GO:0045720

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Name negative regulation of integrin biosynthetic process
Categary Process
Go Slim No
Go Link GO:0045720
Unique Molecular Interactions 107
Total Molecular Interactions 147
Total Single Events 1149
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of integrin biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of integrin biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
2 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
3 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
4 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
5 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
6 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
7 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
8 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
9 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
10 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24
11 INT252427 IGKV2D-29 Regulation of Gene_expression of AR 1 0.02 0 0.24
12 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23
13 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23
14 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23
15 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23
16 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23
17 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17
18 INT122361 Binding of AR and OPRM1 1 0.26 0.14 0.16
19 INT122362 AR Positive_regulation of Positive_regulation of OPRM1 1 0.32 0.19 0.14
20 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13
21 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
22 INT169128 Trove2 Negative_regulation of Gene_expression of AR 1 0.05 0.94 0.13
23 INT223040 AR Positive_regulation of Negative_regulation of TFPI 1 0.03 0 0.13
24 INT354620 AR Positive_regulation of Hspg2 1 0.00 0 0.12
25 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
26 INT185918 AR Positive_regulation of Gene_expression of NOS2 1 0.12 0.21 0.11
27 INT220743 Binding of AR and EGFR 1 0.01 0.46 0.1
28 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08
29 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08
30 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07
31 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07
32 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07
33 INT293813 ERBB2 Positive_regulation of Positive_regulation of AR 1 0.09 0.45 0.07
34 INT201866 Binding of AR and PGR 1 0.07 0.34 0.06
35 INT338019 Egf Positive_regulation of AR 1 0.07 1.02 0.05
36 INT349665 Positive_regulation of Binding of AR and TFPI 1 0.02 0 0.05
37 INT349667 Binding of AR and TFPI 1 0.02 0 0.05
38 INT209644 Binding of AR and C4B 1 0.00 0.32 0.04
39 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04
40 INT213383 Srd5a3 Negative_regulation of Gene_expression of AR 1 0.01 0.7 0.04
41 INT319384 Binding of AR and SCGB2A2 1 0.01 1.36 0.04
42 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04
43 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04
44 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03
45 INT326736 AR Regulation of Gene_expression of ARG2 1 0.34 0.43 0.03
46 INT185651 GOPC Positive_regulation of AR 1 0.03 0.06 0.03
47 INT349661 PYCARD Positive_regulation of AR 1 0.08 0 0.03
48 INT198143 Binding of AR and ANTXR2 1 0.01 0.19 0.03
49 INT326742 AR Regulation of Gene_expression of ARG1 1 0.24 0.43 0.03
50 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03
51 INT218964 Dlst Regulation of AR 1 0.01 0 0.03
52 INT265730 Binding of AR and VEGFA 1 0.09 0 0
53 INT338180 Binding of AR and STAT3 1 0.18 0.3 0
54 INT304020 AR Regulation of TP53 1 0.24 1.11 0
55 INT339404 Binding of Ar and Tymp 1 0.10 0.06 0
56 INT218963 Dlst Negative_regulation of AR 1 0.00 0.1 0
57 INT209636 TRPV1 Regulation of Gene_expression of AR 1 0.17 0.38 0
58 INT339403 Negative_regulation of Binding of Ar and Tymp 1 0.12 0 0
59 INT293809 MAPK1 Positive_regulation of AR 1 0.03 0.12 0
60 INT209633 AR Regulation of Gene_expression of PCa 1 0.06 1.19 0
61 INT213365 AR Regulation of Gene_expression of VEGFA 1 0.09 1.52 0
62 INT338018 Binding of AR and Flna 1 0.11 0.33 0
63 INT209634 Binding of AR and PCa 1 0.04 1.03 0
64 INT293818 AKT1 Positive_regulation of Gene_expression of AR 1 0.05 0.31 0
65 INT349666 Binding of AR and PYCARD 1 0.06 0 0
66 INT326740 Gene_expression of AR Negative_regulation of Gene_expression of ARG2 1 0.24 0.8 0
67 INT209630 ALG12 Regulation of Gene_expression of AR 1 0.13 0.38 0
68 INT209635 AR Positive_regulation of ALG12 1 0.14 0.32 0
69 INT338194 Regulation of VAV3 Regulation of AR 1 0.31 0.49 0
70 INT293803 Negative_regulation of ERBB2 Negative_regulation of Gene_expression of AR 1 0.10 0 0
71 INT293819 EPHB2 Positive_regulation of AR 1 0.23 0.12 0
72 INT338197 CCND1 Negative_regulation of AR 1 0.24 0 0
73 INT354619 AR Positive_regulation of Gene_expression of Nppa 1 0.00 0.38 0
74 INT338022 Cuedc2 Positive_regulation of Protein_catabolism of AR 1 0.23 0.29 0
75 INT218960 Binding of AR and Esyt1 1 0.00 0 0
76 INT209637 AR Positive_regulation of TRPV1 1 0.18 0.32 0
77 INT293806 AR Positive_regulation of PIK3CG 1 0.06 0.12 0
78 INT209629 AR Negative_regulation of Gene_expression of MRFAP1 1 0.26 0.16 0
79 INT185652 Binding of AR and GOPC 1 0.03 0 0
80 INT338182 CDCP1 Positive_regulation of Phosphorylation of AR 1 0.01 0.29 0
81 INT339407 Negative_regulation of Binding of AR and Tymp 1 0.04 0 0
82 INT102124 Binding of AR and ESRRB 1 0.03 0.13 0
83 INT218965 Esyt1 Negative_regulation of AR 1 0.00 0 0
84 INT209641 AR Positive_regulation of PCa 1 0.06 1.17 0
85 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
86 INT265737 Binding of AR and NRP1 1 0.10 0 0
87 INT326743 Gene_expression of AR Negative_regulation of Gene_expression of ARG1 1 0.32 0.8 0
88 INT209638 AR Regulation of MRFAP1 1 0.12 0.41 0
89 INT339406 Binding of AR and Tymp 1 0.03 0.06 0
90 INT338023 Psma7 Positive_regulation of AR 1 0.17 0.38 0
91 INT279635 Ar Regulation of Abpe 1 0.01 1.55 0
92 INT265756 Positive_regulation of Binding of AR and NRP1 1 0.10 0 0
93 INT293816 Binding of AR and PIK3CG 1 0.03 0.27 0
94 INT198110 Ar Positive_regulation of Gene_expression of Aqp9 1 0.13 0 0
95 INT218962 Dlst Regulation of Gene_expression of AR 1 0.01 0 0
96 INT185654 DBT Negative_regulation of AR 1 0.02 0.09 0
97 INT338020 Binding of AR and Ddr1 1 0.03 0.45 0
98 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0
99 INT293810 Binding of AR and RORC 1 0.01 0.13 0
100 INT338185 VAV3 Regulation of Positive_regulation of AR 1 0.19 0.49 0
101 INT338193 VAV3 Regulation of AR 1 0.31 0.49 0
102 INT209643 AR Positive_regulation of PYCR1 1 0.31 1.17 0
103 INT213364 AR Regulation of VEGFA 1 0.09 0.68 0
104 INT117173 OCM Regulation of Transcription of AR 1 0.18 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of integrin biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of integrin biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
2 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
3 INT35366 Binding of AR 87 0.47 30.52 8.9
4 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
5 INT99091 Regulation of AR 70 0.45 31.68 5.05
6 INT5205 Localization of AR 43 0.80 12.87 4.63
7 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
8 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
9 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
10 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
11 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
12 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
13 INT82932 Transcription of AR 14 0.67 5.75 1.34
14 INT68500 Regulation of Ar 6 0.27 4.16 1.32
15 INT213379 Phosphorylation of AR 6 0.63 2.03 1.21
16 INT209679 Positive_regulation of Regulation of AR 3 0.37 1.88 0.96
17 INT156529 Positive_regulation of Gene_expression of Ar 1 0.05 0.09 0.8
18 INT185669 Positive_regulation of Localization of AR 7 0.33 1.83 0.73
19 INT156060 Regulation of Binding of AR 2 0.09 0.42 0.69
20 INT17493 Binding of Ar 14 0.48 3.62 0.6
21 INT49343 Positive_regulation of Ar 8 0.42 4.38 0.58
22 INT104312 Positive_regulation of Transcription of AR 2 0.37 0.96 0.38
23 INT17492 Negative_regulation of Binding of Ar 3 0.59 0.76 0.28
24 INT293387 Regulation of Localization of AR 1 0.05 0 0.28
25 INT266974 Protein_catabolism of AR 2 0.34 1.91 0.27
26 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25
27 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25
28 INT185930 Regulation of Positive_regulation of AR 3 0.20 1.01 0.25
29 INT152667 Negative_regulation of Transcription of AR 3 0.42 0.72 0.24
30 INT112378 Negative_regulation of Regulation of Ar 1 0.43 0.19 0.23
31 INT257784 Positive_regulation of Phosphorylation of AR 2 0.45 0.96 0.21
32 INT49346 Transcription of Ar 3 0.63 0.8 0.14
33 INT123527 Negative_regulation of Gene_expression of Ar 2 0.10 0 0.14
34 INT152669 Negative_regulation of Localization of AR 2 0.25 0.75 0.13
35 INT185673 Negative_regulation of Negative_regulation of AR 3 0.28 1.12 0.12
36 INT243079 Regulation of Ar 3 0.08 1.22 0.12
37 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11
38 INT162428 Localization of Ar 4 0.37 2.4 0.07
39 INT162430 Negative_regulation of Positive_regulation of Ar 1 0.21 1.52 0.07
40 INT243082 Binding of Ar 2 0.11 1.81 0.06
41 INT185666 Positive_regulation of Binding of AR 2 0.33 0.19 0.04
42 INT213380 Regulation of Negative_regulation of AR 1 0.35 0.72 0.04
43 INT213363 Regulation of Gene_expression of Ar 2 0.11 1.63 0.03
44 INT123526 Positive_regulation of Gene_expression of Ar 2 0.11 1.29 0
45 INT209673 Negative_regulation of Binding of AR 2 0.27 0.5 0
46 INT182748 Positive_regulation of Transcription of Ar 1 0.46 0.43 0
47 INT287660 Negative_regulation of Negative_regulation of Ar 1 0.03 0.07 0
48 INT185672 Positive_regulation of Negative_regulation of AR 1 0.27 0 0
49 INT335677 Regulation of Localization of Ar 1 0.00 0 0
50 INT146803 Negative_regulation of Gene_expression of Ar 1 0.16 0.08 0
51 INT293401 Regulation of Gene_expression of Ar 1 0.06 0.07 0
52 INT152665 Negative_regulation of Regulation of AR 1 0.25 0.38 0
53 INT152664 Regulation of Transcription of AR 1 0.16 0.25 0
54 INT293772 Negative_regulation of Positive_regulation of AR 1 0.19 0 0
55 INT123516 Phosphorylation of Ar 1 0.19 0.07 0
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