GO:0045722

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Name positive regulation of gluconeogenesis
Categary Process
Go Slim No
Go Link GO:0045722
Unique Molecular Interactions 65
Total Molecular Interactions 93
Total Single Events 377
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of gluconeogenesis. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of gluconeogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
2 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21
3 INT112912 Nts Positive_regulation of Phosphorylation of Arpp19 1 0.18 0 0.21
4 INT306261 AKT2 Negative_regulation of Phosphorylation of FOXO1 1 0.25 0.41 0.17
5 INT254497 GOPC Regulation of Transcription of HNF4A 1 0.02 0.72 0.16
6 INT240899 Negative_regulation of Ros1 Positive_regulation of Phosphorylation of Foxo1 1 0.14 0.41 0.15
7 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
8 INT189559 STK11 Positive_regulation of SNRK 1 0.03 0.36 0.11
9 INT317392 Negative_regulation of Binding of Stk11 and Amp1 1 0.05 0.34 0.1
10 INT254496 Binding of HNF4A and GOPC 1 0.10 0.34 0.08
11 INT240897 Akt1 Negative_regulation of Positive_regulation of Foxo1 1 0.21 0.22 0.08
12 INT317398 Amp1 Positive_regulation of Phosphorylation of Stk11 1 0.05 0.22 0.07
13 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07
14 INT317391 Amp1 Positive_regulation of Stk11 1 0.05 0.22 0.07
15 INT253139 Il6 Positive_regulation of Phosphorylation of Stk11 1 0.26 0.34 0.07
16 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06
17 INT262190 Foxo1 Positive_regulation of Pck1 1 0.04 0.15 0.06
18 INT317389 Binding of Prkag1 and Stk11 1 0.16 0.2 0.06
19 INT317397 Negative_regulation of Binding of Prkag1 and Stk11 1 0.19 0.2 0.06
20 INT352385 MIR27A Regulation of Foxo1 1 0.45 0.48 0.04
21 INT240881 Gene_expression of Sod1 Positive_regulation of Phosphorylation of Foxo1 1 0.38 0.07 0.03
22 INT262198 Foxo1 Positive_regulation of Igfbp1 1 0.11 0.08 0.03
23 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03
24 INT317388 Stk11 Regulation of Positive_regulation of Prkag1 1 0.23 0.11 0.03
25 INT317404 Acc Positive_regulation of Stk11 1 0.41 0.06 0.03
26 INT240883 Foxo1 Positive_regulation of Ppargc1a 1 0.43 0.06 0.03
27 INT351972 Binding of Agt and Stk11 1 0.27 0.74 0
28 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0
29 INT219416 CCNA2 Regulation of HNF4A 1 0.00 0.11 0
30 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 0.00 0.25 0
31 INT204325 Binding of PPARGC1A and SIRT1 1 0.39 0.19 0
32 INT182952 KCNIP3 Positive_regulation of HNF4A 1 0.02 0.45 0
33 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0
34 INT351975 Agt Positive_regulation of Stk11 1 0.34 0.39 0
35 INT182922 FRA8E Positive_regulation of HNF4A 1 0.00 0.2 0
36 INT204322 Binding of ADIPOQ and Positive_regulation of Gene_expression of PPARGC1A 1 0.30 0.07 0
37 INT307214 Hnf4a Regulation of Ppara 1 0.18 0.35 0
38 INT182926 VDR Positive_regulation of HNF4A 1 0.02 0.09 0
39 INT326836 Binding of HNF4A and PLD2 1 0.03 0.35 0
40 INT219410 CCNF Regulation of HNF4A 1 0.01 0.11 0
41 INT351984 Gene_expression of Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.8 0
42 INT182938 Binding of HNF4A and KCNIP3 1 0.01 0.2 0
43 INT219426 CDK2 Regulation of HNF4A 1 0.01 0.11 0
44 INT219420 CCNE2 Regulation of HNF4A 1 0.00 0.11 0
45 INT173123 Binding of HNF4A and PPARA 1 0.10 0.19 0
46 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
47 INT204326 SIRT1 Positive_regulation of PPARGC1A 1 0.51 0.19 0
48 INT183018 Dre Positive_regulation of HNF4A 1 0.00 0.09 0
49 INT251069 Binding of Cldn5 and Positive_regulation of Foxo1 1 0.09 0.15 0
50 INT351985 Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.79 0
51 INT182957 CDKN1A Negative_regulation of HNF4A 1 0.02 0.11 0
52 INT182927 Binding of HNF4A and HRES1 1 0.00 0 0
53 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0
54 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0
55 INT289523 Binding of Foxo1 and Positive_regulation of Sirt1 1 0.36 0.13 0
56 INT262191 Binding of Nr1i2 and Foxo1 1 0.22 0.09 0
57 INT151589 Stk11 Positive_regulation of Prkag1 1 0.41 0.17 0
58 INT326902 Binding of HNF4A and Tcf4 1 0.02 0.35 0
59 INT262174 Binding of Casr and Foxo1 1 0.05 0.09 0
60 INT289521 Binding of Foxo1 and Positive_regulation of Acsm3 1 0.01 0.12 0
61 INT259094 STK11 Positive_regulation of Gene_expression of TCEAL1 1 0.18 5.5 0
62 INT204319 SIRT1 Regulation of Gene_expression of PPARGC1A 1 0.50 0.12 0
63 INT289535 Negative_regulation of Sirt1 Negative_regulation of Binding of Foxo1 1 0.29 0.14 0
64 INT240944 Akt1 Positive_regulation of Phosphorylation of Foxo1 1 0.22 0.06 0
65 INT281607 Foxo1 Positive_regulation of Transcription of Trim63 1 0.27 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of gluconeogenesis. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of gluconeogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
2 INT172630 Binding of HNF4A 16 0.05 7.78 1.22
3 INT84130 Gene_expression of Foxo1 1 0.26 0.97 1.22
4 INT172616 Regulation of HNF4A 9 0.06 4.25 1.02
5 INT226179 Phosphorylation of Foxo1 15 0.68 3.14 0.7
6 INT253108 Phosphorylation of Stk11 4 0.65 2.13 0.52
7 INT275642 Negative_regulation of HNF4A 4 0.05 2.08 0.44
8 INT122525 Regulation of FOXO1 3 0.58 1.76 0.44
9 INT265898 Transcription of FOXO1 2 0.50 2.29 0.41
10 INT351970 Gene_expression of Stk11 1 0.75 33.89 0.35
11 INT106253 Positive_regulation of HNF4A 14 0.29 3.88 0.34
12 INT183208 Transcription of HNF4A 7 0.11 3.15 0.28
13 INT139652 Negative_regulation of Arpp19 1 0.12 0.1 0.26
14 INT265902 Phosphorylation of FOXO1 2 0.59 1.47 0.24
15 INT276188 Negative_regulation of Foxo1 5 0.40 1.75 0.23
16 INT275639 Positive_regulation of Binding of HNF4A 2 0.04 0.87 0.21
17 INT112901 Phosphorylation of Arpp19 1 0.34 0 0.21
18 INT265903 Gene_expression of FOXO1 3 0.48 2.66 0.2
19 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19
20 INT60751 Positive_regulation of Gene_expression of HNF4A 2 0.49 3.5 0.19
21 INT226163 Negative_regulation of Phosphorylation of Foxo1 2 0.36 0.83 0.19
22 INT351969 Positive_regulation of Gene_expression of Stk11 1 0.67 21.03 0.19
23 INT289565 Binding of Foxo1 5 0.45 2.47 0.17
24 INT306278 Negative_regulation of Phosphorylation of FOXO1 1 0.31 0.41 0.17
25 INT164022 Regulation of Gene_expression of HNF4A 1 0.03 0.82 0.16
26 INT276173 Phosphorylation of Foxo1 7 0.56 1.79 0.15
27 INT196603 Gene_expression of STK11 5 0.55 6.75 0.15
28 INT265904 Localization of FOXO1 3 0.25 2.28 0.15
29 INT276178 Negative_regulation of Phosphorylation of Foxo1 3 0.30 1.03 0.15
30 INT240848 Positive_regulation of Phosphorylation of Foxo1 4 0.58 0.28 0.14
31 INT189633 Regulation of STK11 3 0.41 3.57 0.14
32 INT240838 Negative_regulation of Foxo1 5 0.43 2.04 0.13
33 INT226162 Binding of Foxo1 3 0.28 0.77 0.13
34 INT106227 Binding of STK11 3 0.42 3.13 0.13
35 INT156350 Positive_regulation of FOXO1 2 0.49 1.53 0.13
36 INT189583 Transcription of STK11 2 0.49 4.43 0.13
37 INT330233 Positive_regulation of Stk11 2 0.67 8.15 0.13
38 INT287917 Phosphorylation of HNF4A 1 0.08 0.07 0.13
39 INT151587 Positive_regulation of Stk11 2 0.38 0.44 0.12
40 INT240827 Positive_regulation of Foxo1 3 0.58 1.01 0.11
41 INT226187 Transcription of Foxo1 1 0.06 0.6 0.11
42 INT240861 Regulation of Phosphorylation of Foxo1 1 0.51 0.23 0.1
43 INT126667 Localization of HNF4A 2 0.06 0.45 0.08
44 INT240847 Negative_regulation of Positive_regulation of Foxo1 1 0.36 0.22 0.08
45 INT204332 Positive_regulation of PPARGC1A 7 0.67 1.42 0.07
46 INT253107 Regulation of Stk11 2 0.33 0.3 0.07
47 INT253102 Negative_regulation of Stk11 1 0.31 0.22 0.07
48 INT265900 Positive_regulation of Gene_expression of FOXO1 1 0.19 1.1 0.06
49 INT330228 Phosphorylation of Stk11 1 0.18 0.27 0.05
50 INT330227 Positive_regulation of Positive_regulation of Stk11 1 0.11 0.06 0.05
51 INT287925 Regulation of Binding of HNF4A 1 0.06 1.1 0.05
52 INT289592 Positive_regulation of Foxo1 2 0.41 1.44 0.04
53 INT351967 Negative_regulation of Gene_expression of Stk11 1 0.57 0.89 0.04
54 INT351966 Binding of Stk11 1 0.36 2.15 0.04
55 INT301583 Positive_regulation of Negative_regulation of Foxo1 1 0.21 0.84 0.04
56 INT301520 Negative_regulation of Negative_regulation of Foxo1 1 0.27 0.84 0.04
57 INT289571 Positive_regulation of Binding of Foxo1 2 0.48 1.94 0.03
58 INT253104 Gene_expression of Stk11 2 0.53 0.07 0.03
59 INT289566 Transcription of Foxo1 1 0.47 0.36 0.03
60 INT317354 Regulation of Phosphorylation of Stk11 1 0.36 0.12 0.03
61 INT289573 Gene_expression of Foxo1 7 0.73 1.92 0
62 INT204372 Transcription of PPARGC1A 3 0.67 0.28 0
63 INT281596 Regulation of Foxo1 2 0.19 0.18 0
64 INT240915 Regulation of Foxo1 2 0.39 1.31 0
65 INT259109 Negative_regulation of STK11 2 0.54 2.11 0
66 INT204346 Positive_regulation of Transcription of PPARGC1A 2 0.49 0.28 0
67 INT323478 Localization of Foxo1 1 0.43 0.08 0
68 INT240836 Positive_regulation of Positive_regulation of Foxo1 1 0.36 0.55 0
69 INT289582 Negative_regulation of Binding of Foxo1 1 0.29 0.13 0
70 INT213579 Binding of FOXO1 1 0.46 1.48 0
71 INT326868 Positive_regulation of Transcription of HNF4A 1 0.04 0.08 0
72 INT262081 Negative_regulation of Binding of Foxo1 1 0.18 0.08 0
73 INT204350 Negative_regulation of Transcription of PPARGC1A 1 0.41 0.1 0
74 INT351968 Negative_regulation of Stk11 1 0.42 4.84 0
75 INT289544 Positive_regulation of Phosphorylation of Foxo1 1 0.34 0.24 0
76 INT204333 Regulation of PPARGC1A 1 0.26 0.34 0
77 INT351971 Regulation of Stk11 1 0.26 0.43 0
78 INT204357 Positive_regulation of Positive_regulation of PPARGC1A 1 0.49 0.07 0
79 INT281591 Localization of Foxo1 1 0.48 0 0
80 INT204347 Positive_regulation of Negative_regulation of PPARGC1A 1 0.49 0 0
81 INT204369 Negative_regulation of Positive_regulation of PPARGC1A 1 0.41 0.07 0
82 INT317352 Positive_regulation of Phosphorylation of Stk11 1 0.32 0 0
83 INT289577 Regulation of Gene_expression of Foxo1 1 0.31 0.24 0
84 INT242091 Phosphorylation of STK11 1 0.30 1.93 0
85 INT289557 Negative_regulation of Negative_regulation of Foxo1 1 0.30 0.18 0
86 INT301374 Localization of Stk11 1 0.23 1.58 0
87 INT204366 Positive_regulation of Gene_expression of PPARGC1A 1 0.67 1.44 0
88 INT204337 Regulation of Gene_expression of PPARGC1A 1 0.44 0.48 0
89 INT204339 Binding of PPARGC1A 1 0.35 0.19 0
90 INT323467 Positive_regulation of Localization of Foxo1 1 0.29 0.08 0
91 INT204329 Positive_regulation of Regulation of PPARGC1A 1 0.45 0.07 0
92 INT326878 Negative_regulation of Gene_expression of HNF4A 1 0.03 0.43 0
93 INT204341 Negative_regulation of Gene_expression of PPARGC1A 1 0.41 0 0
94 INT204351 Negative_regulation of PPARGC1A 1 0.42 0.25 0
95 INT287915 Positive_regulation of Positive_regulation of HNF4A 1 0.06 0.37 0
96 INT289559 Positive_regulation of Gene_expression of Foxo1 1 0.34 0.5 0
97 INT289560 Negative_regulation of Gene_expression of Foxo1 1 0.29 0.48 0
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