tnf 1 0.29 0.36 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of osteoclast differentiation. They are ordered first by their pain relevance and then by number of times they were reported in regulation of osteoclast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
2 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
3 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
4 INT10166 Localization of Tnf 237 0.81 153.95 88.64
5 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
6 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
7 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
8 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
9 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
10 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
11 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
12 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
13 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
14 INT35406 Localization of Tnf 94 0.81 64.63 31.65
15 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
16 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
17 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
18 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
19 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
20 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
21 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
22 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
23 INT10173 Binding of Tnf 45 0.48 35.6 14.32
24 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
25 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81
26 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
27 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
28 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9
29 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
30 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
31 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
32 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26
33 INT68299 Binding of Tnf 17 0.39 12.55 7.49
34 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45
35 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35
36 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
37 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
38 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23
39 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
40 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
41 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
42 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
43 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
44 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07
45 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
46 INT68260 Localization of BGLAP 34 0.78 16.04 4.63
47 INT134646 Gene_expression of Tnfsf11 19 0.69 14.77 4.16
48 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96
49 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
50 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
51 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
52 INT63121 Binding of APC 29 0.41 23.02 3.8
53 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
54 INT91341 Negative_regulation of Gene_expression of BGLAP 17 0.55 4.91 3.02
55 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
56 INT91342 Negative_regulation of Negative_regulation of BGLAP 2 0.55 1.39 2.88
57 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84
58 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
59 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78
60 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
61 INT81989 Positive_regulation of Tnfsf11 11 0.54 7.57 2.4
62 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39
63 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39
64 INT143247 Positive_regulation of CAMK4 9 0.67 5.25 2.28
65 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
66 INT91340 Regulation of Localization of BGLAP 5 0.58 2.82 2.14
67 INT186893 Binding of BGLAP 10 0.37 6.19 2.02
68 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
69 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
70 INT38421 Positive_regulation of Zbtb7a 2 0.50 1.52 1.86
71 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
72 INT3818 Regulation of Apc 13 0.39 12.52 1.68
73 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
74 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
75 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
76 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
77 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
78 INT105551 Transcription of Tnfsf11 6 0.69 4.21 1.38
79 INT220177 Binding of Apc 21 0.37 15.34 1.37
80 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
81 INT153757 Positive_regulation of Mitf 10 0.46 8.38 1.22
82 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
83 INT105552 Positive_regulation of Transcription of Tnfsf11 3 0.31 2.94 1.17
84 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
85 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
86 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
87 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
88 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
89 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
90 INT210586 Negative_regulation of Positive_regulation of Tnfsf11 3 0.41 1.4 1.02
91 INT132847 Negative_regulation of Localization of Tnfsf11 1 0.32 0.16 1.01
92 INT44375 Negative_regulation of ZBTB7A 3 0.57 0.95 0.95
93 INT171963 Positive_regulation of Positive_regulation of Tnfsf11 3 0.42 2.44 0.93
94 INT242134 Localization of Apc 8 0.74 4.83 0.88
95 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
96 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
97 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
98 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
99 INT294998 Positive_regulation of Gene_expression of Tnfsf11 5 0.62 2.98 0.79
100 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
101 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
102 INT312011 Negative_regulation of Binding of BGLAP 1 0.11 1.04 0.76
103 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
104 INT50968 Regulation of Zbtb7a 1 0.38 0.51 0.74
105 INT165760 Positive_regulation of Binding of Tnfsf11 2 0.36 1.83 0.71
106 INT57062 Regulation of APC 24 0.58 14.3 0.7
107 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
108 INT185729 Negative_regulation of Gene_expression of Tnfsf11 3 0.52 2.07 0.69
109 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
110 INT235398 Regulation of Gene_expression of BGLAP 3 0.27 1.03 0.61
111 INT264991 Positive_regulation of Localization of Tnfsf11 5 0.24 3.22 0.59
112 INT213774 Positive_regulation of Positive_regulation of Mitf 1 0.31 1.53 0.58
113 INT108136 Binding of CAMK4 3 0.36 1.62 0.55
114 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
115 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
116 INT207379 Regulation of Negative_regulation of Tnfsf11 2 0.28 1.7 0.5
117 INT44374 Localization of ZBTB7A 1 0.68 0 0.48
118 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
119 INT141194 Regulation of Negative_regulation of Tnf 3 0.42 1.57 0.47
120 INT153758 Binding of Mitf 5 0.47 2.5 0.46
121 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
122 INT224428 Positive_regulation of Localization of BGLAP 5 0.30 2.34 0.44
123 INT340265 Localization of Tnfsf11 2 0.30 1.65 0.44
124 INT341289 Positive_regulation of Localization of Tnfsf11 1 0.13 1.26 0.44
125 INT138003 Positive_regulation of Negative_regulation of Tnf 2 0.49 2.07 0.43
126 INT137846 Regulation of Tnfsf11 5 0.48 1.62 0.42
127 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
128 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
129 INT45769 Positive_regulation of Negative_regulation of ZBTB7A 1 0.49 0 0.41
130 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
131 INT165761 Phosphorylation of Tnfsf11 3 0.75 2.76 0.4
132 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
133 INT97450 Gene_expression of Mitf 36 0.75 17.22 0.39
134 INT187214 Negative_regulation of Binding of Tnfsf11 1 0.25 1.01 0.38
135 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
136 INT57118 Transcription of BGLAP 4 0.56 1.65 0.37
137 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
138 INT93887 Gene_expression of ESRRA 4 0.40 2.63 0.36
139 INT159782 Phosphorylation of Tnf 2 0.79 1.51 0.36
140 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
141 INT118243 Transcription of APC 4 0.45 3.33 0.33
142 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
143 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
144 INT295000 Binding of Tnfsf11 5 0.32 2.27 0.32
145 INT225667 Transcription of Apc 3 0.52 3.73 0.32
146 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
147 INT195672 Localization of APC 7 0.74 3.76 0.3
148 INT116034 Negative_regulation of Transcription of Tnf 2 0.41 0.17 0.29
149 INT225055 Negative_regulation of CAMK4 2 0.04 1.34 0.26
150 INT240202 Regulation of CAMK4 2 0.07 0.12 0.25
151 INT137847 Negative_regulation of Tnfsf11 4 0.42 1.31 0.24
152 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
153 INT131612 Negative_regulation of Mitf 3 0.56 3.91 0.23
154 INT210588 Protein_catabolism of Tnfsf11 1 0.72 1.43 0.23
155 INT230002 Gene_expression of CAMK4 3 0.09 2.59 0.22
156 INT143248 Phosphorylation of CAMK4 2 0.20 0.42 0.22
157 INT329555 Binding of ESRRA 1 0.25 1.55 0.22
158 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
159 INT340249 Positive_regulation of Positive_regulation of BGLAP 1 0.04 0.95 0.21
160 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
161 INT159783 Positive_regulation of Phosphorylation of Tnf 1 0.12 0.39 0.19
162 INT97451 Negative_regulation of Gene_expression of Mitf 3 0.41 0.88 0.17
163 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
164 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
165 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
166 INT240208 Regulation of Regulation of CAMK4 1 0.07 0.12 0.17
167 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
168 INT228603 Positive_regulation of Positive_regulation of Apc 1 0.24 0.24 0.17
169 INT327200 Positive_regulation of Gene_expression of ESRRA 3 0.23 0.94 0.16
170 INT213794 Phosphorylation of Mitf 2 0.42 2.56 0.15
171 INT339756 Negative_regulation of Gene_expression of CAMK4 1 0.02 0.74 0.14
172 INT213773 Phosphorylation of Tfe3 1 0.39 1.22 0.14
173 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
174 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
175 INT294997 Regulation of Gene_expression of Tnfsf11 1 0.35 0.81 0.13
176 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
177 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13
178 INT213771 Positive_regulation of Gene_expression of Mitf 4 0.48 2.01 0.12
179 INT242140 Regulation of Localization of Apc 1 0.12 0.12 0.11
180 INT213766 Regulation of Mitf 6 0.44 3.18 0.1
181 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1
182 INT97449 Transcription of Mitf 4 0.69 4.28 0.09
183 INT268372 Phosphorylation of APC 3 0.81 3.39 0.09
184 INT296963 Positive_regulation of ESRRA 2 0.33 1.17 0.09
185 INT295324 Regulation of Binding of Tnf 2 0.44 1.11 0.09
186 INT57117 Negative_regulation of Transcription of BGLAP 1 0.35 0.83 0.09
187 INT248596 Regulation of Binding of BGLAP 1 0.27 0.39 0.09
188 INT268607 Localization of ESRRA 1 0.04 0.77 0.08
189 INT230000 Positive_regulation of Transcription of CAMK4 1 0.04 0.88 0.08
190 INT329554 Regulation of ESRRA 1 0.20 0.8 0.08
191 INT229997 Transcription of CAMK4 1 0.06 0.87 0.08
192 INT266996 Regulation of Phosphorylation of CAMK4 1 0.04 0 0.08
193 INT268608 Regulation of Localization of ESRRA 1 0.03 0.78 0.08
194 INT144491 Negative_regulation of Transcription of Tnfsf11 1 0.42 0.82 0.07
195 INT195679 Positive_regulation of Positive_regulation of APC 6 0.50 4.43 0.05
196 INT235057 Positive_regulation of Negative_regulation of Apc 2 0.30 0.66 0.05
197 INT314713 Positive_regulation of Gene_expression of ZBTB7A 1 0.49 1.92 0.05
198 INT104032 Negative_regulation of Localization of BGLAP 4 0.33 2.22 0.04
199 INT232197 Positive_regulation of Phosphorylation of Tnfsf11 1 0.46 0.6 0.04
200 INT232196 Negative_regulation of Negative_regulation of Tnfsf11 1 0.39 1.5 0.04
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