GO:0045742

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Name positive regulation of epidermal growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0045742
Unique Molecular Interactions 631
Total Molecular Interactions 868
Total Single Events 6780
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of epidermal growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of epidermal growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT87891 Agt Regulation of Cck 1 0.28 0 1.97
3 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78
4 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
5 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
6 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
7 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
8 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
9 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
10 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11
11 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
12 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
13 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
14 INT12050 Agt Positive_regulation of Localization of Oxt 1 0.29 0 0.91
15 INT34457 AGT Positive_regulation of POMC 1 0.01 0 0.91
16 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91
17 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
18 INT69424 Binding of Agt and Oprd1 1 0.14 0 0.84
19 INT34458 AGT Negative_regulation of PENK 1 0.00 0 0.81
20 INT108811 Esr2 Positive_regulation of Binding of Oprm1 1 0.46 0.44 0.79
21 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
22 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
23 INT39095 Negative_regulation of Agt Positive_regulation of Localization of Ren 1 0.38 0 0.73
24 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
25 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
26 INT141063 Agt Regulation of Agtr1a 1 0.28 1.18 0.68
27 INT291548 Binding of Gper and Sec22b 1 0.02 0.94 0.67
28 INT47145 Penk Negative_regulation of Agt 1 0.06 0 0.66
29 INT162878 Agt Regulation of Ang 1 0.21 1.15 0.66
30 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
31 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64
32 INT57421 Oprd1 Regulation of Agt 1 0.29 0 0.62
33 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
34 INT109802 Binding of Esr2 and Oprl1 1 0.22 0.1 0.59
35 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
36 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
37 INT56117 Agt Positive_regulation of Positive_regulation of CGA 1 0.00 0 0.56
38 INT73367 Agt Negative_regulation of Localization of Calca 1 0.43 0.26 0.54
39 INT34459 AGT Negative_regulation of MBTPS1 1 0.01 0 0.54
40 INT88024 Ifng Positive_regulation of Gene_expression of Faslg 2 0.50 1.19 0.53
41 INT132438 Binding of AGT and OXTR 1 0.08 1.03 0.53
42 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
43 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
44 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
45 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
46 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
47 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
48 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49
49 INT39078 Binding of Agt and Penk 1 0.24 0.42 0.48
50 INT47144 Negative_regulation of Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
51 INT47146 Creg2-ps1 Positive_regulation of Agt 1 0.01 0 0.48
52 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
53 INT39077 Agt Negative_regulation of Prss12 1 0.05 0.44 0.46
54 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
55 INT151958 Negative_regulation of Agt Positive_regulation of Agtrap 1 0.39 0 0.44
56 INT151959 Agt Positive_regulation of Agtrap 1 0.63 0 0.44
57 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43
58 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
59 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
60 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
61 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
62 INT254347 FASLG Negative_regulation of Gene_expression of CHI3L1 1 0.13 0.92 0.42
63 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
64 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
65 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
66 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41
67 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
68 INT346151 Binding of ADM and GPER 1 0.01 0.99 0.41
69 INT264522 Binding of GPER and PTGDS 1 0.03 1.22 0.4
70 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
71 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
72 INT64384 Agt Negative_regulation of Son 1 0.26 0 0.39
73 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
74 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
75 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
76 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
77 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37
78 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
79 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
80 INT39092 Agt Negative_regulation of Ren 1 0.39 0 0.37
81 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
82 INT176373 IL18 Regulation of FASLG 1 0.41 0.4 0.35
83 INT44112 Agt Regulation of Penk 1 0.08 0 0.35
84 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
85 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
86 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
87 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34
88 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
89 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
90 INT162157 Binding of SGCG and Agt 1 0.33 0.35 0.33
91 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
92 INT291543 Binding of Dlat and Gper 1 0.15 0.37 0.33
93 INT147436 Agt Positive_regulation of Gene_expression of Ros1 1 0.02 0.5 0.33
94 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33
95 INT229363 Negative_regulation of Binding of Agt and Agtr1a 2 0.22 0.9 0.32
96 INT44127 Agt Negative_regulation of DSPP 1 0.02 0 0.32
97 INT350214 Binding of GPER and HSPG2 1 0.00 0.12 0.32
98 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
99 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
100 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31
101 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
102 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
103 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
104 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
105 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
106 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28
107 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28
108 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
109 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
110 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
111 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
112 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
113 INT45545 Agt Positive_regulation of Oxt 1 0.23 0 0.27
114 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
115 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26
116 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26
117 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
118 INT9528 Agt Positive_regulation of Localization of Pomc 2 0.50 0.14 0.25
119 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25
120 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25
121 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25
122 INT297258 Binding of Agt and Agtr2 1 0.23 0.7 0.25
123 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
124 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
125 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
126 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25
127 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
128 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
129 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
130 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
131 INT41589 Binding of AGT and Prl 1 0.00 0 0.24
132 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24
133 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
134 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24
135 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
136 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
137 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23
138 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
139 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23
140 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
141 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23
142 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
143 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
144 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21
145 INT229360 Agt Positive_regulation of Agtr1a 2 0.48 1.26 0.2
146 INT300469 Ros1 Regulation of Gene_expression of Fasl 1 0.03 0.88 0.2
147 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2
148 INT88022 Tnf Positive_regulation of Gene_expression of Faslg 1 0.26 0.76 0.2
149 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
150 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2
151 INT249993 Binding of Agt and Igkv4-55 1 0.02 0.49 0.2
152 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19
153 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
154 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
155 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
156 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
157 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
158 INT184540 Agt Regulation of Gene_expression of Ccl2 1 0.08 1.66 0.18
159 INT41978 Binding of Agt and Htr1a 1 0.41 0.54 0.18
160 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
161 INT36568 AGT Positive_regulation of FBF1 1 0.39 0.5 0.17
162 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
163 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
164 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
165 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
166 INT175328 FASLG Positive_regulation of FAS 1 0.01 0.9 0.17
167 INT36567 Negative_regulation of AGT Positive_regulation of FBF1 1 0.36 0.5 0.17
168 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
169 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
170 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
171 INT234720 Cxcl1 Positive_regulation of Gene_expression of Faslg 1 0.08 0.2 0.16
172 INT234719 Cxcl1 Regulation of Gene_expression of Faslg 1 0.08 0.2 0.15
173 INT21509 Agt Regulation of Edn1 1 0.53 0 0.15
174 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
175 INT266036 Gpr30 Positive_regulation of Positive_regulation of Mapk1 1 0.19 0.24 0.15
176 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
177 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
178 INT72817 Agt Negative_regulation of Avp 1 0.07 0.34 0.14
179 INT347071 Negative_regulation of REN Negative_regulation of Positive_regulation of AGT 1 0.35 0.44 0.14
180 INT34430 AGT Positive_regulation of Localization of POMC 1 0.30 0.31 0.14
181 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
182 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14
183 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14
184 INT293115 Agt Regulation of Positive_regulation of Crh 1 0.16 0.37 0.14
185 INT293117 Agt Regulation of Gene_expression of Aqp2 1 0.23 0.36 0.14
186 INT293123 Agtr1a Regulation of Negative_regulation of Agt 1 0.14 0.25 0.14
187 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
188 INT33749 Crh Positive_regulation of Localization of Agt 1 0.31 0 0.13
189 INT59808 Binding of AGT and PLCB1 1 0.02 0 0.13
190 INT173404 GPER Regulation of Itgam 1 0.02 0.41 0.13
191 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
192 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
193 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
194 INT59809 AGT Positive_regulation of PLCB1 1 0.03 0 0.13
195 INT59810 ADRA1D Positive_regulation of AGT 1 0.01 0 0.13
196 INT173373 GPER Regulation of FCGR3B 1 0.03 0.39 0.12
197 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
198 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
199 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12
200 INT107226 Agt Positive_regulation of AFF1 1 0.01 0 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of epidermal growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of epidermal growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
3 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
4 INT385 Gene_expression of Agt 182 0.78 63.62 37.91
5 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
6 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08
7 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67
8 INT1158 Regulation of Agt 106 0.61 29.4 30.29
9 INT37296 Binding of Esr1 117 0.43 62.51 27.33
10 INT20462 Binding of ESR1 210 0.44 102.7 26.34
11 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11
12 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73
13 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
14 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91
15 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
16 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
17 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92
18 INT2066 Localization of Agt 56 0.80 9.95 16.25
19 INT92354 Localization of ESR1 77 0.75 33.04 15.51
20 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
21 INT2038 Localization of Esr1 104 0.79 40.12 13.27
22 INT3962 Regulation of AGT 50 0.62 20.96 13.01
23 INT4199 Binding of Agt 76 0.48 21.06 12.66
24 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
25 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04
26 INT398 Localization of AGT 45 0.78 16.97 11.54
27 INT8065 Binding of AGT 54 0.48 20.54 10.85
28 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21
29 INT386 Positive_regulation of Gene_expression of Agt 37 0.70 15.92 8.73
30 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
31 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51
32 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92
33 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83
34 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
35 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
36 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14
37 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84
38 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
39 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
40 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05
41 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
42 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
43 INT3332 Protein_catabolism of AGT 23 0.87 3.17 4.39
44 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
45 INT77385 Gene_expression of Esr2 18 0.75 4.69 3.92
46 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
47 INT25200 Positive_regulation of GPER 13 0.05 1.75 3.67
48 INT20461 Binding of Esr1 34 0.48 9.58 3.66
49 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
50 INT133768 Regulation of Fasl 10 0.44 10.24 3.32
51 INT188406 Binding of Fasl 19 0.44 24.67 3.17
52 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
53 INT10553 Regulation of GPER 13 0.15 2.12 3.02
54 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
55 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
56 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54
57 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45
58 INT148071 Gene_expression of Agt 42 0.74 44.9 2.43
59 INT4270 Negative_regulation of Negative_regulation of Agt 10 0.43 1.08 2.43
60 INT95136 Binding of FASLG 6 0.33 8.01 2.41
61 INT137960 Positive_regulation of FASLG 8 0.67 6.5 2.34
62 INT54615 Gene_expression of GPER 25 0.75 8.23 2.27
63 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27
64 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27
65 INT93395 Transcription of Faslg 6 0.51 5.64 2.26
66 INT10201 Positive_regulation of Localization of Agt 8 0.50 0.97 2.21
67 INT12005 Negative_regulation of Localization of Agt 6 0.57 1.49 2.06
68 INT79915 Positive_regulation of Agt 27 0.56 12.97 1.96
69 INT12801 Negative_regulation of Regulation of Agt 4 0.43 1.2 1.96
70 INT109800 Binding of Esr2 8 0.42 1.79 1.93
71 INT88016 Negative_regulation of Gene_expression of Faslg 5 0.54 2.18 1.93
72 INT43944 Negative_regulation of Positive_regulation of Agt 4 0.42 1.44 1.93
73 INT102147 Negative_regulation of Faslg 5 0.19 4.56 1.92
74 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
75 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
76 INT130775 Regulation of FASLG 4 0.30 5.8 1.82
77 INT33845 Binding of GPER 20 0.36 5.61 1.81
78 INT15980 Positive_regulation of Positive_regulation of Agt 6 0.50 2.99 1.76
79 INT153918 Binding of Esr2 3 0.33 2.56 1.7
80 INT3152 Transcription of Agt 7 0.72 5.09 1.68
81 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
82 INT107299 Transcription of Fasl 6 0.68 5 1.64
83 INT30076 Negative_regulation of Esr2 1 0.01 0 1.63
84 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
85 INT93394 Positive_regulation of Transcription of Faslg 1 0.24 3.57 1.57
86 INT161379 Localization of Fasl 8 0.67 11.05 1.56
87 INT137819 Binding of Faslg 3 0.09 1.78 1.51
88 INT88015 Positive_regulation of Faslg 5 0.65 5.73 1.44
89 INT34768 Negative_regulation of Negative_regulation of AGT 10 0.25 2.79 1.42
90 INT8067 Negative_regulation of Binding of AGT 12 0.25 10.33 1.39
91 INT239215 Binding of Agt 9 0.38 6.75 1.35
92 INT11306 Regulation of Gene_expression of Agt 7 0.45 3.29 1.31
93 INT11241 Transcription of AGT 4 0.52 1.83 1.27
94 INT158078 Gene_expression of Gper 7 0.67 1.13 1.26
95 INT8511 Localization of Esr1 6 0.80 3.27 1.26
96 INT135551 Positive_regulation of Gene_expression of FASLG 2 0.67 6.71 1.26
97 INT19319 Negative_regulation of Binding of Agt 9 0.42 3.42 1.24
98 INT135803 Regulation of Gene_expression of Fasl 6 0.36 4.35 1.24
99 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
100 INT79916 Negative_regulation of Agt 14 0.47 6 1.22
101 INT130774 Transcription of FASLG 5 0.67 2.02 1.22
102 INT47644 Positive_regulation of Localization of AGT 4 0.45 1.24 1.2
103 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
104 INT28594 Positive_regulation of Transcription of Agt 2 0.47 1.3 1.15
105 INT115621 Positive_regulation of Binding of AGT 1 0.02 0 1.15
106 INT159162 Binding of Gper 2 0.48 1.69 1.12
107 INT124317 Regulation of Gene_expression of FASLG 2 0.23 1.54 1.1
108 INT188407 Positive_regulation of Binding of Fasl 1 0.48 3.67 1.08
109 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
110 INT158077 Regulation of Gper 2 0.35 0.91 1.04
111 INT66862 Regulation of Esr2 3 0.24 1.56 1.01
112 INT157531 Gene_expression of Gpr30 2 0.53 1.12 0.99
113 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
114 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
115 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
116 INT99941 Negative_regulation of Positive_regulation of Fasl 3 0.44 2.24 0.93
117 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
118 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
119 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
120 INT130770 Positive_regulation of Transcription of FASLG 1 0.22 0.68 0.87
121 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
122 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83
123 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
124 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
125 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
126 INT86852 Regulation of Faslg 3 0.42 1.67 0.79
127 INT63694 Regulation of Positive_regulation of GPER 1 0.00 0.41 0.79
128 INT158075 Positive_regulation of Esr2 1 0.28 0.5 0.77
129 INT10554 Regulation of Regulation of GPER 3 0.01 0.45 0.76
130 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75
131 INT34715 Regulation of Regulation of AGT 2 0.37 0.96 0.75
132 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
133 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
134 INT66598 Negative_regulation of GPER 8 0.04 3.83 0.72
135 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
136 INT148074 Regulation of Agt 9 0.49 5.42 0.7
137 INT38735 Protein_catabolism of Agt 7 0.99 2.79 0.7
138 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
139 INT160461 Phosphorylation of Agt 1 0.31 0.4 0.7
140 INT160463 Positive_regulation of Phosphorylation of Agt 1 0.19 0.41 0.7
141 INT34769 Regulation of Gene_expression of AGT 3 0.19 1.39 0.67
142 INT150831 Localization of Gper 1 0.65 0.33 0.67
143 INT70121 Protein_catabolism of GPER 1 0.00 0.06 0.65
144 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
145 INT95135 Negative_regulation of Gene_expression of FASLG 4 0.20 2.99 0.64
146 INT354814 Positive_regulation of Localization of Fasl 3 0.29 3.61 0.64
147 INT9836 Negative_regulation of Negative_regulation of Esr1 3 0.29 0.95 0.63
148 INT173748 Phosphorylation of Esr1 11 0.77 5.7 0.55
149 INT328633 Transcription of GPER 2 0.06 2.57 0.54
150 INT175219 Binding of NUP62 31 0.27 4.51 0.53
151 INT40021 Regulation of Binding of Agt 4 0.59 1.53 0.53
152 INT173744 Positive_regulation of Positive_regulation of Esr1 10 0.43 7.05 0.52
153 INT32618 Regulation of Positive_regulation of Agt 2 0.43 0.42 0.52
154 INT190899 Negative_regulation of Phosphorylation of ESR1 3 0.33 1.01 0.49
155 INT30075 Localization of Esr2 2 0.01 0.78 0.49
156 INT47645 Negative_regulation of Localization of AGT 2 0.11 1.09 0.49
157 INT188405 Positive_regulation of Positive_regulation of Fasl 4 0.64 3.54 0.48
158 INT240710 Positive_regulation of Regulation of Esr1 1 0.09 1.34 0.47
159 INT99588 Positive_regulation of Binding of Agt 2 0.69 0.23 0.45
160 INT14039 Regulation of Regulation of Agt 1 0.30 0 0.44
161 INT323752 Negative_regulation of FASLG 2 0.18 2.36 0.43
162 INT33017 Negative_regulation of Protein_catabolism of AGT 3 0.37 0 0.42
163 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41
164 INT109801 Transcription of Esr2 2 0.69 2.08 0.41
165 INT348631 Regulation of Esr2 1 0.40 0.87 0.4
166 INT88021 Regulation of Gene_expression of Faslg 4 0.60 2.6 0.38
167 INT268930 Regulation of Regulation of Esr1 2 0.41 0.48 0.38
168 INT186535 Negative_regulation of Gene_expression of Esr2 2 0.25 1.07 0.38
169 INT95132 Negative_regulation of Binding of FASLG 1 0.18 0.63 0.38
170 INT178630 Positive_regulation of Negative_regulation of ESR1 2 0.04 0.64 0.35
171 INT236580 Regulation of Binding of Esr1 4 0.39 1.1 0.34
172 INT95605 Regulation of Binding of AGT 3 0.44 0.2 0.34
173 INT27928 Phosphorylation of AGT 1 0.52 0.15 0.34
174 INT27929 Negative_regulation of Phosphorylation of AGT 1 0.27 0.15 0.34
175 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33
176 INT183916 Negative_regulation of Binding of Esr1 1 0.06 0.91 0.32
177 INT192845 Negative_regulation of Positive_regulation of Esr1 2 0.35 1.15 0.31
178 INT66863 Regulation of Gene_expression of Esr2 1 0.03 0 0.31
179 INT73915 Negative_regulation of Negative_regulation of Esr1 1 0.40 0.06 0.31
180 INT4636 Positive_regulation of Regulation of Agt 4 0.50 1.3 0.3
181 INT43398 Regulation of Localization of Agt 1 0.28 0 0.3
182 INT323166 Binding of Gpr30 1 0.16 0.2 0.28
183 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27
184 INT135805 Positive_regulation of Negative_regulation of Fasl 1 0.48 0.24 0.27
185 INT3331 Positive_regulation of Protein_catabolism of AGT 1 0.33 0 0.27
186 INT167917 Regulation of Gene_expression of GPER 2 0.26 0.58 0.26
187 INT164617 Protein_catabolism of Agt 2 0.79 5.3 0.25
188 INT88018 Positive_regulation of Positive_regulation of Faslg 1 0.47 0.75 0.23
189 INT239213 Localization of Agt 6 0.64 3.26 0.22
190 INT96972 Positive_regulation of Binding of Esr1 4 0.22 1.35 0.21
191 INT94547 Localization of Faslg 1 0.76 0.71 0.21
192 INT230802 Positive_regulation of Positive_regulation of Agt 2 0.40 0.41 0.2
193 INT355529 Negative_regulation of Transcription of Fasl 1 0.26 1.23 0.2
194 INT186021 Positive_regulation of Positive_regulation of Esr1 1 0.08 0 0.19
195 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17
196 INT1770 Positive_regulation of Negative_regulation of Agt 2 0.49 1.09 0.17
197 INT256015 Negative_regulation of Regulation of Agt 1 0.18 0.16 0.17
198 INT79914 Positive_regulation of Negative_regulation of Agt 1 0.50 0.19 0.17
199 INT291955 Positive_regulation of Protein_catabolism of Esr1 1 0.06 0.14 0.17
200 INT269777 Regulation of Regulation of Esr1 2 0.02 1.17 0.16
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