GO:0045721

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Name negative regulation of gluconeogenesis
Categary Process
Go Slim No
Go Link GO:0045721
Unique Molecular Interactions 1096
Total Molecular Interactions 1592
Total Single Events 16764
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of gluconeogenesis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of gluconeogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
2 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
3 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
4 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
5 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
6 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
7 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
8 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
9 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
10 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
11 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
12 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
13 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
14 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
15 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
16 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
17 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
18 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
19 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
20 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
21 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
22 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
23 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
24 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
25 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
26 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
27 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
28 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
29 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
30 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
31 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
32 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
33 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
34 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
35 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
36 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
37 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
38 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
39 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
40 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
41 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
42 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
43 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
44 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
45 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
46 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
47 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
48 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
49 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
50 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
51 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
52 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
53 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
54 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
55 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
56 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
57 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
58 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
59 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
60 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
61 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
62 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
63 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
64 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
65 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
66 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
67 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
68 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
69 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
70 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
71 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
72 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
73 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
74 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
75 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
76 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
77 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
78 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
79 INT40424 CCK Regulation of Localization of INS 1 0.02 0 0.97
80 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
81 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
82 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96
83 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
84 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
85 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
86 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
87 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
88 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
89 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
90 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
91 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
92 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
93 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
94 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
95 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
96 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
97 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
98 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
99 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
100 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
101 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
102 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
103 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
104 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
105 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
106 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
107 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
108 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
109 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
110 INT131463 NTRK1 Regulation of Localization of INS 1 0.41 0.63 0.8
111 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
112 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
113 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
114 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79
115 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78
116 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
117 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
118 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
119 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77
120 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
121 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
122 INT41165 Gtf3a Regulation of INS 1 0.00 0.15 0.74
123 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
124 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
125 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
126 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
127 INT41164 Binding of INS and SST 1 0.07 0.14 0.73
128 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
129 INT31643 POMC Regulation of INS 1 0.59 0.62 0.73
130 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
131 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
132 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
133 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
134 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
135 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
136 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
137 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
138 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
139 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
140 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
141 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
142 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
143 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
144 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
145 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
146 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
147 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
148 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
149 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
150 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
151 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
152 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
153 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
154 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
155 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
156 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
157 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
158 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
159 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
160 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
161 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64
162 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
163 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63
164 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
165 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
166 INT155458 Tnfrsf1a Regulation of Gene_expression of Il6 1 0.22 1.11 0.63
167 INT71526 Regulation of Il1b Positive_regulation of Il6 1 0.17 0.14 0.62
168 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62
169 INT71527 Negative_regulation of OPRD1 Negative_regulation of Positive_regulation of Il6 1 0.00 0.15 0.62
170 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
171 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61
172 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
173 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6
174 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
175 INT71525 Oprd1 Regulation of Il6 1 0.16 0.19 0.6
176 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
177 INT91699 Il6 Regulation of Gene_expression of Oprl1 1 0.06 0 0.6
178 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
179 INT83424 Binding of CD40LG and ADIPOQ 2 0.13 1 0.59
180 INT83426 ADIPOQ Negative_regulation of Binding of CD40LG 2 0.21 1 0.59
181 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
182 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58
183 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
184 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
185 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58
186 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
187 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
188 INT103165 NGF Positive_regulation of Localization of INS 1 0.05 0 0.58
189 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57
190 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57
191 INT142312 Lalba Negative_regulation of Localization of Il6 1 0.23 0.73 0.57
192 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
193 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
194 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
195 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
196 INT192971 Positive_regulation of Il6 Positive_regulation of Localization of Stat3 1 0.03 0.86 0.56
197 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
198 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54
199 INT29252 Regulation of INS Positive_regulation of GH1 1 0.26 0.08 0.54
200 INT231711 GPR174 Regulation of Transcription of IL6 1 0.01 0.96 0.54

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of gluconeogenesis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of gluconeogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT812 Localization of INS 1026 0.81 515.6 145.31
7 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
8 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
9 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
10 INT12082 Localization of IL6 365 0.81 241.78 105.78
11 INT19511 Localization of Il6 212 0.81 118.17 67.67
12 INT11937 Localization of Il6 228 0.81 139.83 64.39
13 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
14 INT10706 Regulation of Il6 150 0.62 93.23 62.34
15 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
16 INT251 Regulation of INS 398 0.62 232.47 55.04
17 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
18 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
19 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
20 INT9210 Regulation of IL6 166 0.62 125.61 49.95
21 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
22 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
23 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
24 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
25 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
26 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
27 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
28 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
29 INT9655 Regulation of Il6 98 0.62 70.92 31.95
30 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
31 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
32 INT86437 Binding of IL6 154 0.48 121.22 29.3
33 INT51474 Binding of Il6 55 0.48 44.99 20.52
34 INT49985 Transcription of Il6 62 0.72 40.13 20.29
35 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
36 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
37 INT61626 Transcription of IL6 73 0.72 42.04 17.86
38 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
39 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58
40 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
41 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
42 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
43 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46
44 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
45 INT14572 Binding of INS 205 0.48 175.43 13.38
46 INT54763 Binding of Il6 82 0.48 63.27 12.89
47 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
48 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
49 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
50 INT117502 Positive_regulation of Adipoq 70 0.63 40.43 12.03
51 INT50933 Transcription of Il6 38 0.72 24.31 11.58
52 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
53 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
54 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
55 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
56 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
57 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
58 INT125136 Regulation of Adipoq 24 0.56 16.82 7.23
59 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2
60 INT146043 Positive_regulation of Gene_expression of Adipoq 39 0.67 29.93 6.12
61 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
62 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
63 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
64 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
65 INT117499 Negative_regulation of Adipoq 28 0.56 24.15 5.07
66 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
67 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9
68 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83
69 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67
70 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58
71 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
72 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
73 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
74 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
75 INT117501 Positive_regulation of Gene_expression of Adipoq 24 0.63 12.99 3.1
76 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
77 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
78 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91
79 INT32623 Negative_regulation of Regulation of INS 16 0.43 10.96 2.9
80 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
81 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64
82 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
83 INT26974 Negative_regulation of Adipoq 27 0.52 26.01 2.59
84 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47
85 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
86 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27
87 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26
88 INT95621 Gene_expression of Gck 6 0.64 1.06 2.26
89 INT135451 Positive_regulation of Positive_regulation of Adipoq 3 0.40 2.06 2.24
90 INT129871 Positive_regulation of Gene_expression of Gck 1 0.28 0.15 2.19
91 INT26177 Regulation of Regulation of INS 19 0.44 11.32 2.18
92 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
93 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
94 INT138029 Binding of Adipoq 10 0.40 6.81 2.04
95 INT134633 Localization of Adipoq 9 0.60 6.39 2.03
96 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86
97 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
98 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
99 INT227273 Localization of Adipoq 22 0.72 18.04 1.72
100 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
101 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55
102 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47
103 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
104 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
105 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
106 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
107 INT109104 Positive_regulation of Protein_catabolism of INS 4 0.50 4.44 1.24
108 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
109 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15
110 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15
111 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14
112 INT105346 Gene_expression of Gck 5 0.71 3.05 1.14
113 INT183046 Transcription of INS 25 0.70 11.14 1.13
114 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
115 INT58470 Negative_regulation of Binding of INS 14 0.43 7.2 1.01
116 INT134260 Negative_regulation of Transcription of Il6 2 0.25 1.39 0.99
117 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
118 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
119 INT160140 Regulation of Binding of Adipoq 1 0.37 0.87 0.92
120 INT227270 Regulation of Gene_expression of Adipoq 5 0.55 7.35 0.85
121 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
122 INT192851 Phosphorylation of Il6 7 0.68 3.12 0.82
123 INT151927 Regulation of Gene_expression of Adipoq 3 0.43 3.32 0.81
124 INT142013 Positive_regulation of Regulation of Adipoq 1 0.03 0.65 0.78
125 INT28020 Binding of Adipoq 10 0.36 11.49 0.77
126 INT12057 Regulation of Negative_regulation of INS 7 0.40 3.92 0.76
127 INT300843 Regulation of Transcription of Il6 3 0.37 3.4 0.76
128 INT52196 Negative_regulation of Regulation of Il6 3 0.42 3.42 0.74
129 INT158354 Negative_regulation of Binding of Il6 2 0.20 2.21 0.71
130 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67
131 INT183789 Positive_regulation of Phosphorylation of INS 5 0.50 4.87 0.64
132 INT14570 Regulation of Positive_regulation of INS 8 0.45 4.97 0.62
133 INT261602 Positive_regulation of Binding of Il6 2 0.50 1.75 0.62
134 INT138730 Negative_regulation of Negative_regulation of Il6 3 0.09 1.04 0.61
135 INT118310 Negative_regulation of Positive_regulation of Adipoq 2 0.34 2.47 0.61
136 INT179488 Positive_regulation of Transcription of Adipoq 3 0.37 0.5 0.6
137 INT264490 Regulation of Negative_regulation of Il6 2 0.23 1.18 0.6
138 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56
139 INT61025 Negative_regulation of Negative_regulation of Il6 3 0.43 1.15 0.56
140 INT14571 Regulation of Binding of INS 2 0.23 2.44 0.53
141 INT227272 Transcription of Adipoq 8 0.64 8.29 0.49
142 INT220268 Regulation of Regulation of Il6 2 0.12 0.89 0.49
143 INT83430 Positive_regulation of Binding of ADIPOQ 2 0.21 0.85 0.49
144 INT115189 Regulation of Phosphorylation of IL6 1 0.04 0 0.48
145 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46
146 INT213286 Positive_regulation of Binding of INS 6 0.50 4.85 0.45
147 INT83434 Negative_regulation of Binding of ADIPOQ 1 0.39 1.14 0.45
148 INT98447 Positive_regulation of Negative_regulation of Il6 1 0.44 0.75 0.45
149 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44
150 INT285471 Negative_regulation of Binding of Il6 2 0.21 1.33 0.41
151 INT308980 Positive_regulation of Negative_regulation of Adipoq 3 0.33 2.3 0.4
152 INT14569 Positive_regulation of Negative_regulation of INS 4 0.36 3.52 0.37
153 INT105342 Positive_regulation of Gene_expression of Gck 2 0.46 0.83 0.36
154 INT82552 Negative_regulation of Regulation of Il6 2 0.38 1.43 0.36
155 INT105343 Negative_regulation of Gene_expression of Gck 1 0.39 0 0.36
156 INT183066 Positive_regulation of Transcription of INS 8 0.49 5.31 0.34
157 INT105345 Localization of Gck 1 0.60 0 0.33
158 INT179491 Transcription of Adipoq 4 0.51 0.98 0.32
159 INT143536 Protein_catabolism of Il6 2 0.69 1.89 0.31
160 INT227268 Negative_regulation of Transcription of Adipoq 4 0.52 4.93 0.3
161 INT105341 Regulation of Gck 1 0.25 0 0.3
162 INT194162 Protein_catabolism of Il6 2 0.12 0.79 0.27
163 INT211287 Regulation of Binding of Il6 1 0.06 0.1 0.27
164 INT207293 Negative_regulation of Negative_regulation of INS 12 0.49 6 0.26
165 INT201071 Positive_regulation of Regulation of Il6 2 0.39 0.45 0.25
166 INT298665 Positive_regulation of Protein_catabolism of IL6 1 0.09 2.03 0.25
167 INT253941 Positive_regulation of Localization of Adipoq 5 0.24 2.59 0.21
168 INT150529 Positive_regulation of Negative_regulation of Adipoq 2 0.37 1.76 0.18
169 INT197872 Regulation of Regulation of Adipoq 3 0.35 1.11 0.17
170 INT28026 Positive_regulation of Binding of Adipoq 1 0.27 0 0.17
171 INT137455 Protein_catabolism of ADIPOQ 1 0.66 0.25 0.17
172 INT228162 Negative_regulation of Localization of Adipoq 1 0.38 1.29 0.17
173 INT308978 Negative_regulation of Regulation of Adipoq 1 0.28 0.92 0.17
174 INT263001 Regulation of Gene_expression of ADIPOQ 5 0.45 3.77 0.16
175 INT95619 Negative_regulation of Gck 3 0.39 0.88 0.16
176 INT163262 Transcription of ADIPOQ 5 0.52 2.81 0.14
177 INT188222 Positive_regulation of Regulation of IL6 2 0.29 0.51 0.13
178 INT298669 Negative_regulation of Protein_catabolism of IL6 1 0.08 1.02 0.13
179 INT262999 Negative_regulation of Gene_expression of ADIPOQ 7 0.43 9.52 0.12
180 INT150107 Negative_regulation of Gck 2 0.31 0.89 0.12
181 INT297431 Phosphorylation of Gck 2 0.54 0.29 0.11
182 INT157267 Negative_regulation of Localization of Adipoq 1 0.24 0.94 0.09
183 INT327816 Regulation of Positive_regulation of ADIPOQ 1 0.04 1.2 0.09
184 INT228295 Negative_regulation of Transcription of INS 2 0.43 1.1 0.07
185 INT238167 Localization of Sik1 1 0.06 0.16 0.07
186 INT238165 Gene_expression of Sik1 1 0.05 0.2 0.07
187 INT229324 Gene_expression of GCK 3 0.35 0.48 0.06
188 INT253097 Negative_regulation of Phosphorylation of Il6 1 0.35 0.23 0.06
189 INT229320 Positive_regulation of Gene_expression of GCK 1 0.05 0.48 0.06
190 INT95623 Negative_regulation of Gene_expression of Gck 3 0.39 0.91 0.05
191 INT353069 Positive_regulation of Positive_regulation of ADIPOQ 1 0.13 1.75 0.05
192 INT245905 Negative_regulation of Transcription of ADIPOQ 1 0.42 1.26 0.05
193 INT240929 Positive_regulation of Gck 1 0.42 0 0.04
194 INT228584 Phosphorylation of Adipoq 1 0.38 0.61 0.04
195 INT251940 Positive_regulation of Transcription of ADIPOQ 1 0.01 0 0.04
196 INT238158 Phosphorylation of Sik1 1 0.06 0.69 0.03
197 INT238181 Binding of Sik1 1 0.04 0.18 0.03
198 INT240621 Negative_regulation of Localization of ADIPOQ 1 0.39 0.64 0.03
199 INT95940 Regulation of GCK 1 0.15 0 0.03
200 INT238182 Positive_regulation of Localization of Sik1 1 0.04 0 0.03
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